登録情報 | データベース: PDB / ID: 1hul |
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タイトル | A NOVEL DIMER CONFIGURATION REVEALED BY THE CRYSTAL STRUCTURE AT 2.4 ANGSTROMS RESOLUTION OF HUMAN INTERLEUKIN-5 |
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要素 | INTERLEUKIN-5 |
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キーワード | CYTOKINE |
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機能・相同性 | 機能・相同性情報
positive regulation of eosinophil differentiation / interleukin-5 receptor binding / interleukin-5-mediated signaling pathway / positive regulation of podosome assembly / positive regulation of immunoglobulin production / Interleukin-3, Interleukin-5 and GM-CSF signaling / Interleukin receptor SHC signaling / positive regulation of B cell proliferation / cytokine activity / positive regulation of receptor signaling pathway via JAK-STAT ...positive regulation of eosinophil differentiation / interleukin-5 receptor binding / interleukin-5-mediated signaling pathway / positive regulation of podosome assembly / positive regulation of immunoglobulin production / Interleukin-3, Interleukin-5 and GM-CSF signaling / Interleukin receptor SHC signaling / positive regulation of B cell proliferation / cytokine activity / positive regulation of receptor signaling pathway via JAK-STAT / growth factor activity / positive regulation of peptidyl-tyrosine phosphorylation / RAF/MAP kinase cascade / inflammatory response / immune response / positive regulation of DNA-templated transcription / extracellular space / extracellular region類似検索 - 分子機能 Interleukin-5 / Interleukin 5 / Growth Hormone; Chain: A; - #10 / Four-helical cytokine-like, core / Growth Hormone; Chain: A; / Up-down Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / 解像度: 2.4 Å |
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データ登録者 | Milburn, M.V. |
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引用 | ジャーナル: Nature / 年: 1993 タイトル: A novel dimer configuration revealed by the crystal structure at 2.4 A resolution of human interleukin-5. 著者: Milburn, M.V. / Hassell, A.M. / Lambert, M.H. / Jordan, S.R. / Proudfoot, A.E. / Graber, P. / Wells, T.N. |
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履歴 | 登録 | 1995年3月17日 | 処理サイト: BNL |
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改定 1.0 | 1995年12月7日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年3月24日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2024年6月5日 | Group: Data collection / Database references / Other カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.process_site |
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