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- PDB-1f3k: THREE-DIMENSIONAL SOLUTION STRUCTURE OF OMEGA-CONOTOXIN TXVII, AN... -
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Basic information
Entry | Database: PDB / ID: 1f3k | ||||||
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Title | THREE-DIMENSIONAL SOLUTION STRUCTURE OF OMEGA-CONOTOXIN TXVII, AN L-TYPE CALCIUM CHANNEL BLOCKER | ||||||
![]() | OMEGA-CONOTOXIN TXVII | ||||||
![]() | TOXIN / OMEGA-CONOTOXIN / CYSTINE KNOT MOTIF / TRIPLE-STRANDED ANTIPARALLEL BETA-SHEET / L-TYPE CALCIUM CHANNEL BLOCKER | ||||||
Function / homology | Conotoxin, omega-type, conserved site / Omega-conotoxin family signature. / Conotoxin / Conotoxin / ion channel inhibitor activity / : / toxin activity / extracellular region / Omega-conotoxin TxVII![]() | ||||||
Method | SOLUTION NMR / distance geometry, simulated annealing | ||||||
![]() | Kobayashi, K. / Sasaki, T. / Sato, K. / Kohno, T. | ||||||
![]() | ![]() Title: Three-dimensional solution structure of omega-conotoxin TxVII, an L-type calcium channel blocker. Authors: Kobayashi, K. / Sasaki, T. / Sato, K. / Kohno, T. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 126.5 KB | Display | ![]() |
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PDB format | ![]() | 102.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 337.2 KB | Display | ![]() |
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Full document | ![]() | 473.4 KB | Display | |
Data in XML | ![]() | 19.1 KB | Display | |
Data in CIF | ![]() | 28.5 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: Protein/peptide | Mass: 2841.350 Da / Num. of mol.: 1 / Source method: obtained synthetically Details: This peptide was chemically synthesized. The sequence of this peptide naturally occurs in Conus textile. References: UniProt: P56714 |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||||||||||
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NMR experiment |
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NMR details | Text: This structure was determined using standard 2D homonuclear techniques. |
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Sample preparation
Details |
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Sample conditions | Ionic strength: 0 / pH: 5.6 / Pressure: ambient / Temperature: 288 K | |||||||||
Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
NMR spectrometer | Type: Bruker AMX / Manufacturer: Bruker / Model: AMX / Field strength: 500 MHz |
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Processing
NMR software |
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Refinement | Method: distance geometry, simulated annealing / Software ordinal: 1 Details: The structures are based on a total of 452 restraints, 411 are NOE-derived distance constraints, 20 dihedral angle restraints, 21 distance restraints from hydrogen bonds and disulfide bonds. | ||||||||||||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 100 / Conformers submitted total number: 20 |