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- EMDB-47791: Mouse mitoribosome large subunit assembly intermediate bound to N... -

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Basic information

Entry
Database: EMDB / ID: EMD-47791
TitleMouse mitoribosome large subunit assembly intermediate bound to NSUN4, METRF4, GTPBP7, GTPBP10 and the MALSU1-L0R8F8-mt-ACP complex (without uL16m), State B1 (SAMC knock-out)
Map data
Sample
  • Complex: mitoribosome large subunit assembly intermediate
    • RNA: x 2 types
    • Protein or peptide: x 56 types
  • Ligand: x 4 types
Keywordsmitochondria / ribosome assembly / large subunit / ribosome
Function / homology
Function and homology information


Mitochondrial ribosome-associated quality control / Mitochondrial translation elongation / mitochondrial small ribosomal subunit assembly / mRNA (cytidine-5-)-methyltransferase activity / regulation of respiratory system process / regulation of mitochondrial transcription / Mitochondrial translation termination / mitochondrial RNA catabolic process / regulation of mitochondrial translation / negative regulation of mitochondrial translation ...Mitochondrial ribosome-associated quality control / Mitochondrial translation elongation / mitochondrial small ribosomal subunit assembly / mRNA (cytidine-5-)-methyltransferase activity / regulation of respiratory system process / regulation of mitochondrial transcription / Mitochondrial translation termination / mitochondrial RNA catabolic process / regulation of mitochondrial translation / negative regulation of mitochondrial translation / rRNA (cytosine-C5-)-methyltransferase activity / mitochondrial large ribosomal subunit assembly / Protein lipoylation / Mitochondrial Fatty Acid Beta-Oxidation / negative regulation of ribosome biogenesis / Complex I biogenesis / positive regulation of mitochondrial translation / Respiratory electron transport / rRNA import into mitochondrion / ribonuclease III activity / mitochondrial translational termination / mitochondrial translational elongation / mitochondrial ribosome assembly / Mitochondrial protein degradation / translation release factor activity, codon nonspecific / camera-type eye development / mitochondrial fission / iron-sulfur cluster assembly complex / mitochondrial large ribosomal subunit binding / mitochondrial large ribosomal subunit / peptidyl-tRNA hydrolase / translation release factor activity / mitochondrial [2Fe-2S] assembly complex / mitochondrial ribosome / rRNA methylation / mitochondrial small ribosomal subunit / peptidyl-tRNA hydrolase activity / [2Fe-2S] cluster assembly / mitochondrial translation / iron-sulfur cluster assembly / ribosomal large subunit binding / proton motive force-driven mitochondrial ATP synthesis / mitochondrial respiratory chain complex I assembly / respiratory chain complex I / RNA processing / rescue of stalled cytosolic ribosome / cytosolic ribosome / Transferases; Transferring one-carbon groups; Methyltransferases / aerobic respiration / cellular response to leukemia inhibitory factor / ribosomal large subunit biogenesis / mitochondrion organization / fibrillar center / fatty acid biosynthetic process / rRNA processing / cell junction / double-stranded RNA binding / large ribosomal subunit / ribosome biogenesis / heart development / 5S rRNA binding / small ribosomal subunit rRNA binding / large ribosomal subunit rRNA binding / mitochondrial inner membrane / negative regulation of translation / rRNA binding / nuclear body / structural constituent of ribosome / ribosome / translation / mitochondrial matrix / ribonucleoprotein complex / protein domain specific binding / nucleotide binding / GTPase activity / mRNA binding / apoptotic process / GTP binding / nucleolus / structural molecule activity / magnesium ion binding / mitochondrion / RNA binding / nucleoplasm / metal ion binding / nucleus / plasma membrane / cytosol
Similarity search - Function
GTPase, MTG1 / GTP1/OBG domain / GTP-binding protein Obg/CgtA / GTP1/OBG domain superfamily / OBG-type GTPase / GTP1/OBG / Obg domain profile. / Mitochondrial termination factor repeats / Transcription termination factor, mitochondrial/chloroplastic / MTERF superfamily, mitochondrial/chloroplastic ...GTPase, MTG1 / GTP1/OBG domain / GTP-binding protein Obg/CgtA / GTP1/OBG domain superfamily / OBG-type GTPase / GTP1/OBG / Obg domain profile. / Mitochondrial termination factor repeats / Transcription termination factor, mitochondrial/chloroplastic / MTERF superfamily, mitochondrial/chloroplastic / mTERF / MIEF1-MP, LYR domain / Protein Iojap/ribosomal silencing factor RsfS / Ribosomal silencing factor during starvation / SAM-dependent methyltransferase RsmB/NOP2-type / RNA (C5-cytosine) methyltransferase / : / 16S rRNA methyltransferase RsmB/F / SAM-dependent MTase RsmB/NOP-type domain profile. / GTP-binding protein, orthogonal bundle domain superfamily / : / Ribosomal protein L55, mitochondrial / Mitochondrial ribosomal protein L55 superfamily / : / Mitochondrial ribosomal protein L55 / Mitochondrial ribosomal protein L48 / 39S ribosomal protein L40, mitochondrial / Ribosomal protein S30, mitochondrial / Ribosomal protein L53, mitochondrial / 39S ribosomal protein L53/MRP-L53 / 39S ribosomal protein L42, mitochondrial / Mitochondrial 28S ribosomal protein S32 / Ribosomal protein L37, mitochondrial / Mitochondrial ribosomal protein L37 / Ribosomal protein 63, mitochondrial / Growth arrest/ DNA-damage-inducible protein-interacting protein 1 / Ribosomal protein L35, mitochondrial / Ribosomal protein L51, mitochondrial / Growth arrest and DNA-damage-inducible proteins-interacting protein 1 / Mitochondrial ribosomal subunit / Mitochondrial ribosome protein 63 / Ribosomal protein L37/S30 / Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily / : / : / Mitochondrial 28S ribosomal protein S30 (PDCD9) / 39S ribosomal protein L52, mitochondrial / Mitoribosomal protein mL52 / : / MRPL44, double-stranded RNA binding domain / : / MRPL44 dsRNA-binding domain / Large ribosomal subunit protein mL44, endonuclease domain / Ribosomal protein L28/L40, mitochondrial / Mitochondrial ribosomal protein L28 / : / : / Large ribosomal subunit protein bL9m C-terminal domain / Large ribosomal subunit protein bL9m N-terminal domain / Tim44-like domain / Tim44-like domain / Tim44 / : / : / Mitochondrial ribosomal protein L46 NUDIX / Ribosomal protein L50, mitochondria / Ribosomal subunit 39S / Ribosomal protein L46, N-terminal / 39S mitochondrial ribosomal protein L46 / Ribosomal protein L49/IMG2 / Mitochondrial large subunit ribosomal protein (Img2) / Ribosomal protein L27/L41, mitochondrial / : / Mitochondrial ribosomal protein L27 / Circularly permuted (CP)-type guanine nucleotide-binding (G) domain / Circularly permuted (CP)-type guanine nucleotide-binding (G) domain profile. / 39S ribosomal protein L46, mitochondrial / Ribosomal protein L47, mitochondrial / MRP-L47 superfamily, mitochondrial / 39S ribosomal protein L43/54S ribosomal protein L51 / Mitochondrial 39-S ribosomal protein L47 (MRP-L47) / Phosphatidylethanolamine-binding protein, eukaryotic / Phosphatidylethanolamine-binding protein / Phosphatidylethanolamine-binding protein / OBG-type guanine nucleotide-binding (G) domain / OBG-type guanine nucleotide-binding (G) domain profile. / PEBP-like superfamily / Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily / TGS-like / TGS domain profile. / TGS / Peptide chain release factor class I / RF-1 domain / 50S ribosome-binding GTPase / Ribonuclease III, endonuclease domain superfamily / GTP binding domain / Double stranded RNA-binding domain (dsRBD) profile. / Double-stranded RNA-binding domain / Complex 1 LYR protein domain / Complex 1 protein (LYR family)
Similarity search - Domain/homology
Predicted gene, 55359 / Large ribosomal subunit protein uL23m / Large ribosomal subunit protein uL10m / Large ribosomal subunit protein mL43 / Large ribosomal subunit protein uL22m / Transcription termination factor 4, mitochondrial / Large ribosomal subunit protein mL48 / GTP-binding protein 10 / Large ribosomal subunit protein mL38 / Large ribosomal subunit protein uL29m ...Predicted gene, 55359 / Large ribosomal subunit protein uL23m / Large ribosomal subunit protein uL10m / Large ribosomal subunit protein mL43 / Large ribosomal subunit protein uL22m / Transcription termination factor 4, mitochondrial / Large ribosomal subunit protein mL48 / GTP-binding protein 10 / Large ribosomal subunit protein mL38 / Large ribosomal subunit protein uL29m / Large ribosomal subunit protein mL62 / Mitochondrial ribosome-associated GTPase 1 / Large ribosomal subunit protein mL50 / Large ribosomal subunit protein mL37 / Large ribosomal subunit protein mL66 / Large ribosomal subunit protein bL36m / Large ribosomal subunit protein bL34m / Large ribosomal subunit protein bL27m / Large ribosomal subunit protein bL9m / Large ribosomal subunit protein uL3m / Large ribosomal subunit protein uL15m / Large ribosomal subunit protein mL42 / Large ribosomal subunit protein mL54 / Large ribosomal subunit protein mL51 / Large ribosomal subunit protein uL24m / Large ribosomal subunit protein mL49 / Large ribosomal subunit protein uL11m / Large ribosomal subunit protein mL63 / Large ribosomal subunit protein bL20m / Large ribosomal subunit protein uL18m / Large ribosomal subunit protein bL35m / Large ribosomal subunit protein mL41 / Large ribosomal subunit protein bL33m / Acyl carrier protein, mitochondrial / Large ribosomal subunit protein mL64 / Mitochondrial assembly of ribosomal large subunit protein 1 / Large ribosomal subunit protein mL44 / 5-cytosine rRNA methyltransferase NSUN4 / Large ribosomal subunit protein mL55 / Large ribosomal subunit protein mL65 / Large ribosomal subunit protein mL45 / Large ribosomal subunit protein mL52 / Large ribosomal subunit protein bL28m / Large ribosomal subunit protein mL53 / Large ribosomal subunit protein uL14m / Large ribosomal subunit protein bL21m / Large ribosomal subunit protein uL13m / Large ribosomal subunit protein bL19m / Large ribosomal subunit protein uL2m / Large ribosomal subunit protein uL30m / Large ribosomal subunit protein bL17m / Large ribosomal subunit protein bL32m / Large ribosomal subunit protein uL4m / Large ribosomal subunit protein mL46 / Large ribosomal subunit protein mL39 / Large ribosomal subunit protein mL40
Similarity search - Component
Biological speciesMus musculus (house mouse)
Methodsingle particle reconstruction / cryo EM / Resolution: 3.62 Å
AuthorsSingh V / Glasgow RIC / Rorbach J / Freyer C / Amunts A / Wredenberg A
Funding support Sweden, Denmark, 3 items
OrganizationGrant numberCountry
Swedish Research Council Sweden
Novo Nordisk Foundation Denmark
Knut and Alice Wallenberg Foundation Sweden
CitationJournal: Nat Commun / Year: 2025
Title: The mitochondrial methylation potential gates mitoribosome assembly.
Authors: Ruth I C Glasgow / Vivek Singh / Lucía Peña-Pérez / Alissa Wilhalm / Marco F Moedas / David Moore / Florian A Rosenberger / Xinping Li / Ilian Atanassov / Mira Saba / Miriam Cipullo / ...Authors: Ruth I C Glasgow / Vivek Singh / Lucía Peña-Pérez / Alissa Wilhalm / Marco F Moedas / David Moore / Florian A Rosenberger / Xinping Li / Ilian Atanassov / Mira Saba / Miriam Cipullo / Joanna Rorbach / Anna Wedell / Christoph Freyer / Alexey Amunts / Anna Wredenberg /
Abstract: S-adenosylmethionine (SAM) is the principal methyl donor in cells and is essential for mitochondrial gene expression, influencing RNA modifications, translation, and ribosome biogenesis. Using direct ...S-adenosylmethionine (SAM) is the principal methyl donor in cells and is essential for mitochondrial gene expression, influencing RNA modifications, translation, and ribosome biogenesis. Using direct long-read RNA sequencing in mouse tissues and embryonic fibroblasts, we show that processing of the mitochondrial ribosomal gene cluster fails in the absence of mitochondrial SAM, leading to an accumulation of unprocessed precursors. Proteomic analysis of ribosome fractions revealed these precursors associated with processing and assembly factors, indicating stalled biogenesis. Structural analysis by cryo-electron microscopy demonstrated that SAM-dependent methylation is required for peptidyl transferase centre formation during mitoribosome assembly. Our findings identify a critical role for SAM in coordinating mitoribosomal RNA processing and large subunit maturation, linking cellular methylation potential to mitochondrial translation capacity.
History
DepositionNov 8, 2024-
Header (metadata) releaseAug 6, 2025-
Map releaseAug 6, 2025-
UpdateAug 6, 2025-
Current statusAug 6, 2025Processing site: RCSB / Status: Released

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Structure visualization

Supplemental images

emd_47791.png

Downloads & links

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Map

FileDownload / File: emd_47791.map.gz / Format: CCP4 / Size: 600.7 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
Projections & slices

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AxesZ (Sec.)Y (Row.)X (Col.)
0.85 Å/pix.
x 540 pix.
= 457.293 Å		0.85 Å/pix.
x 540 pix.
= 457.293 Å		0.85 Å/pix.
x 540 pix.
= 457.293 Å

Surface

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Voxel sizeX=Y=Z: 0.84684 Å
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Contour LevelBy AUTHOR: 0.01
Minimum - Maximum-0.018955471 - 0.048600968
Average (Standard dev.)-0.000031305142 (±0.0022098199)
SymmetrySpace group: 1
Details

EMDB XML:

Map geometry
Axis orderXYZ
Origin000
Dimensions540540540
Spacing540540540
CellA=B=C: 457.2925 Å
α=β=γ: 90.0 °

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Supplemental data

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Additional map: #1

Fileemd_47791_additional_1.map
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Half map: #2

Fileemd_47791_half_map_1.map
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Half map: #1

Fileemd_47791_half_map_2.map
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Sample components

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Entire : mitoribosome large subunit assembly intermediate

EntireName: mitoribosome large subunit assembly intermediate
Components
  • Complex: mitoribosome large subunit assembly intermediate
    • RNA: RNA (1428-MER)
    • RNA: RNA (56-MER)
    • Protein or peptide: 5-cytosine rRNA methyltransferase NSUN4
    • Protein or peptide: Large ribosomal subunit protein uL2m
    • Protein or peptide: Large ribosomal subunit protein uL3m
    • Protein or peptide: Large ribosomal subunit protein uL4m
    • Protein or peptide: Large ribosomal subunit protein bL9m
    • Protein or peptide: Large ribosomal subunit protein uL13m
    • Protein or peptide: Large ribosomal subunit protein uL14m
    • Protein or peptide: Large ribosomal subunit protein uL15m
    • Protein or peptide: Large ribosomal subunit protein bL17m
    • Protein or peptide: Large ribosomal subunit protein uL18m
    • Protein or peptide: Large ribosomal subunit protein bL19m
    • Protein or peptide: Large ribosomal subunit protein bL20m
    • Protein or peptide: Large ribosomal subunit protein bL21m
    • Protein or peptide: Large ribosomal subunit protein uL22m
    • Protein or peptide: Large ribosomal subunit protein uL23m
    • Protein or peptide: Large ribosomal subunit protein uL24m
    • Protein or peptide: Large ribosomal subunit protein bL27m
    • Protein or peptide: Large ribosomal subunit protein bL28m
    • Protein or peptide: Large ribosomal subunit protein uL29m
    • Protein or peptide: Large ribosomal subunit protein uL30m
    • Protein or peptide: Large ribosomal subunit protein bL32m
    • Protein or peptide: Large ribosomal subunit protein bL33m
    • Protein or peptide: Large ribosomal subunit protein bL34m
    • Protein or peptide: Large ribosomal subunit protein bL35m
    • Protein or peptide: Large ribosomal subunit protein bL36m
    • Protein or peptide: Large ribosomal subunit protein mL38
    • Protein or peptide: Large ribosomal subunit protein mL39
    • Protein or peptide: Large ribosomal subunit protein mL43
    • Protein or peptide: Large ribosomal subunit protein mL44
    • Protein or peptide: Large ribosomal subunit protein mL45
    • Protein or peptide: Large ribosomal subunit protein mL46
    • Protein or peptide: Large ribosomal subunit protein mL48
    • Protein or peptide: Large ribosomal subunit protein mL49
    • Protein or peptide: Large ribosomal subunit protein mL50
    • Protein or peptide: Large ribosomal subunit protein mL51
    • Protein or peptide: Large ribosomal subunit protein mL52
    • Protein or peptide: Large ribosomal subunit protein mL53
    • Protein or peptide: Large ribosomal subunit protein mL63
    • Protein or peptide: Large ribosomal subunit protein mL62
    • Protein or peptide: Large ribosomal subunit protein mL64
    • Protein or peptide: Large ribosomal subunit protein mL66
    • Protein or peptide: Large ribosomal subunit protein mL65
    • Protein or peptide: Mitochondrial assembly of ribosomal large subunit protein 1
    • Protein or peptide: Predicted gene, 55359
    • Protein or peptide: Acyl carrier protein, mitochondrial
    • Protein or peptide: Large ribosomal subunit protein mL37
    • Protein or peptide: Large ribosomal subunit protein mL40
    • Protein or peptide: Large ribosomal subunit protein mL41
    • Protein or peptide: Large ribosomal subunit protein mL42
    • Protein or peptide: Large ribosomal subunit protein mL55
    • Protein or peptide: Large ribosomal subunit protein uL10m
    • Protein or peptide: Mitochondrial ribosome-associated GTPase 1
    • Protein or peptide: Large ribosomal subunit protein mL54
    • Protein or peptide: Transcription termination factor 4, mitochondrial
    • Protein or peptide: Large ribosomal subunit protein uL11m
    • Protein or peptide: GTP-binding protein 10
  • Ligand: MAGNESIUM ION
  • Ligand: ZINC ION
  • Ligand: FE2/S2 (INORGANIC) CLUSTER
  • Ligand: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

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Supramolecule #1: mitoribosome large subunit assembly intermediate

SupramoleculeName: mitoribosome large subunit assembly intermediate / type: complex / ID: 1 / Parent: 0
Macromolecule list: #1-#2, #24, #3-#6, #9-#23, #25-#54, #7, #55-#57, #8, #58
Source (natural)Organism: Mus musculus (house mouse)

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Macromolecule #1: RNA (1428-MER)

MacromoleculeName: RNA (1428-MER) / type: rna / ID: 1 / Number of copies: 1
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 508.601906 KDa
SequenceString: AACUAAUCCU AGCCCUAGCC CUACACAAAU AUAAUUAUAC UAUUAUAUAA AUCAAAACAU UUAUCCUACU AAAAGUAUUG GAGAAAGAA AUUCGUACAU CUAGGAGCUA UAGAACUAGU ACCGCAAGGG AAAGAUGAAA GACUAAUUAA AAGUAAGAAC A AGCAAAGA ...String:
AACUAAUCCU AGCCCUAGCC CUACACAAAU AUAAUUAUAC UAUUAUAUAA AUCAAAACAU UUAUCCUACU AAAAGUAUUG GAGAAAGAA AUUCGUACAU CUAGGAGCUA UAGAACUAGU ACCGCAAGGG AAAGAUGAAA GACUAAUUAA AAGUAAGAAC A AGCAAAGA UUAAACCUUG UACCUUUUGC AUAAUGAACU AACUAGAAAA CUUCUAACUA AAAGAAUUAC AGCUAGAAAC CC CGAAACC AAACGAGCUA CCUAAAAACA AUUUUAUGAA UCAACUCGUC UAUGUGGCAA AAUAGUGAGA AGAUUUUUAG GUA GAGGUG AAAAGCCUAA CGAGCUUGGU GAUAGCUGGU UACCCAAAAA AUGAAUUUAA GUUCAAUUUU AAACUUGCUA AAAA AACAA CAAAAUCAAA AAGUAAGUUU AGAUUAUAGC CAAAAGAGGG ACAGCUCUUC UGGAACGGAA AAAACCUUUA AUAGU GAAU AAUUAACAAA ACAGCUUUUA ACCAUUGUAG GCCUAAAAGC AGCCACCAAU AAAGAAAGCG UUCAAGCUCA ACAUAA AAU UUCAAUUAAU UCCAUAAUUU ACACCAACUU CCUAAACUUA AAAUUGGGUU AAUCUAUAAC UUUAUAGAUG CAACACU GU UAGUAUGAGU AACAAGAAUU CCAAUUCUCC AGGCAUACGC GUAUAACAAC UCGGAUAACC AUUGUUAGUU AAUCAGAC U AUAGGCAAUA AUCACACUAU AAAUAAUCCA CCUAUAACUU CUCUGUUAAC CCAACACCGG AAUGCCUAAA GGAAAGAUC CAAAAAGAUA AAAGGAACUC GGCAAACAAG AACCCCGCCU GUUUACCAAA AACAUCACCU CUAGCAUUAC AAGUAUUAGA GGCACUGCC UGCCCAGUGA CUAAAGUUUA ACGGCCGCGG UAUCCUGACC GUGCAAAGGU AGCAUAAUCA CUUGUUCCUU A AUUAGGGA CUAGCAUGAA CGGCUAAACG AGGGUCCAAC UGUCUCUUAU CUUUAAUCAG UGAAAUUGAC CUUUCAGUGA AG AGGCUGA AAUAUAAUAA UAAGACGAGA AGACCCUAUG GAGCUUAAAU UAUAUAACUU AUCUAUUUAA UUUAUUAAAC CUA AUGGCC CAAAAACUAU AGUAUAAGUU UGAAAUUUCG GUUGGGGUGA CCUCGGAGAA UAAAAAAUCC UCCGAAUGAU UAUA ACCUA GACUUACAAG UCAAAGUAAA AUCAACAUAU CUUAUUGACC CAGAUAUAUU UUGAUCAACG GACCAAGUUA CCCUA GGGA UAACAGCGCA AUCCUAUUUA AGAGUUCAUA UCGACAAUUA GGGUUUACGA CCUCGAUGUU GGAUCAGGAC AUCCCA AUG GUGUAGAAGC UAUUAAUGGU UCGUUUGUUC AACGAUUAAA GUCCUACGUG AUCUGAGUUC AGACCGGAGC AAUCCAG GU CGGUUUCUAU CUAUUUACGA UUUCUCCCAG UACGAAAGGA CAAGAGAAAU AGAGCCACCU UACAAAUAAG CGCUCUCA A CUUAAUUUAU GAAUAAAAUC UAAAUAAAAU AUAUACGUAC ACCCUCUAAC CUAGAGAAGG UUA

GENBANK: GENBANK: AB049357.1

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Macromolecule #2: RNA (56-MER)

MacromoleculeName: RNA (56-MER) / type: rna / ID: 2 / Number of copies: 1
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 21.862076 KDa
SequenceString:
GUUAAUGUAG CUUAAUAACA AAGCAAAGCA CUGAAAAUGC UUAGAUGGAU AAUUGUAUCC CAUAAACA

GENBANK: GENBANK: V00665.1

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Macromolecule #3: Large ribosomal subunit protein uL2m

MacromoleculeName: Large ribosomal subunit protein uL2m / type: protein_or_peptide / ID: 3 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 33.396895 KDa
SequenceString: MALCALTSAL RSLSLASAAI TARVPTLLPA AQIQSNVLLQ LPPALVSPSY RPVHMSADRS AKFVSWKSRT KYTVKPVKMR KSGGRDHTG RIRVHGIGGG HKQNYRMIDF LRFRPEKEKA PEPFEEKVVV VRYDPCRSAD IALVAGGSRK RWIIATENMK A GDTILNSN ...String:
MALCALTSAL RSLSLASAAI TARVPTLLPA AQIQSNVLLQ LPPALVSPSY RPVHMSADRS AKFVSWKSRT KYTVKPVKMR KSGGRDHTG RIRVHGIGGG HKQNYRMIDF LRFRPEKEKA PEPFEEKVVV VRYDPCRSAD IALVAGGSRK RWIIATENMK A GDTILNSN HIGRMAVAAQ EGDAHPLGAL PVGTLINNVE SEPGRGAQYI RAAGTCGVLL RKVNGTAIIQ LPSKRQMQVL ES CTATVGR VSNVNHNQRV IGKAGRNRWL GKRPNSGLWQ RKGGWAGRKI RPLPPMKSYV KLPSAAAQN

UniProtKB: Large ribosomal subunit protein uL2m

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Macromolecule #4: Large ribosomal subunit protein uL3m

MacromoleculeName: Large ribosomal subunit protein uL3m / type: protein_or_peptide / ID: 4 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 39.170871 KDa
SequenceString: MPGWRLLAQA GARVLGCGAR GLGADPGLER RKNILFFVRN LHSKSSTWWD EHLSEENLSF VKQLVSDENK TQLTSKLNPL KDEPWPLHP WEPGSFRVGL IALKLGMMPL WTKDGQKHAV TLLQVQDCHV LKYTPKEDHN GKIAALTVGG KTVSRFYKPD S RLEFYRDL ...String:
MPGWRLLAQA GARVLGCGAR GLGADPGLER RKNILFFVRN LHSKSSTWWD EHLSEENLSF VKQLVSDENK TQLTSKLNPL KDEPWPLHP WEPGSFRVGL IALKLGMMPL WTKDGQKHAV TLLQVQDCHV LKYTPKEDHN GKIAALTVGG KTVSRFYKPD S RLEFYRDL GLPPKQIHKI FHVTDNAVIK PGTPLYAAHF RPGQYVDVTA KTIGKGFQGV MKRWGFKGQP ASHGQTKTHR RP GAISTGD IARVWPGTKM PGRMGNQNRT VYGLKVWRVN TKHNIIYVNG SVPGHKNCLV KIKDSTLPAY KDSCKNLPFP TYF PDGDEE ELPEDLFDES VWQPSEPSIT FA

UniProtKB: Large ribosomal subunit protein uL3m

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Macromolecule #5: Large ribosomal subunit protein uL4m

MacromoleculeName: Large ribosomal subunit protein uL4m / type: protein_or_peptide / ID: 5 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 33.120113 KDa
SequenceString: MLRLFQAASR ASLRLSGSRV IHSLAEGAER PAEISEPRDS AGLLDPVLRK CELRIPVHRR PVQAWVESLR GFEQERIGLA ELHPDVFAT APRLDIVHQV AIWQRNFRRI SYANTKTRAE VSGGGRKPWQ QKGSGRARHG SIRSPLWRGG GVAHGPRGPT S YYYMLPMK ...String:
MLRLFQAASR ASLRLSGSRV IHSLAEGAER PAEISEPRDS AGLLDPVLRK CELRIPVHRR PVQAWVESLR GFEQERIGLA ELHPDVFAT APRLDIVHQV AIWQRNFRRI SYANTKTRAE VSGGGRKPWQ QKGSGRARHG SIRSPLWRGG GVAHGPRGPT S YYYMLPMK VRALGLKVAL TVKLMQDDLH IVDSLELPTA DPQYLTELAQ YRHWGSSVLL VDLTHEEMPK NVVAATSGLN SF NLIPAVG LNVYSMLKHQ TLVLTLPSVA FLEDKLLWQD SRYTPLYPFR LPYSDFP

UniProtKB: Large ribosomal subunit protein uL4m

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Macromolecule #6: Large ribosomal subunit protein bL9m

MacromoleculeName: Large ribosomal subunit protein bL9m / type: protein_or_peptide / ID: 6 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 30.2981 KDa
SequenceString: MAASVAPGVR TLWWAGAAWL RQGGIRELFR PRIEGSTPGR DFSLSHYQST VIVERWWKVP LAGEGRKPHL HRRHRVYKLV EDTKHRPKD NLELILTQSV DEIGVRGDLV SVKKSVGRNK LLSQGLAVYA SPENRKLFEE EKSLRREGKL EKIQTKAGEA T VKFLRSCH ...String:
MAASVAPGVR TLWWAGAAWL RQGGIRELFR PRIEGSTPGR DFSLSHYQST VIVERWWKVP LAGEGRKPHL HRRHRVYKLV EDTKHRPKD NLELILTQSV DEIGVRGDLV SVKKSVGRNK LLSQGLAVYA SPENRKLFEE EKSLRREGKL EKIQTKAGEA T VKFLRSCH LEVGMKNNVK WELNPEIVAR HFFKNLGVVV APHALRLPEE PITRWGEYWC DVTVNGLDTV RVPMSVVLFQ KP KTKRYKH WLAQQAAKSV APTNPQAV

UniProtKB: Large ribosomal subunit protein bL9m

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Macromolecule #7: Large ribosomal subunit protein uL10m

MacromoleculeName: Large ribosomal subunit protein uL10m / type: protein_or_peptide / ID: 7 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 29.438631 KDa
SequenceString: MAAAVAGILR GGLPPRAAWL PTLQTVRHGS KAVTRHWRVM HFQRQKLMAI TEYIPPKPAI NPRCLPPPPK PPKEESGLVR LLRQDIVAV FRDNRMIAVC QNVALSAEDK LLLRHQLRKH KIFIKVFPSQ VLKPFLENSK YRNLLPLFVG HNLLLVSEEP K VKEMVRVL ...String:
MAAAVAGILR GGLPPRAAWL PTLQTVRHGS KAVTRHWRVM HFQRQKLMAI TEYIPPKPAI NPRCLPPPPK PPKEESGLVR LLRQDIVAV FRDNRMIAVC QNVALSAEDK LLLRHQLRKH KIFIKVFPSQ VLKPFLENSK YRNLLPLFVG HNLLLVSEEP K VKEMVRVL KSVPFLPLLG GCVDDTILSR QGLVDYAKLP SLDQLQGQLV GGLTHLMAQT RYLLQHQPVQ LTSLLDQYVK EQ NEGDCAT SANEKLHPPD PAPDA

UniProtKB: Large ribosomal subunit protein uL10m

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Macromolecule #8: Large ribosomal subunit protein uL11m

MacromoleculeName: Large ribosomal subunit protein uL11m / type: protein_or_peptide / ID: 8 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 20.714203 KDa
SequenceString: MSKLSRATRT LKKPEAGGVI RSIVRAGQAI PGPPLGPILG QRGVSINQFC KEFNEKTKDI KEGIPLPTKI FIKPDRTFEL KIGQPTVSY FLKAAAGIEK GARHTGKEVA GLVSLKHVYE IACVKAKDDA FAMQDVPLSS VVRSIIGSAR SLGIRVVKDL S AEELEAFQ ...String:
MSKLSRATRT LKKPEAGGVI RSIVRAGQAI PGPPLGPILG QRGVSINQFC KEFNEKTKDI KEGIPLPTKI FIKPDRTFEL KIGQPTVSY FLKAAAGIEK GARHTGKEVA GLVSLKHVYE IACVKAKDDA FAMQDVPLSS VVRSIIGSAR SLGIRVVKDL S AEELEAFQ KERAVFLAAQ KEADLAAQAE AAKK

UniProtKB: Large ribosomal subunit protein uL11m

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Macromolecule #9: Large ribosomal subunit protein uL13m

MacromoleculeName: Large ribosomal subunit protein uL13m / type: protein_or_peptide / ID: 9 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 20.707889 KDa
SequenceString:
MSSFSRAPQQ WATFARMWYL LDGKMQPPGK LAVIASNKLQ GLNKPVYHQL SDCGDHVVII NTRHIAFSGN KWEQKVYSSH TGYPGGFRQ VTAAQLHRKD PVAIVKLAIY GMLPKNLHRR TMMQRLHLFP DEDIPEDILK NLVEELPQPR RVPKRLDEYT Q EEIEAFPR VWTPPDDFRM

UniProtKB: Large ribosomal subunit protein uL13m

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Macromolecule #10: Large ribosomal subunit protein uL14m

MacromoleculeName: Large ribosomal subunit protein uL14m / type: protein_or_peptide / ID: 10 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 15.900487 KDa
SequenceString:
MAALTGLWGS FAHVSRAFSQ RCFSTSGSLS AVQKMTRVRV VDNSALGSTP YHRPPRCIHV YNKSGVGKVG DQILLAIRGQ KKKALIVGH RMPGSRMTPK FDSNNVVLIE DNGNPVGTRI KIPIPTSLRR REGEYSKVLA IAQNFV

UniProtKB: Large ribosomal subunit protein uL14m

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Macromolecule #11: Large ribosomal subunit protein uL15m

MacromoleculeName: Large ribosomal subunit protein uL15m / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 33.595895 KDa
SequenceString: MAGTARGCGT SLDLLRSLPR VSLANLKPSP NSRKRERRPR DRRRGRKCGR GHKGERQRGT RPRLGFEGGQ TPFYIRIPKY GFNEGHSFR HQYQPLSLRR LQYLIDLGRV DPTQPIDLTQ LVNGRGVTIQ PLKRDYGVQL VEEGADTFQA KINIEVQLAS E LAIAAIEK ...String:
MAGTARGCGT SLDLLRSLPR VSLANLKPSP NSRKRERRPR DRRRGRKCGR GHKGERQRGT RPRLGFEGGQ TPFYIRIPKY GFNEGHSFR HQYQPLSLRR LQYLIDLGRV DPTQPIDLTQ LVNGRGVTIQ PLKRDYGVQL VEEGADTFQA KINIEVQLAS E LAIAAIEK NGGVVTTAFY DPRSLEILCK PIPFFLRGQP IPKRMLPPES LVPYYTDAKN RGYLADPAKF PEARLELAMK FG YVLPDIT KDELFRMLSA RKDPRQIFFG LAPGWVVNMA DKKILKPTDE NLLKYYSS

UniProtKB: Large ribosomal subunit protein uL15m

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Macromolecule #12: Large ribosomal subunit protein bL17m

MacromoleculeName: Large ribosomal subunit protein bL17m / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 20.282445 KDa
SequenceString:
MRLSLAAAIS HGRVYRRLGL GPESRIHLLR NLLTGLVRHE RIEATWARAD EMRGYAEKLI DYGKLGDTNE RAMRMADFWL TEKDLIPKL FKVLAPRFQG QNGNYTRMLQ IPNRKEQDRA KMAVIEYKGN YLPPLPLPHR DSNLTLLNQL LLGLQQDLHH N QDASLHSS CTVQTPKT

UniProtKB: Large ribosomal subunit protein bL17m

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Macromolecule #13: Large ribosomal subunit protein uL18m

MacromoleculeName: Large ribosomal subunit protein uL18m / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 20.707789 KDa
SequenceString:
MALRPRFWKC LSVCRKLECG FAALSTSSVP AVQPDVESKE NEAVAPEFTN RNPRNLELLG VARKERGWAT VWPNREFWHR LRVVKTQHH VEAFVEHLNG QVVVSASTRE WAIKKHLYST RNVVACESIG RVLAQRCLEA GINFMVYQPT PWEASSDSIK R LQNAMTES GVMLREPRRI YE

UniProtKB: Large ribosomal subunit protein uL18m

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Macromolecule #14: Large ribosomal subunit protein bL19m

MacromoleculeName: Large ribosomal subunit protein bL19m / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 33.628977 KDa
SequenceString: MAASMAESCR ASLYLARSVR MARPRLAAFA SDACRVCTGP SRFQSTGPSE PGGFKPPPKP VIVDRRRVPE DERRFLSPEF IPPRGRTNP LKFKIERKDM LDRRKVLPIP EFYVGSILRV TTADPYASGK TSQFLGICIK RSGNGLGATF TLRNTIEGQG V EICFELYN ...String:
MAASMAESCR ASLYLARSVR MARPRLAAFA SDACRVCTGP SRFQSTGPSE PGGFKPPPKP VIVDRRRVPE DERRFLSPEF IPPRGRTNP LKFKIERKDM LDRRKVLPIP EFYVGSILRV TTADPYASGK TSQFLGICIK RSGNGLGATF TLRNTIEGQG V EICFELYN PRIQEIQVVK LEKRLDDNLL YLRDALPEYS TFDVNMKPVP QEACQEVPVN KLKVKMKPKP WSKRWERPNF NI KGIRFDL ALTEEQMKEA QKWNKPWIEF DMMREYDTSK IEAALWEEIE ASKKS

UniProtKB: Large ribosomal subunit protein bL19m

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Macromolecule #15: Large ribosomal subunit protein bL20m

MacromoleculeName: Large ribosomal subunit protein bL20m / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 17.631828 KDa
SequenceString:
MVFLTTRLWL RNRLTDRYWR VQEVLKHAQH FRGRKNRCYR LAVRAVTRAF VKCTKARRLK KRNLRTLWIN RITAASQEHG LKYPAFIVN LIKCQVELNR KVLVDLAIYE PKTFKSLAAL AKRRQQEGFA AALGDGKEPE GIFSRVVQYH

UniProtKB: Large ribosomal subunit protein bL20m

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Macromolecule #16: Large ribosomal subunit protein bL21m

MacromoleculeName: Large ribosomal subunit protein bL21m / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 23.40125 KDa
SequenceString: MAAAIAASAL PGAFGRLVSV CSRSILASQG SGSASLWSAS RRFNSQSASY PQGYVPKTSL SSPPWQEVVL PDPVEETRHH AEVVKRVNE LIATGQYGRL FAVVHFASHQ WKVTAEDLIL IENELDIKCG ERIRLEKVLL VGADNFTLLG KPLLRKELVR V EATVIEKT ...String:
MAAAIAASAL PGAFGRLVSV CSRSILASQG SGSASLWSAS RRFNSQSASY PQGYVPKTSL SSPPWQEVVL PDPVEETRHH AEVVKRVNE LIATGQYGRL FAVVHFASHQ WKVTAEDLIL IENELDIKCG ERIRLEKVLL VGADNFTLLG KPLLRKELVR V EATVIEKT ESWPKINMKF RKRKNFRKKK IIVNPQTILR INTIEIAPRL L

UniProtKB: Large ribosomal subunit protein bL21m

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Macromolecule #17: Large ribosomal subunit protein uL22m

MacromoleculeName: Large ribosomal subunit protein uL22m / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 23.847938 KDa
SequenceString: MAAALLRELG ALRVPNLRIW ATQTLRVLPP SCIHTSASLD ISRKWEKKNK IVYPPQLPGE PRRPAEIYHC RRQIKYSKDK MWYLAKMIR GMSIDQALAQ LEFNDKKGAQ IIKEVLLEAQ DMAVRDHNVE FRSNLHIAES TSGRGQCLKR IRYHGRGRFG I MEKVYCHY ...String:
MAAALLRELG ALRVPNLRIW ATQTLRVLPP SCIHTSASLD ISRKWEKKNK IVYPPQLPGE PRRPAEIYHC RRQIKYSKDK MWYLAKMIR GMSIDQALAQ LEFNDKKGAQ IIKEVLLEAQ DMAVRDHNVE FRSNLHIAES TSGRGQCLKR IRYHGRGRFG I MEKVYCHY FVKLVEGPPP PPEVPKTAVD HAKDYIQQLR SRTIIHTL

UniProtKB: Large ribosomal subunit protein uL22m

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Macromolecule #18: Large ribosomal subunit protein uL23m

MacromoleculeName: Large ribosomal subunit protein uL23m / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 17.145607 KDa
SequenceString:
MARNVLYPLY QLGGPQLRVF RTNFFIQLVR PGTAQPEDTV QFRIPMEMTR VDLRNYLEQI YNVPVAAVRT RVQHGSNRRR DHKNVRIKK PDYKVAYVQL AHGQTFTFPD LFPEKDPRSP EPLEEELPQQ RQSSDLRCPG IPSWFGL

UniProtKB: Large ribosomal subunit protein uL23m

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Macromolecule #19: Large ribosomal subunit protein uL24m

MacromoleculeName: Large ribosomal subunit protein uL24m / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 24.986639 KDa
SequenceString: MRLSALLALA SKATSSPFYR YGMSRPGSIA DKRKNPPWSR RRPVVVEPIS DEDWHLFCGD MVEILEGKDA GKQGKVVQVV RQRNWVVLE GLNTHYRYIG RTKDHRGTMI ASEAPLLHHQ VKLVDPVDRK PTEIQWRFTE AGERVRVSTR SGRIIPKPEF P RADGIVPE ...String:
MRLSALLALA SKATSSPFYR YGMSRPGSIA DKRKNPPWSR RRPVVVEPIS DEDWHLFCGD MVEILEGKDA GKQGKVVQVV RQRNWVVLE GLNTHYRYIG RTKDHRGTMI ASEAPLLHHQ VKLVDPVDRK PTEIQWRFTE AGERVRVSTR SGRIIPKPEF P RADGIVPE TWTDGPKDTS VEDALERTYV PRLKTLEEDV MEAMGIQETR RFKKVYWY

UniProtKB: Large ribosomal subunit protein uL24m

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Macromolecule #20: Large ribosomal subunit protein bL27m

MacromoleculeName: Large ribosomal subunit protein bL27m / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 15.973631 KDa
SequenceString:
MAAAALTLRT RAAVTALLSP TAPTALAVRH ASKKTGGSSK NLGGKSRGKH YGIKKMEGHY VHAGNILGTQ RQFRWHPGAH VGLGRNKCL YALEEGIVRY TKDVYVPNPK NTEAVDLVTS LPKGAVLYKT FVHVVPAKPE GTFKLVDML

UniProtKB: Large ribosomal subunit protein bL27m

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Macromolecule #21: Large ribosomal subunit protein bL28m

MacromoleculeName: Large ribosomal subunit protein bL28m / type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 30.221941 KDa
SequenceString: MPLHRYPVHL WQKLRLRQGI CARLPAHFLR SLEEERTPTP VHYKPHGTKF KINPKNGQRE RVEDVPIPVH YPPESQQGLW GGEGLILGY RYANNDKLSK RVKKVWKPQL FTRELYSEIL DKKFTVTVTM RTLDLIDEAY GFDFYILKTP KEDLGSKFGM D LKRGMLLR ...String:
MPLHRYPVHL WQKLRLRQGI CARLPAHFLR SLEEERTPTP VHYKPHGTKF KINPKNGQRE RVEDVPIPVH YPPESQQGLW GGEGLILGY RYANNDKLSK RVKKVWKPQL FTRELYSEIL DKKFTVTVTM RTLDLIDEAY GFDFYILKTP KEDLGSKFGM D LKRGMLLR LARQDPHLHP ENPERRAAIY DKYRSFVIPE AEAEWVGLTL EEALEKQRLL EEKDPVPLFK VYVEELVQRL QE QVLSRPA VVQKRAGDHA

UniProtKB: Large ribosomal subunit protein bL28m

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Macromolecule #22: Large ribosomal subunit protein uL29m

MacromoleculeName: Large ribosomal subunit protein uL29m / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 29.786721 KDa
SequenceString: MAATSLVGIC RRASAFLKAA CSLVNPKDAA HSGCRSSLSL LHKNTPHVTS FLQCKLLHTT LSRKGLEEFF DDPKNWGEEK VKSGASWTC QQLRNKSNED LHKLWYVLLK ERNMLLTLEQ EAKRQRLPMP SPERLEKVVD SMDNVDKVVQ EREDALRLLQ T GQEKPRPG ...String:
MAATSLVGIC RRASAFLKAA CSLVNPKDAA HSGCRSSLSL LHKNTPHVTS FLQCKLLHTT LSRKGLEEFF DDPKNWGEEK VKSGASWTC QQLRNKSNED LHKLWYVLLK ERNMLLTLEQ EAKRQRLPMP SPERLEKVVD SMDNVDKVVQ EREDALRLLQ T GQEKPRPG AWRRDIFGRI VWHKFKQWPI PWYLNKRYNR RRFFAMPYVD RFIRLRIEKH ARIEARKRSL QKKKEKILHA KF PHLSQER KSSSV

UniProtKB: Large ribosomal subunit protein uL29m

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Macromolecule #23: Large ribosomal subunit protein uL30m

MacromoleculeName: Large ribosomal subunit protein uL30m / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 18.38058 KDa
SequenceString:
MAGVLRSAFP RPPCRLQTVK KGAESLIGTE WIRHKFTKSR IPDKVFQPKP EDHEKYGGDP QNPHKLHIVT RIRSTKRRPY WEKDTIKML GLQKAHSPQI HKNIPSVNAK LKVVKHLIRI QPLKLPQGLP TEETMSSTCL KSTGELVVQW HLKPVEQEAK S

UniProtKB: Large ribosomal subunit protein uL30m

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Macromolecule #24: 5-cytosine rRNA methyltransferase NSUN4

MacromoleculeName: 5-cytosine rRNA methyltransferase NSUN4 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
EC number: Transferases; Transferring one-carbon groups; Methyltransferases
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 42.904293 KDa
SequenceString: MAAPVLRCVR KLLKLVDFTP VPRRYRYKKK WATTEPQFTA SRLALQNFDM TYSVQFGDLW PSIRVSLLSE QKYGALVNNF AAWDSVSAK LEQLSAKDFV SEAISHQKLE PESGLSPTPS LDCSPNLRCF TFSRGDVSRF PPARLGSLGL MDYYLMDAAS L LPVLALGL ...String:
MAAPVLRCVR KLLKLVDFTP VPRRYRYKKK WATTEPQFTA SRLALQNFDM TYSVQFGDLW PSIRVSLLSE QKYGALVNNF AAWDSVSAK LEQLSAKDFV SEAISHQKLE PESGLSPTPS LDCSPNLRCF TFSRGDVSRF PPARLGSLGL MDYYLMDAAS L LPVLALGL QHGDTVLDLC AAPGGKTLAL LQTGCCRNLA ANDLSTSRTG RLQKVLHSYV PQDIREGNQV RVTSWDGRKW GE LEGDTYD RVLVDVPCTT DRHSLHEEEN NIFQRSRKKE RQMLPMLQVQ LLAAGLLATK PGGHVVYSTC SLSHLQNEYV VQG AIELLA NQYNIKVQVE DLSHFRKLFM DTFCFFPSCQ VGELVIPNLM VNFGPMYFCK LHRLP

UniProtKB: 5-cytosine rRNA methyltransferase NSUN4

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Macromolecule #25: Large ribosomal subunit protein bL32m

MacromoleculeName: Large ribosomal subunit protein bL32m / type: protein_or_peptide / ID: 25 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 21.766209 KDa
SequenceString:
MAPSLLLLSL PWPVRPGPLQ RCWELLQRQL QQSWSRFVSP PWAPALAVQR PSILTELAHD TCENKENSSF LDSIFWMAAP KNRRTIEVN RCRRRNPQKL IKIKNNIDIC PECGHLKQKH VLCGYCYEKV RQETTKIRQQ IGAQEGGPFR APSVETMVLY T GEKPSEKD QGKRIVERNI KRPSWFTQN

UniProtKB: Large ribosomal subunit protein bL32m

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Macromolecule #26: Large ribosomal subunit protein bL33m

MacromoleculeName: Large ribosomal subunit protein bL33m / type: protein_or_peptide / ID: 26 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 7.431919 KDa
SequenceString:
MLLSAVSFAK SKSKTILVKL VSQAGTGFSF NHKRSRLREK LSLLHYDPIV NKKVLFVEQK KIRSL

UniProtKB: Large ribosomal subunit protein bL33m

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Macromolecule #27: Large ribosomal subunit protein bL34m

MacromoleculeName: Large ribosomal subunit protein bL34m / type: protein_or_peptide / ID: 27 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 10.552479 KDa
SequenceString:
MAFLARCFGC QACRSVALLS GRYLQSRVWM GLPDSWPLLS LQQARGRARG NEYQPSNIKR KHKHGWVRRL STPAGVQVIL RRMLKGRKS LSH

UniProtKB: Large ribosomal subunit protein bL34m

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Macromolecule #28: Large ribosomal subunit protein bL35m

MacromoleculeName: Large ribosomal subunit protein bL35m / type: protein_or_peptide / ID: 28 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 21.546406 KDa
SequenceString:
MAASIFTGAV RAASGIFRPL NVLASSTYRN CARNACLNSS LCTIHFRHIQ TSVVSSAPRL VTSVGHLAYG HTTTVLNRVA TLVPSVLKP PVRALTYCST RKGKRKTVKS VVHRFLRLHS GLWLRRKAGY KKKLWKKSTA RKKRLREFVF CSKTQSKLLD K MTTSFWKR RNWYAGDPYQ MYHDRTNLRV

UniProtKB: Large ribosomal subunit protein bL35m

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Macromolecule #29: Large ribosomal subunit protein bL36m

MacromoleculeName: Large ribosomal subunit protein bL36m / type: protein_or_peptide / ID: 29 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 11.43898 KDa
SequenceString:
MAALLVRSVV ASVVDPFLHL SRLAVKPRVF SSFLLGTLPR AKPCAEVRSV LCGRPLPTLL PSLGFKTKGV IKKRCKDCYK VKRRGRWFI LCKTNPKHKQ RQ

UniProtKB: Large ribosomal subunit protein bL36m

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Macromolecule #30: Large ribosomal subunit protein mL38

MacromoleculeName: Large ribosomal subunit protein mL38 / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 45.099895 KDa
SequenceString: MAAPWWRAAF FGIGRCRGFS TSAFLSRRTP PLGPMPNEDI DVSNLERLEK YRSFERYRRR AEQEARAPHW WRTYREHFVK ETDPKDKID IGLPPPRVSR TQKLLERKHF LRELRANVEE ERAARLRTAS IPLEAVRAEW ERTCGPYHKQ RLAEYYGLYR D LFHGATFV ...String:
MAAPWWRAAF FGIGRCRGFS TSAFLSRRTP PLGPMPNEDI DVSNLERLEK YRSFERYRRR AEQEARAPHW WRTYREHFVK ETDPKDKID IGLPPPRVSR TQKLLERKHF LRELRANVEE ERAARLRTAS IPLEAVRAEW ERTCGPYHKQ RLAEYYGLYR D LFHGATFV PWVPLHVAYA VGEEDLIPVY HGNEVTPTEA SRAPEVTYEA DKDSLWTLLF INLDGHLLEP DAEYVHWLLT NI PSNRVAE GQETCPYLPP FPARGSGFHR FAFLLFKQDK PINFSEDTRP SPCYQLAQRT FRTFDFYKRH QEAMTPAGLA FFQ CRWDDS VTHTFHQLLD MREPVFEFVR PPPYHPKQKR FPHEQPLRYL DRYRDSHEPT YGIY

UniProtKB: Large ribosomal subunit protein mL38

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Macromolecule #31: Large ribosomal subunit protein mL39

MacromoleculeName: Large ribosomal subunit protein mL39 / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 38.603258 KDa
SequenceString: MATAVGRLVL RRPGAGGGAR WRFIATSPAA ELSPTELTEM RNDLFNREKS RQLSLTPRTE KIEVKHVGKT DPGTVFVMNK NISTPYSCA MHLSEWYCSK SILALVDGQP WDMYKPLTKS CEIKFLTFKD PDPKEVNKAY WRSCAMMLGC VIERAFKDDY V VSLVRAPE ...String:
MATAVGRLVL RRPGAGGGAR WRFIATSPAA ELSPTELTEM RNDLFNREKS RQLSLTPRTE KIEVKHVGKT DPGTVFVMNK NISTPYSCA MHLSEWYCSK SILALVDGQP WDMYKPLTKS CEIKFLTFKD PDPKEVNKAY WRSCAMMLGC VIERAFKDDY V VSLVRAPE VPVIAGAFCY DVTLDKRLDE WMPTKENLRS FTKDAHALIY RDLPFETLDV DARVALEIFQ HNKYKVDFIE EK ASQNPER IVKLHRIGDF IDVSEGPLIP RTSVCFQYEV SAVHNLNPSQ PNLIRRFQGL SLPTHLRAQF TIWDKLVERS RKM VTEDEV RQTENTESTQ

UniProtKB: Large ribosomal subunit protein mL39

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Macromolecule #32: Large ribosomal subunit protein mL43

MacromoleculeName: Large ribosomal subunit protein mL43 / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 17.905301 KDa
SequenceString:
MTGRGTSSRF LTSVLHNGLG RYVQQLQRLS LSLSRDAPSS RGAREFVERE VTDFARRNPG VVVYVNPRPC AMPRIVAEYL NGAVREENV NSKSVEEIKS LVQKLADQSG LDVIRIRKPF HTDNPSIQGQ WHPFTNKRTA LHGLRPRELR DSAPASMQAQ

UniProtKB: Large ribosomal subunit protein mL43

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Macromolecule #33: Large ribosomal subunit protein mL44

MacromoleculeName: Large ribosomal subunit protein mL44 / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
EC number: Hydrolases; Acting on ester bonds; Endoribonucleases producing 5'-phosphomonoesters
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 34.912 KDa
SequenceString: PPVRGVKKGF RAAFRFQKEL ERWRLLRCPP PPVRRSEKPN WDYHAEVQAF GSRLQETFSL DLLKTAFINS CYIKSEEAKR QSLGIEKEA ALLNLKDNQE LFEQGLSFSH RCLTQFLEDE FPDLPAEGTE SLVSFLTGEA VVCHVARNLA VEQLTLSAEF P VPLPVLRQ ...String:
PPVRGVKKGF RAAFRFQKEL ERWRLLRCPP PPVRRSEKPN WDYHAEVQAF GSRLQETFSL DLLKTAFINS CYIKSEEAKR QSLGIEKEA ALLNLKDNQE LFEQGLSFSH RCLTQFLEDE FPDLPAEGTE SLVSFLTGEA VVCHVARNLA VEQLTLSAEF P VPLPVLRQ TFFAVIGALL QSSGPERAAL FIRDFLITQM TGKELFEMWT VVNPMGLLVE ELKKRNISAP ESRLTRQSGS TT ALPLYFV GLYCDRKLIA EGPGETVLVA EEEAARVALR KLYGFTENRR PWDYSKPKES PKRAEQTSVA S

UniProtKB: Large ribosomal subunit protein mL44

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Macromolecule #34: Large ribosomal subunit protein mL45

MacromoleculeName: Large ribosomal subunit protein mL45 / type: protein_or_peptide / ID: 34 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 35.463863 KDa
SequenceString: MAAPVPRGLS SLYRTLGWWS RQPILVTQST TVVQVKTKSR FRPPTPEPKY KTEKEFLEYA RKAGLVIPQE RLERPIHLAC TAGIFDPYV PPEGDARMSS LSKEGLTQRT ERLRKNAASQ LAIRKIREFD ANFKTKDFPE KAKDIFIEAH LCLNNSDHDR L HTLVTEHC ...String:
MAAPVPRGLS SLYRTLGWWS RQPILVTQST TVVQVKTKSR FRPPTPEPKY KTEKEFLEYA RKAGLVIPQE RLERPIHLAC TAGIFDPYV PPEGDARMSS LSKEGLTQRT ERLRKNAASQ LAIRKIREFD ANFKTKDFPE KAKDIFIEAH LCLNNSDHDR L HTLVTEHC FPDMVWDLKY KTVRWGFVES LEPAQVVHVR CSGLVNQSNM YGQVTVRLHT RQTLAIYDRF GRLMYGQEDV PK DVLEYVV FERHLMNPYG SWRMHAKIVP AWAPPKQPIL KTLMIPGPQL KPWEEYEETQ GEAQKPQLA

UniProtKB: Large ribosomal subunit protein mL45

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Macromolecule #35: Large ribosomal subunit protein mL46

MacromoleculeName: Large ribosomal subunit protein mL46 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 32.175697 KDa
SequenceString: MAAPVGRTLL GLARGWRQLD RFWAGSSRGL SLEAASSSSR SPWRLSGALC LQRPPLITKA LTPLQEEMAG LLQQIEVERS LYSDHELRA LDEAQRLAKK KADLYDEEQE QGITLAQDLE DMWEQAFLQF RPGARETEAD KKNDRTSLHR KLDRNLVLLV R EKLGDQDV ...String:
MAAPVGRTLL GLARGWRQLD RFWAGSSRGL SLEAASSSSR SPWRLSGALC LQRPPLITKA LTPLQEEMAG LLQQIEVERS LYSDHELRA LDEAQRLAKK KADLYDEEQE QGITLAQDLE DMWEQAFLQF RPGARETEAD KKNDRTSLHR KLDRNLVLLV R EKLGDQDV WMLPQVEWQP GETLRGTAER ILATLSENNM EAKFLGNAPC GHYKFKFPKA IQTESDLGVK VFFFKALLLT GD FVQAGKK SRHVWASKEE LGDYLQPKYL AQVRRFLLDS DGLSCL

UniProtKB: Large ribosomal subunit protein mL46

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Macromolecule #36: Large ribosomal subunit protein mL48

MacromoleculeName: Large ribosomal subunit protein mL48 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 23.989707 KDa
SequenceString: MSGTLGKVLG VWTNTVSKQG FSLLRFRSLG ENPIFSAGGI LWTSRHYKTK PTHGIGRYRH LVKVQEPKKK KAKVELRAIN VGTDYEYGV LNIHLTAYDM SLAESYAQYV HRLCNRLSIK VEESYAMPTK TMEVMRLPDQ GNKMVLDSVL TTHERVVQIS G LSATFAEI ...String:
MSGTLGKVLG VWTNTVSKQG FSLLRFRSLG ENPIFSAGGI LWTSRHYKTK PTHGIGRYRH LVKVQEPKKK KAKVELRAIN VGTDYEYGV LNIHLTAYDM SLAESYAQYV HRLCNRLSIK VEESYAMPTK TMEVMRLPDQ GNKMVLDSVL TTHERVVQIS G LSATFAEI FLEVLQSNLP EGVRLSVREH TEEDFKGRFK ARPELEELLA KLN

UniProtKB: Large ribosomal subunit protein mL48

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Macromolecule #37: Large ribosomal subunit protein mL49

MacromoleculeName: Large ribosomal subunit protein mL49 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 19.161035 KDa
SequenceString:
MAAAVLRAAL QDWRSCLGRS YGRRKLSQTQ GPPDNPGFVE SVDEYQFVER LLPPTKIPEP PKHKHYPTPS GWQPPRDPLP SLPYFVRRS RMHNIPVYKE ITHGNRQMTL IRKVEGDIWA LQKDVEEFLS PLLGKTPITQ VNEVTGTLRI KGYFDEQLKA W LLEKGF

UniProtKB: Large ribosomal subunit protein mL49

+
Macromolecule #38: Large ribosomal subunit protein mL50

MacromoleculeName: Large ribosomal subunit protein mL50 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 18.241043 KDa
SequenceString:
MAALIVSRLA RRGWLWKLPL ATRREFWSRS RKEKEPVVAE TVEEVKKEPV LVCPPLRSRA YTPPSDLQSR LESHIKEVLG SSLPNNWQD ISLDDGHMKF RLLAGLADGL GHAVPNSRLH QMCRVRDVLD FYNVPVQDKS KFDELVASNL PPNLKISWSY

UniProtKB: Large ribosomal subunit protein mL50

+
Macromolecule #39: Large ribosomal subunit protein mL51

MacromoleculeName: Large ribosomal subunit protein mL51 / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 15.132796 KDa
SequenceString:
MAGSVPWAAS RRLWGWVPSA CRSFSLGVPR LAFVRLTLPP PKVVDRWNEK RALFGVYDNI GILGNFEKHP KELIKGPVWL RGWRGNELQ RCVRKKKFVG NRMFIEDLHN LNKRISYLYK HFNRHGKYR

UniProtKB: Large ribosomal subunit protein mL51

+
Macromolecule #40: Large ribosomal subunit protein mL52

MacromoleculeName: Large ribosomal subunit protein mL52 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 13.681875 KDa
SequenceString:
MAALGTWLSS VRRLHCSVVA RAGGQWRLQQ GLAANPSGYG PLTELPDWSF ADGRPAPPMK GQLRRKAQRE KLARRVVLLT QEMDAGIQA WKLRQQKLQE ERKKEHDLKP KGTLLRSPLP NQ

UniProtKB: Large ribosomal subunit protein mL52

+
Macromolecule #41: Large ribosomal subunit protein mL53

MacromoleculeName: Large ribosomal subunit protein mL53 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 12.756635 KDa
SequenceString:
MAAALARLGL RPVKLVRVQF CPFEKNVEST RTFLQTVSSE KVRATNLNCS VIADVRHDGS EPCVDVLFGD GYRLIMRGAH LTTQEMLSA LASHIRDRNA AAASAPGADK VAPGTSTRR

UniProtKB: Large ribosomal subunit protein mL53

+
Macromolecule #42: Large ribosomal subunit protein mL63

MacromoleculeName: Large ribosomal subunit protein mL63 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 11.974847 KDa
SequenceString:
MFLTAVLLRG RIPGRQWIGK HRRPRTVSFQ AKESMIRRLE VEAENHYWLS MPYMTAEQEC GHAAERRAQA FEAIKAAATS KFPKHRYIA DQLDHLNISK KWS

UniProtKB: Large ribosomal subunit protein mL63

+
Macromolecule #43: Large ribosomal subunit protein mL62

MacromoleculeName: Large ribosomal subunit protein mL62 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO / EC number: peptidyl-tRNA hydrolase
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 23.519049 KDa
SequenceString: MATAWGLRWG LSRTGTLLLA PPARCARRAL HRQVDGTTFQ SIYSLDKLYP ESKGADTAWK VPEHAKQASS YIPLDRLSIS YCRSSGPGG QNVNKVNSKA EVRFHLASAD WIEEPVRQKI ALTHKNKINK AGELVLTSES SRYQFRNLAE CLQKIRDMIA E ASQVPKEP ...String:
MATAWGLRWG LSRTGTLLLA PPARCARRAL HRQVDGTTFQ SIYSLDKLYP ESKGADTAWK VPEHAKQASS YIPLDRLSIS YCRSSGPGG QNVNKVNSKA EVRFHLASAD WIEEPVRQKI ALTHKNKINK AGELVLTSES SRYQFRNLAE CLQKIRDMIA E ASQVPKEP SKEDARLQRL RIEKMNRERL RQKRLNSALK TSRRMTMD

UniProtKB: Large ribosomal subunit protein mL62

+
Macromolecule #44: Large ribosomal subunit protein mL64

MacromoleculeName: Large ribosomal subunit protein mL64 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 25.865463 KDa
SequenceString: MAALAMRSGY LLRLSVALGP RSRSYRAPPP PRRRPGPHSP DPENLLTPRW QLTPRYVAKQ FGRHGAISGV PPASLWPTPE QLRELEAEE QEWYPSLATM QESLRLQQQA LEARRQAREQ RIAECMAKMP QMIENWRKQK RERWEKIQAD KERRARLQAE A QERLGYHV ...String:
MAALAMRSGY LLRLSVALGP RSRSYRAPPP PRRRPGPHSP DPENLLTPRW QLTPRYVAKQ FGRHGAISGV PPASLWPTPE QLRELEAEE QEWYPSLATM QESLRLQQQA LEARRQAREQ RIAECMAKMP QMIENWRKQK RERWEKIQAD KERRARLQAE A QERLGYHV DPRSARFQEL LQDLDKQQRK RLKEERQRQK KEARIAAMAS AEAQDSAVSG EPSS

UniProtKB: Large ribosomal subunit protein mL64

+
Macromolecule #45: Large ribosomal subunit protein mL66

MacromoleculeName: Large ribosomal subunit protein mL66 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 22.36351 KDa
SequenceString: MAALRRLVSG CGRQLQAFLA GPAATGWLWL PARGLREVVK IQEGKTTVIE GRITETPKAT PDPPNPSGQC PICRWNLKHK YTYEDVLLL SQFIRPYGGM LPRRVTGLCR EEHRKIEECV KMAHRAGLLP NHRPQLPEGC LPKDKPKLNR YLTRWAPKSV K PIYKKGHR ...String:
MAALRRLVSG CGRQLQAFLA GPAATGWLWL PARGLREVVK IQEGKTTVIE GRITETPKAT PDPPNPSGQC PICRWNLKHK YTYEDVLLL SQFIRPYGGM LPRRVTGLCR EEHRKIEECV KMAHRAGLLP NHRPQLPEGC LPKDKPKLNR YLTRWAPKSV K PIYKKGHR WNKVGMAVGS PLLKDNVCYS RRPLKMMH

UniProtKB: Large ribosomal subunit protein mL66

+
Macromolecule #46: Large ribosomal subunit protein mL65

MacromoleculeName: Large ribosomal subunit protein mL65 / type: protein_or_peptide / ID: 46 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 50.005184 KDa
SequenceString: MAAARYWKLV PRGRGLSQNA AAKASATAPE VRDLEVVATP VARYPPIVAS MTADSKAARQ RRVQRWQATV HAAPSVDEKI RILTKMQFK KYVVHPQISA LNADRWYQSF TKTVFVSGLP PAPALSPPPP SLDLAALRAA VCDCILQEQV YVRRRRPRSL F DRRQALAS ...String:
MAAARYWKLV PRGRGLSQNA AAKASATAPE VRDLEVVATP VARYPPIVAS MTADSKAARQ RRVQRWQATV HAAPSVDEKI RILTKMQFK KYVVHPQISA LNADRWYQSF TKTVFVSGLP PAPALSPPPP SLDLAALRAA VCDCILQEQV YVRRRRPRSL F DRRQALAS SILDQVVRTL VNLLAPLNPV LSTAALDCKR SVDFYWLRGE ERIPAGHRKG HIDALRYQIN DKPHNQIRIS KQ LPEFVPL DYSIPTEIPV MKCKPDKLPL FRRQYENSIF TGSKTADPCC YGHTQFHLIP DRLKRERLIR QNQAEQVEAV FRA NAIASL FAWTGAQAMY QGFWSEADVT RPFVSQAVIT DGKYFSFFCY QLNTLALTVQ ADQNNPRKNL CWGSQSQPLY ETVE DNDVK GFDDGTLLQI VHFLLNKPRE DGAQLLASQE KELDLGP

UniProtKB: Large ribosomal subunit protein mL65

+
Macromolecule #47: Mitochondrial assembly of ribosomal large subunit protein 1

MacromoleculeName: Mitochondrial assembly of ribosomal large subunit protein 1
type: protein_or_peptide / ID: 47 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 26.055053 KDa
SequenceString: MGPGWSPARR LWPLLWRRAV FQRAGPAMAS VPWLPRLAER WLPARPATCL TPSLTRGLHH GPQPEERTAG DARLQPGPAD HIGAKFDID MLVSLLRQEN ARDICVIQVP PEMRYTDYFV IGSGTSTRHL HAMVHYLVKM YKHLKCRSDP YVKIEGKDAD D WLCVDFGS ...String:
MGPGWSPARR LWPLLWRRAV FQRAGPAMAS VPWLPRLAER WLPARPATCL TPSLTRGLHH GPQPEERTAG DARLQPGPAD HIGAKFDID MLVSLLRQEN ARDICVIQVP PEMRYTDYFV IGSGTSTRHL HAMVHYLVKM YKHLKCRSDP YVKIEGKDAD D WLCVDFGS MVIHLMLPET RETYELEKLW TLRSFDDQLA QIAAETLPED FILGLEDDTS SLTPVEFKCK

UniProtKB: Mitochondrial assembly of ribosomal large subunit protein 1

+
Macromolecule #48: Predicted gene, 55359

MacromoleculeName: Predicted gene, 55359 / type: protein_or_peptide / ID: 48 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 8.444846 KDa
SequenceString:
MAPWSREAVL CLYRALLRQG RELRYTDRDF YFASIRREFR KNQKLENLEA REKQLEKGLV FLHSKLGGLI

UniProtKB: Predicted gene, 55359

+
Macromolecule #49: Acyl carrier protein, mitochondrial

MacromoleculeName: Acyl carrier protein, mitochondrial / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 17.390289 KDa
SequenceString:
MASRVLCACV RRLPAAFAPL PRLPTLALAR PLSTTLCPEG IRRRPGALQS ALALAQVPGT VTHLCRQYSD APPLTLDGIK DRVLYVLKL YDKIDPEKLS VNSHFMKDLG LDSLDQVEII MAMEDEFGFE IPDIDAEKLM CPQEIVDYIA DKKDVYE

UniProtKB: Acyl carrier protein, mitochondrial

+
Macromolecule #50: Large ribosomal subunit protein mL37

MacromoleculeName: Large ribosomal subunit protein mL37 / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 48.407668 KDa
SequenceString: MALASGPALR ALAGSGRLGL GGYGTPKRGA YEWGVRSTRK PEPRPLDRVY EIPGLEPITY EGKKHFVPWL ARPIFPPWER GWNDPRFHR AAPIHEQTLY KEEPCYIFHQ RCRLLEGMKQ ALWLTKTKLI EGLPKKVLSL VDDPANHIEN QEQRVLDIIS H ARLWHSTE ...String:
MALASGPALR ALAGSGRLGL GGYGTPKRGA YEWGVRSTRK PEPRPLDRVY EIPGLEPITY EGKKHFVPWL ARPIFPPWER GWNDPRFHR AAPIHEQTLY KEEPCYIFHQ RCRLLEGMKQ ALWLTKTKLI EGLPKKVLSL VDDPANHIEN QEQRVLDIIS H ARLWHSTE DIPKRETYCP LIVDSLIQLC KSQILKHPSL ARRTSAQNCT LATTWNRESL LLQVRGTSST ILSAKDPLPV IA SREEVEA TRSHVLETFY PISPTIDLQE CHVYEVKDDT GFQEGYPYPH PHTLYFLEKA NLRPQRFLPE QLRAKMLLFA FAN ALAQAR LLYGNTAKVL EQPIVVQSVG TDGRVFQFLV LQLNTTDLAS SEGVKNLVWT DSDQLLYRHF WCRPVIKKKV VVEP VGPVD FQPETFRKFL ALYLHGVV

UniProtKB: Large ribosomal subunit protein mL37

+
Macromolecule #51: Large ribosomal subunit protein mL40

MacromoleculeName: Large ribosomal subunit protein mL40 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 24.347057 KDa
SequenceString: MATGVMLCAA RALRPRSWIP GTCQAHVRHT HQRASLLAFW DLIPMRAEPL RKKKKVDPRK DQAAKDRLKK RIRKLEKASQ ELIPIEDFI TPVRFLDKSR QRPQEEHSPE ESERRALLLK RWALFKQQEH EMERDAIRSM LEAQQEALEE LKLESAELYA E AIKRDTSL ...String:
MATGVMLCAA RALRPRSWIP GTCQAHVRHT HQRASLLAFW DLIPMRAEPL RKKKKVDPRK DQAAKDRLKK RIRKLEKASQ ELIPIEDFI TPVRFLDKSR QRPQEEHSPE ESERRALLLK RWALFKQQEH EMERDAIRSM LEAQQEALEE LKLESAELYA E AIKRDTSL FPFEKEGPHY TPPISNYQAP EGRYNDITKV YTQVEFKR

UniProtKB: Large ribosomal subunit protein mL40

+
Macromolecule #52: Large ribosomal subunit protein mL41

MacromoleculeName: Large ribosomal subunit protein mL41 / type: protein_or_peptide / ID: 52 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 15.284592 KDa
SequenceString:
MGFLTAVTQG LVRGADRMSK WTSKRGPRTF TKSRGAKKTG IYTSDRKFVQ IKEMVPEFVV PDLTGFKLKP YVNYRAPAGI DTPLTAKAL FQETVAPAIE KDFKEGTFDA NNLEKYGFEP TQEGKLFQLY PKNFPR

UniProtKB: Large ribosomal subunit protein mL41

+
Macromolecule #53: Large ribosomal subunit protein mL42

MacromoleculeName: Large ribosomal subunit protein mL42 / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 16.521848 KDa
SequenceString:
MAAAVKWAIS NRTIWKHLLP IQNGALSSAC HKSTYSSLPD DYNCQVDLAL TADGRTIVCY HPSVDIPYEH TKPIPQPDLL HNNEETHEQ ILKAKLEVRK SKQLEQGPMI EQLSKVFYTT KHRWYPHGQY HNRRKKLNPP RDR

UniProtKB: Large ribosomal subunit protein mL42

+
Macromolecule #54: Large ribosomal subunit protein mL55

MacromoleculeName: Large ribosomal subunit protein mL55 / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 15.15264 KDa
SequenceString:
MPLAILLSLL RHCGVRAALP TPRHLHTSPW RADCSRASLT RLRRQAYARL YPVLLVKQDG STIHIRYREP RRMLAMPLDL DALSPEERR ARFRKREAQL QQKREEEPEV VDSFDTERYK QFWTKTKK

UniProtKB: Large ribosomal subunit protein mL55

+
Macromolecule #55: Mitochondrial ribosome-associated GTPase 1

MacromoleculeName: Mitochondrial ribosome-associated GTPase 1 / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 36.732039 KDa
SequenceString: MRLWPQAWGA VRGAWRECFP LQGHDVARWF PGHMAKGLKK MQSSLKSVDC VIEVHDARIP FSGRNPLFQE LLGLKPHLLV LNKMDLADL TEQQKIVQRL EEKGLSNVLF TNCVKDENIK QIVPKVMELI RCSYRYHRAE TPEYCIMVVG VPNVGKSSLI N SLRRQHLR ...String:
MRLWPQAWGA VRGAWRECFP LQGHDVARWF PGHMAKGLKK MQSSLKSVDC VIEVHDARIP FSGRNPLFQE LLGLKPHLLV LNKMDLADL TEQQKIVQRL EEKGLSNVLF TNCVKDENIK QIVPKVMELI RCSYRYHRAE TPEYCIMVVG VPNVGKSSLI N SLRRQHLR TGKAARVGGE PGITRAVTSR IQVCERPLVF LLDTPGVLAP RIESVETGLK LALCGTVLDH LVGEETMADY LL YTLNRHG LFGYVQHYAL ASACDQIEWV LKNVAIKLRK TRKVKVLTGT GNVNVIQPDY AMAARDFLRT FRSGLLGQVM LDR DIIPAC

UniProtKB: Mitochondrial ribosome-associated GTPase 1

+
Macromolecule #56: Large ribosomal subunit protein mL54

MacromoleculeName: Large ribosomal subunit protein mL54 / type: protein_or_peptide / ID: 56 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 15.450881 KDa
SequenceString:
MAAAHLLRAS RVWARWHPRA LPVLRRPGGF SIREYAKKPV GKGGKGGVAA EALKDPEVCT DPTQLTTHAM GVNIYKEGQD VALKADSEY PTWLFQVNLG PPKKLEELEP ESREYWRLLR KQNIWRHNRL SKNKKL

UniProtKB: Large ribosomal subunit protein mL54

+
Macromolecule #57: Transcription termination factor 4, mitochondrial

MacromoleculeName: Transcription termination factor 4, mitochondrial / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 40.30618 KDa
SequenceString: MASLGRQVPE WHRLLALSWA CLVRQTPHLR EQKQMSPSLS CKLTTVPGRG SFQEFSSITP QKYMQEPENR TRLVQCLHEE QKPCVDPES LEPEKVIRSL QDMGFAEAHI HSLFSIQPSV HPQQLLGIVS ELLLLGLNPE PVFNALKKNP QLLKLSSMQM K RRSSYLRK ...String:
MASLGRQVPE WHRLLALSWA CLVRQTPHLR EQKQMSPSLS CKLTTVPGRG SFQEFSSITP QKYMQEPENR TRLVQCLHEE QKPCVDPES LEPEKVIRSL QDMGFAEAHI HSLFSIQPSV HPQQLLGIVS ELLLLGLNPE PVFNALKKNP QLLKLSSMQM K RRSSYLRK LGLGEGKLKR VLSVCPEVFT MHQRDIDRVV KVLREKCLFT AQHITDVLHR CPTVLQEDPN ELEYKFQYAY FR MGLTHLD IVRTNFLQYS ITKIKQRHIY LERLGRYQTP DKKGQTQIPN PSLRNILRVS EAEFLARTAC SSVEEFQVFK KLL DQEEEE ESESHASEEE EEEEEEEELL

UniProtKB: Transcription termination factor 4, mitochondrial

+
Macromolecule #58: GTP-binding protein 10

MacromoleculeName: GTP-binding protein 10 / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Mus musculus (house mouse)
Molecular weightTheoretical: 40.200605 KDa
SequenceString: MVRCGCALLR KYGNFIDNLR IFTKGGSGGM GYPRLGGEGG RGGDVWVVAH KNMTLKQLKN KYPQKRFVAG GGANSRVSAL QGSKGKDCE VPAPVGISVT DENGQVLGEL NKEEDRVLVA KGGLGGKLHT NFLPLKGQKR IVHLDLKVIA DVGLVGFPNA G KSSLLSRV ...String:
MVRCGCALLR KYGNFIDNLR IFTKGGSGGM GYPRLGGEGG RGGDVWVVAH KNMTLKQLKN KYPQKRFVAG GGANSRVSAL QGSKGKDCE VPAPVGISVT DENGQVLGEL NKEEDRVLVA KGGLGGKLHT NFLPLKGQKR IVHLDLKVIA DVGLVGFPNA G KSSLLSRV SHATPVIADY AFTTLRPELG KIMYNDFKQI SVADLPGLIE GAHMNKGMGH KFLKHLERTR QLLFVVDISG FQ LSSVTPY RTAFETIILL TKELELYKEE LQTKPALLAI NKMDLPDAQV KLQELMKQLL SPEDFLHLFE TKMIPEKALE FQH IVPIST VTGEGIAELK SCIRKALDEQ DGKESDAHRS KQLLNLQSSS

UniProtKB: GTP-binding protein 10

+
Macromolecule #59: MAGNESIUM ION

MacromoleculeName: MAGNESIUM ION / type: ligand / ID: 59 / Number of copies: 95 / Formula: MG
Molecular weightTheoretical: 24.305 Da

+
Macromolecule #60: ZINC ION

MacromoleculeName: ZINC ION / type: ligand / ID: 60 / Number of copies: 2 / Formula: ZN
Molecular weightTheoretical: 65.409 Da

+
Macromolecule #61: FE2/S2 (INORGANIC) CLUSTER

MacromoleculeName: FE2/S2 (INORGANIC) CLUSTER / type: ligand / ID: 61 / Number of copies: 1 / Formula: FES
Molecular weightTheoretical: 175.82 Da
Chemical component information

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

+
Macromolecule #62: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

MacromoleculeName: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / type: ligand / ID: 62 / Number of copies: 2 / Formula: GNP
Molecular weightTheoretical: 522.196 Da
Chemical component information

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

-
Experimental details

-
Structure determination

Methodcryo EM
Processingsingle particle reconstruction
Aggregation stateparticle

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Sample preparation

BufferpH: 7.5
VitrificationCryogen name: ETHANE

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Electron microscopy

MicroscopeTFS KRIOS
Image recordingFilm or detector model: GATAN K3 (6k x 4k) / Average electron dose: 40.0 e/Å2
Electron beamAcceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
Electron opticsIllumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELD / Nominal defocus max: 2.0 µm / Nominal defocus min: 0.4 µm
Experimental equipment
Model: Titan Krios / Image courtesy: FEI Company

+
Image processing

CTF correctionType: PHASE FLIPPING AND AMPLITUDE CORRECTION
Startup modelType of model: PDB ENTRY
PDB model - PDB ID:

7o9m


Details: GTPBP7 was taken from PDB 7PD3
Final reconstructionResolution.type: BY AUTHOR / Resolution: 3.62 Å / Resolution method: FSC 0.143 CUT-OFF / Number images used: 6503
Initial angle assignmentType: MAXIMUM LIKELIHOOD
Final angle assignmentType: MAXIMUM LIKELIHOOD

+
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