+Open data
-Basic information
Entry | Database: PDB / ID: 1dsr | ||||||||||||
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Title | Peptide antibiotic, NMR, 6 structures | ||||||||||||
Components | RAMOPLANIN A2 | ||||||||||||
Keywords | ANTIBIOTIC / RAMOPLANIN / INHIBITOR / GLYCOLIPODESPSIPEPTIDE | ||||||||||||
Function / homology | RAMOPLANIN A2 / (2Z,4E)-7-methylocta-2,4-dienoic acid / : Function and homology information | ||||||||||||
Biological species | ACTINOPLANES SP. (bacteria) | ||||||||||||
Method | SOLUTION NMR | ||||||||||||
Authors | Kurz, M. / Guba, W. | ||||||||||||
Citation | Journal: Biochemistry / Year: 1996 Title: 3D Structure of Ramoplanin: A Potent Inhibitor of Bacterial Cell Wall Synthesis. Authors: Kurz, M. / Guba, W. | ||||||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1dsr.cif.gz | 43.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1dsr.ent.gz | 30.6 KB | Display | PDB format |
PDBx/mmJSON format | 1dsr.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1dsr_validation.pdf.gz | 441.5 KB | Display | wwPDB validaton report |
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Full document | 1dsr_full_validation.pdf.gz | 485.3 KB | Display | |
Data in XML | 1dsr_validation.xml.gz | 6.2 KB | Display | |
Data in CIF | 1dsr_validation.cif.gz | 7.1 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ds/1dsr ftp://data.pdbj.org/pub/pdb/validation_reports/ds/1dsr | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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NMR ensembles |
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-Components
#1: Protein/peptide | Type: Lipoglycopeptide / Class: Antibiotic / Mass: 2111.610 Da / Num. of mol.: 1 / Source method: isolated from a natural source Details: RAMOPLANIN A2 IS A CYCLIC HEPTADECAMER LIPOGLYCODEPSIPEPTIDE. THE SCAFFOLD IS A HEPTA CYCLIC PEPTIDE GLYCOSYLATED BY ONE DISACCHARIDE AND A FATTY ACID AT THE N-TERM. Source: (natural) ACTINOPLANES SP. (bacteria) / Strain: ATCC 33076 / References: NOR: NOR00844, RAMOPLANIN A2 | ||
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#2: Polysaccharide | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose / 2alpha-alpha-mannobiose Source method: isolated from a genetically manipulated source Details: RAMOPLANIN A2 IS A CYCLIC HEPTADECAMER LIPOGLYCODEPSIPEPTIDE. THE SCAFFOLD IS A HEPTA CYCLIC PEPTIDE GLYCOSYLATED BY ONE DISACCHARIDE AND A FATTY ACID AT THE N-TERM. References: RAMOPLANIN A2 | ||
#3: Chemical | Type: Lipoglycopeptide / Class: Antibiotic / Mass: 154.206 Da / Num. of mol.: 1 / Source method: obtained synthetically / Formula: C9H14O2 Details: RAMOPLANIN A2 IS A CYCLIC HEPTADECAMER LIPOGLYCODEPSIPEPTIDE. THE SCAFFOLD IS A HEPTA CYCLIC PEPTIDE GLYCOSYLATED BY ONE DISACCHARIDE AND A FATTY ACID AT THE N-TERM. References: RAMOPLANIN A2 Compound details | RAMOPLANIN IS A CYCLIC LIPOGLYCOPEPTIDE. HERE, RAMOPLANIN IS REPRESENTED BY GROUPING TOGETHER THE ...RAMOPLANIN | |
-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR |
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NMR experiment | Type: NOESY |
-Sample preparation
Sample conditions | pH: 4.6 / Temperature: 313 K |
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Crystal grow | *PLUS Method: other / Details: NMR |
-NMR measurement
NMR spectrometer | Type: Bruker AMX 600 / Manufacturer: Bruker / Model: AMX 600 / Field strength: 600 MHz |
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-Processing
NMR ensemble | Conformer selection criteria: ENERGY MINIMIZED SNAPSHOT EVERY 75 PS Conformers calculated total number: 450 / Conformers submitted total number: 6 |
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