EMDB-34359: PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state

基本情報

登録情報

データベース: EMDB / ID: EMD-34359

• タイトル: PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
• マップデータ: PIC-Mediator in complex with plus 1 nucleosome (T40N) in MH-binding state

試料

• 複合体: PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
  • DNA: x 4種
  • タンパク質・ペプチド: x 73種
• リガンド: x 3種

• キーワード: PIC / Mediator / transcription initiation / +1 nucleosome / TRANSCRIPTION

機能・相同性

分子機能:

positive regulation of mediator complex assembly / positive regulation of T cell extravasation / negative regulation of smooth muscle cell differentiation / spermine transport / negative regulation of MHC class I biosynthetic process / MMXD complex / core TFIIH complex portion of holo TFIIH complex / SAGA complex assembly / lateral mesodermal cell differentiation / enucleate erythrocyte development / regulation of RNA biosynthetic process / DNA-templated transcription open complex formation / allantois development / positive regulation of type II interferon-mediated signaling pathway / pre-snoRNP complex / positive regulation of androgen receptor activity / Cytosolic iron-sulfur cluster assembly / androgen biosynthetic process / positive regulation of G0 to G1 transition / TFIIH-class transcription factor complex binding / histone H4K16ac reader activity / retinal pigment epithelium development / central nervous system myelin formation / negative regulation of protein autoubiquitination / G0 to G1 transition / positive regulation of core promoter binding / mammary gland branching involved in thelarche / thyroid hormone receptor signaling pathway / transcription factor TFTC complex / RNA polymerase II core complex assembly / positive regulation of mitotic recombination / hair cell differentiation / negative regulation of MHC class II biosynthetic process / hair follicle maturation / RNA polymerase I general transcription initiation factor activity / regulation of cell cycle G1/S phase transition / ventricular system development / nucleotide-excision repair factor 3 complex / core mediator complex / transcription factor TFIIE complex / RNA polymerase transcription factor SL1 complex / meiotic sister chromatid cohesion / nucleotide-excision repair, preincision complex assembly / phosphatase activator activity / snRNA transcription by RNA polymerase II / regulation of vitamin D receptor signaling pathway / SLIK (SAGA-like) complex / CAK-ERCC2 complex / transcription factor TFIIK complex / RNA polymerase III general transcription initiation factor activity / TFIIF-class transcription factor complex binding / UV protection / transcriptional start site selection at RNA polymerase II promoter / RNA polymerase I core promoter sequence-specific DNA binding / nuclear retinoic acid receptor binding / hepatocyte differentiation / embryonic cleavage / transcription factor TFIIF complex / DNA 5'-3' helicase / positive regulation of response to cytokine stimulus / ventricular trabecula myocardium morphogenesis / Formation of RNA Pol II elongation complex / Formation of the Early Elongation Complex / Transcriptional regulation by small RNAs / RNA Polymerase II Pre-transcription Events / TP53 Regulates Transcription of DNA Repair Genes / FGFR2 alternative splicing / RNA polymerase II transcribes snRNA genes / mRNA Capping / mRNA Splicing - Minor Pathway / Processing of Capped Intron-Containing Pre-mRNA / RNA Polymerase II Promoter Escape / RNA Polymerase II Transcription Pre-Initiation And Promoter Opening / RNA Polymerase II Transcription Initiation / RNA Polymerase II Transcription Elongation / RNA Polymerase II Transcription Initiation And Promoter Clearance / RNA Pol II CTD phosphorylation and interaction with CE / Estrogen-dependent gene expression / Formation of TC-NER Pre-Incision Complex / Dual incision in TC-NER / Gap-filling DNA repair synthesis and ligation in TC-NER / mRNA Splicing - Major Pathway / maintenance of protein location in nucleus / mediator complex / RNA polymerase II CTD heptapeptide repeat Y1 kinase activity / RNA polymerase II CTD heptapeptide repeat S2 kinase activity / RNA polymerase II CTD heptapeptide repeat T4 kinase activity / RNA polymerase II CTD heptapeptide repeat S5 kinase activity / RNA polymerase II CTD heptapeptide repeat S7 kinase activity / positive regulation of keratinocyte differentiation / RNA Polymerase III Transcription Initiation From Type 1 Promoter / RNA Polymerase III Transcription Initiation From Type 2 Promoter / RNA Polymerase III Transcription Initiation From Type 3 Promoter / thyroid hormone generation / Generic Transcription Pathway / transcription factor TFIIA complex / peroxisome proliferator activated receptor binding / G protein-coupled receptor internalization / female germ cell nucleus / adult heart development

ドメイン・相同性:

Mediator complex subunit 26, C-terminal domain / Mediator complex subunit 26, middle domain / Mediator of RNA polymerase II transcription subunit 26 / Mediator complex subunit 26 C-terminal / Mediator complex subunit 26 middle domain / Mediator complex, subunit Med25, PTOV domain / Mediator complex, subunit Med25, synapsin 1 / Mediator complex subunit 25, PTOV domain superfamily / Mediator complex subunit 25 PTOV activation and synapsin 2 / Mediator complex subunit 25 synapsin 1 / Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain / Mediator complex subunit 25 von Willebrand factor type A / Mediator complex, subunit Med19, metazoa / Mediator of RNA pol II transcription subunit 19 / Mediator complex, subunit Med29, metazoa / Mediator complex, subunit Med24, / : / Mediator complex subunit 24 N-terminal / Mediator complex subunit 29 / Mediator complex subunit 16, central helical bridge / Mediator of RNA polymerase II transcription subunit 15 / : / : / ARC105/Med15 mediator subunit N-terminal KIX domain / ARC105/Med15 mediator subunit central domain / ARC105/Med15 mediator subunit C-terminal domain / Mediator complex, subunit Med6, metazoa/plant / Mediator complex, subunit Med30, metazoa / Mediator complex, subunit Med28 / Mediator of RNA polymerase II transcription subunit 9, metazoan / : / : / : / Mediator complex subunit 30 / Mediator complex subunit 28 / Mediator of RNA polymerase II transcription subunit 14, RM2 / Mediator of RNA polymerase II transcription subunit 14, RM8 / Mediator of RNA polymerase II transcription subunit 14, RM6 / Mediator complex, subunit Med23 / Mediator complex subunit 23 / Mediator complex, subunit Med27 / Mediator complex subunit 27 / : / Mediator complex subunit 16, C-terminal / Mediator complex, subunit Med16 / : / Mediator complex subunit 16, N-terminal / : / Mediator complex, subunit Med10 / Transcription factor subunit Med10 of Mediator complex / Mediator of RNA polymerase II transcription subunit 9 / RNA polymerase II transcription mediator complex subunit 9 / Mediator complex, subunit Med4 / Vitamin-D-receptor interacting Mediator subunit 4 / Mediator complex, subunit Med31 / Mediator complex, subunit Med21 / Mediator of RNA polymerase II, subunit Med31 superfamily / SOH1 / Subunit 21 of Mediator complex / Mediator complex, subunit Med7 / Mediator complex, subunit Med7/Med21-like / Mediator complex, subunit Med7 superfmaily / : / MED7 protein / Mediator complex, subunit Med20 / Mediator complex, subunit Med14 / TATA-binding related factor (TRF) of subunit 20 of Mediator complex / Mediator complex subunit MED14 / Soluble quinoprotein glucose/sorbosone dehydrogenase / Mediator complex, subunit Med6 / Mediator complex, subunit Med17 / Mediator complex, subunit Med6 superfamily / MED6 mediator sub complex component / Subunit 17 of Mediator complex / Mediator of RNA polymerase II transcription subunit 22 / Mediator complex, subunit Med8, fungi/metazoa / Mediator complex, subunit Med11 / Surfeit locus protein 5 subunit 22 of Mediator complex / Mediator of RNA polymerase II transcription complex subunit 8 / Mediator complex protein / Mediator complex, subunit Med18 / Med18 protein / TAFII28-like protein domain / Transcription initiation factor TFIID subunit 11-like / hTAFII28-like protein conserved region / TAFII55 protein, conserved region / Transcription initiation factor TFIID subunit 7 / TAFII55 protein conserved region / TAFII55 protein conserved region / Transcription initiation factor TFIID subunit 2 / Transcription initiation factor TFIID subunit 8 / Transcription factor TFIID complex subunit 8 C-term / Transcription factor TFIID, subunit 8, C-terminal / Transcription initiation factor TFIID component TAF4 / Transcription initiation factor TFIID component TAF4 family / Transcription initiation factor TFIID component TAF4, C-terminal / Transcription initiation factor IID, subunit 13 / Transcription initiation factor IID, 18kD subunit / TAFH/NHR1 domain superfamily / NHR1 homology to TAF

構成要素:

Histone H3 / DNA-directed RNA polymerase II subunit RPB4 / DNA-directed RNA polymerases I, II, and III subunit RPABC5 / RNA polymerase II, I and III subunit K / DNA-directed RNA polymerase subunit beta / DNA-directed RNA polymerase II subunit RPB11-a / DNA-directed RNA polymerases I, II, and III subunit RPABC3 / DNA-directed RNA polymerases I, II, and III subunit RPABC2 / DNA-directed RNA polymerase subunit / DNA-directed RNA polymerase II subunit E / DNA-directed RNA polymerase subunit / Histone H2B / Mediator of RNA polymerase II transcription subunit 19 / DNA-directed RNA polymerase II subunit RPB3 / Transcription initiation factor TFIID subunit 4 / Mediator of RNA polymerase II transcription subunit 7 / Mediator of RNA polymerase II transcription subunit 14 / Mediator of RNA polymerase II transcription subunit 24 / Mediator of RNA polymerase II transcription subunit 6 / Mediator of RNA polymerase II transcription subunit 26 / General transcription factor IIF subunit 2 / General transcription and DNA repair factor IIH helicase subunit XPD / General transcription and DNA repair factor IIH helicase/translocase subunit XPB / TATA-box-binding protein / Transcription initiation factor TFIID subunit 1 / General transcription factor IIE subunit 1 / Transcription initiation factor IIE subunit beta / General transcription factor IIH subunit 1 / General transcription factor IIF subunit 1 / Transcription initiation factor TFIID subunit 6 / Cyclin-dependent kinase 7 / Cyclin-H / CDK-activating kinase assembly factor MAT1 / Transcription initiation factor IIA subunit 1 / Transcription initiation factor IIA subunit 2 / DNA-directed RNA polymerase II subunit RPB9 / Histone H4 / Transcription initiation factor IIB / Transcription initiation factor TFIID subunit 10 / Mediator of RNA polymerase II transcription subunit 21 / General transcription factor IIH subunit 2 / General transcription factor IIH subunit 3 / Mediator of RNA polymerase II transcription subunit 22 / Transcription initiation factor TFIID subunit 5 / Transcription initiation factor TFIID subunit 13 / Transcription initiation factor TFIID subunit 11 / Transcription initiation factor TFIID subunit 7 / Mediator of RNA polymerase II transcription subunit 1 / Transcription initiation factor TFIID subunit 12 / Transcription initiation factor TFIID subunit 9 / Transcription initiation factor TFIID subunit 3 / Transcription initiation factor TFIID subunit 2 / Mediator of RNA polymerase II transcription subunit 27 / General transcription factor IIH subunit 5 / Mediator of RNA polymerase II transcription subunit 25 / Transcription initiation factor TFIID subunit 8 / General transcription factor IIH subunit 4 / Mediator of RNA polymerase II transcription subunit 8 / Mediator of RNA polymerase II transcription subunit 30 / Mediator of RNA polymerase II transcription subunit 15 / Mediator of RNA polymerase II transcription subunit 10 / Mediator of RNA polymerase II transcription subunit 18 / Mediator of RNA polymerase II transcription subunit 28 / Mediator of RNA polymerase II transcription subunit 20 / Mediator of RNA polymerase II transcription subunit 4 / Mediator of RNA polymerase II transcription subunit 17 / Mediator of RNA polymerase II transcription subunit 9 / Mediator of RNA polymerase II transcription subunit 29 / Mediator of RNA polymerase II transcription subunit 11 / Mediator of RNA polymerase II transcription subunit 23 / Mediator of RNA polymerase II transcription subunit 16 / Mediator of RNA polymerase II transcription subunit 31

• 生物種: Sus scrofa (ブタ) / synthetic construct (人工物) / Homo sapiens (ヒト) / Xenopus laevis (アフリカツメガエル)
• 手法: 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 5.04 Å
• データ登録者: Chen X / Wang X / Liu W / Ren Y / Qu X / Li J / Yin X / Xu Y

資金援助

1件

Organization	Grant number	国
Not funded

• 引用: ジャーナル: Science / 年: 2022; タイトル: Structures of +1 nucleosome-bound PIC-Mediator complex.; 著者: Xizi Chen / Xinxin Wang / Weida Liu / Yulei Ren / Xuechun Qu / Jiabei Li / Xiaotong Yin / Yanhui Xu / ; 要旨: RNA polymerase II-mediated eukaryotic transcription starts with the assembly of the preinitiation complex (PIC) on core promoters. The +1 nucleosome is well positioned about 40 base pairs downstream of the transcription start site (TSS) and is commonly known as a barrier of transcription. The +1 nucleosome-bound PIC-Mediator structures show that PIC-Mediator prefers binding to T40N nucleosome located 40 base pairs downstream of TSS and contacts T50N but not the T70N nucleosome. The nucleosome facilitates the organization of PIC-Mediator on the promoter by binding TFIIH subunit p52 and Mediator subunits MED19 and MED26 and may contribute to transcription initiation. PIC-Mediator exhibits multiple nucleosome-binding patterns, supporting a structural role of the +1 nucleosome in the coordination of PIC-Mediator assembly. Our study reveals the molecular mechanism of PIC-Mediator organization on chromatin and underscores the significance of the +1 nucleosome in regulating transcription initiation.

履歴

登録	2022年9月21日	-
ヘッダ(付随情報) 公開	2022年11月2日	-
マップ公開	2022年11月2日	-
更新	2024年10月30日	-
現状	2024年10月30日	処理サイト: PDBj / 状態: 公開

マップ

• ファイル: ダウンロード / ファイル: emd_34359.map.gz / 形式: CCP4 / 大きさ: 282.6 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
• 注釈: PIC-Mediator in complex with plus 1 nucleosome (T40N) in MH-binding state
• ボクセルのサイズ: X=Y=Z: 1.334 Å

密度

表面レベル	登録者による: 0.156
最小 - 最大	-1.0336385 - 2.6775372
平均 (標準偏差)	0.015178453 (±0.07943054)

• 対称性: 空間群: 1

詳細

EMDB XML:

マップ形状	Axis order X Y Z Origin 0 0 0 サイズ 420 420 420 Spacing 420 420 420
セル	A=B=C: 560.27997 Å α=β=γ: 90.0 °

添付データ

追加マップ: PIC core of the T40N-bound PIC-Mediator

• ファイル: emd_34359_additional_1.map
• 注釈: PIC core of the T40N-bound PIC-Mediator

追加マップ: Mediator middle module and TFIIH CAK module of...

• ファイル: emd_34359_additional_10.map
• 注釈: Mediator middle module and TFIIH CAK module of the T40N-bound PIC-Mediator

追加マップ: Nucleosome of the PIC-Mediator in complex with plus...

• ファイル: emd_34359_additional_2.map
• 注釈: Nucleosome of the PIC-Mediator in complex with plus 1 nucleosome (T40N) in MH-binding state

追加マップ: Mediator of the T40N-bound PIC-Mediator

• ファイル: emd_34359_additional_3.map
• 注釈: Mediator of the T40N-bound PIC-Mediator

追加マップ: Nucleosome of the T40N-bound PIC-Mediator

• ファイル: emd_34359_additional_4.map
• 注釈: Nucleosome of the T40N-bound PIC-Mediator

追加マップ: Mediator tail module of the T40N-bound PIC-Mediator

• ファイル: emd_34359_additional_5.map
• 注釈: Mediator tail module of the T40N-bound PIC-Mediator

追加マップ: TFIIH of the T40N-bound PIC-Mediator

• ファイル: emd_34359_additional_6.map
• 注釈: TFIIH of the T40N-bound PIC-Mediator

追加マップ: TFIID of the T40N-bound PIC-Mediator

• ファイル: emd_34359_additional_7.map
• 注釈: TFIID of the T40N-bound PIC-Mediator

追加マップ: Mediator head module of the T40N-bound PIC-Mediator

• ファイル: emd_34359_additional_8.map
• 注釈: Mediator head module of the T40N-bound PIC-Mediator

追加マップ: Mediator middle module of the T40N-bound

• ファイル: emd_34359_additional_9.map
• 注釈: Mediator middle module of the T40N-bound

ハーフマップ: #2

• ファイル: emd_34359_half_map_1.map

ハーフマップ: #1

• ファイル: emd_34359_half_map_2.map

試料の構成要素

全体 : PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state

• 全体: 名称: PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state

要素

• 複合体: PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state
  • DNA: DNA (228-mer)
  • DNA: DNA (228-mer)
  • タンパク質・ペプチド: Transcription initiation factor IIB
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 1
  • タンパク質・ペプチド: General transcription factor IIE subunit 1
  • タンパク質・ペプチド: General transcription factor IIF subunit 1
  • タンパク質・ペプチド: General transcription and DNA repair factor IIH helicase subunit XPD
  • タンパク質・ペプチド: Histone H3
  • タンパク質・ペプチド: DNA-directed RNA polymerase subunit
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 2
  • タンパク質・ペプチド: Transcription initiation factor IIE subunit beta
  • タンパク質・ペプチド: General transcription factor IIF subunit 2
  • タンパク質・ペプチド: General transcription factor IIH subunit 1
  • タンパク質・ペプチド: Histone H4
  • タンパク質・ペプチド: DNA-directed RNA polymerase subunit beta
  • タンパク質・ペプチド: General transcription factor IIH subunit 4
  • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB3
  • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit E
  • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit F
  • タンパク質・ペプチド: DNA-directed RNA polymerases I, II, and III subunit RPABC3
  • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB9
  • タンパク質・ペプチド: DNA-directed RNA polymerases I, II, and III subunit RPABC5
  • タンパク質・ペプチド: RNA_pol_L_2 domain-containing protein
  • タンパク質・ペプチド: RPB12
  • タンパク質・ペプチド: TATA-box-binding protein
  • タンパク質・ペプチド: Transcription initiation factor IIA subunit 1
  • タンパク質・ペプチド: Transcription initiation factor IIA subunit 2
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 3
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 4
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 5
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 6
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 9
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 10
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 11
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 12
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 13
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 7
  • タンパク質・ペプチド: Transcription initiation factor TFIID subunit 8
  • タンパク質・ペプチド: CDK-activating kinase assembly factor MAT1
  • タンパク質・ペプチド: General transcription factor IIH subunit 3
  • タンパク質・ペプチド: General transcription factor IIH subunit 2
  • タンパク質・ペプチド: General transcription and DNA repair factor IIH helicase subunit XPB
  • タンパク質・ペプチド: General transcription factor IIH subunit 5
  • タンパク質・ペプチド: Cyclin-dependent kinase 7
  • タンパク質・ペプチド: Cyclin-H
  • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB4
  • タンパク質・ペプチド: DNA-directed RNA polymerase II subunit RPB7
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 7
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 10
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 14
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 19
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 21
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 1
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 4
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 6
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 9
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 31
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 17
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 26
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 29
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 27
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 28
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 30
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 15
  • タンパク質・ペプチド: Isoform 2 of Mediator of RNA polymerase II transcription subunit 8
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 11
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 18
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 20
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 22
  • タンパク質・ペプチド: Isoform 2 of Mediator of RNA polymerase II transcription subunit 16
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 23
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 24
  • タンパク質・ペプチド: Mediator of RNA polymerase II transcription subunit 25
  • タンパク質・ペプチド: HISTONE H2A.Z
  • タンパク質・ペプチド: Histone H2B
  • DNA: DNA (162-mer)
  • DNA: DNA (162-mer)
• リガンド: ZINC ION
• リガンド: IRON/SULFUR CLUSTER
• リガンド: MAGNESIUM ION

超分子 #1: PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state

• 超分子: 名称: PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state; タイプ: complex / ID: 1 / 親要素: 0 / 含まれる分子: #1-#77
• 由来(天然): 生物種: Sus scrofa (ブタ)

分子 #1: DNA (228-mer)

• 分子: 名称: DNA (228-mer) / タイプ: dna / ID: 1 / コピー数: 1 / 分類: DNA
• 由来(天然): 生物種: synthetic construct (人工物)
• 分子量: 理論値: 70.328703 KDa

配列

文字列:

(DG)(DA)(DA)(DG)(DG)(DG)(DC)(DG)(DC)(DC) (DT)(DA)(DT)(DA)(DA)(DA)(DA)(DG)(DG)(DG) (DG)(DG)(DT)(DG)(DG)(DG)(DG)(DG)(DC) (DG)(DC)(DG)(DT)(DT)(DC)(DG)(DT)(DC)(DC) (DG) (DC)(DA)(DC)(DG)(DG)(DC)(DC)(DG) (DA)(DT)(DC)(DG)(DA)(DA)(DC)(DA)(DC)(DT) (DC)(DG) (DA)(DG)(DC)(DC)(DG)(DA)(DG) (DC)(DA)(DG)(DA)(DC)(DG)(DT)(DG)(DC)(DC) (DT)(DA)(DC) (DG)(DC)(DT)(DG)(DG)(DA) (DG)(DA)(DA)(DT)(DC)(DC)(DC)(DG)(DG)(DT) (DG)(DC)(DC)(DG) (DA)(DG)(DG)(DC)(DC) (DG)(DC)(DT)(DC)(DA)(DA)(DT)(DT)(DG)(DG) (DT)(DC)(DG)(DT)(DA) (DG)(DA)(DC)(DA) (DG)(DC)(DT)(DC)(DT)(DA)(DG)(DC)(DA)(DC) (DC)(DG)(DC)(DT)(DT)(DA) (DA)(DA)(DC) (DG)(DC)(DA)(DC)(DG)(DT)(DA)(DC)(DG)(DC) (DG)(DC)(DT)(DG)(DT)(DC)(DC) (DC)(DC) (DC)(DG)(DC)(DG)(DT)(DT)(DT)(DT)(DA)(DA) (DC)(DC)(DG)(DC)(DC)(DA)(DA)(DG) (DG) (DG)(DG)(DA)(DT)(DT)(DA)(DC)(DT)(DC)(DC) (DC)(DT)(DA)(DG)(DT)(DC)(DT)(DC)(DC) (DA)(DG)(DG)(DC)(DA)(DC)(DG)(DT)(DG)(DT) (DC)(DA)(DC)(DA)(DT)(DA)(DT)(DA)(DT)(DA) (DC)(DA)(DT)(DC)(DC)(DT)(DG)(DT)

分子 #2: DNA (228-mer)

• 分子: 名称: DNA (228-mer) / タイプ: dna / ID: 2 / コピー数: 1 / 分類: DNA
• 由来(天然): 生物種: synthetic construct (人工物)
• 分子量: 理論値: 70.483766 KDa

配列

文字列:

(DA)(DC)(DA)(DG)(DG)(DA)(DT)(DG)(DT)(DA) (DT)(DA)(DT)(DA)(DT)(DG)(DT)(DG)(DA)(DC) (DA)(DC)(DG)(DT)(DG)(DC)(DC)(DT)(DG) (DG)(DA)(DG)(DA)(DC)(DT)(DA)(DG)(DG)(DG) (DA) (DG)(DT)(DA)(DA)(DT)(DC)(DC)(DC) (DC)(DT)(DT)(DG)(DG)(DC)(DG)(DG)(DT)(DT) (DA)(DA) (DA)(DA)(DC)(DG)(DC)(DG)(DG) (DG)(DG)(DG)(DA)(DC)(DA)(DG)(DC)(DG)(DC) (DG)(DT)(DA) (DC)(DG)(DT)(DG)(DC)(DG) (DT)(DT)(DT)(DA)(DA)(DG)(DC)(DG)(DG)(DT) (DG)(DC)(DT)(DA) (DG)(DA)(DG)(DC)(DT) (DG)(DT)(DC)(DT)(DA)(DC)(DG)(DA)(DC)(DC) (DA)(DA)(DT)(DT)(DG) (DA)(DG)(DC)(DG) (DG)(DC)(DC)(DT)(DC)(DG)(DG)(DC)(DA)(DC) (DC)(DG)(DG)(DG)(DA)(DT) (DT)(DC)(DT) (DC)(DC)(DA)(DG)(DC)(DG)(DT)(DA)(DG)(DG) (DC)(DA)(DC)(DG)(DT)(DC)(DT) (DG)(DC) (DT)(DC)(DG)(DG)(DC)(DT)(DC)(DG)(DA)(DG) (DT)(DG)(DT)(DT)(DC)(DG)(DA)(DT) (DC) (DG)(DG)(DC)(DC)(DG)(DT)(DG)(DC)(DG)(DG) (DA)(DC)(DG)(DA)(DA)(DC)(DG)(DC)(DG) (DC)(DC)(DC)(DC)(DC)(DA)(DC)(DC)(DC)(DC) (DC)(DT)(DT)(DT)(DT)(DA)(DT)(DA)(DG)(DG) (DC)(DG)(DC)(DC)(DC)(DT)(DT)(DC)

分子 #76: DNA (162-mer)

• 分子: 名称: DNA (162-mer) / タイプ: dna / ID: 76 / コピー数: 1 / 分類: DNA
• 由来(天然): 生物種: synthetic construct (人工物)
• 分子量: 理論値: 46.802422 KDa

配列

文字列:

(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)(DC)(DC)(DC)(DC)(DC) (DC)(DC)

分子 #77: DNA (162-mer)

• 分子: 名称: DNA (162-mer) / タイプ: dna / ID: 77 / コピー数: 1 / 分類: DNA
• 由来(天然): 生物種: synthetic construct (人工物)
• 分子量: 理論値: 53.286477 KDa

配列

文字列:

(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)(DG)(DG)(DG)(DG)(DG) (DG)(DG)

分子 #3: Transcription initiation factor IIB

• 分子: 名称: Transcription initiation factor IIB / タイプ: protein_or_peptide / ID: 3 / コピー数: 1 / 光学異性体: LEVO / EC番号: histone acetyltransferase
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 34.877949 KDa
• 組換発現: 生物種: Escherichia coli (大腸菌)

配列

文字列:

MASTSRLDAL PRVTCPNHPD AILVEDYRAG DMICPECGLV VGDRVIDVGS EWRTFSNDKA TKDPSRVGDS QNPLLSDGDL STMIGKGTG AASFDEFGNS KYQNRRTMSS SDRAMMNAFK EITTMADRIN LPRNIVDRTN NLFKQVYEQK SLKGRANDAI A SACLYIAC RQEGVPRTFK EICAVSRISK KEIGRCFKLI LKALETSVDL ITTGDFMSRF CSNLCLPKQV QMAATHIARK AV ELDLVPG RSPISVAAAA IYMASQASAE KRTQKEIGDI AGVADVTIRQ SYRLIYPRAP DLFPTDFKFD TPVDKLPQL

UniProtKB: Transcription initiation factor IIB

分子 #4: Transcription initiation factor TFIID subunit 1

• 分子: 名称: Transcription initiation factor TFIID subunit 1 / タイプ: protein_or_peptide / ID: 4 / コピー数: 1 / 光学異性体: LEVO / EC番号: histone acetyltransferase
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 212.956172 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MGPGCDLLLR TAATITAAAI MSDTDSDEDS AGGGPFSLAG FLFGNINGAG QLEGESVLDD ECKKHLAGLG ALGLGSLITE LTANEELTG TDGALVNDEG WVRSTEDAVD YSDINEVAED ESRRYQQTMG SLQPLCHSDY DEDDYDADCE DIDCKLMPPP P PPPGPMKK DKDQDSITGE KVDFSSSSDS ESEMGPQEAT QAESEDGKLT LPLAGIMQHD ATKLLPSVTE LFPEFRPGKV LR FLRLFGP GKNVPSVWRS ARRKRKKKHR ELIQEEQIQE VECSVESEVS QKSLWNYDYA PPPPPEQCLS DDEITMMAPV ESK FSQSTG DIDKVTDTKP RVAEWRYGPA RLWYDMLGVP EDGSGFDYGF KLRKTEHEPV IKSRMIEEFR KLEENNGTDL LADE NFLMV TQLHWEDDII WDGEDVKHKG TKPQRASLAG WLPSSMTRNA MAYNVQQGFA ATLDDDKPWY SIFPIDNEDL VYGRW EDNI IWDAQAMPRL LEPPVLTLDP NDENLILEIP DEKEEATSNS PSKESKKESS LKKSRILLGK TGVIKEEPQQ NMSQPE VKD PWNLSNDEYY YPKQQGLRGT FGGNIIQHSI PAVELRQPFF PTHMGPIKLR QFHRPPLKKY SFGALSQPGP HSVQPLL KH IKKKAKMREQ ERQASGGGEM FFMRTPQDLT GKDGDLILAE YSEENGPLMM QVGMATKIKN YYKRKPGKDP GAPDCKYG E TVYCHTSPFL GSLHPGQLLQ AFENNLFRAP IYLHKMPETD FLIIRTRQGY YIRELVDIFV VGQQCPLFEV PGPNSKRAN THIRDFLQVF IYRLFWKSKD RPRRIRMEDI KKAFPSHSES SIRKRLKLCA DFKRTGMDSN WWVLKSDFRL PTEEEIRAMV SPEQCCAYY SMIAAEQRLK DAGYGEKSFF APEEENEEDF QMKIDDEVRT APWNTTRAFI AAMKGKCLLE VTGVADPTGC G EGFSYVKI PNKPTQQKDD KEPQPVKKTV TGTDADLRRL SLKNAKQLLR KFGVPEEEIK KLSRWEVIDV VRTMSTEQAR SG EGPMSKF ARGSRFSVAE HQERYKEECQ RIFDLQNKVL SSTEVLSTDT DSSSAEDSDF EEMGKNIENM LQNKKTSSQL SRE REEQER KELQRMLLAA GSAASGNNHR DDDTASVTSL NSSATGRCLK IYRTFRDEEG KEYVRCETVR KPAVIDAYVR IRTT KDEEF IRKFALFDEQ HREEMRKERR RIQEQLRRLK RNQEKEKLKG PPEKKPKKMK ERPDLKLKCG ACGAIGHMRT NKFCP LYYQ TNAPPSNPVA MTEEQEEELE KTVIHNDNEE LIKVEGTKIV LGKQLIESAD EVRRKSLVLK FPKQQLPPKK KRRVGT TVH CDYLNRPHKS IHRRRTDPMV TLSSILESII NDMRDLPNTY PFHTPVNAKV VKDYYKIITR PMDLQTLREN VRKRLYP SR EEFREHLELI VKNSATYNGP KHSLTQISQS MLDLCDEKLK EKEDKLARLE KAINPLLDDD DQVAFSFILD NIVTQKMM A VPDSWPFHHP VNKKFVPDYY KVIVNPMDLE TIRKNISKHK YQSRESFLDD VNLILANSVK YNGPESQYTK TAQEIVNVC YQTLTEYDEH LTQLEKDICT AKEAALEEAE LESLDPMTPG PYTPQPPDLY DTNTSLSMSR DASVFQDESN MSVLDIPSAT PEKQVTQEG EDGDGDLADE EEGTVQQPQA SVLYEDLLMS EGEDDEEDAG SDEEGDNPFS AIQLSESGSD SDVGSGGIRP K QPRMLQEN TRMDMENEES MMSYEGDGGE ASHGLEDSNI SYGSYEEPDP KSNTQDTSFS SIGGYEVSEE EEDEEEEEQR SG PSVLSQV HLSEDEEDSE DFHSIAGDSD LDSDE

UniProtKB: Transcription initiation factor TFIID subunit 1

分子 #5: General transcription factor IIE subunit 1

• 分子: 名称: General transcription factor IIE subunit 1 / タイプ: protein_or_peptide / ID: 5 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 49.516094 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MADPDVLTEV PAALKRLAKY VIRGFYGIEH ALALDILIRN SCVKEEDMLE LLKFDRKQLR SVLNNLKGDK FIKCRMRVET AADGKTTRH NYYFINYRTL VNVVKYKLDH MRRRIETDER DSTNRASFKC PVCSSTFTDL EANQLFDPMT GTFRCTFCHT E VEEDESAM PKKDARTLLA RFNEQIEPIY ALLRETEDVN LAYEILEPEP TEIPALKQSK DHAATTAGAA SLAGGHHREA WA TKGPSYE DLYTQNVVIN MDDQEDLHRA SLEGKSAKER PIWLRESTVQ GAYGSEDMKE GGIDMDAFQE REEGHAGPDD NEE VMRALL IHEKKTSSAM AGSVGAAAPV TAANGSDSES ETSESDDDSP PRPAAVAVHK REEDEEEDDE FEEVADDPIV MVAG RPFSY SEVSQRPELV AQMTPEEKEA YIAMGQRMFE DLFE

UniProtKB: General transcription factor IIE subunit 1

分子 #6: General transcription factor IIF subunit 1

• 分子: 名称: General transcription factor IIF subunit 1 / タイプ: protein_or_peptide / ID: 6 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 58.343578 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAALGPSSQN VTEYVVRVPK NTTKKYNIMA FNAADKVNFA TWNQARLERD LSNKKIYQEE EMPESGAGSE FNRKLREEAR RKKYGIVLK EFRPEDQPWL LRVNGKSGRK FKGIKKGGVT ENTSYYIFTQ CPDGAFEAFP VHNWYNFTPL ARHRTLTAEE A EEEWERRN KVLNHFSIMQ QRRLKDQDQD EDEEEKEKRG RRKASELRIH DLEDDLEMSS DASDASGEEG GRVPKAKKKA PL AKGGRKK KKKKGSDDEA FEDSDDGDFE GQEVDYMSDG SSSSQEEPES KAKAPQQEEG PKGVDEQSDS SEESEEEKPP EED KEEEEE KKAPTPQEKK RRKDSSEESD SSEESDIDSE ASSALFMAKK KTPPKRERKP SGGSSRGNSR PGTPSAEGGS TSST LRAAA SKLEQGKRVS EMPAAKRLRL DTGPQSLSGK STPQPPSGKT TPNSGDVQVT EDAVRRYLTR KPMTTKDLLK KFQTK KTGL SSEQTVNVLA QILKRLNPER KMINDKMHFS LKE

UniProtKB: General transcription factor IIF subunit 1

分子 #7: General transcription and DNA repair factor IIH helicase subunit XPD

• 分子: 名称: General transcription and DNA repair factor IIH helicase subunit XPD; タイプ: protein_or_peptide / ID: 7 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA helicase
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 87.021078 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MKLNVDGLLV YFPYDYIYPE QFSYMRELKR TLDAKGHGVL EMPSGTGKTV SLLALIMAYQ RAYPLEVTKL IYCSRTVPEI EKVIEELRK LLNFYEKQEG EKLPFLGLAL SSRKNLCIHP EVTPLRFGKD VDGKCHSLTA SYVRAQYQHD TSLPHCRFYE E FDAHGREV PLPAGIYNLD DLKALGRRQG WCPYFLARYS ILHANVVVYS YHYLLDPKIA DLVSKELARK AVVVFDEAHN ID NVCIDSM SVNLTRRTLD RCQGNLETLQ KTVLRIKETD EQRLRDEYRR LVEGLREASA ARETDAHLAN PVLPDEVLQE AVP GSIRTA EHFLGFLRRL LEYVKWRLRV QHVVQESPPA FLSGLAQRVC IQRKPLRFCA ERLRSLLHTL EITDLADFSP LTLL ANFAT LVSTYAKGFT IIIEPFDDRT PTIANPILHF SCMDASLAIK PVFERFQSVI ITSGTLSPLD IYPKILDFHP VTMAT FTMT LARVCLCPMI IGRGNDQVAI SSKFETREDI AVIRNYGNLL LEMSAVVPDG IVAFFTSYQY MESTVASWYE QGILEN IQR NKLLFIETQD GAETSVALEK YQEACENGRG AILLSVARGK VSEGIDFVHH YGRAVIMFGV PYVYTQSRIL KARLEYL RD QFQIRENDFL TFDAMRHAAQ CVGRAIRGKT DYGLMVFADK RFARGDKRGK LPRWIQEHLT DANLNLTVDE GVQVAKYF L RQMAQPFHRE DQLGLSLLSL EQLESEETLK RIEQIAQQL

UniProtKB: General transcription and DNA repair factor IIH helicase subunit XPD

分子 #8: Histone H3

• 分子: 名称: Histone H3 / タイプ: protein_or_peptide / ID: 8 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Xenopus laevis (アフリカツメガエル)
• 分子量: 理論値: 15.435126 KDa
• 組換発現: 生物種: Escherichia coli (大腸菌)

配列

文字列:

MARTKQTARK STGGKAPRKQ LATKAARKSA PATGGVKKPH RYRPGTVALR EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSSA VMALQEASEA YLVALFEDTN LCAIHAKRVT IMPKDIQLAR RIRGERA

UniProtKB: Histone H3

分子 #9: DNA-directed RNA polymerase subunit

• 分子: 名称: DNA-directed RNA polymerase subunit / タイプ: protein_or_peptide / ID: 9 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA-directed RNA polymerase
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 217.450078 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MHGGGPPSGD SACPLRTIKR VQFGVLSPDE LKRMSVTEGG IKYPETTEGG RPKLGGLMDP RQGVIERTGR CQTCAGNMTE CPGHFGHIE LAKPVFHVGF LVKTMKVLRC VCFFCSKLLV DSNNPKIKDI LAKSKGQPKK RLTHVYDLCK GKNICEGGEE M DNKFGVEQ PEGDEDLTKE KGHGGCGRYQ PRIRRSGLEL YAEWKHVNED SQEKKILLSP ERVHEIFKRI SDEECFVLGM EP RYARPEW MIVTVLPVPP LSVRPAVVMQ GSARNQDDLT HKLADIVKIN NQLRRNEQNG AAAHVIAEDV KLLQFHVATM VDN ELPGLP RAMQKSGRPL KSLKQRLKGK EGRVRGNLMG KRVDFSARTV ITPDPNLSID QVGVPRSIAA NMTFAEIVTP FNID RLQEL VRRGNSQYPG AKYIIRDNGD RIDLRFHPKP SDLHLQTGYK VERHMCDGDI VIFNRQPTLH KMSMMGHRVR ILPWS TFRL NLSVTTPYNA DFDGDEMNLH LPQSLETRAE IQELAMVPRM IVTPQSNRPV MGIVQDTLTA VRKFTKRDVF LERGEV MNL LMFLSTWDGK VPQPAILKPR PLWTGKQIFS LIIPGHINCI RTHSTHPDDE DSGPYKHISP GDTKVVVENG ELIMGIL CK KSLGTSAGSL VHISYLEMGH DITRLFYSNI QTVINNWLLI EGHTIGIGDS IADSKTYQDI QNTIKKAKQD VIEVIEKA H NNELEPTPGN TLRQTFENQV NRILNDARDK TGSSAQKSLS EYNNFKSMVV SGAKGSKINI SQVIAVVGQQ NVEGKRIPF GFKHRTLPHF IKDDYGPESR GFVENSYLAG LTPTEFFFHA MGGREGLIDT AVKTAETGYI QRRLIKSMES VMVKYDATVR NSINQVVQL RYGEDGLAGE SVEFQNLATL KPSNKAFEKK FRFDYTNERA LRRTLQEDLV KDVLSNAHIQ NELEREFERM R EDREVLRV IFPTGDSKVV LPCNLLRMIW NAQKIFHINP RLPSDLHPIK VVEGVKELSK KLVIVNGDDP LSRQAQENAT LL FNIHLRS TLCSRRMAEE FRLSGEAFDW LLGEIESKFN QAIAHPGEMV GALAAQSLGE PATQMTLNTF HYAGVSAKNV TLG VPRLKE LINISKKPKT PSLTVFLLGQ SARDAERAKD ILCRLEHTTL RKVTANTAIY YDPNPQSTVV AEDQEWVNVY YEMP DFDVA RISPWLLRVE LDRKHMTDRK LTMEQIAEKI NAGFGDDLNC IFNDDNAEKL VLRIRIMNSD ENKMQEEEEV VDKMD DDVF LRCIESNMLT DMTLQGIEQI SKVYMHLPQT DNKKKIIITE DGEFKALQEW ILETDGVSLM RVLSEKDVDP VRTTSN DIV EIFTVLGIEA VRKALERELY HVISFDGSYV NYRHLALLCD TMTCRGHLMA ITRHGVNRQD TGPLMKCSFE ETVDVLM EA AAHGESDPMK GVSENIMLGQ LAPAGTGCFD LLLDAEKCKY GMEIPTNIPG LGAAGPTGMF FGSAPSPMGG ISPAMTPW N QGATPAYGAW SPSVGSGMTP GAAGFSPSAA SDASGFSPGY SPAWSPTPGS PGSPGPSSPY IPSPGGAMSP SYSPTSPAY EPRSPGGYTP QSPSYSPTSP SYSPTSPSYS PTSPNYSPTS PSYSPTSPSY SPTSPSYSPT SPSYSPTSPS YSPTSPSYSP TSPSYSPTS PSYSPTSPSY SPTSPSYSPT SPSYSPTSPS YSPTSPSYSP TSPSYSPTSP SYSPTSPNYS PTSPNYTPTS P SYSPTSPS YSPTSPNYTP TSPNYSPTSP SYSPTSPSYS PTSPSYSPSS PRYTPQSPTY TPSSPSYSPS SPSYSPTSPK YT PTSPSYS PSSPEYTPTS PKYSPTSPKY SPTSPKYSPT SPTYSPTTPK YSPTSPTYSP TSPVYTPTSP KYSPTSPTYS PTS PKYSPT SPTYSPTSPK GSTYSPTSPG YSPTSPTYSL TSPAISPDDS DEEN

UniProtKB: DNA-directed RNA polymerase subunit

分子 #10: Transcription initiation factor TFIID subunit 2

• 分子: 名称: Transcription initiation factor TFIID subunit 2 / タイプ: protein_or_peptide / ID: 10 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 137.159984 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MPLTGVEPAR MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGFVE LTIFPTVANL NRIKLNSKQC RIYRVRINDL EAAFIYNDP TLEVCHSESK QRNLNYFSNA YAAAVSAVDP DAGNGELCIK VPSELWKHVD ELKVLKIHIN FSLDQPKGGL H FVVPSVEG SMAERGAHVF SCGYQNSTRF WFPCVDSYSE LCTWKLEFTV DAAMVAVSNG DLVETVYTHD MRKKTFHYML TI PTAASNI SLAIGPFEIL VDPYMHEVTH FCLPQLLPLL KHTTSYLHEV FEFYEEILTC RYPYSCFKTV FIDEAYVEVA AYA SMSIFS TNLLHSAMII DETPLTRRCL AQSLAQQFFG CFISRMSWSD EWVLKGISGY IYGLWMKKTF GVNEYRHWIK EELD KIVAY ELKTGGVLLH PIFGGGKEKD NPASHLHFSI KHPHTLSWEY YSMFQCKAHL VMRLIENRIS MEFMLQVFNK LLSLA STAS SQKFQSHMWS QMLVSTSGFL KSISNVSGKD IQPLIKQWVD QSGVVKFYGS FAFNRKRNVL ELEIKQDYTS PGTQKY VGP LKVTVQELDG SFNHTLQIEE NSLKHDIPCH SKSRRNKKKK IPLMNGEEVD MDLSAMDADS PLLWIRIDPD MSVLRKV EF EQADFMWQYQ LRYERDVVAQ QESILALEKF PTPASRLALT DILEQEQCFY RVRMSACFCL AKIANSMVST WTGPPAMK S LFTRMFCCKS CPNIVKTNNF MSFQSYFLQK TMPVAMALLR DVHNLCPKEV LTFILDLIKY NDNRKNKFSD NYYRAEMID ALANSVTPAV SVNNEVRTLD NLNPDVRLIL EEITRFLNME KLLPSYRHTI TVSCLRAIRV LQKNGHVPSD PALFKSYAEY GHFVDIRIA ALEAVVDYTK VDRSYEELQW LLNMIQNDPV PYVRHKILNM LTKNPPFTKN MESPLCNEAL VDQLWKLMNS G TSHDWRLR CGAVDLYFTL FGLSRPSCLP LPELGLVLNL KEKKAVLNPT IIPESVAGNQ EAANNPSSHP QLVGFQNPFS SS QDEEEID MDTVHDSQAF ISHHLNMLER PSTPGLSKYR PASSRSALIP QHSAGCDSTP TTKPQWSLEL ARKGTGKEQA PLE MSMHPA ASAPLSVFTK ESTASKHSDH HHHHHHEHKK KKKKHKHKHK HKHKHDSKEK DKEPFTFSSP ASGRSIRSPS LSD

UniProtKB: Transcription initiation factor TFIID subunit 2

分子 #11: Transcription initiation factor IIE subunit beta

• 分子: 名称: Transcription initiation factor IIE subunit beta / タイプ: protein_or_peptide / ID: 11 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 33.106824 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MDPSLLRERE LFKKRALSTP VVEKRSASSE SSSSSSKKKK TKVEHGGSSG SKQNSDHSNG SFNLKALSGS SGYKFGVLAK IVNYMKTRH QRGDTHPLTL DEILDETQHL DIGLKQKQWL MTEALVNNPK IEVIDGKYAF KPKYNVRDKK ALLRLLDQHD Q RGLGGILL EDIEEALPNS QKAVKALGDQ ILFVNRPDKK KILFFNDKSC QFSVDEEFQK LWRSVTVDSM DEEKIEEYLK RQ GISSMQE SGPKKVAPIQ RRKKPASQKK RRFKTHNEHL AGVLKDYSDI TSSK

UniProtKB: Transcription initiation factor IIE subunit beta

分子 #12: General transcription factor IIF subunit 2

• 分子: 名称: General transcription factor IIF subunit 2 / タイプ: protein_or_peptide / ID: 12 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA helicase
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 28.427309 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAERGELDLT GAKQNTGVWL VKVPKYLSQQ WAKASGRGEV GKLRIAKTQG RTEVSFTLNE DLANIHDIGG KPASVSAPRE HPFVLQSVG GQTLTVFTES SSDKLSLEGI VVQRAECRPA ASENYMRLKR LQIEESSKPV RLSQQLDKVV TTNYKPVANH Q YNIEYERK KKEDGKRARA DKQHVLDMLF SAFEKHQYYN LKDLVDITKQ PVVYLKEILK EIGVQNVKGI HKNTWELKPE YR HYQGEEK SD

UniProtKB: General transcription factor IIF subunit 2

分子 #13: General transcription factor IIH subunit 1

• 分子: 名称: General transcription factor IIH subunit 1 / タイプ: protein_or_peptide / ID: 13 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 62.116492 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MATSSEEVLL IVKKVRQKKQ DGALYLMAER IAWAPEGKDR FTISHMYADI KCQKISPEGK AKIQLQLVLH AGDTTNFHFS NESTAVKER DAVKDLLQQL LPKFKRKANK ELEEKNRMLQ EDPVLFQLYK DLVVSQVISA EEFWANRLNV NATDSSSTSN H KQDVGISA AFLADVRPQT DGCNGLRYNL TSDIIESIFR TYPAVKMKYA ENVPHNMTEK EFWTRFFQSH YFHRDRLNTG SK DLFAECA KIDEKGLKTM VSLGVKNPLL DLTALEDKPL DEGYGISSVP SASNSKSIKE NSNAAIIKRF NHHSAMVLAA GLR KQEAQN EQTSEPSNMD GNSGDADCFQ PAVKRAKLQE SIEYEDLGKN NSVKTIALNL KKSDRYYHGP TPIQSLQYAT SQDI INSFQ SIRQEMEAYT PKLTQVLSSS AASSTITALS PGGALMQGGT QQAINQMVPN DIQSELKHLY VAVGELLRHF WSCFP VNTP FLEEKVVKMK SNLERFQVTK LCPFQEKIRR QYLSTNLVSH IEEMLQTAYN KLHTWQSRRL MKKT

UniProtKB: General transcription factor IIH subunit 1

分子 #14: Histone H4

• 分子: 名称: Histone H4 / タイプ: protein_or_peptide / ID: 14 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Xenopus laevis (アフリカツメガエル)
• 分子量: 理論値: 11.394426 KDa
• 組換発現: 生物種: Escherichia coli (大腸菌)

配列

文字列:

MSGRGKGGKG LGKGGAKRHR KVLRDNIQGI TKPAIRRLAR RGGVKRISGL IYEETRGVLK VFLENVIRDA VTYTEHAKRK TVTAMDVVY ALKRQGRTLY GFGG

UniProtKB: Histone H4

分子 #15: DNA-directed RNA polymerase subunit beta

• 分子: 名称: DNA-directed RNA polymerase subunit beta / タイプ: protein_or_peptide / ID: 15 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA-directed RNA polymerase
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 134.041422 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MYDADEDMQY DEDDDEITPD LWQEACWIVI SSYFDEKGLV RQQLDSFDEF IQMSVQRIVE DAPPIDLQAE AQHASGEVEE PPRYLLKFE QIYLSKPTHW ERDGAPSPMM PNEARLRNLT YSAPLYVDIT KTVIKEGEEQ LQTQHQKTFI GKIPIMLRST Y CLLNGLTD RDLCELNECP LDPGGYFIIN GSEKVLIAQE KMATNTVYVF AKKDSKYAYT GECRSCLENS SRPTSTIWVS ML ARGGQGA KKSAIGQRIV ATLPYIKQEV PIIIVFRALG FVSDRDILEH IIYDFEDPEM MEMVKPSLDE AFVIQEQNVA LNF IGSRGA KPGVTKEKRI KYAKEVLQKE MLPHVGVSDF CETKKAYFLG YMVHRLLLAA LGRRELDDRD HYGNKRLDLA GPLL AFLFR GMFKNLLKEV RIYAQKFIDR GKDFNLELAI KTRIISDGLK YSLATGNWGD QKKAHQARAG VSQVLNRLTF ASTLS HLRR LNSPIGRDGK LAKPRQLHNT LWGMVCPAET PEGHAVGLVK NLALMAYISV GSQPSPILEF LEEWSMENLE EISPAA IAD ATKIFVNGCW VGIHKDPEQL MNTLRKLRRQ MDIIVSEVSM IRDIREREIR IYTDAGRICR PLLIVEKQKL LLKKRHI DQ LKEREYNNYS WQDLVASGVV EYIDTLEEET VMLAMTPDDL QEKEVAYCST YTHCEIHPSM ILGVCASIIP FPDHNQSP R NTYQSAMGKQ AMGVYITNFH VRMDTLAHVL YYPQKPLVTT RSMEYLRFRE LPAGINSIVA IASYTGYNQE DSVIMNRSA VDRGFFRSVF YRSYKEQESK KGFDQEEVFE KPTRETCQGM RHAIYDKLDD DGLIAPGVRV SGDDVIIGKT VTLPENEDEL EGTNRRYTK RDCSTFLRTS ETGIVDQVMV TLNQEGYKFC KIRVRSVRIP QIGDKFASRH GQKGTCGIQY RQEDMPFTCE G ITPDIIIN PHAIPSRMTI GHLIECLQGK VSANKGEIGD ATPFNDAVNV QKISNLLSDY GYHLRGNEVL YNGFTGRKIT SQ IFIGPTY YQRLKHMVDD KIHSRARGPI QILNRQPMEG RSRDGGLRFG EMERDCQIAH GAAQFLRERL FEASDPYQVH VCN LCGIMA IANTRTHTYE CRGCRNKTQI SLVRMPYACK LLFQELMSMS IAPRMMSV

UniProtKB: DNA-directed RNA polymerase subunit beta

分子 #16: General transcription factor IIH subunit 4

• 分子: 名称: General transcription factor IIH subunit 4 / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 52.245156 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MESTPSRGLN RVHLQCRNLQ EFLGGLSPGV LDRLYGHPAT CLAVFRELPS LAKNWVMRML FLEQPLPQAA VALWVKKEFS KAQEESTGL LSGLRIWHTQ LLPGGLQGLI LNPIFRQNLR IALLGGGKAW SDDTSQLGPD KHARDVPSLD KYAEERWEVV L HFMVGSPS AAVSQDLAQL LSQAGLMKST EPGEPPCITS AGFQFLLLDT PAQLWYFMLQ YLQTAQSRGM DLVEILSFLF QL SFSTLGK DYSVEGMSDS LLNFLQHLRE FGLVFQRKRK SRRYYPTRLA INLSSGVSGA GGTVHQPGFI VVETNYRLYA YTE SELQIA LIALFSEMLY RFPNMVVAQV TRESVQQAIA SGITAQQIIH FLRTRAHPVM LKQTPVLPPT ITDQIRLWEL ERDR LRFTE GVLYNQFLSQ VDFELLLAHA RELGVLVFEN SAKRLMVVTP AGHSDVKRFW KRQKHSS

UniProtKB: General transcription factor IIH subunit 4

分子 #17: DNA-directed RNA polymerase II subunit RPB3

• 分子: 名称: DNA-directed RNA polymerase II subunit RPB3 / タイプ: protein_or_peptide / ID: 17 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 31.439074 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MPYANQPTVR ITELTDENVK FIIENTDLAV ANSIRRVFIA EVPIIAIDWV QIDANSSVLH DEFIAHRLGL IPLTSDDIVD KLQYSRDCT CEEFCPECSV EFTLDVRCNE DQTRHVTSRD LISNSPRVIP VTSRNRDNDP SDYVEQDDIL IVKLRKGQEL R LRAYAKKG FGKEHAKWNP TAGVAFEYDP DNALRHTVYP KPEEWPKSEY SELDEDESQA PYDPNGKPER FYYNVESCGS LR PETIVLS ALSGLKKKLS DLQTQLSHEI QSDVLTIN

UniProtKB: DNA-directed RNA polymerase II subunit RPB3

分子 #18: DNA-directed RNA polymerase II subunit E

• 分子: 名称: DNA-directed RNA polymerase II subunit E / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 24.644318 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MDDEEETYRL WKIRKTIMQL CHDRGYLVTQ DELDQTLEEF KAQFGDKPSE GRPRRTDLTV LVAHNDDPTD QMFVFFPEEP KVGIKTIKV YCQRMQEENI TRALIVVQQG MTPSAKQSLV DMAPKYILEQ FLQQELLINI TEHELVPEHV VMTKEEVTEL L ARYKLREN QLPRIQAGDP VARYFGIKRG QVVKIIRPSE TAGRYITYRL VQ

UniProtKB: DNA-directed RNA polymerase II subunit E

分子 #19: DNA-directed RNA polymerase II subunit F

• 分子: 名称: DNA-directed RNA polymerase II subunit F / タイプ: protein_or_peptide / ID: 19 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 14.477001 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MSDNEDNFDG DDFDDVEEDE GLDDLENAEE EGQENVEILP SGERPQANQK RITTPYMTKY ERARVLGTRA LQIAMCAPVM VELEGETDP LLIAMKELKA RKIPIIIRRY LPDGSYEDWG VDELIISD

UniProtKB: DNA-directed RNA polymerases I, II, and III subunit RPABC2

分子 #20: DNA-directed RNA polymerases I, II, and III subunit RPABC3

• 分子: 名称: DNA-directed RNA polymerases I, II, and III subunit RPABC3; タイプ: protein_or_peptide / ID: 20 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 17.162273 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MAGILFEDIF DVKDIDPEGK KFDRVSRLHC ESESFKMDLI LDVNIQIYPV DLGDKFRLVI ASTLYEDGTL DDGEYNPTDD RPSRADQFE YVMYGKVYRI EGDETSTEAA TRLSAYVSYG GLLMRLQGDA NNLHGFEVDS RVYLLMKKLA F

UniProtKB: DNA-directed RNA polymerases I, II, and III subunit RPABC3

分子 #21: DNA-directed RNA polymerase II subunit RPB9

• 分子: 名称: DNA-directed RNA polymerase II subunit RPB9 / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 14.541221 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MEPDGTYEPG FVGIRFCQEC NNMLYPKEDK ENRILLYACR NCDYQQEADN SCIYVNKITH EVDELTQIIA DVSQDPTLPR TEDHPCQKC GHKEAVFFQS HSARAEDAMR LYYVCTAPHC GHRWTE

UniProtKB: DNA-directed RNA polymerase II subunit RPB9

分子 #22: DNA-directed RNA polymerases I, II, and III subunit RPABC5

• 分子: 名称: DNA-directed RNA polymerases I, II, and III subunit RPABC5; タイプ: protein_or_peptide / ID: 22 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 7.655123 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MIIPVRCFTC GKIVGNKWEA YLGLLQAEYT EGDALDALGL KRYCCRRMLL AHVDLIEKLL NYAPLEK

UniProtKB: DNA-directed RNA polymerases I, II, and III subunit RPABC5

分子 #23: RNA_pol_L_2 domain-containing protein

• 分子: 名称: RNA_pol_L_2 domain-containing protein / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 13.310284 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MNAPPAFESF LLFEGEKKIT INKDTKVPNA CLFTINKEDH TLGNIIKSQL LKDPQVLFAG YKVPHPLEHK IIIRVQTTPD YSPQEAFTN AITDLISELS LLEERFRVAI KDKQEGIE

UniProtKB: DNA-directed RNA polymerase II subunit RPB11-a

分子 #24: RPB12

• 分子: 名称: RPB12 / タイプ: protein_or_peptide / ID: 24 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 7.018244 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MDTQKDVQPP KQQPMIYICG ECHTENEIKS RDPIRCRECG YRIMYKKRTK RLVVFDAR

UniProtKB: RNA polymerase II, I and III subunit K

分子 #25: TATA-box-binding protein

• 分子: 名称: TATA-box-binding protein / タイプ: protein_or_peptide / ID: 25 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 37.729938 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MDQNNSLPPY AQGLASPQGA MTPGIPIFSP MMPYGTGLTP QPIQNTNSLS ILEEQQRQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQ QQQQQQAVAA AAVQQSTSQQ ATQGTSGQAP QLFHSQTLTT APLPGTTPLY PSPMTPMTPI TPATPASESS G IVPQLQNI VSTVNLGCKL DLKTIALRAR NAEYNPKRFA AVIMRIREPR TTALIFSSGK MVCTGAKSEE QSRLAARKYA RV VQKLGFP AKFLDFKIQN MVGSCDVKFP IRLEGLVLTH QQFSSYEPEL FPGLIYRMIK PRIVLLIFVS GKVVLTGAKV RAE IYEAFE NIYPILKGFR KTT

UniProtKB: TATA-box-binding protein

分子 #26: Transcription initiation factor IIA subunit 1

• 分子: 名称: Transcription initiation factor IIA subunit 1 / タイプ: protein_or_peptide / ID: 26 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 41.544551 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MANSANTNTV PKLYRSVIED VINDVRDIFL DDGVDEQVLM ELKTLWENKL MQSRAVDGFH SEEQQLLLQV QQQHQPQQQQ HHHHHHHQQ AQPQQTVPQQ AQTQQVLIPA SQQATAPQVI VPDSKLIQHM NASNMSAAAT AATLALPAGV TPVQQILTNS G QLLQVVRA ANGAQYIFQP QQSVVLQQQV IPQMQPGGVQ APVIQQVLAP LPGGISPQTG VIIQPQQILF TGNKTQVIPT TV AAPTPAQ AQITATGQQQ PQAQPAQTQA PLVLQVDGTG DTSSEEDEDE EEDYDDDEEE DKEKDGAEDG QVEEEPLNSE DDV SDEEGQ ELFDTENVVV CQYDKIHRSK NKWKFHLKDG IMNLNGRDYI FSKAIGDAEW

UniProtKB: Transcription initiation factor IIA subunit 1

分子 #27: Transcription initiation factor IIA subunit 2

• 分子: 名称: Transcription initiation factor IIA subunit 2 / タイプ: protein_or_peptide / ID: 27 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 12.469091 KDa
• 組換発現: 生物種: Escherichia coli (大腸菌)

配列

文字列:

MAYQLYRNTT LGNSLQESLD ELIQSQQITP QLALQVLLQF DKAINAALAQ RVRNRVNFRG SLNTYRFCDN VWTFVLNDVE FREVTELIK VDKVKIVACD GKNTGSNTTE

UniProtKB: Transcription initiation factor IIA subunit 2

分子 #28: Transcription initiation factor TFIID subunit 3

• 分子: 名称: Transcription initiation factor TFIID subunit 3 / タイプ: protein_or_peptide / ID: 28 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 103.76932 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MCESYSRSLL RVSVAQICQA LGWDSVQLSA CHLLTDVLQR YLQQLGRGCH RYSELYGRTD PILDDVGEAF QLMGVSLHEL EDYIHNIEP VTFPHQIPSF PVSKNNVLQF PQPGSKDAEE RKEYIPDYLP PIVSSQEEEE EEQVPTDGGT SAEAMQVPLE E DDELEEEE IINDENFLGK RPLDSPEAEE LPAMKRPRLL STKGDTLDVV LLEAREPLSS INTQKIPPML SPVHVQDSTD LA PPSPEPP MLAPVAKSQM PTAKPLETKS FTPKTKTKTS SPGQKTKSPK TAQSPAMVGS PIRSPKTVSK EKKSPGRSKS PKS PKSPKV TTHIPQTPVR PETPNRTPSA TLSEKISKET IQVKQIQTPP DAGKLNSENQ PKKAVVADKT IEASIDAVIA RACA EREPD PFEFSSGSES EGDIFTSPKR ISGPECTTPK ASTSANNFTK SGSTPLPLSG GTSSSDNSWT MDASIDEVVR KAKLG TPSN MPPNFPYISS PSVSPPTPEP LHKVYEEKTK LPSSVEVKKK LKKELKTKMK KKEKQRDRER EKDKNKDKSK EKDKVK EKE KDKETGRETK YPWKEFLKEE EADPYKFKIK EFEDVDPKVK LKDGLVRKEK EKHKDKKKDR EKGKKDKDKR EKEKVKD KG REDKMKAPAP PLVLPPKELA LPLFSPATAS RVPAMLPSLL PVLPEKLFEE KEKVKEKEKK KDKKEKKKKK EKEKEKKE K EREKEKRERE KREKEKEKHK HEKIKVEPVA LAPSPVIPRL TLRVGAGQDK IVISKVVPAP EAKPAPSQNR PKTPPPAPA PAPGPMLVSP APVPLPLLAQ AAAGPALLPS PGPAASGASA KAPVRSVVTE TVSTYVIRDE WGNQIWICPG CNKPDDGSPM IGCDDCDDW YHWPCVGIMT APPEEMQWFC PKCANKKKDK KHKKRKHRAH

UniProtKB: Transcription initiation factor TFIID subunit 3

分子 #29: Transcription initiation factor TFIID subunit 4

• 分子: 名称: Transcription initiation factor TFIID subunit 4 / タイプ: protein_or_peptide / ID: 29 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 110.221883 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAAGSDLLDE VFFNSEVDEK VVSDLVGSLE SQLAASAAHH HHLAPRTPEV RAAAAGALGN HVVSGSPAGA AGAGPAAPAE GAPGAAPEP PPAGRARPGG GGPQRPGPPS PRRPLVPAGP APPAAKLRPP PEGSAGSCAP VPAAAAVAAG PEPAPAGPAK P AGPAALAA RAGPGPGPGP GPGPGPGPGK PAGPGAAQTL NGSAALLNSH HAAAPAVSLV NNGPAALLPL PKPAAPGTVI QT PPFVGAA APPAPAAPSP PAAPAPAAPA AAPPPPPPAP ATLARPPGHP AGPPTAAPAV PPPAAAQNGG SAGAAPAPAP AAG GPAGVS GQPGPGAAAA APAPGVKAES PKRVVQAAPP AAQTLAASGP ASTAASMVIG PTMQGALPSP AAVPPPAPGT PTGL PKGAA GAVTQSLSRT PTATTSGIRA TLTPTVLAPR LPQPPQNPTN IQNFQLPPGM VLVRSENGQL LMIPQQALAQ MQAQA HAQP QTTMAPRPAT PTSAPPVQIS TVQAPGTPII ARQVTPTTII KQVSQAQTTV QPSATLQRSP GVQPQLVLGG AAQTAS LGT ATAVQTGTPQ RTVPGATTTS SAATETMENV KKCKNFLSTL IKLASSGKQS TETAANVKEL VQNLLDGKIE AEDFTSR LY RELNSSPQPY LVPFLKRSLP ALRQLTPDSA AFIQQSQQQP PPPTSQATTA LTAVVLSSSV QRTAGKTAAT VTSALQPP V LSLTQPTQVG VGKQGQPTPL VIQQPPKPGA LIRPPQVTLT QTPMVALRQP HNRIMLTTPQ QIQLNPLQPV PVVKPAVLP GTKALSAVSA QAAAAQKNKL KEPGGGSFRD DDDINDVASM AGVNLSEESA RILATNSELV GTLTRSCKDE TFLLQAPLQR RILEIGKKH GITELHPDVV SYVSHATQQR LQNLVEKISE TAQQKNFSYK DDDRYEQASD VRAQLKFFEQ LDQIEKQRKD E QEREILMR AAKSRSRQED PEQLRLKQKA KEMQQQELAQ MRQRDANLTA LAAIGPRKKR KVDCPGPGSG AEGSGPGSVV PG SSGVGTP RQFTRQRITR VNLRDLIFCL ENERETSHSL LLYKAFLK

UniProtKB: Transcription initiation factor TFIID subunit 4

分子 #30: Transcription initiation factor TFIID subunit 5

• 分子: 名称: Transcription initiation factor TFIID subunit 5 / タイプ: protein_or_peptide / ID: 30 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 86.932109 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAALAEEQTE VAVKLEPEGP PTLLPPQAGD GAGEGSGGTT NNGPNGGGGN VAASSSTGGD GGTPKPTVAV SAAAPAGAAP VPAAAPDAG APHDRQTLLA VLQFLRQSKL REAEEALRRE AGLLEEAVAG SGAPGEVDSA GAEVTSALLS RVTASAPGPA A PDPPGTGA SGATVVSGSA SGPAAPGKVG SVAVEDQPDV SAVLSAYNQQ GDPTMYEEYY SGLKHFIECS LDCHRAELSQ LF YPLFVHM YLELVYNQHE NEAKSFFEKF HGDQECYYQD DLRVLSSLTK KEHMKGNETM LDFRTSKFVL RISRDSYQLL KRH LQEKQN NQIWNIVQEH LYIDIFDGMP RSKQQIDAMV GSLAGEAKRE ANKSKVFFGL LKEPEIEVPL DDEDEEGENE EGKP KKKKP KKDSIGSKSK KQDPNAPPQN RIPLPELKDS DKLDKIMNMK ETTKRVRLGP DCLPSICFYT FLNAYQGLTA VDVTD DSSL IAGGFADSTV RVWSVTPKKL RSVKQASDLS LIDKESDDVL ERIMDEKTAS ELKILYGHSG PVYGASFSPD RNYLLS SSE DGTVRLWSLQ TFTCLVGYKG HNYPVWDTQF SPYGYYFVSG GHDRVARLWA TDHYQPLRIF AGHLADVNCT RFHPNSN YV ATGSADRTVR LWDVLNGNCV RIFTGHKGPI HSLTFSPNGR FLATGATDGR VLLWDIGHGL MVGELKGHTD TVCSLRFS R DGEILASGSM DNTVRLWDAI KAFEDLETDD FTTATGHINL PENSQELLLG TYMTKSTPVV HLHFTRRNLV LAAGAYSPQ

UniProtKB: Transcription initiation factor TFIID subunit 5

分子 #31: Transcription initiation factor TFIID subunit 6

• 分子: 名称: Transcription initiation factor TFIID subunit 6 / タイプ: protein_or_peptide / ID: 31 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 72.749297 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAEEKKLKLS NTVLPSESMK VVAESMGIAQ IQEETCQLLT DEVSYRIKEI AQDALKFMHM GKRQKLTTSD IDYALKLKNV EPLYGFHAQ EFIPFRFASG GGRELYFYEE KEVDLSDIIN TPLPRVPLDV CLKAHWLSIE GCQPAIPENP PPAPKEQQKA E ATEPLKSA KPGQEEDGPL KGKGQGATTA DGKGKEKKAP PLLEGAPLRL KPRSIHELSV EQQLYYKEIT EACVGSCEAK RA EALQSIA TDPGLYQMLP RFSTFISEGV RVNVVQNNLA LLIYLMRMVK ALMDNPTLYL EKYVHELIPA VMTCIVSRQL CLR PDVDNH WALRDFAARL VAQICKHFST TTNNIQSRIT KTFTKSWVDE KTPWTTRYGS IAGLAELGHD VIKTLILPRL QQEG ERIRS VLDGPVLSNI DRIGADHVQS LLLKHCAPVL AKLRPPPDNQ DAYRAEFGSL GPLLCSQVVK ARAQAALQAQ QVNRT TLTI TQPRPTLTLS QAPQPGPRTP GLLKVPGSIA LPVQTLVSAR AAAPPQPSPP PTKFIVMSSS SSAPSTQQVL SLSTSA PGS GSTTTSPVTT TVPSVQPIVK LVSTATTAPP STAPSGPGSV QKYIVVSLPP TGEGKGGPTS HPSPVPPPAS SPSPLSG SA LCGGKQEAGD SPPPAPGTPK ANGSQPNSGS PQPAP

UniProtKB: Transcription initiation factor TFIID subunit 6

分子 #32: Transcription initiation factor TFIID subunit 9

• 分子: 名称: Transcription initiation factor TFIID subunit 9 / タイプ: protein_or_peptide / ID: 32 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 29.006838 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MESGKTASPK SMPKDAQMMA QILKDMGITE YEPRVINQML EFAFRYVTTI LDDAKIYSSH AKKATVDADD VRLAIQCRAD QSFTSPPPR DFLLDIARQR NQTPLPLIKP YSGPRLPPDR YCLTAPNYRL KSLQKKASTS AGRITVPRLS VGSVTSRPST P TLGTPTPQ TMSVSTKVGT PMSLTGQRFT VQMPTSQSPA VKASIPATSA VQNVLINPSL IGSKNILITT NMMSSQNTAN ES SNALKRK REDDDDDDDD DDDYDNL

UniProtKB: Transcription initiation factor TFIID subunit 9

分子 #33: Transcription initiation factor TFIID subunit 10

• 分子: 名称: Transcription initiation factor TFIID subunit 10 / タイプ: protein_or_peptide / ID: 33 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 21.731248 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MSCSGSGADP EAAPASAASA PGPAPPVSAP AALPSSTAAE NKASPAGTAG GPGAGAAAGG TGPLAARAGE PAERRGAAPV SAGGAAPPE GAISNGVYVL PSAANGDVKP VVSSTPLVDF LMQLEDYTPT IPDAVTGYYL NRAGFEASDP RIIRLISLAA Q KFISDIAN DALQHCKMKG TASGSSRSKS KDRKYTLTME DLTPALSEYG INVKKPHYFT

UniProtKB: Transcription initiation factor TFIID subunit 10

分子 #34: Transcription initiation factor TFIID subunit 11

• 分子: 名称: Transcription initiation factor TFIID subunit 11 / タイプ: protein_or_peptide / ID: 34 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 23.340094 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MDDAHESPSD KGGETGESDE TAAVPGDPGA TDTDGIPEET DGDADVDLKE AAAEEGELES QDVSDLTTVE REDSSLLNPA AKKLKIDTK EKKEKKQKVD EDEIQKMQIL VSSFSEEQLN RYEMYRRSAF PKAAIKRLIQ SITGTSVSQN VVIAMSGISK V FVGEVVEE ALDVCEKWGE MPPLQPKHMR EAVRRLKSKG QIPNSKHKKI IFF

UniProtKB: Transcription initiation factor TFIID subunit 11

分子 #35: Transcription initiation factor TFIID subunit 12

• 分子: 名称: Transcription initiation factor TFIID subunit 12 / タイプ: protein_or_peptide / ID: 35 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 17.948467 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MNQFGPSALI NLSNFSSIKP EPASTPPQGS MANSTAVVKI PGTPGAGGRL SPENNQVLTK KKLQDLVREV DPNEQLDEDV EEMLLQIAD DFIESVVTAA CQLARHRKSS TLEVKDVQLH LERQWNMWIP GFGSEEIRPY KKACTTEAHK QRMALIRKTT K K

UniProtKB: Transcription initiation factor TFIID subunit 12

分子 #36: Transcription initiation factor TFIID subunit 13

• 分子: 名称: Transcription initiation factor TFIID subunit 13 / タイプ: protein_or_peptide / ID: 36 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 14.307068 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MADEEEDPTF EEENEEIGGG AEGGQGKRKR LFSKELRCMM YGFGDDQNPY TESVDILEDL VIEFITEMTH KAMSIGRQGR VQVEDIVFL IRKDPRKFAR VKDLLTMNEE LKRARKAFDE ANYGS

UniProtKB: Transcription initiation factor TFIID subunit 13

分子 #37: Transcription initiation factor TFIID subunit 7

• 分子: 名称: Transcription initiation factor TFIID subunit 7 / タイプ: protein_or_peptide / ID: 37 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 40.325117 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MSKSKDDAPH ELESQFILRL PPEYASTVRR AVQSGHVNLK DRLTIELHPD GRHGIVRVDR VPLASKLVDL PCVMESLKTI DKKTFYKTA DICQMLVSTV DGDLYPPVEE PVASTDPKAS KKKDKDKEKK FIWNHGITLP LKNVRKRRFR KTAKKKYIES P DVEKEVKR LLSTDAEAVS TRWEIIAEDE TKEAENQGLD ISSPGMSGHR QGHDSLEHDE LREIFNDLSS SSEDEDETQH QD EEDINII DTEEDLERQL QDKLNESDEQ HQENEGTNQL VMGIQKQIDN MKGKLQETQD RAKRQEDLIM KVENLALKNR FQA VLDELK QKEDREKEQL SSLQEELESL LEK

UniProtKB: Transcription initiation factor TFIID subunit 7

分子 #38: Transcription initiation factor TFIID subunit 8

• 分子: 名称: Transcription initiation factor TFIID subunit 8 / タイプ: protein_or_peptide / ID: 38 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 34.304359 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MADAAATAGA GGSGTRSGSK QSTNPADNYH LARRRTLQVV VSSLLTEAGF ESAEKASVET LTEMLQSYIS EIGRSAKSYC EHTARTQPT LSDIVVTLVE MGFNVDTLPA YAKRSQRMVI TAPPVTNQPV TPKALTAGQN RPHPPHIPSH FPEFPDPHTY I KTPTYREP VSDYQVLREK AASQRRDVER ALTRFMAKTG ETQSLFKDDV STFPLIAARP FTIPYLTALL PSELEMQQME ET DSSEQDE QTDTENLALH ISMEDSGAEK ENTSVLQQNP SLSGSRNGEE NIIDNPYLRP VKKPKIRRKK SLS

UniProtKB: Transcription initiation factor TFIID subunit 8

分子 #39: CDK-activating kinase assembly factor MAT1

• 分子: 名称: CDK-activating kinase assembly factor MAT1 / タイプ: protein_or_peptide / ID: 39 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 35.873965 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MDDQGCPRCK TTKYRNPSLK LMVNVCGHTL CESCVDLLFV RGAGNCPECG TPLRKSNFRV QLFEDPTVDK EVEIRKKVLK IYNKREEDF PSLREYNDFL EEVEEIVFNL TNNVDLDNTK KKMEIYQKEN KDVIQKNKLK LTREQEELEE ALEVERQENE Q RRLFIQKE EQLQQILKRK NKQAFLDELE SSDLPVALLL AQHKDRSTQL EMQLEKPKPV KPVTFSTGIK MGQHISLAPI HK LEEALYE YQPLQIETYG PHVPELEMLG RLGYLNHVRA ASPQDLAGGY TSSLACHRAL QDAFSGLFWQ PS

UniProtKB: CDK-activating kinase assembly factor MAT1

分子 #40: General transcription factor IIH subunit 3

• 分子: 名称: General transcription factor IIH subunit 3 / タイプ: protein_or_peptide / ID: 40 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 34.416008 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MVSDEDELNL LVIVVDANPI WWGKQALKES QFTLSKCIDA VMVLGNSHLF MNRSNKLAVI ASHIQESRFL YPGKNGRLGD FFGDPGNPP EFNPSGSKDG KYELLTSANE VIVEEIKDLM TKSDIKGQHT ETLLAGSLAK ALCYIHRMNK EVKDNQEMKS R ILVIKAAE DSALQYMNFM NVIFAAQKQN ILIDACVLDS DSGLLQQACD ITGGLYLKVP QMPSLLQYLL WVFLPDQDQR SQ LILPPPV HVDYRAACFC HRNLIEIGYV CSVCLSIFCN FSPICTTCET AFKISLPPVL KAKKKKLKVS A

UniProtKB: General transcription factor IIH subunit 3

分子 #41: General transcription factor IIH subunit 2

• 分子: 名称: General transcription factor IIH subunit 2 / タイプ: protein_or_peptide / ID: 41 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 44.481996 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MDEEPERTKR WEGGYERTWE ILKEDESGSL KATIEDILFK AKRKRVFEHH GQVRLGMMRH LYVVVDGSRT MEDQDLKPNR LTCTLKLLE YFVEEYFDQN PISQIGIIVT KSKRAEKLTE LSGNPRKHIT SLKKAVDMTC HGEPSLYNSL SIAMQTLKHM P GHTSREVL IIFSSLTTCD PSNIYDLIKT LKAAKIRVSV IGLSAEVRVC TVLARETGGT YHVILDESHY KELLTHHVSP PP ASSSSEC SLIRMGFPQH TIASLSDQDA KPSFSMAHLD GNTEPGLTLG GYFCPQCRAK YCELPVECKI CGLTLVSAPH LAR SYHHLF PLDAFQEIPL EEYNGERFCY GCQGELKDQH VYVCAVCQNV FCVDCDVFVH DSLHCCPGCI HKIPAPSGV

UniProtKB: General transcription factor IIH subunit 2

分子 #42: General transcription and DNA repair factor IIH helicase subunit XPB

• 分子: 名称: General transcription and DNA repair factor IIH helicase subunit XPB; タイプ: protein_or_peptide / ID: 42 / コピー数: 1 / 光学異性体: LEVO / EC番号: DNA helicase
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 89.404734 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MGKRDRADRD KKKSRKRHYE DEEDDEEDAP GNDPQEAVPS AAGKQVDESG TKVDEYGAKD YRLQMPLKDD HTSRPLWVAP DGHIFLEAF SPVYKYAQDF LVAIAEPVCR PTHVHEYKLT AYSLYAAVSV GLQTSDITEY LRKLSKTGVP DGIMQFIKLC T VSYGKVKL VLKHNRYFVE SCHPDVIQHL LQDPVIRECR LRNSEGEATE LITETFTSKS AISKTAESSG GPSTSRVTDP QG KSDIPMD LFDFYEQMDK DEEEEEETQT VSFEVKQEMI EELQKRCIHL EYPLLAEYDF RNDSVNPDIN IDLKPTAVLR PYQ EKSLRK MFGNGRARSG VIVLPCGAGK SLVGVTAACT VRKRCLVLGN SAVSVEQWKA QFKMWSTIDD SQICRFTSDA KDKP IGCSV AISTYSMLGH TTKRSWEAER VMEWLKTQEW GLMILDEVHT IPAKMFRRVL TIVQAHCKLG LTATLVREDD KIVDL NFLI GPKLYEANWM ELQNNGYIAK VQCAEVWCPM SPEFYREYVA IKTKKRILLY TMNPNKFRAC QFLIKFHERR NDKIIV FAD NVFALKEYAI RLNKPYIYGP TSQGERMQIL QNFKHNPKIN TIFISKVGDT SFDLPEANVL IQISSHGGSR RQEAQRL GR VLRAKKGMVA EEYNAFFYSL VSQDTQEMAY STKRQRFLVD QGYSFKVITK LAGMEEEDLA FSTKEEQQQL LQKVLAAT D LDAEEEVVAG EFGSRSSQAS RRFGTMSSMS GADDTVYMEY HSSRSKAPSK HVHPLFKRFR K

UniProtKB: General transcription and DNA repair factor IIH helicase/translocase subunit XPB

分子 #43: General transcription factor IIH subunit 5

• 分子: 名称: General transcription factor IIH subunit 5 / タイプ: protein_or_peptide / ID: 43 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 8.060362 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MVNVLKGVLI ECDPAMKQFL LYLDESNALG KKFIIQDIDD THVFVIAELV NVLQERVGEL MDQNAFSLTQ K

UniProtKB: General transcription factor IIH subunit 5

分子 #44: Cyclin-dependent kinase 7

• 分子: 名称: Cyclin-dependent kinase 7 / タイプ: protein_or_peptide / ID: 44 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 39.032242 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MALDVKSRAK RYEKLDFLGE GQFATVYKAR DKNTNQIVAI AKIKLGHRSE AKDGINRTAL REIKLLQELS HPNIIGLLDA FGHKSNISL VFDFMETDLE VIIKDNSLVL TPSHIKAYML MTLQGLEYLH QHWILHRDLK PNNLLLDENG VLKLADFGLA K SFGSPNRA YTHQVVTRWY RAPELLFGAR MYGVGVDMWA VGCILAELLL RVPFLPGDSD LDQLTRIFET LGTPTEEQWP DM CSLPDYV TFKSFPGIPL HHIFSAAGDD LLDLIQGLFL FNPCARITAT QALKMKYFSN RPGPTPGCQL PRPNCPVETL KEQ SNPALA IKRKRTEALE QGGLPKKLIF

UniProtKB: Cyclin-dependent kinase 7

分子 #45: Cyclin-H

• 分子: 名称: Cyclin-H / タイプ: protein_or_peptide / ID: 45 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 37.695473 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MYHNSSQKRH WTFSSEEQLA RLRADANRKF RCKAVANGKV LPNDPVFLEP HEEMTLCKYY EKRLLEFCSV FKPAMPRSVV GTACMYFKR FYLNNSVMEY HPRIIMLTCA FLACKVDEFN VSSPQFVGNL RESPLGQEKA LEQILEYELL LIQQLNFHLI V HNPYRPFE GFLIDLKTRY PILENPEILR KTADDFLNRI ALTDAYLLYT PSQIALTAIL SSASRAGITM ESYLSESLML KE NRTCLSQ LLDIMKSMRN LVKKYEPPRS EEVAVLKQKL ERCHSAELAL NVITKKRKGY EDDDYVSKKS KHEEEEWTDD DLV ESL

UniProtKB: Cyclin-H

分子 #46: DNA-directed RNA polymerase II subunit RPB4

• 分子: 名称: DNA-directed RNA polymerase II subunit RPB4 / タイプ: protein_or_peptide / ID: 46 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 16.331255 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MAAGGSDPRA GDVEEDASQL IFPKEFETAE TLLNSEVHML LEHRKQQNES AEDEQELSEV FMKTLNYTAR FSRFKNRETI ASVRSLLLQ KKLHKFELAC LANLCPETAE ESKALIPSLE GRFEDEELQQ ILDDIQTKRS FQY

UniProtKB: DNA-directed RNA polymerase II subunit RPB4

分子 #47: DNA-directed RNA polymerase II subunit RPB7

• 分子: 名称: DNA-directed RNA polymerase II subunit RPB7 / タイプ: protein_or_peptide / ID: 47 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Sus scrofa (ブタ)
• 分子量: 理論値: 19.314283 KDa
• 組換発現: 生物種: Sus scrofa (ブタ)

配列

文字列:

MFYHISLEHE ILLHPRYFGP NLLNTVKQKL FTEVEGTCTG KYGFVIAVTT IDNIGAGVIQ PGRGFVLYPV KYKAIVFRPF KGEVVDAVV TQVNKVGLFT EIGPMSCFIS RHSIPSEMEF DPNSNPPCYK TMDEDIVIQQ DDEIRLKIVG TRVDKNDIFA I GSLMDDYL GLVS

UniProtKB: DNA-directed RNA polymerase subunit

分子 #48: Mediator of RNA polymerase II transcription subunit 7

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 7; タイプ: protein_or_peptide / ID: 48 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 27.285281 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MGEPQQVSAL PPPPMQYIKE YTDENIQEGL APKPPPPIKD SYMMFGNQFQ CDDLIIRPLE SQGIERLHPM QFDHKKELRK LNMSILINF LDLLDILIRS PGSIKREEKL EDLKLLFVHV HHLINEYRPH QARETLRVMM EVQKRQRLET AERFQKHLER V IEMIQNCL ASLPDDLPHS EAGMRVKTEP MDADDSNNCT GQNEHQRENS GHRRDQIIEK DAALCVLIDE MNERP

UniProtKB: Mediator of RNA polymerase II transcription subunit 7

分子 #49: Mediator of RNA polymerase II transcription subunit 10

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 10; タイプ: protein_or_peptide / ID: 49 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 15.710969 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAEKFDHLEE HLEKFVENIR QLGIIVSDFQ PSSQAGLNQK LNFIVTGLQD IDKCRQQLHD ITVPLEVFEY IDQGRNPQLY TKECLERAL AKNEQVKGKI DTMKKFKSLL IQELSKVFPE DMAKYRSIRG EDHPPS

UniProtKB: Mediator of RNA polymerase II transcription subunit 10

分子 #50: Mediator of RNA polymerase II transcription subunit 14

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 14; タイプ: protein_or_peptide / ID: 50 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 160.787594 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAPVQLENHQ LVPPGGGGGG SGGPPSAPAP PPPGAAVAAA AAAAASPGYR LSTLIEFLLH RAYSELMVLT DLLPRKSDVE RKIEIVQFA SRTRQLFVRL LALVKWANNA GKVEKCAMIS SFLDQQAILF VDTADRLASL ARDALVHARL PSFAIPYAID V LTTGSYPR LPTCIRDKII PPDPITKIEK QATLHQLNQI LRHRLVTTDL PPQLANLTVA NGRVKFRVEG EFEATLTVMG DD PDVPWRL LKLEILVEDK ETGDGRALVH SMQISFIHQL VQSRLFADEK PLQDMYNCLH SFCLSLQLEV LHSQTLMLIR ERW GDLVQV ERYHAGKCLS LSVWNQQVLG RKTGTASVHK VTIKIDENDV SKPLQIFHDP PLPASDSKLV ERAMKIDHLS IEKL LIDSV HARAHQKLQE LKAILRGFNA NENSSIETAL PALVVPILEP CGNSECLHIF VDLHSGMFQL MLYGLDQATL DDMEK SVND DMKRIIPWIQ QLKFWLGQQR CKQSIKHLPT ISSETLQLSN YSTHPIGNLS KNKLFIKLTR LPQYYIVVEM LEVPNK PTQ LSYKYYFMSV NAADREDSPA MALLLQQFKE NIQDLVFRTK TGKQTRTNAK RKLSDDPCPV ESKKTKRAGE MCAFNKV LA HFVAMCDTNM PFVGLRLELS NLEIPHQGVQ VEGDGFSHAI RLLKIPPCKG ITEETQKALD RSLLDCTFRL QGRNNRTW V AELVFANCPL NGTSTREQGP SRHVYLTYEN LLSEPVGGRK VVEMFLNDWN SIARLYECVL EFARSLPDIP AHLNIFSEV RVYNYRKLIL CYGTTKGSSI SIQWNSIHQK FHISLGTVGP NSGCSNCHNT ILHQLQEMFN KTPNVVQLLQ VLFDTQAPLN AINKLPTVP MLGLTQRTNT AYQCFSILPQ SSTHIRLAFR NMYCIDIYCR SRGVVAIRDG AYSLFDNSKL VEGFYPAPGL K TFLNMFVD SNQDARRRSV NEDDNPPSPI GGDMMDSLIS QLQPPPQQQP FPKQPGTSGA YPLTSPPTSY HSTVNQSPSM MH TQSPGNL HAASSPSGAL RAPSPASFVP TPPPSSHGIS IGPGASFASP HGTLDPSSPY TMVSPSGRAG NWPGSPQVSG PSP AARMPG MSPANPSLHS PVPDASHSPR AGTSSQTMPT NMPPPRKLPQ RSWAASIPTI LTHSALNILL LPSPTPGLVP GLAG SYLCS PLERFLGSVI MRRHLQRIIQ QETLQLINSN EPGVIMFKTD ALKCRVALSP KTNQTLQLKV TPENAGQWKP DELQV LEKF FETRVAGPPF KANTLIAFTK LLGAPTHILR DCVHIMKLEL FPDQATQLKW NVQFCLTIPP SAPPIAPPGT PAVVLK SKM LFFLQLTQKT SVPPQEPVSI IVPIIYDMAS GTTQQADIPR QQNSSVAAPM MVSNILKRFA EMNPPRQGEC TIFAAVR DL MANLTLPPGG RP

UniProtKB: Mediator of RNA polymerase II transcription subunit 14

分子 #51: Mediator of RNA polymerase II transcription subunit 19

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 19; タイプ: protein_or_peptide / ID: 51 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 26.321146 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MENFTALFGA QADPPPPPTA LGFGPGKPPP PPPPPAGGGP GTAPPPTAAT APPGADKSGA GCGPFYLMRE LPGSTELTGS TNLITHYNL EQAYNKFCGK KVKEKLSNFL PDLPGMIDLP GSHDNSSLRS LIEKPPILSS SFNPITGTML AGFRLHTGPL P EQCRLMHI QPPKKKNKHK HKQSRTQDPV PPETPSDSDH KKKKKKKEED PDRKRKKKEK KKKKNRHSPD HPGMGSSQAS SS SSLR

UniProtKB: Mediator of RNA polymerase II transcription subunit 19

分子 #52: Mediator of RNA polymerase II transcription subunit 21

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 21; タイプ: protein_or_peptide / ID: 52 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 15.575234 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MADRLTQLQD AVNSLADQFC NAIGVLQQCG PPASFNNIQT AINKDQPANP TEEYAQLFAA LIARTAKDID VLIDSLPSEE STAALQAAS LYKLEEENHE AATCLEDVVY RGDMLLEKIQ SALADIAQSQ LKTRSGTHSQ SLPDS

UniProtKB: Mediator of RNA polymerase II transcription subunit 21

分子 #53: Mediator of RNA polymerase II transcription subunit 1

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 1; タイプ: protein_or_peptide / ID: 53 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 168.697328 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MKAQGETEES EKLSKMSSLL ERLHAKFNQN RPWSETIKLV RQVMEKRVVM SSGGHQHLVS CLETLQKALK VTSLPAMTDR LESIARQNG LGSHLSASGT ECYITSDMFY VEVQLDPAGQ LCDVKVAHHG ENPVSCPELV QQLREKNFDE FSKHLKGLVN L YNLPGDNK LKTKMYLALQ SLEQDLSKMA IMYWKATNAG PLDKILHGSV GYLTPRSGGH LMNLKYYVSP SDLLDDKTAS PI ILHENNV SRSLGMNASV TIEGTSAVYK LPIAPLIMGS HPVDNKWTPS FSSITSANSV DLPACFFLKF PQPIPVSRAF VQK LQNCTG IPLFETQPTY APLYELITQF ELSKDPDPIP LNHNMRFYAA LPGQQHCYFL NKDAPLPDGR SLQGTLVSKI TFQH PGRVP LILNLIRHQV AYNTLIGSCV KRTILKEDSP GLLQFEVCPL SESRFSVSFQ HPVNDSLVCV VMDVQDSTHV SCKLY KGLS DALICTDDFI AKVVQRCMSI PVTMRAIRRK AETIQADTPA LSLIAETVED MVKKNLPPAS SPGYGMTTGN NPMSGT TTP TNTFPGGPIT TLFNMSMSIK DRHESVGHGE DFSKVSQNPI LTSLLQITGN GGSTIGSSPT PPHHTPPPVS SMAGNTK NH PMLMNLLKDN PAQDFSTLYG SSPLERQNSS SGSPRMEICS GSNKTKKKKS SRLPPEKPKH QTEDDFQREL FSMDVDSQ N PIFDVNMTAD TLDTPHITPA PSQCSTPPTT YPQPVPHPQP SIQRMVRLSS SDSIGPDVTD ILSDIAEEAS KLPSTSDDC PAIGTPLRDS SSSGHSQSTL FDSDVFQTNN NENPYTDPAD LIADAAGSPS SDSPTNHFFH DGVDFNPDLL NSQSQSGFGE EYFDESSQS GDNDDFKGFA SQALNTLGVP MLGGDNGETK FKGNNQADTV DFSIISVAGK ALAPADLMEH HSGSQGPLLT T GDLGKEKT QKRVKEGNGT SNSTLSGPGL DSKPGKRSRT PSNDGKSKDK PPKRKKADTE GKSPSHSSSN RPFTPPTSTG GS KSPGSAG RSQTPPGVAT PPIPKITIQI PKGTVMVGKP SSHSQYTSSG SVSSSGSKSH HSHSSSSSSS ASTSGKMKSS KSE GSSSSK LSSSMYSSQG SSGSSQSKNS SQSGGKPGSS PITKHGLSSG SSSTKMKPQG KPSSLMNPSL SKPNISPSHS RPPG GSDKL ASPMKPVPGT PPSSKAKSPI SSGSGGSHMS GTSSSSGMKS SSGLGSSGSL SQKTPPSSNS CTASSSSFSS SGSSM SSSQ NQHGSSKGKS PSRNKKPSLT AVIDKLKHGV VTSGPGGEDP LDGQMGVSTN SSSHPMSSKH NMSGGEFQGK REKSDK DKS KVSTSGSSVD SSKKTSESKN VGSTGVAKII ISKHDGGSPS IKAKVTLQKP GESSGEGLRP QMASSKNYGS PLISGST PK HERGSPSHSK SPAYTPQNLD SESESGSSIA EKSYQNSPSS DDGIRPLPEY STEKHKKHKK EKKKVKDKDR DRDRDKDR D KKKSHSIKPE SWSKSPISSD QSLSMTSNTI LSADRPSRLS PDFMIGEEDD DLMDVALIGN

UniProtKB: Mediator of RNA polymerase II transcription subunit 1

分子 #54: Mediator of RNA polymerase II transcription subunit 4

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 4; タイプ: protein_or_peptide / ID: 54 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 29.781424 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAASSSGEKE KERLGGGLGV AGGNSTRERL LSALEDLEVL SRELIEMLAI SRNQKLLQAG EENQVLELLI HRDGEFQELM KLALNQGKI HHEMQVLEKE VEKRDSDIQQ LQKQLKEAEQ ILATAVYQAK EKLKSIEKAR KGAISSEEII KYAHRISASN A VCAPLTWV PGDPRRPYPT DLEMRSGLLG QMNNPSTNGV NGHLPGDALA AGRLPDVLAP QYPWQSNDMS MNMLPPNHSS DF LLEPPGH NKENEDDVEI MSTDSSSSSS ESD

UniProtKB: Mediator of RNA polymerase II transcription subunit 4

分子 #55: Mediator of RNA polymerase II transcription subunit 6

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 6; タイプ: protein_or_peptide / ID: 55 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 28.464627 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAAVDIRDNL LGISWVDSSW IPILNSGSVL DYFSERSNPF YDRTCNNEVV KMQRLTLEHL NQMVGIEYIL LHAQEPILFI IRKQQRQSP AQVIPLADYY IIAGVIYQAP DLGSVINSRV LTAVHGIQSA FDEAMSYCRY HPSKGYWWHF KDHEEQDKVR P KAKRKEEP SSIFQRQRVD ALLLDLRQKF PPKFVQLKPG EKPVPVDQTK KEAEPIPETV KPEEKETTKN VQQTVSAKGP PE KRMRLQ

UniProtKB: Mediator of RNA polymerase II transcription subunit 6

分子 #56: Mediator of RNA polymerase II transcription subunit 9

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 9; タイプ: protein_or_peptide / ID: 56 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 16.42275 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MASAGVAAGR QAEDVLPPTS DQPLPDTKPL PPPQPPPVPA PQPQQSPAPR PQSPARAREE ENYSFLPLVH NIIKCMDKDS PEVHQDLNA LKSKFQEMRK LISTMPGIHL SPEQQQQQLQ SLREQVRTKN ELLQKYKSLC MFEIPKE

UniProtKB: Mediator of RNA polymerase II transcription subunit 9

分子 #57: Mediator of RNA polymerase II transcription subunit 31

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 31; タイプ: protein_or_peptide / ID: 57 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 15.826116 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAAAVAMETD DAGNRLRFQL ELEFVQCLAN PNYLNFLAQR GYFKDKAFVN YLKYLLYWKD PEYAKYLKYP QCLHMLELLQ YEHFRKELV NAQCAKFIDE QQILHWQHYS RKRMRLQQAL AEQQQQNNTS GK

UniProtKB: Mediator of RNA polymerase II transcription subunit 31

分子 #58: Mediator of RNA polymerase II transcription subunit 17

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 17; タイプ: protein_or_peptide / ID: 58 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 72.984047 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MSGVRAVRIS IESACEKQVH EVGLDGTETY LPPLSMSQNL ARLAQRIDFS QGSGSEEEEA AGTEGDAQEW PGAGSSADQD DEEGVVKFQ PSLWPWDSVR NNLRSALTEM CVLYDVLSIV RDKKFMTLDP VSQDALPPKQ NPQTLQLISK KKSLAGAAQI L LKGAERLT KSVTENQENK LQRDFNSELL RLRQHWKLRK VGDKILGDLS YRSAGSLFPH HGTFEVIKNT DLDLDKKIPE DY CPLDVQI PSDLEGSAYI KVSIQKQAPD IGDLGTVNLF KRPLPKSKPG SPHWQTKLEA AQNVLLCKEI FAQLSREAVQ IKS QVPHIV VKNQIISQPF PSLQLSISLC HSSNDKKSQK FATEKQCPED HLYVLEHNLH LLIREFHKQT LSSIMMPHPA SAPF GHKRM RLSGPQAFDK NEINSLQSSE GLLEKIIKQA KHIFLRSRAA ATIDSLASRI EDPQIQAHWS NINDVYESSV KVLIT SQGY EQICKSIQLQ LNIGVEQIRV VHRDGRVITL SYQEQELQDF LLSQMSQHQV HAVQQLAKVM GWQVLSFSNH VGLGPI ESI GNASAITVAS PSGDYAISVR NGPESGSKIM VQFPRNQCKD LPKSDVLQDN KWSHLRGPFK EVQWNKMEGR NFVYKME LL MSALSPCLL

UniProtKB: Mediator of RNA polymerase II transcription subunit 17

分子 #59: Mediator of RNA polymerase II transcription subunit 26

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 26; タイプ: protein_or_peptide / ID: 59 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 65.544438 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MTAAPASPQQ IRDRLLQAID PQSNIRNMVA VLEVISSLEK YPITKEALEE TRLGKLINDV RKKTKNEELA KRAKKLLRSW QKLIEPAHQ HEAALRGLAG ATGSANGGAH NCRPEVGAAG PPRSIHDLKS RNDLQRLPGQ RLDRLGSRKR RGDQRDLGHP G PPPKVSKA SHDPLVPNSS PLPTNGISGS PESFASSLDG SGHAGPEGSR LERDENDKHS GKIPVNAVRP HTSSPGLGKP PG PCLQPKA SVLQQLDRVD ETPGPPHPKG PPRCSFSPRN SRHEGSFARQ QSLYAPKGSV PSPSPRPQAL DATQVPSPLP LAQ PSTPPV RRLELLPSAE SPVCWLEQPE SHQRLAGPGC KAGLSPAEPL LSRAGFSPDS SKADSDAASS GGSDSKKKKR YRPR DYTVN LDGQVAEAGV KPVRLKERKL TFDPMTRQIK PLTQKEPVRA DSPVHMEQQS RTELDKQEAK ASLQSPFEQT NWKEL SRNE IIQSYLSRQS SLLSSSGAQT PGAHHFMSEY LKQEESTRQG ARQLHVLVPQ SPPTDLPGLT REVTQDDLDR IQASQW PGV NGCQDTQGNW YDWTQCISLD PHGDDGRLNI LPYVCLD

UniProtKB: Mediator of RNA polymerase II transcription subunit 26

分子 #60: Mediator of RNA polymerase II transcription subunit 29

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 29; タイプ: protein_or_peptide / ID: 60 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 21.089801 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAASQQQASA ASSAAGVSGP SSAGGPGPQQ QPQPPAQLVG PAQSGLLQQQ QQDFDPVQRY KMLIPQLKES LQTLMKVAAQ NLIQNTNID NGQKSSDGPI QRFDKCLEEF YALCDQLELC LRLAHECLSQ SCDSAKHSPT LVPTATKPDA VQPDSLPYPQ Y LAVIKAQI SCAKDIHTAL LDCANKVTGK TPAPPAGPGG TL

UniProtKB: Mediator of RNA polymerase II transcription subunit 29

分子 #61: Mediator of RNA polymerase II transcription subunit 27

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 27; タイプ: protein_or_peptide / ID: 61 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 35.478742 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MADVINVSVN LEAFSQAISA IQALRSSVSR VFDCLKDGMR NKETLEGREK AFIAHFQDNL HSVNRDLNEL ERLSNLVGKP SENHPLHNS GLLSLDPVQD KTPLYSQLLQ AYKWSNKLQY HAGLASGLLN QQSLKRSANQ MGVSAKRRPK AQPTTLVLPP Q YVDDVISR IDRMFPEMSI HLSRPNGTSA MLLVTLGKVL KVIVVMRSLF IDRTIVKGYN ENVYTEDGKL DIWSKSNYQV FQ KVTDHAT TALLHYQLPQ MPDVVVRSFM TWLRSYIKLF QAPCQRCGKF LQDGLPPTWR DFRTLEAFHD TCRQ

UniProtKB: Mediator of RNA polymerase II transcription subunit 27

分子 #62: Mediator of RNA polymerase II transcription subunit 28

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 28; タイプ: protein_or_peptide / ID: 62 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 19.540107 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAAPLGGMFS GQPPGPPQAP PGLPGQASLL QAAPGAPRPS SSTLVDELES SFEACFASLV SQDYVNGTDQ EEIRTGVDQC IQKFLDIAR QTECFFLQKR LQLSVQKPEQ VIKEDVSELR NELQRKDALV QKHLTKLRHW QQVLEDINVQ HKKPADIPQG S LAYLEQAS ANIPAPLKPT

UniProtKB: Mediator of RNA polymerase II transcription subunit 28

分子 #63: Mediator of RNA polymerase II transcription subunit 30

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 30; タイプ: protein_or_peptide / ID: 63 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 20.301229 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MSTPPLAASG MAPGPFAGPQ AQQAAREVNT ASLCRIGQET VQDIVYRTME IFQLLRNMQL PNGVTYHTGT YQDRLTKLQD NLRQLSVLF RKLRLVYDKC NENCGGMDPI PVEQLIPYVE EDGSKNDDRA GPPRFASEER REIAEVNKKL KQKNQQLKQI M DQLRNLIW DINAMLAMRN

UniProtKB: Mediator of RNA polymerase II transcription subunit 30

分子 #64: Mediator of RNA polymerase II transcription subunit 15

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 15; タイプ: protein_or_peptide / ID: 64 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 86.830102 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MDVSGQETDW RSTAFRQKLV SQIEDAMRKA GVAHSKSSKD MESHVFLKAK TRDEYLSLVA RLIIHFRDIH NKKSQASVSD PMNALQSLT GGPAAGAAGI GMPPRGPGQS LGGMGSLGAM GQPMSLSGQP PPGTSGMAPH SMAVVSTATP QTQLQLQQVA L QQQQQQQQ FQQQQQAALQ QQQQQQQQQQ FQAQQSAMQQ QFQAVVQQQQ QLQQQQQQQQ HLIKLHHQNQ QQIQQQQQQL QR IAQLQLQ QQQQQQQQQQ QQQQQALQAQ PPIQQPPMQQ PQPPPSQALP QQLQQMHHTQ HHQPPPQPQQ PPVAQNQPSQ LPP QSQTQP LVSQAQALPG QMLYTQPPLK FVRAPMVVQQ PPVQPQVQQQ QTAVQTAQAA QMVAPGVQMI TEALAQGGMH IRAR FPPTT AVSAIPSSSI PLGRQPMAQV SQSSLPMLSS PSPGQQVQTP QSMPPPPQPS PQPGQPSSQP NSNVSSGPAP SPSSF LPSP SPQPSQSPVT ARTPQNFSVP SPGPLNTPVN PSSVMSPAGS SQAEEQQYLD KLKQLSKYIE PLRRMINKID KNEDRK KDL SKMKSLLDIL TDPSKRCPLK TLQKCEIALE KLKNDMAVPT PPPPPVPPTK QQYLCQPLLD AVLANIRSPV FNHSLYR TF VPAMTAIHGP PITAPVVCTR KRRLEDDERQ SIPSVLQGEV ARLDPKFLVN LDPSHCSNNG TVHLICKLDD KDLPSVPP L ELSVPADYPA QSPLWIDRQW QYDANPFLQS VHRCMTSRLL QLPDKHSVTA LLNTWAQSVH QACLSAA

UniProtKB: Mediator of RNA polymerase II transcription subunit 15

分子 #65: Isoform 2 of Mediator of RNA polymerase II transcription subunit 8

• 分子: 名称: Isoform 2 of Mediator of RNA polymerase II transcription subunit 8; タイプ: protein_or_peptide / ID: 65 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 29.112906 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MQREEKQLEA SLDALLSQVA DLKNSLGSFI CKLENEYGRL TWPSVLDSFA LLSGQLNTLN KVLKHEKTPL FRNQVIIPLV LSPDRDEDL MRQTEGRVPV FSHEVVPDHL RTKPDPEVEE QEKQLTTDAA RIGADAAQKQ IQSLNKMCSN LLEKISKEER E SESGGLRP NKQTFNPTDT NALVAAVAFG KGLSNWRPSG SSGPGQAGQP GAGTILAGTS GLQQVQMAGA PSQQQPMLSG VQ MAQAGQP GKMPSGIKTN IKSASMHPYQ R

UniProtKB: Mediator of RNA polymerase II transcription subunit 8

分子 #66: Mediator of RNA polymerase II transcription subunit 11

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 11; タイプ: protein_or_peptide / ID: 66 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 13.145829 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MATYSLANER LRALEDIERE IGAILQNAGT VILELSKEKT NERLLDRQAA AFTASVQHVE AELSAQIRYL TQVATGQPHE GSSYSSRKD CQMALKRVDY ARLKLSDVAR TCEQMLEN

UniProtKB: Mediator of RNA polymerase II transcription subunit 11

分子 #67: Mediator of RNA polymerase II transcription subunit 18

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 18; タイプ: protein_or_peptide / ID: 67 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 23.69373 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MEAPPVTMMP VTGGTINMME YLLQGSVLDH SLESLIHRLR GLCDNMEPET FLDHEMVFLL KGQQASPFVL RARRSMDRAG APWHLRYLG QPEMGDKNRH ALVRNCVDIA TSENLTDFLM EMGFRMDHEF VAKGHLFRKG IMKIMVYKIF RILVPGNTDS T EALSLSYL VELSVVAPAG QDMVSDDMKN FAEQLKPLVH LEKIDPKRLM

UniProtKB: Mediator of RNA polymerase II transcription subunit 18

分子 #68: Mediator of RNA polymerase II transcription subunit 20

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 20; タイプ: protein_or_peptide / ID: 68 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 23.243762 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MGVTCVSQMP VAEGKSVQQT VELLTRKLEM LGAEKQGTFC VDCETYHTAA STLGSQGQTG KLMYVMHNSE YPLSCFALFE NGPCLIADT NFDVLMVKLK GFFQSAKASK IETRGTRYQY CDFLVKVGTV TMGPSARGIS VEVEYGPCVV ASDCWSLLLE F LQSFLGSH TPGAPAVFGN RHDAVYGPAD TMVQYMELFN KIRKQQQVPV AGIR

UniProtKB: Mediator of RNA polymerase II transcription subunit 20

分子 #69: Mediator of RNA polymerase II transcription subunit 22

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 22; タイプ: protein_or_peptide / ID: 69 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 22.243713 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MAQQRALPQS KETLLQSYNK RLKDDIKSIM DNFTEIIKTA KIEDETQVSR ATQGEQDNYE MHVRAANIVR AGESLMKLVS DLKQFLILN DFPSVNEAID QRNQQLRTLQ EECDRKLITL RDEISIDLYE LEEEYYSSSS SLCEANDLPL CEAYGRLDLD T DSADGLSA PLLASPEPSA GPLQVAAPAH SHAGGPGPTE HA

UniProtKB: Mediator of RNA polymerase II transcription subunit 22

分子 #70: Isoform 2 of Mediator of RNA polymerase II transcription subunit 16

• 分子: 名称: Isoform 2 of Mediator of RNA polymerase II transcription subunit 16; タイプ: protein_or_peptide / ID: 70 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 93.136039 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MCDLRRPAAG GMMDLAYVCE WEKWSKSTHC PSVPLACAWS CRNLIAFTMD LRSDDQDLTR MIHILDTEHP WDLHSIPSEH HEAITCLEW DQSGSRLLSA DADGQIKCWS MADHLANSWE SSVGSLVEGD PIVALSWLHN GVKLALHVEK SGASSFGEKF S RVKFSPSL TLFGGKPMEG WIAVTVSGLV TVSLLKPSGQ VLTSTESLCR LRGRVALADI AFTGGGNIVV ATADGSSASP VQ FYKVCVS VVSEKCRIDT EILPSLFMRC TTDLNRKDKF PAITHLKFLA RDMSEQVLLC ASSQTSSIVE CWSLRKEGLP VNN IFQQIS PVVGDKQPTI LKWRILSATN DLDRVSAVAL PKLPISLTNT DLKVASDTQF YPGLGLALAF HDGSVHIVHR LSLQ TMAVF YSSAAPRPVD EPAMKRPRTA GPAVHLKAMQ LSWTSLALVG IDSHGKLSVL RLSPSMGHPL EVGLALRHLL FLLEY CMVT GYDWWDILLH VQPSMVQSLV EKLHEEYTRQ TAALQQVLST RILAMKASLC KLSPCTVTRV CDYHTKLFLI AISSTL KSL LRPHFLNTPD KSPGDRLTEI CTKITDVDID KVMINLKTEE FVLDMNTLQA LQQLLQWVGD FVLYLLASLP NQGSLLR PG HSFLRDGTSL GMLRELMVVI RIWGLLKPSC LPVYTATSDT QDSMSLLFRL LTKLWICCRD EGPASEPDEA LVDECCLL P SQLLIPSLDW LPASDGLVSR LQPKQPLRLQ FGRAPTLPGS AATLQLDGLA RAPGQPKIDH LRRLHLGACP TEECKACTR CGCVTMLKSP NRTTAVKQWE QRWIKNCLCG GLWWRVPLSY P

UniProtKB: Mediator of RNA polymerase II transcription subunit 16

分子 #71: Mediator of RNA polymerase II transcription subunit 23

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 23; タイプ: protein_or_peptide / ID: 71 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 156.652156 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

METQLQSIFE EVVKTEVIEE AFPGMFMDTP EDEKTKLISC LGAFRQFWGG LSQESHEQCI QWIVKFIHGQ HSPKRISFLY DCLAMAVET GLLPPRLVCE SLINSDTLEW ERTQLWALTF KLVRKIIGGV DYKGVRDLLK VILEKILTIP NTVSSAVVQQ L LAAREVIA YILERNACLL PAYFAVTEIR KLYPEGKLPH WLLGNLVSDF VDTFRPTARI NSICGRCSLL PVVNNSGAIC NS WKLDPAT LRFPLKGLLP YDKDLFEPQT ALLRYVLEQP YSRDMVCNML GLNKQHKQRC PVLEDQLVDL VVYAMERSET EEK FDDGGT SQLLWQHLSS QLIFFVLFQF ASFPHMVLSL HQKLAGRGLI KGRDHLMWVL LQFISGSIQK NALADFLPVM KLFD LLYPE KEYIPVPDIN KPQSTHAFAM TCIWIHLNRK AQNDNSKLQI PIPHSLRLHH EFLQQSLRNK SLQMNDYKIA LLCNA YSTN SECFTLPMGA LVETIYGNGI MRIPLPGTNC MASGSITPLP MNLLDSLTVH AKMSLIHSIA TRVIKLAHAK SSVALA PAL VETYSRLLVY MEIESLGIKG FISQLLPTVF KSHAWGILHT LLEMFSYRMH HIQPHYRVQL LSHLHTLAAV AQTNQNQ LH LCVESTALRL ITALGSSEVQ PQFTRFLSDP KTVLSAESEE LNRALILTLA RATHVTDFFT GSDSIQGTWC KDILQTIM S FTPHNWASHT LSCFPGPLQA FFKQNNVPQE SRFNLKKNVE EEYRKWKSMS NENDIITHFS MQGSPPLFLC LLWKMLLET DHINQIGYRV LERIGARALV AHVRTFADFL VYEFSTSAGG QQLNKCIEIL NDMVWKYNIV TLDRLILCLA MRSHEGNEAQ VCYFIIQLL LLKPNDFRNR VSDFVKENSP EHWLQNDWHT KHMNYHKKYP EKLYFEGLAE QVDPPVQIQS PYLPIYFGNV C LRFLPVFD IVIHRFLELL PVSKSLETLL DHLGGLYKFH DRPVTYLYNT LHYYEMHLRD RAFLKRKLVH AIIGSLKDNR PQ GWCLSDT YLKCAMNARE ENPWVPDDTY YCRLIGRLVD TMAGKSPGPF PNCDWRFNEF PNPAAHALHV TCVELMALAV SGK EVGNAL LNVVLKSQPL VPRENITAWM NAIGLIITAL PEPYWIVLHD RIVSVISSPS LTSETEWVGY PFRLFDFTAC HQSY SEMSC SYTLALAHAV WHHSSIGQLS LIPKFLTEVL LPIVKTEFQL LYVYHLVGPF LQRFQQERTR CMIEIGVAFY DMLLN VDQC STHLNYMDPI CDFLYHMKYM FTGDSVKEQV EKIICNLKPA LKLRLRFITH ISKMEPAAVP PQAMNSGSPA PQSNQV PVS LPVTQ

UniProtKB: Mediator of RNA polymerase II transcription subunit 23

分子 #72: Mediator of RNA polymerase II transcription subunit 24

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 24; タイプ: protein_or_peptide / ID: 72 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 110.430164 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MKVVNLKQAI LQAWKERWSD YQWAINMKKF FPKGATWDIL NLADALLEQA MIGPSPNPLI LSYLKYAISS QMVSYSSVLT AISKFDDFS RDLCVQALLD IMDMFCDRLS CHGKAEECIG LCRALLSALH WLLRCTAASA ERLREGLEAG TPAAGEKQLA M CLQRLEKT LSSTKNRALL HIAKLEEASS WTAIEHSLLK LGEILANLSN PQLRSQAEQC GTLIRSIPTM LSVHAEQMHK TG FPTVHAV ILLEGTMNLT GETQSLVEQL TMVKRMQHIP TPLFVLEIWK ACFVGLIESP EGTEELKWTA FTFLKIPQVL VKL KKYSHG DKDFTEDVNC AFEFLLKLTP LLDKADQRCN CDCTNFLLQE CGKQGLLSEA SVNNLMAKRK ADREHAPQQK SGEN ANIQP NIQLILRAEP TVTNILKTMD ADHSKSPEGL LGVLGHMLSG KSLDLLLAAA AATGKLKSFA RKFINLNEFT TYGSE ESTK PASVRALLFD ISFLMLCHVA QTYGSEVILS ESRTGAEVPF FETWMQTCMP EEGKILNPDH PCFRPDSTKV ESLVAL LNN SSEMKLVQMK WHEACLSISA AILEILNAWE NGVLAFESIQ KITDNIKGKV CSLAVCAVAW LVAHVRMLGL DEREKSL QM IRQLAGPLFS ENTLQFYNER VVIMNSILER MCADVLQQTA TQIKFPSTGV DTMPYWNLLP PKRPIKEVLT DIFAKVLE K GWVDSRSIHI FDTLLHMGGV YWFCNNLIKE LLKETRKEHT LRAVELLYSI FCLDMQQVTL VLLGHILPGL LTDSSKWHS LMDPPGTALA KLAVWCALSS YSSHKGQAST RQKKRHREDI EDYISLFPLD DVQPSKLMRL LSSNEDDANI LSSPTDRSMS SSLSASQLH TVNMRDPLNR VLANLFLLIS SILGSRTAGP HTQFVQWFME ECVDCLEQGG RGSVLQFMPF TTVSELVKVS A MSSPKVVL AITDLSLPLG RQVAAKAIAA L

UniProtKB: Mediator of RNA polymerase II transcription subunit 24

分子 #73: Mediator of RNA polymerase II transcription subunit 25

• 分子: 名称: Mediator of RNA polymerase II transcription subunit 25; タイプ: protein_or_peptide / ID: 73 / コピー数: 1 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 78.230344 KDa
• 組換発現: 生物種: Homo sapiens (ヒト)

配列

文字列:

MVPGSEGPAR AGSVVADVVF VIEGTANLGP YFEGLRKHYL LPAIEYFNGG PPAETDFGGD YGGTQYSLVV FNTVDCAPES YVQCHAPTS SAYEFVTWLD GIKFMGGGGE SCSLIAEGLS TALQLFDDFK KMREQIGQTH RVCLLICNSP PYLLPAVEST T YSGCTTEN LVQQIGERGI HFSIVSPRKL PALRLLFEKA APPALLEPLQ PPTDVSQDPR HMVLVRGLVL PVGGGSAPGP LQ SKQPVPL PPAAPSGATL SAAPQQPLPP VPPQYQVPGN LSAAQVAAQN AVEAAKNQKA GLGPRFSPIT PLQQAAPGVG PPF SQAPAP QLPPGPPGAP KPPPASQPSL VSTVAPGSGL APTAQPGAPS MAGTVAPGGV SGPSPAQLGA PALGGQQSVS NKLL AWSGV LEWQEKPKPA SVDANTKLTR SLPCQVYVNH GENLKTEQWP QKLIMQLIPQ QLLTTLGPLF RNSRMVQFHF TNKDL ESLK GLYRIMGNGF AGCVHFPHTA PCEVRVLMLL YSSKKKIFMG LIPYDQSGFV NGIRQVITNH KQVQQQKLEQ QQRGMG GQQ APPGLGPILE DQARPSQNLL QLRPPQPQPQ GTVGASGATG QPQPQGTAQP PPGAPQGPPG AASGPPPPGP ILRPQNP GA NPQLRSLLLN PPPPQTGVPP PQASLHHLQP PGAPALLPPP HQGLGQPQLG PPLLHPPPAQ SWPAQLPPRA PLPGQMLL S GGPRGPVPQP GLQPSVMEDD ILMDLI

UniProtKB: Mediator of RNA polymerase II transcription subunit 25

分子 #74: HISTONE H2A.Z

• 分子: 名称: HISTONE H2A.Z / タイプ: protein_or_peptide / ID: 74 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Homo sapiens (ヒト)
• 分子量: 理論値: 13.581796 KDa
• 組換発現: 生物種: Escherichia coli (大腸菌)

配列

文字列:

MAGGKAGKDS GKAKTKAVSR SQRAGLQFPV GRIHRHLKSR TTSHGRVGAT AAVYSAAILE YLTAEVLELA GNASKDLKVK RITPRHLQL AIRGDEELDS LIKATIAGGG VIPHIHKSLI GKKGQQKTV

分子 #75: Histone H2B

• 分子: 名称: Histone H2B / タイプ: protein_or_peptide / ID: 75 / コピー数: 2 / 光学異性体: LEVO
• 由来(天然): 生物種: Xenopus laevis (アフリカツメガエル)
• 分子量: 理論値: 13.979291 KDa
• 組換発現: 生物種: Escherichia coli (大腸菌)

配列

文字列:

MPEPAKSAPA PKKGSKKAVT KTQKKDGKKR RKTRKESYAI YVYKVLKQVH PDTGISSKAM SIMNSFVNDV FERIAGEASR LAHYNKRST ITSREIQTAV RLLLPGELAK HAVSEGTKAV TKYTSAK

UniProtKB: Histone H2B

分子 #78: ZINC ION

• 分子: 名称: ZINC ION / タイプ: ligand / ID: 78 / コピー数: 19 / 式: ZN
• 分子量: 理論値: 65.409 Da

分子 #79: IRON/SULFUR CLUSTER

• 分子: 名称: IRON/SULFUR CLUSTER / タイプ: ligand / ID: 79 / コピー数: 1 / 式: SF4
• 分子量: 理論値: 351.64 Da

Chemical component information

ChemComp-FS1:
IRON/SULFUR CLUSTER / 一硫化鉄

分子 #80: MAGNESIUM ION

• 分子: 名称: MAGNESIUM ION / タイプ: ligand / ID: 80 / コピー数: 1 / 式: MG
• 分子量: 理論値: 24.305 Da

実験情報

構造解析

• 手法: クライオ電子顕微鏡法
• 解析: 単粒子再構成法
• 試料の集合状態: particle

試料調製

• 緩衝液: pH: 7.9
• 凍結: 凍結剤: ETHANE

電子顕微鏡法

• 顕微鏡: FEI TITAN KRIOS
• 撮影: フィルム・検出器のモデル: GATAN K3 (6k x 4k) / 平均電子線量: 50.0 e/Ų
• 電子線: 加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
• 電子光学系: 照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELD / 最大 デフォーカス（公称値）: 2.5 µm / 最小 デフォーカス（公称値）: 1.5 µm
• 実験機器: モデル: Titan Krios / 画像提供: FEI Company

画像解析

• 初期モデル: モデルのタイプ: OTHER
• 最終 再構成: 解像度のタイプ: BY AUTHOR / 解像度: 5.04 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 26458
• 初期 角度割当: タイプ: OTHER
• 最終 角度割当: タイプ: MAXIMUM LIKELIHOOD