登録情報 | データベース: PDB / ID: 1kl9 |
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タイトル | Crystal structure of the N-terminal segment of Human eukaryotic initiation factor 2alpha |
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要素 | EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 |
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キーワード | TRANSLATION / OB FOLD / HELICAL DOMAIN |
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機能・相同性 | 機能・相同性情報
regulation of translation in response to endoplasmic reticulum stress / translation initiation ternary complex / glial limiting end-foot / response to kainic acid / Cellular response to mitochondrial stress / response to manganese-induced endoplasmic reticulum stress / positive regulation of type B pancreatic cell apoptotic process / negative regulation of translational initiation in response to stress / Response of EIF2AK1 (HRI) to heme deficiency / Recycling of eIF2:GDP ...regulation of translation in response to endoplasmic reticulum stress / translation initiation ternary complex / glial limiting end-foot / response to kainic acid / Cellular response to mitochondrial stress / response to manganese-induced endoplasmic reticulum stress / positive regulation of type B pancreatic cell apoptotic process / negative regulation of translational initiation in response to stress / Response of EIF2AK1 (HRI) to heme deficiency / Recycling of eIF2:GDP / PERK-mediated unfolded protein response / PERK regulates gene expression / eukaryotic translation initiation factor 2 complex / regulation of translational initiation in response to stress / eukaryotic 48S preinitiation complex / Formation of the ternary complex, and subsequently, the 43S complex / Ribosomal scanning and start codon recognition / Translation initiation complex formation / Response of EIF2AK4 (GCN2) to amino acid deficiency / GTP hydrolysis and joining of the 60S ribosomal subunit / L13a-mediated translational silencing of Ceruloplasmin expression / stress granule assembly / translational initiation / translation initiation factor activity / cellular response to amino acid starvation / response to endoplasmic reticulum stress / ABC-family proteins mediated transport / PKR-mediated signaling / cytoplasmic stress granule / cellular response to UV / ribosome binding / cellular response to heat / cellular response to oxidative stress / synapse / RNA binding / extracellular exosome / membrane / nucleus / cytosol類似検索 - 分子機能 Translation initiation factor 2; subunit 1; domain 2 / IF2a, S1-like domain / Translation initiation factor 2, alpha subunit / Translation initiation factor 2, alpha subunit, middle domain superfamily / Translation initiation factor 2, alpha subunit, C-terminal / Eukaryotic translation initiation factor 2 alpha subunit / S1 domain profile. / Ribosomal protein S1-like RNA-binding domain / S1 RNA binding domain / S1 domain ...Translation initiation factor 2; subunit 1; domain 2 / IF2a, S1-like domain / Translation initiation factor 2, alpha subunit / Translation initiation factor 2, alpha subunit, middle domain superfamily / Translation initiation factor 2, alpha subunit, C-terminal / Eukaryotic translation initiation factor 2 alpha subunit / S1 domain profile. / Ribosomal protein S1-like RNA-binding domain / S1 RNA binding domain / S1 domain / Nucleic acid-binding proteins / DNA polymerase; domain 1 / OB fold (Dihydrolipoamide Acetyltransferase, E2P) / Nucleic acid-binding, OB-fold / Beta Barrel / Orthogonal Bundle / Mainly Beta / Mainly Alpha類似検索 - ドメイン・相同性 Eukaryotic translation initiation factor 2 subunit 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 多波長異常分散 / 解像度: 1.9 Å |
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データ登録者 | Nonato, M.C. / Widom, J. / Clardy, J. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2002 タイトル: Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha 著者: Nonato, M.C. / Widom, J. / Clardy, J. |
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履歴 | 登録 | 2001年12月11日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2002年3月11日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月27日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Derived calculations / Version format compliance |
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改定 1.3 | 2018年1月31日 | Group: Advisory / Experimental preparation カテゴリ: exptl_crystal_grow / pdbx_unobs_or_zero_occ_atoms Item: _exptl_crystal_grow.pdbx_details / _exptl_crystal_grow.temp |
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