+データを開く
-基本情報
登録情報 | データベース: PDB / ID: 1mbh | ||||||
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タイトル | MOUSE C-MYB DNA-BINDING DOMAIN REPEAT 2 | ||||||
要素 | C-MYB | ||||||
キーワード | DNA BINDING PROTEIN / PROTOONCOGENE PRODUCT / DNA-BINDING PROTEIN | ||||||
機能・相同性 | 機能・相同性情報 positive regulation of testosterone secretion / myeloid cell development / positive regulation of hepatic stellate cell proliferation / positive regulation of hepatic stellate cell activation / positive regulation of transforming growth factor beta production / embryonic digestive tract development / stem cell division / myeloid cell differentiation / cellular response to interleukin-6 / WD40-repeat domain binding ...positive regulation of testosterone secretion / myeloid cell development / positive regulation of hepatic stellate cell proliferation / positive regulation of hepatic stellate cell activation / positive regulation of transforming growth factor beta production / embryonic digestive tract development / stem cell division / myeloid cell differentiation / cellular response to interleukin-6 / WD40-repeat domain binding / homeostasis of number of cells / positive regulation of collagen biosynthetic process / positive regulation of glial cell proliferation / spleen development / B cell differentiation / thymus development / cellular response to leukemia inhibitory factor / positive regulation of smooth muscle cell proliferation / G1/S transition of mitotic cell cycle / RNA polymerase II transcription regulator complex / calcium ion transport / positive regulation of neuron apoptotic process / mitotic cell cycle / regulation of gene expression / DNA-binding transcription activator activity, RNA polymerase II-specific / in utero embryonic development / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / DNA binding / nucleoplasm / nucleus / cytosol 類似検索 - 分子機能 | ||||||
生物種 | Mus musculus (ハツカネズミ) | ||||||
手法 | 溶液NMR | ||||||
データ登録者 | Ogata, K. / Morikawa, S. / Nakamura, H. / Hojo, H. / Yoshimura, S. / Zhang, R. / Aimoto, S. / Ametani, Y. / Hirata, Z. / Sarai, A. ...Ogata, K. / Morikawa, S. / Nakamura, H. / Hojo, H. / Yoshimura, S. / Zhang, R. / Aimoto, S. / Ametani, Y. / Hirata, Z. / Sarai, A. / Ishii, S. / Nishimura, Y. | ||||||
引用 | ジャーナル: Nat.Struct.Biol. / 年: 1995 タイトル: Comparison of the free and DNA-complexed forms of the DNA-binding domain from c-Myb. 著者: Ogata, K. / Morikawa, S. / Nakamura, H. / Hojo, H. / Yoshimura, S. / Zhang, R. / Aimoto, S. / Ametani, Y. / Hirata, Z. / Sarai, A. / Ishii, S. / Nishimura, Y. #1: ジャーナル: Cell(Cambridge,Mass.) / 年: 1994 タイトル: Solution Structure of a Specific DNA Complex of the Myb DNA-Binding Domain with Cooperative Recognition Helices 著者: Ogata, K. / Morikawa, S. / Nakamura, H. / Sekikawa, A. / Inoue, T. / Kanai, H. / Sarai, A. / Ishii, S. / Nishimura, Y. #2: ジャーナル: Proc.Natl.Acad.Sci.USA / 年: 1992 タイトル: Solution Structure of a DNA-Binding Unit of Myb: A Helix-Turn-Helix-Related Motif with Conserved Tryptophans Forming a Hydrophobic Core 著者: Ogata, K. / Hojo, H. / Aimoto, S. / Nakai, T. / Nakamura, H. / Sarai, A. / Ishii, S. / Nishimura, Y. | ||||||
履歴 |
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-構造の表示
構造ビューア | 分子: MolmilJmol/JSmol |
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-ダウンロードとリンク
-ダウンロード
PDBx/mmCIF形式 | 1mbh.cif.gz | 867.2 KB | 表示 | PDBx/mmCIF形式 |
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PDB形式 | pdb1mbh.ent.gz | 730.1 KB | 表示 | PDB形式 |
PDBx/mmJSON形式 | 1mbh.json.gz | ツリー表示 | PDBx/mmJSON形式 | |
その他 | その他のダウンロード |
-検証レポート
文書・要旨 | 1mbh_validation.pdf.gz | 340.2 KB | 表示 | wwPDB検証レポート |
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文書・詳細版 | 1mbh_full_validation.pdf.gz | 560.9 KB | 表示 | |
XML形式データ | 1mbh_validation.xml.gz | 35.9 KB | 表示 | |
CIF形式データ | 1mbh_validation.cif.gz | 62.9 KB | 表示 | |
アーカイブディレクトリ | https://data.pdbj.org/pub/pdb/validation_reports/mb/1mbh ftp://data.pdbj.org/pub/pdb/validation_reports/mb/1mbh | HTTPS FTP |
-関連構造データ
-リンク
-集合体
登録構造単位 |
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1 |
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NMR アンサンブル |
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-要素
#1: タンパク質 | 分子量: 6300.351 Da / 分子数: 1 / 由来タイプ: 組換発現 / 由来: (組換発現) Mus musculus (ハツカネズミ) / 参照: UniProt: P06876 |
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-実験情報
-実験
実験 | 手法: 溶液NMR |
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-試料調製
試料状態 | pH: 6.8 / 温度: 290 K |
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結晶化 | *PLUS 手法: other / 詳細: NMR |
-解析
ソフトウェア | 名称: AMBER / 分類: 精密化 | |||||||||
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NMR software |
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精密化 | ソフトェア番号: 1 詳細: A TOTAL OF 50 STRUCTURES WERE CALCULATED. THE COORDINATES OF THE RESTRAINTED MINIMIZED AVERAGED STRUCTURE WERE OBTAINED BY AVERAGING THE COORDINATES OF THE INDIVIDUAL STRUCTURES, AND THEN BY ...詳細: A TOTAL OF 50 STRUCTURES WERE CALCULATED. THE COORDINATES OF THE RESTRAINTED MINIMIZED AVERAGED STRUCTURE WERE OBTAINED BY AVERAGING THE COORDINATES OF THE INDIVIDUAL STRUCTURES, AND THEN BY SUBJECTING THE RESULTING COORDINATES TO THE RESTRAINED ENERGY MINIZATION BY PRESTO. THE MINIMIZED AVERAGE STRUCTURE IS PRESENTED IN PROTEIN DATA BANK ENTRY 1MBG. | |||||||||
NMRアンサンブル | 登録したコンフォーマーの数: 50 |