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Open data
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Basic information
Entry | Database: PDB / ID: 1meq | ||||||
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Title | HIV gp120 C5 | ||||||
![]() | Exterior Membrane Glycoprotein (GP120) | ||||||
![]() | VIRAL PROTEIN / HIV / AIDS / gp120 / gp41 | ||||||
Function / homology | ![]() virus-mediated perturbation of host defense response => GO:0019049 / : / virion component => GO:0044423 / Dectin-2 family / stimulatory C-type lectin receptor signaling pathway / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell ...virus-mediated perturbation of host defense response => GO:0019049 / : / virion component => GO:0044423 / Dectin-2 family / stimulatory C-type lectin receptor signaling pathway / positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / membrane => GO:0016020 / viral protein processing / fusion of virus membrane with host plasma membrane / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / host cell plasma membrane / structural molecule activity / virion membrane Similarity search - Function | ||||||
Method | SOLUTION NMR / torsion angle dynamics | ||||||
Model type details | minimized average | ||||||
![]() | Caffrey, M. / Jacobs, A. / Guilhaudis, L. | ||||||
![]() | ![]() Title: Solution Structure of the HIV gp120 C5 Domain Authors: Guilhaudis, L. / Jacobs, A. / Caffrey, M. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 16.5 KB | Display | ![]() |
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PDB format | ![]() | 10.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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1 |
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NMR ensembles |
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Components
#1: Protein/peptide | Mass: 2667.245 Da / Num. of mol.: 1 / Fragment: Residues (484-506) / Source method: obtained synthetically Details: The peptide was chemically synthesized. The sequence of the peptide is naturally found in Human immunodeficiency virus type 1 (HIV-1). References: UniProt: P19549 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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NMR experiment | Type: 2D NOESY |
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Sample preparation
Details | Contents: 1mM HIV gp120 C5 at natural abundance Solvent system: 40% TFE, 50 mM phoshpate buffer, 55% H2O, 5% D2O |
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Sample conditions | Ionic strength: 70 mM / pH: 6 / Pressure: 1 atm / Temperature: 300 K |
Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M |
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Radiation wavelength | Relative weight: 1 |
NMR spectrometer | Type: Bruker DMX / Manufacturer: Bruker / Model: DMX / Field strength: 600 MHz |
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Processing
NMR software |
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Refinement | Method: torsion angle dynamics / Software ordinal: 1 / Details: 190 distance restraints, 47 dihedral restraints | ||||||||||||
NMR representative | Selection criteria: minimized average structure | ||||||||||||
NMR ensemble | Conformers submitted total number: 1 |