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Yorodumi- PDB-1aat: OXOGLUTARATE-INDUCED CONFORMATIONAL CHANGES IN CYTOSOLIC ASPARTAT... -
+Open data
-Basic information
Entry | Database: PDB / ID: 1aat | |||||||||
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Title | OXOGLUTARATE-INDUCED CONFORMATIONAL CHANGES IN CYTOSOLIC ASPARTATE AMINOTRANSFERASE | |||||||||
Components | CYTOSOLIC ASPARTATE AMINOTRANSFERASE | |||||||||
Keywords | AMINOTRANSFERASE | |||||||||
Function / homology | Function and homology information Amino acid metabolism / phosphatidylserine decarboxylase activity / glutamate catabolic process to aspartate / glutamate catabolic process to 2-oxoglutarate / cysteine transaminase / L-cysteine transaminase activity / aspartate biosynthetic process / Gluconeogenesis / aspartate catabolic process / glycerol biosynthetic process ...Amino acid metabolism / phosphatidylserine decarboxylase activity / glutamate catabolic process to aspartate / glutamate catabolic process to 2-oxoglutarate / cysteine transaminase / L-cysteine transaminase activity / aspartate biosynthetic process / Gluconeogenesis / aspartate catabolic process / glycerol biosynthetic process / aspartate metabolic process / glutamate metabolic process / 2-oxoglutarate metabolic process / oxaloacetate metabolic process / aspartate transaminase / L-aspartate:2-oxoglutarate aminotransferase activity / fatty acid homeostasis / response to glucocorticoid / Notch signaling pathway / gluconeogenesis / cellular response to insulin stimulus / pyridoxal phosphate binding / cytosol Similarity search - Function | |||||||||
Biological species | Gallus gallus (chicken) | |||||||||
Method | X-RAY DIFFRACTION / Resolution: 2.8 Å | |||||||||
Authors | Harutyunyan, E.G. / Malashkevich, V.N. | |||||||||
Citation | Journal: DOKL.AKAD.NAUK SSSR / Year: 1982 Title: Conformational changes in cytosol aspartate aminotransferase induced by oxoglutarate Authors: Malashkevich, V.N. / Kochkina, V.M. / Torchinskii, I.u.M. / Arutiunian, E.G. #1: Journal: Prog.Clin.Biol.Res. / Year: 1982 Title: Aspartate Aminotranferase from Chicken Heart Cytosol. Three-Dimensional Structure and Coenzyme Reorientations in the Active Site Authors: Torchinsky, Yu.M. / Harutyunyan, E.G. / Malashkevich, V.N. / Kochkina, V.M. / Makarov, V.L. / Braunstein, A.E. #2: Journal: FEBS Lett. / Year: 1982 Title: Three-Dimensional Structure at 3.2 Angstroms Resolution of the Complex of Cytosolic Aspartate Aminotransferase from Chicken Heart with 2-Oxoglutarate Authors: Harutyunyan, E.G. / Malashkevich, V.N. / Tersyan, S.S. / Kochkina, V.M. / Torchinsky, Yu.M. / Braunstein, A.E. #3: Journal: FEBS Lett. / Year: 1979 Title: Primary Structure of Cytoplasmic Aspartate Aminotransferase from Chicken Heart and its Homology with Pig Heart Isoenzymes Authors: Shlyapnikov, S.V. / Myasnikov, A.N. / Severin, E.S. / Myagkova, M.A. / Torchinsky, Yu.M. / Braunstein, A.E. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1aat.cif.gz | 37.8 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1aat.ent.gz | 20.1 KB | Display | PDB format |
PDBx/mmJSON format | 1aat.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/aa/1aat ftp://data.pdbj.org/pub/pdb/validation_reports/aa/1aat | HTTPS FTP |
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-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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1 |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS oper: (Code: given Matrix: (-0.224554, -0.974529, 0.028477), Vector: |
-Components
#1: Protein | Mass: 45869.996 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) Gallus gallus (chicken) / References: UniProt: P00504, aspartate transaminase Sequence details | THE RESIDUE NUMBERING IS BASED ON THE SEQUENCE HOMOLOGY WITH PIG CYTOSOLIC ASPARTATE ...THE RESIDUE NUMBERING IS BASED ON THE SEQUENCE HOMOLOGY WITH PIG CYTOSOLIC ASPARTATE AMINOTRANS | |
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-Experimental details
-Experiment
Experiment | Method: X-RAY DIFFRACTION |
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-Sample preparation
Crystal | Density Matthews: 2.51 Å3/Da / Density % sol: 51.02 % |
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-Data collection
Radiation | Scattering type: x-ray |
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Radiation wavelength | Relative weight: 1 |
-Processing
Refinement | Highest resolution: 2.8 Å | ||||||||||||
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Refinement step | Cycle: LAST / Highest resolution: 2.8 Å
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