登録情報 データベース : PDB / ID : 1ckx 構造の表示 ダウンロードとリンクタイトル Cystic fibrosis transmembrane conductance regulator: Solution structures of peptides based on the Phe508 region, the most common site of disease-causing Delta-F508 mutation 要素Cystic fibrosis transmembrane conductance regulator (CFTR) 詳細 キーワード METAL TRANSPORT / P26_TFE / CYSTIC FIBROSIS / PEPTIDES機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Sec61 translocon complex binding / channel-conductance-controlling ATPase / intracellularly ATP-gated chloride channel activity / positive regulation of enamel mineralization / transepithelial water transport / intracellular pH elevation / amelogenesis / chloride channel inhibitor activity / multicellular organismal-level water homeostasis / membrane hyperpolarization ... Sec61 translocon complex binding / channel-conductance-controlling ATPase / intracellularly ATP-gated chloride channel activity / positive regulation of enamel mineralization / transepithelial water transport / intracellular pH elevation / amelogenesis / chloride channel inhibitor activity / multicellular organismal-level water homeostasis / membrane hyperpolarization / cholesterol transport / bicarbonate transport / bicarbonate transmembrane transporter activity / vesicle docking involved in exocytosis / chloride transmembrane transporter activity / sperm capacitation / chloride channel activity / cholesterol biosynthetic process / positive regulation of exocytosis / positive regulation of insulin secretion involved in cellular response to glucose stimulus / chloride channel complex / ABC-type transporter activity / cellular response to cAMP / cellular response to forskolin / chloride transmembrane transport / isomerase activity / response to endoplasmic reticulum stress / establishment of localization in cell / PDZ domain binding / recycling endosome membrane / early endosome membrane / protein-folding chaperone binding / early endosome / apical plasma membrane / endoplasmic reticulum membrane / enzyme binding / cell surface / ATP hydrolysis activity / ATP binding / membrane / nucleus / plasma membrane / cytosol 類似検索 - 分子機能 : / CFTR regulator domain / Cystic fibrosis TM conductance regulator (CFTR), regulator domain / Cystic fibrosis transmembrane conductance regulator / ABC transporter transmembrane region / ABC transporter type 1, transmembrane domain / ABC transporter integral membrane type-1 fused domain profile. / ABC transporter type 1, transmembrane domain superfamily / ABC transporter-like, conserved site / ABC transporters family signature. ... : / CFTR regulator domain / Cystic fibrosis TM conductance regulator (CFTR), regulator domain / Cystic fibrosis transmembrane conductance regulator / ABC transporter transmembrane region / ABC transporter type 1, transmembrane domain / ABC transporter integral membrane type-1 fused domain profile. / ABC transporter type 1, transmembrane domain superfamily / ABC transporter-like, conserved site / ABC transporters family signature. / ABC transporter / ABC transporter-like, ATP-binding domain / ATP-binding cassette, ABC transporter-type domain profile. / ATPases associated with a variety of cellular activities / AAA+ ATPase domain / P-loop containing nucleoside triphosphate hydrolase 類似検索 - ドメイン・相同性 Cystic fibrosis transmembrane conductance regulator 類似検索 - 構成要素手法 溶液NMR / distance geometry 詳細データ登録者 Massiah, M.A. / Ko, Y.H. / Pedersen, P.L. / Mildvan, A.S. 引用ジャーナル : Biochemistry / 年 : 1999タイトル : Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation.著者 : Massiah, M.A. / Ko, Y.H. / Pedersen, P.L. / Mildvan, A.S. 履歴 登録 1999年4月26日 登録サイト : BNL / 処理サイト : RCSB改定 1.0 1999年5月4日 Provider : repository / タイプ : Initial release改定 1.1 2008年4月26日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2022年2月16日 Group : Database references / Derived calculationsカテゴリ : database_2 / pdbx_struct_assembly / pdbx_struct_oper_listItem : _database_2.pdbx_DOI / _database_2.pdbx_database_accession改定 1.4 2023年12月27日 Group : Data collection / カテゴリ : chem_comp_atom / chem_comp_bond
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