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- EMDB-18437: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mu... -

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Open data

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Basic information

Entry

Database: EMDB / ID: EMD-18437

Title

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4

Map data

Composite map

Sample

Complex: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4
- RNA: x 10 types
- Protein or peptide: x 76 types
Ligand: x 5 types

Keywords

Leishmania major / snoRNA / Ribosome

Function / homology

Function and homology information

ciliary transition zone / ciliary plasm / nuclear lumen / negative regulation of translational frameshifting / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / protein-RNA complex assembly / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of LSU-rRNA / translation regulator activity / rescue of stalled ribosome ...
Similarity search - Function

Ribosomal protein L14, KOW motif / : / Ribosomal protein L28e / Ribosomal protein L23 / : / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e ...Ribosomal protein L14, KOW motif / : / Ribosomal protein L28e / Ribosomal protein L23 / : / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S12e / Ribosomal protein L29e / Ribosomal L29e protein family / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S2, eukaryotic / S27a-like superfamily / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein L10e / 40S Ribosomal protein S10 / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / Ribosomal protein L44e signature. / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein L19, eukaryotic / Ribosomal protein L13e / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal protein L13e / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein S27a / : / Ribosomal protein S27a / Ribosomal protein S27a / Ribosomal protein L44e / Ribosomal protein S30 / Ribosomal protein L44 / Ribosomal protein S30 / Ribosomal protein S2, eukaryotic/archaeal / : / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein L30e signature 1. / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / Ribosomal L40e family / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / 40S ribosomal protein S4, C-terminal domain / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / 40S ribosomal protein S4 C-terminus / Ribosomal protein S3, eukaryotic/archaeal / Ribosomal_L40e / Ribosomal protein L40e / Ribosomal protein L40e superfamily / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal protein 60S L18 and 50S L18e / Ribosomal Protein L6, KOW domain / Ribosomal protein L30e signature 2. / Ribosomal protein L27e / Ribosomal protein S19e / Ribosomal protein S8e, conserved site / Ribosomal protein L27e superfamily / Ribosomal protein S19e / Ribosomal L27e protein family / Ribosomal protein S8e signature. / Ribosomal_S19e / Ribosomal protein S6, eukaryotic / Ribosomal protein L30e, conserved site / Ribosomal protein S7e / Ribosomal protein L39e, conserved site / Ribosomal protein S7e / Ribosomal protein L39e signature. / 40S ribosomal protein S1/3, eukaryotes / Ribosomal protein S19A/S15e / : / Ribosomal protein L6e / Ribosomal protein L34Ae / Ribosomal protein L34e / Ribosomal protein S17e / Ribosomal protein S17e-like superfamily / Ribosomal S17 / 60S ribosomal protein L19 / Ribosomal protein L30/YlxQ / Ribosomal protein L7A/L8 / 60S ribosomal protein L6E / 60S ribosomal protein L35 / : / Ribosomal protein L13, eukaryotic/archaeal / Ribosomal S24e conserved site
Similarity search - Domain/homology

40S ribosomal protein S7 / Putative ribosomal protein L1a / Putative 60S ribosomal protein L13 / 40S ribosomal protein S19-like protein / Ribosomal protein L37 / 60S ribosomal protein L30 / Putative 60S ribosomal protein L5 / Putative 60S ribosomal subunit protein L31 / Putative 60S ribosomal protein L27A/L29 / Putative 60S ribosomal protein L23 ...40S ribosomal protein S7 / Putative ribosomal protein L1a / Putative 60S ribosomal protein L13 / 40S ribosomal protein S19-like protein / Ribosomal protein L37 / 60S ribosomal protein L30 / Putative 60S ribosomal protein L5 / Putative 60S ribosomal subunit protein L31 / Putative 60S ribosomal protein L27A/L29 / Putative 60S ribosomal protein L23 / Putative 60S ribosomal protein L10 / Small ribosomal subunit protein eS8 / Large ribosomal subunit protein uL5 / Ubiquitin-ribosomal protein eL40 fusion protein / Putative 60S ribosomal protein L2 / Small ribosomal subunit protein eS1 / Small ribosomal subunit protein uS2 / Large ribosomal subunit protein eL22 / Putative 40S ribosomal protein S27-1 / 60S ribosomal protein L29 / 40S ribosomal protein S24 / Putative ribosomal protein L24 / Putative 40S ribosomal protein S10 / Ribosomal protein S18 / Ribosomal protein L3 / Putative 60S ribosomal protein L44 / Putative 40S ribosomal protein S13 / 40S ribosomal protein S3 / Putative 60S ribosomal protein L6 / Putative ribosomal protein L27 / 60S ribosomal protein L18a / Putative RNA binding protein / Ribosomal protein L15 / 40S ribosomal protein S30 / Activated protein kinase c receptor / Putative 40S ribosomal protein S17 / Putative ribosomal protein S29 / Putative ribosomal protein S20 / 40S ribosomal protein S14 / 40S ribosomal protein S26 / Putative 60S ribosomal protein L35 / Putative ribosomal protein L38 / Putative 40S ribosomal protein S33 / Ribosomal protein S16 / Putative 60S ribosomal protein L7 / 40S ribosomal protein S25 / Putative 60S ribosomal protein L26 / Putative 60S ribosomal protein L17 / Putative 40S ribosomal protein L14 / Putative 40S ribosomal protein S15 / 60S ribosomal protein L37a / 60S ribosomal protein L32 / Putative 40S ribosomal protein S23 / Putative 60S ribosomal protein L9 / Putative 60S Ribosomal protein L36 / Small ribosomal subunit protein uS5 / Putative 60S ribosomal protein L34 / Putative 60S ribosomal protein L39 / Putative 60S ribosomal protein L21 / Putative 60S ribosomal protein L13a / Ubiquitin-ribosomal protein eL40 fusion protein / 40S ribosomal protein S4 / 40S ribosomal protein S12 / Large ribosomal subunit protein eL18 / Putative 40S ribosomal protein S15A / Putative 60S ribosomal protein L28 / Putative 40S ribosomal protein S21 / Putative ribosomal protein l35a / Putative 40S ribosomal protein S9 / 60S ribosomal protein L7a / Putative 60S ribosomal protein L23a / Putative 60S ribosomal protein L19 / 40S ribosomal protein S5 / Small ribosomal subunit protein eS6
Similarity search - Component

Biological species

Leishmania major strain Friedlin (eukaryote)

Method

single particle reconstruction / cryo EM / Resolution: 2.43 Å

Authors

Rajan KS / Yonath A / Bashan A

Funding support

European Union, 1 items

Citation

Journal: To Be Published
Title: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4
Authors: Rajan KS / Yonath A / Bashan A

History

Deposition	Sep 12, 2023	-
Header (metadata) release	Jan 1, 2025	-
Map release	Jan 1, 2025	-
Update	Jan 1, 2025	-
Current status	Jan 1, 2025	Processing site: PDBe / Status: Released

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Structure visualization

Supplemental images	emd_18437.png

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Downloads & links

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EMDB archive

Map data	emd_18437.map.gz	62.8 MB		EMDB map data format
Header (meta data)	emd-18437-v30.xml emd-18437.xml	104.8 KB 104.8 KB	Display Display	EMDB header
FSC (resolution estimation)	emd_18437_fsc.xml	16.9 KB	Display	FSC data file
Images	emd_18437.png	111.3 KB
Filedesc metadata	emd-18437.cif.gz	20.4 KB
Others	emd_18437_additional_1.map.gz	75 MB
Archive directory	http://ftp.pdbj.org/pub/emdb/structures/EMD-18437 ftp://ftp.pdbj.org/pub/emdb/structures/EMD-18437	HTTPS FTP

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Related structure data

Related structure data	8qieMC 18514 18515 M: atomic model generated by this map C: citing same article (ref.)
Similar structure data	Similarity search - Function & homologyF&H Search Similarity search - FunctionF&H Search Similarity search - HomologyF&H Search

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Links

EMDB pages	EMDB (EBI/PDBe) / EMDataResource
Related items in Molecule of the Month	#161 - May 2013 Ricin similarity (188) #121 - Jan 2010 70S Ribosomes similarity (62) #266 - Feb 2022 Oligosaccharyltransferase similarity (85) #10 - Oct 2000 Ribosome similarity (62) #60 - Dec 2004 Ubiquitin similarity (4) #260 - Aug 2021 Ribonuclease P similarity (3) #104 - Aug 2008 Selenocysteine Synthase similarity (1)

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Map

File

Download / File: emd_18437.map.gz / Format: CCP4 / Size: 421.9 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)

Annotation

Composite map

Projections & slices

Image control

Size
Brightness
Contrast
Others	InvertY flip

Axes	Z (Sec.)	Y (Row.)	X (Col.)
	0.82 Å/pix. x 480 pix. = 395.76 Å	0.82 Å/pix. x 480 pix. = 395.76 Å	0.82 Å/pix. x 480 pix. = 395.76 Å
Surface
Projections
Slices (1/3)
Slices (1/2)
Slices (2/3)

Images are generated by Spider.

Voxel size

X=Y=Z: 0.8245 Å

Density

Histogram

Histogram (log scale)

Contour Level	By AUTHOR: 0.008
Minimum - Maximum	-0.08657078 - 0.18132593
Average (Standard dev.)	0.000739032 (±0.005374123)

Symmetry

Space group: 1

Details

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Supplemental data

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Additional map: Consensus map

File

emd_18437_additional_1.map

Annotation

Consensus map

Projections & Slices

Axes	Z	Y	X
Projections
Slices (1/2)

Density Histograms

Histogram

Histogram (log scale)

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Sample components

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Entire : CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mu...

Entire	Name: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4
Components	Complex: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4 RNA: LSUa_rRNA_chain_1 RNA: LSUb_rRNA_chain_2 RNA: SR1_chain_3 RNA: SR2_chain_4 RNA: SR4_chain_5 RNA: SR6_chain_6 RNA: 5.8S_rRNA_chain_7 RNA: 5S_rRNA_chain_8 Protein or peptide: Putative 60S ribosomal protein L2 Protein or peptide: Putative ribosomal protein L3 Protein or peptide: Putative ribosomal protein L1a Protein or peptide: 60S ribosomal protein L11 Protein or peptide: Putative 60S ribosomal protein L9 Protein or peptide: Putative 60S ribosomal protein L6 Protein or peptide: 60S ribosomal protein L7a Protein or peptide: Putative 60S ribosomal protein L13a Protein or peptide: Putative 60S ribosomal protein L13 Protein or peptide: Putative 60S ribosomal protein L23 Protein or peptide: Putative 40S ribosomal protein L14 Protein or peptide: Putative 60S ribosomal protein L27A/L29 Protein or peptide: Ribosomal protein L15 Protein or peptide: Putative 60S ribosomal protein L10 Protein or peptide: Putative 60S ribosomal protein L5 Protein or peptide: 60S ribosomal protein L18 Protein or peptide: Putative 60S ribosomal protein L19 Protein or peptide: 60S ribosomal protein L18a Protein or peptide: Putative 60S ribosomal protein L21 RNA: SSU_rRNA_chain_S1 RNA: E-site_tRNA_chain_S4 Protein or peptide: 40S ribosomal protein S3a Protein or peptide: 40S ribosomal protein SA Protein or peptide: Putative 40S ribosomal protein S3 Protein or peptide: Putative 40S ribosomal protein S9 Protein or peptide: 40S ribosomal protein S4 Protein or peptide: 40S ribosomal protein S2 Protein or peptide: 40S ribosomal protein S6 Protein or peptide: 40S ribosomal protein S5 Protein or peptide: 40S ribosomal protein S7 Protein or peptide: Putative 40S ribosomal protein S15A Protein or peptide: 40S ribosomal protein S8 Protein or peptide: Putative 40S ribosomal protein S16 Protein or peptide: Putative ribosomal protein S20 Protein or peptide: Putative 40S ribosomal protein S10 Protein or peptide: 40S ribosomal protein S14 Protein or peptide: Putative 40S ribosomal protein S23 Protein or peptide: 40S ribosomal protein S12 Protein or peptide: Putative 40S ribosomal protein S18 Protein or peptide: Putative ribosomal protein S29 Protein or peptide: Putative 40S ribosomal protein S13 Protein or peptide: Putative 40S ribosomal protein S11 Protein or peptide: Putative 40S ribosomal protein S17 Protein or peptide: Putative 40S ribosomal protein S15 Protein or peptide: 40S ribosomal protein S19-like protein Protein or peptide: Putative 40S ribosomal protein S21 Protein or peptide: 40S ribosomal protein S24 Protein or peptide: 40S ribosomal protein S25 Protein or peptide: 40S ribosomal protein S26 Protein or peptide: Putative 40S ribosomal protein S27-1 Protein or peptide: Putative 40S ribosomal protein S33 Protein or peptide: 40S ribosomal protein S30 Protein or peptide: Ubiquitin-60S ribosomal protein L40 Protein or peptide: Guanine nucleotide-binding protein subunit beta-like protein Protein or peptide: Putative RNA binding protein Protein or peptide: Putative 60S ribosomal protein L17 Protein or peptide: Putative 60S ribosomal protein L22 Protein or peptide: Putative 60S ribosomal protein L23a Protein or peptide: Putative 60S ribosomal protein L26 Protein or peptide: Putative ribosomal protein L24 Protein or peptide: 60S ribosomal protein L27 Protein or peptide: Putative 60S ribosomal protein L28 Protein or peptide: Putative 60S ribosomal protein L35 Protein or peptide: 60S ribosomal protein L29 Protein or peptide: Putative 60S ribosomal protein L7 Protein or peptide: 60S ribosomal protein L30 Protein or peptide: Putative 60S ribosomal subunit protein L31 Protein or peptide: 60S ribosomal protein L32 Protein or peptide: Putative ribosomal protein l35a Protein or peptide: Putative 60S ribosomal protein L34 Protein or peptide: Putative 60S Ribosomal protein L36 Protein or peptide: Ribosomal protein L37 Protein or peptide: Putative ribosomal protein L38 Protein or peptide: Putative 60S ribosomal protein L39 Protein or peptide: Ubiquitin-60S ribosomal protein L40 Protein or peptide: 60S ribosomal protein L41 Protein or peptide: 60S ribosomal protein L37a Protein or peptide: Putative 60S ribosomal protein L44 Ligand: MAGNESIUM ION Ligand: SODIUM ION Ligand: POTASSIUM ION Ligand: ZINC ION Ligand: water

Entire

Name: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4

Components

Complex: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4
- RNA: LSUa_rRNA_chain_1
- RNA: LSUb_rRNA_chain_2
- RNA: SR1_chain_3
- RNA: SR2_chain_4
- RNA: SR4_chain_5
- RNA: SR6_chain_6
- RNA: 5.8S_rRNA_chain_7
- RNA: 5S_rRNA_chain_8
- Protein or peptide: Putative 60S ribosomal protein L2
- Protein or peptide: Putative ribosomal protein L3
- Protein or peptide: Putative ribosomal protein L1a
- Protein or peptide: 60S ribosomal protein L11
- Protein or peptide: Putative 60S ribosomal protein L9
- Protein or peptide: Putative 60S ribosomal protein L6
- Protein or peptide: 60S ribosomal protein L7a
- Protein or peptide: Putative 60S ribosomal protein L13a
- Protein or peptide: Putative 60S ribosomal protein L13
- Protein or peptide: Putative 60S ribosomal protein L23
- Protein or peptide: Putative 40S ribosomal protein L14
- Protein or peptide: Putative 60S ribosomal protein L27A/L29
- Protein or peptide: Ribosomal protein L15
- Protein or peptide: Putative 60S ribosomal protein L10
- Protein or peptide: Putative 60S ribosomal protein L5
- Protein or peptide: 60S ribosomal protein L18
- Protein or peptide: Putative 60S ribosomal protein L19
- Protein or peptide: 60S ribosomal protein L18a
- Protein or peptide: Putative 60S ribosomal protein L21
- RNA: SSU_rRNA_chain_S1
- RNA: E-site_tRNA_chain_S4
- Protein or peptide: 40S ribosomal protein S3a
- Protein or peptide: 40S ribosomal protein SA
- Protein or peptide: Putative 40S ribosomal protein S3
- Protein or peptide: Putative 40S ribosomal protein S9
- Protein or peptide: 40S ribosomal protein S4
- Protein or peptide: 40S ribosomal protein S2
- Protein or peptide: 40S ribosomal protein S6
- Protein or peptide: 40S ribosomal protein S5
- Protein or peptide: 40S ribosomal protein S7
- Protein or peptide: Putative 40S ribosomal protein S15A
- Protein or peptide: 40S ribosomal protein S8
- Protein or peptide: Putative 40S ribosomal protein S16
- Protein or peptide: Putative ribosomal protein S20
- Protein or peptide: Putative 40S ribosomal protein S10
- Protein or peptide: 40S ribosomal protein S14
- Protein or peptide: Putative 40S ribosomal protein S23
- Protein or peptide: 40S ribosomal protein S12
- Protein or peptide: Putative 40S ribosomal protein S18
- Protein or peptide: Putative ribosomal protein S29
- Protein or peptide: Putative 40S ribosomal protein S13
- Protein or peptide: Putative 40S ribosomal protein S11
- Protein or peptide: Putative 40S ribosomal protein S17
- Protein or peptide: Putative 40S ribosomal protein S15
- Protein or peptide: 40S ribosomal protein S19-like protein
- Protein or peptide: Putative 40S ribosomal protein S21
- Protein or peptide: 40S ribosomal protein S24
- Protein or peptide: 40S ribosomal protein S25
- Protein or peptide: 40S ribosomal protein S26
- Protein or peptide: Putative 40S ribosomal protein S27-1
- Protein or peptide: Putative 40S ribosomal protein S33
- Protein or peptide: 40S ribosomal protein S30
- Protein or peptide: Ubiquitin-60S ribosomal protein L40
- Protein or peptide: Guanine nucleotide-binding protein subunit beta-like protein
- Protein or peptide: Putative RNA binding protein
- Protein or peptide: Putative 60S ribosomal protein L17
- Protein or peptide: Putative 60S ribosomal protein L22
- Protein or peptide: Putative 60S ribosomal protein L23a
- Protein or peptide: Putative 60S ribosomal protein L26
- Protein or peptide: Putative ribosomal protein L24
- Protein or peptide: 60S ribosomal protein L27
- Protein or peptide: Putative 60S ribosomal protein L28
- Protein or peptide: Putative 60S ribosomal protein L35
- Protein or peptide: 60S ribosomal protein L29
- Protein or peptide: Putative 60S ribosomal protein L7
- Protein or peptide: 60S ribosomal protein L30
- Protein or peptide: Putative 60S ribosomal subunit protein L31
- Protein or peptide: 60S ribosomal protein L32
- Protein or peptide: Putative ribosomal protein l35a
- Protein or peptide: Putative 60S ribosomal protein L34
- Protein or peptide: Putative 60S Ribosomal protein L36
- Protein or peptide: Ribosomal protein L37
- Protein or peptide: Putative ribosomal protein L38
- Protein or peptide: Putative 60S ribosomal protein L39
- Protein or peptide: Ubiquitin-60S ribosomal protein L40
- Protein or peptide: 60S ribosomal protein L41
- Protein or peptide: 60S ribosomal protein L37a
- Protein or peptide: Putative 60S ribosomal protein L44
Ligand: MAGNESIUM ION
Ligand: SODIUM ION
Ligand: POTASSIUM ION
Ligand: ZINC ION
Ligand: water

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Supramolecule #1: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mu...

Supramolecule	Name: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4 type: complex / ID: 1 / Parent: 0 / Macromolecule list: #1-#86 Details: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mutant snoRNA overexpression, class 4
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)

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Macromolecule #1: LSUa_rRNA_chain_1

Macromolecule	Name: LSUa_rRNA_chain_1 / type: rna / ID: 1 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 577.069562 KDa
Sequence	String: ACAGACCUGA GUGUGGCAGG ACUACCCGCC GAACUUAAGC AUAUUACUCA GCGGAGGAAA AGAAAACAAC CGUGAUUCUC UCAGUGAGC GGCGAGCGAA GAGGGAACGA ACUCGUUGCC GAAUCGGGUC UUACAAGGCC UUGAGUUGUG GCACAAAUAU C AUUGUGUG ...String: ACAGACCUGA GUGUGGCAGG ACUACCCGCC GAACUUAAGC AUAUUACUCA GCGGAGGAAA AGAAAACAAC CGUGAUUCUC UCAGUGAGC GGCGAGCGAA GAGGGAACGA ACUCGUUGCC GAAUCGGGUC UUACAAGGCC UUGAGUUGUG GCACAAAUAU C AUUGUGUG GUUGGUGCAG GAGUGGCGAA AUUCAAGCGA AAAGCAAACC CGUUGCUGAA UACAACCCUU CAUGUG(A2M)G U A(PSU)UGAGCCAA AGAAGGUGUU AGCCCAUUGA GCCAUAAACC UGAGCGCCUC AUGAACUGUA UUAAGCG(A2M)GU A GCACUGUU UGGGAAUGCA GUGUCAAGUU GGCAGGUAUU UGUCUGCCAA AGUUAAAUAC AGAGUAGGAA GACCGAUAGC GA ACAAGUA GCGUGAGCGA A(A2M)GUUUGAAA AGCACU(PSU)UGG AAAGAGAGUG AAAUAGAACC UGAAGUCGUG ACAAA GACA AUGGAAGUAC CUCCAUUUCA ACGGCCAGAA CCAGCCCUAC UGCAUUAUCC UGUCGGGGAU CAAAAUCCGG CGGGCA ACG AAGUGCAAGA AUCUUGGGUC UUGGUGAAAU GAGCGGAGUA UUUGAGCUGC GCACGGCGCA AGCCGCACGC ACUGGUU UC UUCUCCGUGA UGCUCCAUGU UGGCGAUGGA AAUGGGGUGC CCCCACCCG(PSU) CUUG(1MA)(A2M)AC(A2M)C GG ACCAAGG AGU(OMC)A(A2M)ACAG ACGCGCAAGG GAGGAGAUAU GGUUGCCAGU ACUUCUCUCG UACUGAAAGG GAGAU GCAA AAUGCAUCUG UGGUGUGCAC ACGUCAAAUC CGUUUGAUUU GCCCAACACC GACCGGCCCU CCGUGGGUUG CGUUGG AGU GUGCC(OMU)G(OMU)UU GGACCC(OMG)A(A2M)A GGUGGUGAAC UAUGCCUGAA CAAGGUGAAG CCCGGGGAAA C CCAGGUGG AGGCCUGUAG CGAUGCUG(A2M)C GUGCAAAUCG C(PSU)CGUAUGAU UUGGGU(A2M)UCG (OMG)AGCGA AAG ACUCAUCGAA CCACCUAGUA GCUGGUUCAC AUCGAAGUUU CC(OMC)(PSU)CAGGA(PSU) AGCUGGUGCU AGUAG AAGU AU(PSU)GUGCGGU AAAGCAAAUG AUUAGAGGCA UUGGUGUUCU UAGAAUAUCG ACCUAUUCUC AAACUUUAAA (OMU)GUGCAAAC AAACCGUGCC UUAGCCAACU GCAAGGCCGG AAAGAAAAGA AUUAGAGGCA CCAAG(PSU)GGGC CUU CU(PSU)CGG UAAGC(OMG)GAGC AGGCGAUGCG GAAUGAACCG CUUAGGGAUA UGUGGCGUCA AAACUUAUGG GCUCAU UCU CGAUACGUGA AAAGGGUGUU GGUGGAUAUG GACAGUUGGA CGGUGGCCAU GGAAGUCGGC AUCCGCUAAG GAGUGUG UA ACAACUCACC AACCGAAUCC ACCGGCCCCG AAAAUGGA(OMU)G ACGCUUAAGC CCAAUUAGUG AUUGCCCAU(PSU) AUUCCUUUG GUAAGGGCGG AAACAAAUCU UGGAGAAAGU GUAGCCCUUC CGAUGUAGAU GUGGCCUGGA GGUUAGGACG A AGCUUAUG GCGUGAGCCU AAGAUGGACC GGCCUCUAGU GCA(OMG)AU(OMC)(PSU)UG GU(PSU)GGCGU(A2M) (OMG)CAAAGAUCU AACGGAGAUA UACUCAACAU GCAACGUUGG AUACUGGAGC GGGGAAGGAU UUCGUGCCAA CGGCAC UCG UACACGA(OMG)UU GUUCGGAAAC UGAGCACAAC GUUAUAUCGU (OMU)UUGU(PSU)AGGA AAGUGAAGGU GUGUC GGCG GCAGCUGCUC UCGGGUAGCU GUUCGACUGG CCAUAACUGA AAAGGGGCAA CAGAGAACCU GGGAUUAUAU UCCAAA AAG AAAUUGCAUG UGGGAA

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Macromolecule #2: LSUb_rRNA_chain_2

Macromolecule	Name: LSUb_rRNA_chain_2 / type: rna / ID: 2 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 492.501781 KDa
Sequence	String: UCCCAACUGC AGACCGUACU CAUCACCGCA UCAGGUCCCC AAGCAUAGAA UGCUC(OMU)GGUA CAUAGAGAAA (OMG)G (OMU)ACAC(PSU)C AGGGAAGUCG GCAAA(A2M)UAGA UGCGUAAGUU CGCAAGAAGC AU(PSU)GGCUCUG AGGGCAA AG UCAGAGAAAA ...String: UCCCAACUGC AGACCGUACU CAUCACCGCA UCAGGUCCCC AAGCAUAGAA UGCUC(OMU)GGUA CAUAGAGAAA (OMG)G (OMU)ACAC(PSU)C AGGGAAGUCG GCAAA(A2M)UAGA UGCGUAAGUU CGCAAGAAGC AU(PSU)GGCUCUG AGGGCAA AG UCAGAGAAAA CCGGAAGGCC AGUGUCCUCU CGCAUGCAGC CGUUCUUCAG AUGUUGUUUU GGCGCUCGCC GCCUUAGC A CGCUGAUAGC GACUGUACUG UCGUCUGUGA AGGCUACCUU CCCGAGGCGU CGUAACCCGG CGUCUCACUC UGGCACGGG CCGGUCUUGG CGGGUUCACG CUCGUCUUGU GCCGCGUCCC ACAAAUUGCC AACUCAGAAC UG(OMC)UUACGGC GGGGAA UCC AACUGU(A2M)UAA UUAAAACAUA GGUUUGUGAU GCAUCCAAGU GGUGUAUAUC GCAAACUGAU U(PSU)CUGCC (OMC)A GUGCUCUGAA UGUCAACGUG ACGAGAU(PSU)CA CCGACGCGCG GGUAAACGGC GGGAGUAACU AUGAC(PSU) C(PSU)C UUAAGGUAGC (5MC)AA(A2M)UGCCUC (OMG)UCUUCCAAU UAGAGACGCG CAUGAA(OMU)GGA UUAAUG (A2M)G(A2M) UUCCCUCUGU (OMC)CCGAGUU(A2M)C (PSU)AUC(PSU)AGCGA A(A2M)CGACAGUC AAGGGAACG GACU(PSU)G(A2M)AGG GCUAAGCGG(OMG) GAAAGAAGAC CCU(OMG)UUGAGU (PSU)UGAC(OMU)CCAG UCUGGC UCU GUGCGGCGAC AUCUGAGGUG UAGUAUAGGU GGAAGCGCAA GCGCAAAUGA AAUACCACCA CUCGGAACGU UGCUUCA CU UAUCGAAUGA AGAGACCAAU GGGUUUAGCG UAGUCUUCGG GCUAUGCACC GUCUAGGUUU GGGAGUAAUU UUAUGGCG G UAACCCCGUC CCCACGGGAA AGGGUGGUGU GCUUUUUCUG CGUGCGUCUU CACGGGCGUC GCGCGGGCCC CGCUCUUUU UUAUUGCGUU UCCUUCGGGG GGCGUGACUU GUGGGUACCC AACCGUGCUG UAAACUGAAC CAACGGGAUU GCCUCGUGCA GUUCCGGAG UCUUGUUUCG AGACAUCUGC CAGAUGGGGA GUUUGGCUG(OMG) GGCGGCAUAU C(PSU)G(PSU)UACAC GACAACGCAG G(OMU)(OMG)UCCUAAG GCGAGCUCAG UGGGAACAGA AAUCUCACGU AGAACACAAG CGUAAAAGCU UG CUUGAU(PSU) AACGAUUUCC AGUA(OMC)GAAUC GAGACUGCGA AAGCAAGGCC (A2M)GCGAUCCU(PSU) UGCGAAG AA UAGGAAAUAU GAACAAAUCA UACCA(OMG)A(OMG)GU GUCAGAAUAA UUAC(OMC)ACAG(OMG) GAUAACUGGC (PSU)(PSU)GUGGCGG CCAAGCGUUC AUAGCGACGU CGCUUUUUGA (PSU)CCUU(5MC)GAUG UCGG(OMC)(PSU)C UU CCUAACCUAG CGCCGCAGAA GACGCUAAGG GU(PSU)GGAU(OMU)(OMG)(PSU) UCACCCACUG (A2M)CAGGGAA C G(PSU)G(A2M)GCUGGG UUUAGA(OMC)CGU CG(PSU)GAGACAG GU(PSU)GGUUU(OMU)A CCCUACUUAG CUGGA AAUU GCGAGAAAAA GAUUAUCCGU GCAAAGCGGA CGUCGGGUCG UUCUUGGGCC UGGCGAGCGG UGGGUAGUAC AUGGUA CGC UCAUCACC

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Macromolecule #3: SR1_chain_3

Macromolecule	Name: SR1_chain_3 / type: rna / ID: 3 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 69.146633 KDa
Sequence	String: UAUUAGUGGU AA(OMU)GCGAAAC ACUUGCCAGG UAACAAAUCA AUCCUCCCAC GGUGAGCUUU CUUUUCACCA UAAUCC ACA UCUCCGGCUU UGCUGGGGCU UGGGCCUUUU UACUUCUCGC GUUGUUCGGA GCGGGGGCUC AAGAUUGAAA AAUGCAG CU CUCCCUACGU ...String: UAUUAGUGGU AA(OMU)GCGAAAC ACUUGCCAGG UAACAAAUCA AUCCUCCCAC GGUGAGCUUU CUUUUCACCA UAAUCC ACA UCUCCGGCUU UGCUGGGGCU UGGGCCUUUU UACUUCUCGC GUUGUUCGGA GCGGGGGCUC AAGAUUGAAA AAUGCAG CU CUCCCUACGU ACUGUCAUUG UUGUGAGUUC UGCGCAUUAA AGCAAAAACC UGGGGUGU GENBANK: GENBANK: FR796423.1

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Macromolecule #4: SR2_chain_4

Macromolecule	Name: SR2_chain_4 / type: rna / ID: 4 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 59.466293 KDa
Sequence	String: GUGGGAUUGU GAAGGGAUCU CGCAGGUAUC GUGAGGGAAG UAUGGGGUAG UACGAGAGGA ACUCCCAUGC CGU(OMG)CC UCU AGUUUCUGGG GUUUGUCGAA CGGCAAGUGC CCCGAAGCCA UCGCACGGUG GUUCUCGGCU GAACGCCUCU AAGCCAG AA GCCAAUCCCA AGACCAGAUG CCCACU

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Macromolecule #5: SR4_chain_5

Macromolecule	Name: SR4_chain_5 / type: rna / ID: 5 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 43.48177 KDa
Sequence	String: UUACGUCCCU CUCCAAACGA GAGAACAUGC AUGGGCUGGC AUGAGCGGCA UGCUUCACUU CGGUGGGGCU CGAGGGGCAU UUACGUCCC GAGGCGCUGA ACCUUGAGGC CUGAAAUUUC AUGCUCAGGG ACACUA GENBANK: GENBANK: FR796423.1

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Macromolecule #6: SR6_chain_6

Macromolecule	Name: SR6_chain_6 / type: rna / ID: 6 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 23.336938 KDa
Sequence	String: UCAUCGAAUC GCCACCUACA AGACUGGAGC UUGCUCCCUC GAAGGCGCCA AGUAUAUUCA UGAUCACAAG ACA GENBANK: GENBANK: FR796423.1

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Macromolecule #7: 5.8S_rRNA_chain_7

Macromolecule	Name: 5.8S_rRNA_chain_7 / type: rna / ID: 7 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 54.98957 KDa
Sequence	String: AACGUG(OMU)CGC GAUGGAUGAC UUGGCUUCCU AUUUCGUUGA AG(A2M)ACGCAGU AAAGUGCGAU AAGUGGUA (PSU) CAAU(PSU)(OMG)CAGA AUCAUUCAAU UACCGAAUCU UUGAACGCAA ACGGCGCAUG GGAGAAGCUC UAUUGUG UC AUCCCCGUGC ...String: AACGUG(OMU)CGC GAUGGAUGAC UUGGCUUCCU AUUUCGUUGA AG(A2M)ACGCAGU AAAGUGCGAU AAGUGGUA (PSU) CAAU(PSU)(OMG)CAGA AUCAUUCAAU UACCGAAUCU UUGAACGCAA ACGGCGCAUG GGAGAAGCUC UAUUGUG UC AUCCCCGUGC AUGCCAUAUU CUC(A2M)GUGUCG AAC GENBANK: GENBANK: XR_002460814.1

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Macromolecule #8: 5S_rRNA_chain_8

Macromolecule	Name: 5S_rRNA_chain_8 / type: rna / ID: 8 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 39.450398 KDa
Sequence	String: CUUCGAGUAC GACCACACUU GAGUGAAAAC ACCAUAUCCC GUCCGAUUUG UGAAGUUAAG CACUCACAGG CUCAGUUAGU ACUGAGGUC AGUGAUGACU CGGGAACCCU GAGUGCCGUA CUCC GENBANK: GENBANK: FR796407.1

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Macromolecule #28: SSU_rRNA_chain_S1

Macromolecule	Name: SSU_rRNA_chain_S1 / type: rna / ID: 28 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 710.628688 KDa
Sequence	String: GAUCUGG(OMU)UG A(PSU)UCUGC(OMC)AG UAGUCAUA(OMU)G CU(PSU)GUUU(OMC)AA GGACUUAGCC AUGCAU GCC UCAGAAUCAC UGCAUUUGCA GGAAUCUGCG CAUGGCUC(A2M)U UAAA(PSU)CAGAC GUAAUCUGCC GCAAAAAUC UUGCGGUUUC ...String: GAUCUGG(OMU)UG A(PSU)UCUGC(OMC)AG UAGUCAUA(OMU)G CU(PSU)GUUU(OMC)AA GGACUUAGCC AUGCAU GCC UCAGAAUCAC UGCAUUUGCA GGAAUCUGCG CAUGGCUC(A2M)U UAAA(PSU)CAGAC GUAAUCUGCC GCAAAAAUC UUGCGGUUUC CGCAAAAUUG GAUAACUUGG CGAAACGCCA AGCUAAUACA UGAACCAACC GGGUGUUCUC CACUCCAGAC GGUGGGCAA CCAUCGUCGU GAGACGCCCA GCGAAUGAAU GACAGUAAAA CCAAUGCCUU CACUGGCAGU AACACCCAGC A GUGUUGAC UCAAUUCAUU CCGUGCGAAA GCCGGCUUGU UCCGGCGUCU UUUGACGAAC AACUGCCCUA UCAGCUGGUG AU GGCCGUG UAGUGGACUG CCAUGGCGUU GACGGGAGCG GGGGAUUAGG GUUCGAUUCC GGAGAGGGAG CCUGAGAAAU AGC UACCAC (PSU)UCUACGGAG GGCAGCAGGC GCGC(A2M)AAUUG CCCAAUGUCA AAACAAAACG AUGAGGC(A2M)GC GA AAAGAAA UAGAGUUGUC AGUCCAUUUG GAUUGUCAUU UCAAUGGGGG AUAUUUAAAC CCAUCCAAUA UCGAGUAACA AUU GGA(OMG)GA CAAG(PSU)C(PSU)GGU GCCAGCACCC GCGGUAAUUC CAGCUCCAAA AGCGUAUAUU AAUGCUGU (OMU) GCUGUU(A2M)AAG GGUUCGUAGU UGAACUGUGG GCUGUGCAGG UUUGUUCCUG GUCGUCCCGU CCAUGUCGGA U UUGGUGAC CCAGGCCCUU GCAGCCCGUG AACAUUCAAA GAAACAAGAA ACACGGGAGU GGGUCCUUUC CUGAUUUACG CA UGUCAUG CAUGCCAGGG GGCGUCCGUG AUUUUUUACU GUGACUAAAG AAGCGUGACU AAAGCAGUCA UUUGACUUGA AUU AGAAAG CAUGGGAUAA CAAAGGAGCA GCCUCUAGGC UACCGUUUCG GCUUUUGUUG UUUUUAAAGG UCUAUUGGAG AUUA UGGAG CUGUGCGACA AAUGCUUUCC CAUCGCAACU UCGGUUCGGU GUGUGGCGCC UUUGAGGGGU UUAGUGCGUC CGGUG CGAG CUCCGGUUCG UCCGGCCGUA ACGCCUUUUC AACUCACGGC CUCUAGGAAU GAAGGAGGGU AGUUCGGGGG AGAACG UAC UGGGGCGUCA GAGGUGAAAU (PSU)CUUAGACCG CACCAAGACG AACUACAGCG AAGGCA(PSU)UCU UCAAGGAUA CCUUCCUCAA UCAAGAACCA AAGUGUGGAG AUCGAAGAUG A(PSU)UAGAAACC AUUGUAGUCC ACACUGCAAA CGAUGA CAC CCAUGAAUUG GGGAUCUUAU GGGCCGGCCU GCGGCAGGGU UUACCCUGUG UCAGCACCGC GCCCGCUUUU ACCAACU UA CGUAUCUUUU CUAUUCGGCC UUUACCGGCC ACCCACGGGA AUAUCCUCAG CACGUUUUCU GUUUUUUCAC GCGAAAGC U UUGAGGUUAC AGUCUCAGGG GGGAGUACGU UCGCAA(OMG)AGU GAAACUUAAA GAAAUUGACG GAAUGGCACC ACAAG ACGU GGAGCGUGCG GU(PSU)UAAUU(PSU)G AC(B8N)(5MC)AACAC(OMG) GGGAACUUUA CCAGA(PSU)CCGG AC AGGAUGA GGAUUGACAG AUUGAGUGUU CUUUCUCGAU UCCCUGAAUG G(OMU)G(OMG)UGCAUG GCCGCUUAUG GUCGG UG(OMG)A GUGAUUUG(PSU)U UGGUUGAUUC CGUCAACGGA CGAGAUCCAA GCUGCCCAGU AGAAUUCAGA AUUGCCCA U AGGAUAGCAA ACUCAUCGGC GGGUUUUACC CAACGGUGGG CCGCAUUCGG UCGAAUUCUU CUCUGCGGGA UUCCUUUGU AAUUGCACAA GGUGAAAUUU UGGGCAACAG CA(OMG)GUC(OMU)GUG AUGC(PSU)CCUCA AUGUUCUGGG CGACACGC (OMG) (OMC)ACUACAAUG UCA(OMG)UGAGAA CAAGAAAAAC GACUUUUGUC GAACCUACUU GAUCAAAAGA GUGGGGA AA CCCCGGAAUC ACAUAGACCC ACUUGGGACC GAGGAUUGCA AUUA(OMU)UGGUC GCGCAACGAG (7MG)AAUGUCUCG UAGGCGCAG CUCAUCA(A2M)AC UGUGCCGAUU ACGUCCCUGC CA(PSU)U(PSU)GUACA CACCGCC(5MC)GU CGUUG UUUC CGAUGAUGGU GCAAUACAGG UGAUCGGACA GGCGGUGUUU UAUCCGCCCG AAAGUUCACC GAUAUUU(OMC)UU CA AUAGAG(OMG) AAGCAAAAGU CGUAACAAGG UAGCUGUAGG GG(MA6)(MA6)CCUGCA GCUGGGACAU (PSU)UU

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Macromolecule #29: E-site_tRNA_chain_S4

Macromolecule	Name: E-site_tRNA_chain_S4 / type: rna / ID: 29 / Number of copies: 1
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 24.485539 KDa
Sequence	String: GCGCGGAUAG CUCAGUCGGU AGAGCAGGGG AUUGAAAAUC CCCGUGUCCU UGGUUCGAUU CCGAGUCCGC GCACCA

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Macromolecule #9: Putative 60S ribosomal protein L2

Macromolecule	Name: Putative 60S ribosomal protein L2 / type: protein_or_peptide / ID: 9 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 28.331891 KDa
Sequence	String: MGKTVLSCRK GNGSVYQVHG HKRLGPAKLR ILDYAERHGY MRGVVKSIEH EAGRGAALAR VEFRHPYKFR RVKELMVAPE GMFTGQSVF CGQKAPLAIG NVLPLGQITE GCIVCNVEAK PGDRGTLARA SGDYCIIISH NHETGRTRLK LPSGQKKSVP S TSRAMIGI ...String: MGKTVLSCRK GNGSVYQVHG HKRLGPAKLR ILDYAERHGY MRGVVKSIEH EAGRGAALAR VEFRHPYKFR RVKELMVAPE GMFTGQSVF CGQKAPLAIG NVLPLGQITE GCIVCNVEAK PGDRGTLARA SGDYCIIISH NHETGRTRLK LPSGQKKSVP S TSRAMIGI ISGGGRIEKP VLKAGNSFYR FRGKRNCWPK VRGVARNPVE HPHGGGNHQH IGHPSTVSRH SPPGQKVGLI AA RRTGRIR GGKAVKGAWH PEE UniProtKB: Putative 60S ribosomal protein L2

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Macromolecule #10: Putative ribosomal protein L3

Macromolecule	Name: Putative ribosomal protein L3 / type: protein_or_peptide / ID: 10 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 47.59366 KDa
Sequence	String: MSHCKFEHPR HGHLGFLPRK RSRQIRGRAR AFPKDDATQK PHLTSFMVFK AGMTHIVRDV DRPGSKVNKK EVVEPVTILE APPMVIVGI VGYRQTPVGL KTIGTVWAHH TSVEFRRRYY KNWKQSAQLA FSRQKQFANT KEGKVAEART LNAFAKKASV I RVIAHTQL ...String: MSHCKFEHPR HGHLGFLPRK RSRQIRGRAR AFPKDDATQK PHLTSFMVFK AGMTHIVRDV DRPGSKVNKK EVVEPVTILE APPMVIVGI VGYRQTPVGL KTIGTVWAHH TSVEFRRRYY KNWKQSAQLA FSRQKQFANT KEGKVAEART LNAFAKKASV I RVIAHTQL RKLRNHRVGV KKAHVQEIQV NGGSVAAKIA LAKSLLEKEV RVDSVFQQSE ACDVCSVTKG HGTEGVVKRW GV ACLPRKT HRGLRKVACI GAWHPARVMY TVARAGQHGY HHRTQLNKKI YQIGRSVAVE PNQATTTYDL TAKTITPMGG FVG YGTVRN DYVMLKGSVS GPRRRVMTLR RPMAPQTSRQ LKEKIVLKFI DTSSKIGHGR FQTKKEKNQW FGPLKKDRIR REER LRKER AARAVERKAK AAKK UniProtKB: Ribosomal protein L3

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Macromolecule #11: Putative ribosomal protein L1a

Macromolecule	Name: Putative ribosomal protein L1a / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 41.096855 KDa
Sequence	String: MSARPSVSVY SASSDSVVGT CPLPAVFTAP IRSDIVKFVH TNMAKNSRQA YAVNRLSGMN HSAHSWGTGR AVARIPRISG GGTSTSGAG AFGNMCRGGR MFAPTKIFRR WHRKINLHQK RFAVVSALAA SSVPSLVMSR GHQIGNVPEV PLVVEDSIQG Y EKTKEAMA ...String: MSARPSVSVY SASSDSVVGT CPLPAVFTAP IRSDIVKFVH TNMAKNSRQA YAVNRLSGMN HSAHSWGTGR AVARIPRISG GGTSTSGAG AFGNMCRGGR MFAPTKIFRR WHRKINLHQK RFAVVSALAA SSVPSLVMSR GHQIGNVPEV PLVVEDSIQG Y EKTKEAMA FLKAIAAIDD VNRVNDSREI RAGRGKMRNR RYVARRGPML VMPNNKGTRA FRNIFGLDLA NVSALNLLHL AP GGHVGRF VIWTQSAFEQ LDKIFGTFTE ASAVKKGFTL PAPMLTNTDV TRIMQSEEVR RVLKPKKLQA KKASRFQTPT NGM KNRRLR LRLNPYVKRE TAAAKGMRNV ANRDARRKAK LARVTKAKKA ATKSAKQ UniProtKB: Putative ribosomal protein L1a

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Macromolecule #12: 60S ribosomal protein L11

Macromolecule	Name: 60S ribosomal protein L11 / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 21.694502 KDa
Sequence	String: MVAESKAANP MREIVVKKLC INICVGESGD RLTRASKVLE QLCEQTPVLS RARLTVRTFG IRRNEKIAVH CTVRGKKAEE LLEKGLKVK EFELKSYNFA DTGSFGFGID EHIDLGIKYD PSTGIYGMDF YVVLGRRGER VAHRKRKCSR VGHSHHVTKE E AMKWFEKV HDGIIFQAKK KKKMIRRRRR UniProtKB: Large ribosomal subunit protein uL5

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Macromolecule #13: Putative 60S ribosomal protein L9

Macromolecule	Name: Putative 60S ribosomal protein L9 / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 21.594295 KDa
Sequence	String: MVKVKSLCTL QIPEGVTVDV KGRKVTVTGK RGTLTKDLTH LQLDLRVDKK NRTFTVIRWF GSKIPIACLN TTKAHVQNMI TGVTKGYRF KVRCAYAHFP INVSVDGQNI EVRNFLGEKR VRRQLVPNTV KVSQTDPSKV KDEIVFDGND LEQVSREAAV L HQMCLVKK KDIRKFLDGI YVQTKTNIEG ME UniProtKB: Putative 60S ribosomal protein L9

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Macromolecule #14: Putative 60S ribosomal protein L6

Macromolecule	Name: Putative 60S ribosomal protein L6 / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 21.12674 KDa
Sequence	String: MAATKSAVSA AKRKAAKKVS RKSPEYTTLR KSCAPGAIAI ILAGRFRGRR AVILKQLPHN GPLVVSGPMK YNGVPIRRID SRYVIATST TVDISSVDTA PITAEVFQRP KAEKPTKSEG DFMGDKQKAK AEKAAKKTSK AGKKTLVSDA RAQLQKKIDA A LIAAIKKD ...String: MAATKSAVSA AKRKAAKKVS RKSPEYTTLR KSCAPGAIAI ILAGRFRGRR AVILKQLPHN GPLVVSGPMK YNGVPIRRID SRYVIATST TVDISSVDTA PITAEVFQRP KAEKPTKSEG DFMGDKQKAK AEKAAKKTSK AGKKTLVSDA RAQLQKKIDA A LIAAIKKD AQGKEKAGYL RSVFTVKPGD APHRWNW UniProtKB: Putative 60S ribosomal protein L6

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Macromolecule #15: 60S ribosomal protein L7a

Macromolecule	Name: 60S ribosomal protein L7a / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 29.824182 KDa
Sequence	String: MPGKEVKKVT QPAKAASPYK KPAVASHFAA RPKNFGIGQD VPYARDLSRF MRWPTFVTMQ RKKRVLQRRL KVPPALNQFT KVLDRASRN EALKLIKKYA PETRKARRER LQKVAEEKKK DPKKTVSTKA PLAVVTGLQE VTRAIEKKQA RMVVIANNVD P VELVLWMP ...String: MPGKEVKKVT QPAKAASPYK KPAVASHFAA RPKNFGIGQD VPYARDLSRF MRWPTFVTMQ RKKRVLQRRL KVPPALNQFT KVLDRASRN EALKLIKKYA PETRKARRER LQKVAEEKKK DPKKTVSTKA PLAVVTGLQE VTRAIEKKQA RMVVIANNVD P VELVLWMP NLCRANKIPY AIVKDMARLG DAIGRKTATC VALTDVNAED EATLKNLIRS VNARFLSRSD VIRRQWGGLQ LS LRSRAEL RKKHARNAGV DAAAIIQ UniProtKB: 60S ribosomal protein L7a

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Macromolecule #16: Putative 60S ribosomal protein L13a

Macromolecule	Name: Putative 60S ribosomal protein L13a / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 25.509248 KDa
Sequence	String: MAFPSRKDAF RAQRKGAKKH RPEIIVIDLK DHVLGRAAAV VAKQLLLGKK ITVVRCEQLN IAGTEIRNKI KYLQYLRKRK LTNPTKGPF HHRAPSDVFV RTVRSMLPRY TKRGMKALNS LVAYEGIPPN VVRTGGRVVI PRAQRHVCYR SERPYTVLGN M CKHVGWKY ...String: MAFPSRKDAF RAQRKGAKKH RPEIIVIDLK DHVLGRAAAV VAKQLLLGKK ITVVRCEQLN IAGTEIRNKI KYLQYLRKRK LTNPTKGPF HHRAPSDVFV RTVRSMLPRY TKRGMKALNS LVAYEGIPPN VVRTGGRVVI PRAQRHVCYR SERPYTVLGN M CKHVGWKY SDVVANLEKA RVEKASRHHE KQAKLRDAWK SARKEALAKM PKHNVEVLKK FGYA UniProtKB: Putative 60S ribosomal protein L13a

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Macromolecule #17: Putative 60S ribosomal protein L13

Macromolecule	Name: Putative 60S ribosomal protein L13 / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 24.848982 KDa
Sequence	String: MPKGNNAIPH VHQKKHWNPC SSQKGNVKVF LNQPAQKHRR RRLRLLKAKK VFPRPLKALR PQVNCPTVRH NMKRRLGRGF SPAELKAAG LNPQYAATIG IRVDSRRKNK SEEGMNVNVQ RLKTYMSKLV LFPMNHKKVQ KGEASEEEVK AATQDRSRFG D AAVGAVVY ...String: MPKGNNAIPH VHQKKHWNPC SSQKGNVKVF LNQPAQKHRR RRLRLLKAKK VFPRPLKALR PQVNCPTVRH NMKRRLGRGF SPAELKAAG LNPQYAATIG IRVDSRRKNK SEEGMNVNVQ RLKTYMSKLV LFPMNHKKVQ KGEASEEEVK AATQDRSRFG D AAVGAVVY PSAEAPRAVS AEEKSMCVYA FLKKNHSAVR FFGTRSSRAA RKEAAKEEKT GK UniProtKB: Putative 60S ribosomal protein L13

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Macromolecule #18: Putative 60S ribosomal protein L23

Macromolecule	Name: Putative 60S ribosomal protein L23 / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 14.982617 KDa
Sequence	String: MGKDQANVKG CRFRVSVALP VGAVVNCADN TGAKNLYVIS VKGYHGRLNR LPSAALGDMV MCSVKKGKPE LRKKVLNAVI IRQRKSWRR KDGTVIYFED NAGVIVNPKG EMKGSGIAGP VAKESADLWP KISTHAPAIV UniProtKB: Putative 60S ribosomal protein L23

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Macromolecule #19: Putative 40S ribosomal protein L14

Macromolecule	Name: Putative 40S ribosomal protein L14 / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 19.948615 KDa
Sequence	String: MVKSHYICAG RLVRILRGPR QDRVGVIVDI VDANRVLVEN PEDAKMWRHV QNLKNVEPLK YCVSVSRNCS AKALKDALAS SKALEKYAK TRTAARVEAK KACAVSTDFE RYQLRVARRS RAHWARKVFD EKDAKTPVSW HKVALKKMLK KAAKMDSTEG A KRRMQKAI AARKAKK UniProtKB: Putative 40S ribosomal protein L14

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Macromolecule #20: Putative 60S ribosomal protein L27A/L29

Macromolecule	Name: Putative 60S ribosomal protein L27A/L29 / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 16.135853 KDa
Sequence	String: MPTRFKKCRH QRGSTFCGYG RVGKHRKHES GRGNAGGMHH HRINFDKYHP GYFGKLGMDH YHRKKNPMWK PTINLNNLSR LIAAEEAAK AAKGGTLPVV DLQSSGYAKL LGNGHIQVPC IVKARYVSKL ADKKIRKAGG AVVLQA UniProtKB: Putative 60S ribosomal protein L27A/L29

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Macromolecule #21: Ribosomal protein L15

Macromolecule	Name: Ribosomal protein L15 / type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 24.497971 KDa
Sequence	String: MGAFMYLNEL WKKKSSDVMR FIQRIRSWEF RHQHTVVRLR RPTRPEKARM LGYKTKQGFC VFRVRVRRGG RKRPVHKGIT YGKPKTSGV LGMKLNKNNQ AVAEQRLGKR FGNLRVLNSY WVNMDSTFKW YEVIAVDPMC KTIRRDPRIN WIVNSVHKHR E QRGLTSAG ...String: MGAFMYLNEL WKKKSSDVMR FIQRIRSWEF RHQHTVVRLR RPTRPEKARM LGYKTKQGFC VFRVRVRRGG RKRPVHKGIT YGKPKTSGV LGMKLNKNNQ AVAEQRLGKR FGNLRVLNSY WVNMDSTFKW YEVIAVDPMC KTIRRDPRIN WIVNSVHKHR E QRGLTSAG RKHRGLRHKG HKASKLRPSY RAAWRRNNRI VFLRKR UniProtKB: Ribosomal protein L15

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Macromolecule #22: Putative 60S ribosomal protein L10

Macromolecule	Name: Putative 60S ribosomal protein L10 / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 24.607186 KDa
Sequence	String: MARRPSRCYR FCKNKPYPKS RFCRGVPDPK IRNFDIGRRR ATVDEFPVCI HVVSRELEQI ASEALEAARI QANKYMVKRA NKDVFHMRT RAHPFHVLRI NKMLSCAGAD RLQTGMRGAF GKPNGVCARV RIGQILLSMR TKEAYVPQAF EALRRAKMKF P GRQIIVMS ...String: MARRPSRCYR FCKNKPYPKS RFCRGVPDPK IRNFDIGRRR ATVDEFPVCI HVVSRELEQI ASEALEAARI QANKYMVKRA NKDVFHMRT RAHPFHVLRI NKMLSCAGAD RLQTGMRGAF GKPNGVCARV RIGQILLSMR TKEAYVPQAF EALRRAKMKF P GRQIIVMS KYWGFTNILR TEYEALRDAG KLEQRGTHCK LIAPKGKITM RNVMA UniProtKB: Putative 60S ribosomal protein L10

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Macromolecule #23: Putative 60S ribosomal protein L5

Macromolecule	Name: Putative 60S ribosomal protein L5 / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 34.058594 KDa
Sequence	String: MPFVKVVKNK AYFKRFQVKY RRRREGKTDY HARRQMVLQD KTKFGSPKYR LVVRITNKDI IAQIVQAKIV GDEVVMAAYA HELPAFGIE HGLTNYAAAY ATGLLLARRT LAKLGIADKF QGAKEADGSY SAVRTKKDDE GDDEERFPFK AILDVGLART T TGARVFGV ...String: MPFVKVVKNK AYFKRFQVKY RRRREGKTDY HARRQMVLQD KTKFGSPKYR LVVRITNKDI IAQIVQAKIV GDEVVMAAYA HELPAFGIE HGLTNYAAAY ATGLLLARRT LAKLGIADKF QGAKEADGSY SAVRTKKDDE GDDEERFPFK AILDVGLART T TGARVFGV LKGAVDGGMA VPHRPNRFPG YNKEKSSLDA KVHRDRIFGK HVADYLKQVK EEASSNPDEK CVQFSKYMAA KV LPESIEG MYKKAHAAIR ADPSKSLPKK AKKEGVAHKS YKTKKLSGAE KRAAAKAKVA AIRERLGK UniProtKB: Putative 60S ribosomal protein L5

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Macromolecule #24: 60S ribosomal protein L18

Macromolecule	Name: 60S ribosomal protein L18 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 22.07108 KDa
Sequence	String: MGVDLTGISK KSRVIRHHTY STNPYIKLLI KLYKFLAKRT SSGFNKVVYQ RLIKSRSNRA PISLSRIAVV MKRKAVFTAK SKAAPIAVV VGDVLDDVRM ARIPAMRVCA LRFSKSARQS IVAAGGECLT FDQLAMIAPT GKNTYLLRGR KSGRESVRHF G ASGVPGSH ...String: MGVDLTGISK KSRVIRHHTY STNPYIKLLI KLYKFLAKRT SSGFNKVVYQ RLIKSRSNRA PISLSRIAVV MKRKAVFTAK SKAAPIAVV VGDVLDDVRM ARIPAMRVCA LRFSKSARQS IVAAGGECLT FDQLAMIAPT GKNTYLLRGR KSGRESVRHF G ASGVPGSH SKPYATNRGK ETKRGRRTGR SYKRKAFRHV UniProtKB: Large ribosomal subunit protein eL18

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Macromolecule #25: Putative 60S ribosomal protein L19

Macromolecule	Name: Putative 60S ribosomal protein L19 / type: protein_or_peptide / ID: 25 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 28.896115 KDa
Sequence	String: MVSLKLQARL ASSILGCGRA RVWLDPNEAV EIQNANSRKS VRKLIKDGFI IRKPVKVHSR ARWRKMKEAK DMGRHNGVGR REGSREARM PSKELWMRRL RILRRLLRKY RADKKIDRHV YRDLYMRAKG NVFRNKRNLV EHIHKIKNEK KKERQLAEQL A AKHLRDEQ ...String: MVSLKLQARL ASSILGCGRA RVWLDPNEAV EIQNANSRKS VRKLIKDGFI IRKPVKVHSR ARWRKMKEAK DMGRHNGVGR REGSREARM PSKELWMRRL RILRRLLRKY RADKKIDRHV YRDLYMRAKG NVFRNKRNLV EHIHKIKNEK KKERQLAEQL A AKHLRDEQ NRNKARKQEL KKREKERERA RRDDAAAAAQ KKKADAAKKS AAPAAKSAAP AAKAAAPATK AAAPATKAAA AA PATKGAA PVKKSKK UniProtKB: Putative 60S ribosomal protein L19

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Macromolecule #26: 60S ribosomal protein L18a

Macromolecule	Name: 60S ribosomal protein L18a / type: protein_or_peptide / ID: 26 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 20.852338 KDa
Sequence	String: MVKPHLRHYQ VVGRESPSEK NPEPTVYKFE VFAPNFVVAK SRFWRMMRVK NKVKATHGDV LSCKVVKDAK LVARNYLVDI AYYSQRCGY TRMVKEFRDV SKTGAVSQAY HDLASRHRAR YHNIEVLNVK SIPDHEVKHL SIAQYHAPNL SFPLLQRRTK A TRKDRAIF VKKNTKRAVV A UniProtKB: 60S ribosomal protein L18a

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Macromolecule #27: Putative 60S ribosomal protein L21

Macromolecule	Name: Putative 60S ribosomal protein L21 / type: protein_or_peptide / ID: 27 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 18.068223 KDa
Sequence	String: MVHSYGYKSG TRHLFAKKFR KHGVPSVSTI LTNIKVGDYV DVVADSAVRE GMPHKYYHGR TGIVWNVTPR GVGVIINKPV RTRTLRKRI CVRFEHVRKS RCQEAFKAKE HQFQAYLAAK KAGKALPPLQ KSSRLGGIVR PKNVEVLARR VADYEAMVPY UniProtKB: Putative 60S ribosomal protein L21

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Macromolecule #30: 40S ribosomal protein S3a

Macromolecule	Name: 40S ribosomal protein S3a / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 30.062037 KDa
Sequence	String: MALGKNKRIS KGGKRGKRGK AQETMARKEW YDVVAPANFE KRQFAKTICN KTQGTRIAAD VLRGRVFEAN LADLNQSAGE EEAYRKVRF TVQEVQGRNL LTQFHSMEVT TDKMASLLRK WCTTMETTVE VKTADGYTMR LFVVAFTKPQ ANQQSRNCYA K QRLVKWLR ...String: MALGKNKRIS KGGKRGKRGK AQETMARKEW YDVVAPANFE KRQFAKTICN KTQGTRIAAD VLRGRVFEAN LADLNQSAGE EEAYRKVRF TVQEVQGRNL LTQFHSMEVT TDKMASLLRK WCTTMETTVE VKTADGYTMR LFVVAFTKPQ ANQQSRNCYA K QRLVKWLR MRITKMIKRR LSKVQIKEAV SLLTRNVLSD ALVRRCNPIL PLRELRIRKV RVVRTPKFDA QALLSAHGTI PA SVEADQR EVEEAVEAAP AAEKAAE UniProtKB: Small ribosomal subunit protein eS1

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Macromolecule #31: 40S ribosomal protein SA

Macromolecule	Name: 40S ribosomal protein SA / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 27.536629 KDa
Sequence	String: MSAVESGSKV LRMKESDAQK LLAMRCHIGT RNQSSAMKKY IYGRTAEGSH IIDVHMMWEK LILAARVIAA VENPKDVCVC SSRLYGTRA IYKFSQHVGT SFHGGRFIPG TFTNQIQKKF VQPRVLVVTD PRTDHQAIRE ASLVNIPVIA LCDTDAPLEY V DIAIPCNN ...String: MSAVESGSKV LRMKESDAQK LLAMRCHIGT RNQSSAMKKY IYGRTAEGSH IIDVHMMWEK LILAARVIAA VENPKDVCVC SSRLYGTRA IYKFSQHVGT SFHGGRFIPG TFTNQIQKKF VQPRVLVVTD PRTDHQAIRE ASLVNIPVIA LCDTDAPLEY V DIAIPCNN RGIKSIGMMY WLLAREVLRL RGTIVRSVPW EEKVDLFFYR DPNEAAEEKA AAAAAAPAAE AEEGFGWVER ND DNAWEA UniProtKB: Small ribosomal subunit protein uS2

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Macromolecule #32: Putative 40S ribosomal protein S3

Macromolecule	Name: Putative 40S ribosomal protein S3 / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 24.511762 KDa
Sequence	String: MGPLSKKRMI IRDGVFYAEL FEFLKRELAE EGFSGVSYHV TTLRTEIVIK ATKTREVLGV NGRRIRELTA CIQQRFNYKE GKLQLYVER VEVRGLSAMA QVESLRFKLL SNLQVRRAAM GIIRYVMESG AKGCEVTVGG KIKGQRAKSM TFRDGYMIKS G TAHKSFVD ...String: MGPLSKKRMI IRDGVFYAEL FEFLKRELAE EGFSGVSYHV TTLRTEIVIK ATKTREVLGV NGRRIRELTA CIQQRFNYKE GKLQLYVER VEVRGLSAMA QVESLRFKLL SNLQVRRAAM GIIRYVMESG AKGCEVTVGG KIKGQRAKSM TFRDGYMIKS G TAHKSFVD SACRHCYMRA GCIGVKVKIM LPGDSTGRNG PSEPLPDVIT VIEPKQITAS E UniProtKB: 40S ribosomal protein S3

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Macromolecule #33: Putative 40S ribosomal protein S9

Macromolecule	Name: Putative 40S ribosomal protein S9 / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 22.188902 KDa
Sequence	String: MRNYNNFNRV WKAPRRPFEK ERLDREMKLC GQYGLRCKRE IWRVNMTLSK MRRTARLLLT LPENHPRRLL EGSAIMRRCH EYGFLDEEK DKLDYVLSLT VPDILERRLQ TIVFKAGLAK SVHHARVLIQ QRHIAVAKQI VTIPSFIVRV SSERHIAFAD A SPFGNGRT GRVKRVRAKA AKRHAGGGDD DE UniProtKB: Putative 40S ribosomal protein S9

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Macromolecule #34: 40S ribosomal protein S4

Macromolecule	Name: 40S ribosomal protein S4 / type: protein_or_peptide / ID: 34 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 30.742084 KDa
Sequence	String: MAKKHLKRLY APKDWMLSKL TGVFAPRPRP GPHKLRECLP LLVIIRNRLK YALNAREGEM ILRQGLVHVD NHPRRDGKYP AGFMDVVEI PKTGDRFRLM YDVKGRFALV NLSEAEAQIK LMKVVNLYTA TGRVPVAVTH DGHRIRYPDP HTSIGDTIVY N VKEKKCVD ...String: MAKKHLKRLY APKDWMLSKL TGVFAPRPRP GPHKLRECLP LLVIIRNRLK YALNAREGEM ILRQGLVHVD NHPRRDGKYP AGFMDVVEI PKTGDRFRLM YDVKGRFALV NLSEAEAQIK LMKVVNLYTA TGRVPVAVTH DGHRIRYPDP HTSIGDTIVY N VKEKKCVD LIKNRQGKAV IVTGGANRGR IGEIVKVECH PGAFNIAHLK DASGAEFATR AANIFVIGKD LNNLQVTVPK QQ GLRMNVI QEREERLIAA EARKNAPARG ARRARK UniProtKB: 40S ribosomal protein S4

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Macromolecule #35: 40S ribosomal protein S2

Macromolecule	Name: 40S ribosomal protein S2 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 28.791135 KDa
Sequence	String: MADTQPAQEA PATDAPRAER NFGRGRGGRG GRGRGRGGPG EEKEWVPCTK LGRLVKAQKV TSLEEIFLFS MPIKEHQIVD TLIAEGQLH DEMMKIYPVQ KATSAGQRTR FKAFNVVGDC DGHIGIGARV GKEVSLAIRA SMIAAKLNIV PVRRGYWGNK I GEPHTIPM ...String: MADTQPAQEA PATDAPRAER NFGRGRGGRG GRGRGRGGPG EEKEWVPCTK LGRLVKAQKV TSLEEIFLFS MPIKEHQIVD TLIAEGQLH DEMMKIYPVQ KATSAGQRTR FKAFNVVGDC DGHIGIGARV GKEVSLAIRA SMIAAKLNIV PVRRGYWGNK I GEPHTIPM KVTGKCGSVA VRLVPAPRGT GIVAAPVPKK ILEFAGVEDV YTSSRGKTRT HGNLIMATFY ALRKTYGFLT PD LWADTEP SRDPTDEHAE LLAEMTTA UniProtKB: Small ribosomal subunit protein uS5

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Macromolecule #36: 40S ribosomal protein S6

Macromolecule	Name: 40S ribosomal protein S6 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 28.370227 KDa
Sequence	String: MKLNIAYPRN GTVKQFEISD EVLRRVQLQD YRLGNEVDGA IFGSEFKGYI FRLRGGSDKD GFPMVPGVLA SSRVSLLVKR GAIGFNTFR GYQGERRRKN VRGCVLASDI ALVNVTISKV GDQPIEGVTD TTAPRRLGPK RASKIRKLFN LSRTEDVRKY V VRRRVVKS ...String: MKLNIAYPRN GTVKQFEISD EVLRRVQLQD YRLGNEVDGA IFGSEFKGYI FRLRGGSDKD GFPMVPGVLA SSRVSLLVKR GAIGFNTFR GYQGERRRKN VRGCVLASDI ALVNVTISKV GDQPIEGVTD TTAPRRLGPK RASKIRKLFN LSRTEDVRKY V VRRRVVKS GKKDRLKAPK IQRLITPRVK ARRAKKAKDA IAKVRASAAE RREYLRLIAS NRRALRQRDH SKKHTRKVHA QR AEVAAFQ KK UniProtKB: Small ribosomal subunit protein eS6

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Macromolecule #37: 40S ribosomal protein S5

Macromolecule	Name: 40S ribosomal protein S5 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 21.336623 KDa
Sequence	String: MSSKTPKLFN KWSFEGLETS ELALRDHIST TAAYVPHTSG RWQKRRFYKA RMPIVERLAN GLMFKGRGNG RKLQAARLLK HTLEIIHLL TDENPLQVVV DAVSKGAPRE DSTRVGSGGV VRRQAVDVSP MRRVNEAIYQ MCKGAREAAF RNLKSMPECL A DEIVNASK GSSNSYAIKK KDEVERVAKA NR UniProtKB: 40S ribosomal protein S5

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Macromolecule #38: 40S ribosomal protein S7

Macromolecule	Name: 40S ribosomal protein S7 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 23.765207 KDa
Sequence	String: MQPHLRKLRK LKRGKPSDLE ESVAKALFEL EASHKTLRQE LPRFHVNTVR EVKVPRSKKT VLVVFYPLRF LMLVRKVQRA LTSELEKRH PGCLVMLVAQ RQITKRPTDV YKLQKVQRSK TSTAVFENIL NDMIYPSDVV GRRWRCRTDG SKLMKVFLDA R DRKRIESR ...String: MQPHLRKLRK LKRGKPSDLE ESVAKALFEL EASHKTLRQE LPRFHVNTVR EVKVPRSKKT VLVVFYPLRF LMLVRKVQRA LTSELEKRH PGCLVMLVAQ RQITKRPTDV YKLQKVQRSK TSTAVFENIL NDMIYPSDVV GRRWRCRTDG SKLMKVFLDA R DRKRIESR LRAVAYVYKQ LTHRRVSFGF MWNPKLQQVS TR UniProtKB: 40S ribosomal protein S7

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Macromolecule #39: Putative 40S ribosomal protein S15A

Macromolecule	Name: Putative 40S ribosomal protein S15A / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 14.719258 KDa
Sequence	String: MTMMSVLANA LRTIASAERR GKRQVLIRPS SKVVVKFLQV MQKHGYIGEF EIIDDHRAGK IVVNLNGRLN KCGAICPRFD CATTDYEKW MKNILPSRQF GFVVLTTSLG IMDHEEARSR NTGGKVLGFF Y UniProtKB: Putative 40S ribosomal protein S15A

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Macromolecule #40: 40S ribosomal protein S8

Macromolecule	Name: 40S ribosomal protein S8 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 24.98425 KDa
Sequence	String: MGIVRSRLHK RKITGGKTKI HRKRMKAELG RLPANTRLGA RRVSPVRARG GNFKIRALRL DTGNFAWASE AIAHRVRLLD VVYNATSNE LVRTKTLVKN CIVAVDAAPF KRWYAKHYGI DLDADKKSTK AAVAAEKKGR KSAHAAADKY DVNKASPKLQ R EWTRRRRN ...String: MGIVRSRLHK RKITGGKTKI HRKRMKAELG RLPANTRLGA RRVSPVRARG GNFKIRALRL DTGNFAWASE AIAHRVRLLD VVYNATSNE LVRTKTLVKN CIVAVDAAPF KRWYAKHYGI DLDADKKSTK AAVAAEKKGR KSAHAAADKY DVNKASPKLQ R EWTRRRRN HRVEKAIADQ LREGRVLARI TSRPGQSGRA DGILLEGAEL QFYLKRLEKK KK UniProtKB: Small ribosomal subunit protein eS8

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Macromolecule #41: Putative 40S ribosomal protein S16

Macromolecule	Name: Putative 40S ribosomal protein S16 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 16.718586 KDa
Sequence	String: MPADKSYALK QVQTFGKKKT AIAVATVTKA AQCNIKVNGV PLQQILPDTL RAKIMEAITV VGSKYYSRLR IDVAVHGGGQ VSQAYAARQ AIAKGLIAFF QKYHNEVEKA ALKDKFLAYD KFLLIADPRR CEPKKWGRHS ARTRFTKSYR UniProtKB: Ribosomal protein S16

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Macromolecule #42: Putative ribosomal protein S20

Macromolecule	Name: Putative ribosomal protein S20 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 13.031983 KDa
Sequence	String: MDYPKKNQAA PAEGQTVRLT ITSRNAKAVE SVTSQLLTRA RDEKVTIHGP VRLPTRTLKI TTRKTPCGNG TNTWDTFELK IYKRIIDLH APTEQVKKIT SFTMESGVDV SITILDR UniProtKB: Putative ribosomal protein S20

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Macromolecule #43: Putative 40S ribosomal protein S10

Macromolecule	Name: Putative 40S ribosomal protein S10 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 18.681125 KDa
Sequence	String: MSTYVPKPSR DNVYRFFFTE GVIACKKDRM GTWTGTLGGN TFTVPCIQVM QLMRSLKSRN LIKEQYAWRH YYWTLNDEGI AYMRSYLHL APSAMPNTQK PSSVNFEKVT EGRGRGRGRG GRGRGEGRGR GRGEGRGRGR GRGFGGERMN YRAAAATSDG E AAPAPAAE UniProtKB: Putative 40S ribosomal protein S10

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Macromolecule #44: 40S ribosomal protein S14

Macromolecule	Name: 40S ribosomal protein S14 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 15.62318 KDa
Sequence	String: MSKKQEVKAY GPNVKKGDLV YGVVHIFASF NDTFVHVTDM SGRETYVKVT GGMKVKADRD ESSPYAAMMA AQDVVARCKE CGINALHVK MRAVGGVRTK SPGPGAQAAL RALARAGMKI GRIEDVTPIP TDSTRRKGSR RGRRL UniProtKB: 40S ribosomal protein S14

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Macromolecule #45: Putative 40S ribosomal protein S23

Macromolecule	Name: Putative 40S ribosomal protein S23 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 15.969643 KDa
Sequence	String: MTKTNGQNAA RKLVRLRCRN RWADKGWKRA HTFSARKANP FGGSSHAKGI VLEKIGVGAK QPNSAIRKCV RVQLIKNDKK IIAFVPNDG CLHFIEENDE VLVSGFGRSG HAVGDIPGVR FKIVKVSNVG LYALYRQKKE KPRN UniProtKB: Putative 40S ribosomal protein S23

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Macromolecule #46: 40S ribosomal protein S12

Macromolecule	Name: 40S ribosomal protein S12 / type: protein_or_peptide / ID: 46 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 15.627837 KDa
Sequence	String: MAEETVRVEV PAVEENVVVD VAPESLEDAV RIVIQKSLEA NGLVRGLSEV ARTLDCKTAH MCILADDCED EEYKKLVTAL AKQGNIDLI NVEEREKLAQ WAGLVRRDVA GEVTKTLKCS SVAIRDFGER TKALDYLLSQ LH UniProtKB: 40S ribosomal protein S12

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Macromolecule #47: Putative 40S ribosomal protein S18

Macromolecule	Name: Putative 40S ribosomal protein S18 / type: protein_or_peptide / ID: 47 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 17.433422 KDa
Sequence	String: MSLTLIPDHF QHIVRLLNTN VEGKRKVPFA LRMVKGVGIR FAYLVCKKAG IDVERRAGTL TAEELEKIAE IIADPAKFKI PDWFLNRQR DPKTGKTEHL SSSMVDTRLR DDLERLKKMR AHRGVRHAYG LRVRGQHTCT SGRHGKTVGV SRGK UniProtKB: Ribosomal protein S18

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Macromolecule #48: Putative ribosomal protein S29

Macromolecule	Name: Putative ribosomal protein S29 / type: protein_or_peptide / ID: 48 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 6.696929 KDa
Sequence	String: MGHLDQWRSR QKIGMGKGAR CCVICSNQKA LIRKYELNVC RQCFRENAEH IGFTKLR UniProtKB: Putative ribosomal protein S29

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Macromolecule #49: Putative 40S ribosomal protein S13

Macromolecule	Name: Putative 40S ribosomal protein S13 / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 17.482764 KDa
Sequence	String: MVRMHGNGRG KASSALPYRR TPPAWLKIAS RNVVKMVCKS SRKGMMPSQI GMELRDSMGI AQVKNVTGRK ILRILKHNGL APEIPEDLY FLVKRATQMR KHLERHTTDR DTKYRLILVE SRIHRLARYY KRVKQLPPTW KYESSTASAM VA UniProtKB: Putative 40S ribosomal protein S13

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Macromolecule #50: Putative 40S ribosomal protein S11

Macromolecule	Name: Putative 40S ribosomal protein S11 / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 20.023457 KDa
Sequence	String: MPVAPQYYHA HAVDATIQHE KAYQRQTAVN ENMHRPSRKH VNKSGHIRYS KKIGLGFKTP AKALNGKYID RKCPFTSNVV IRGRILRGV VHSTKMHRTI IIRRNYLHFI KKYQRYQKRH KSLAVHCSPA FDPKQGDEVV IGQCRPLSKT IRYNVLEVVS K SSADKMGK KFAKN

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Macromolecule #51: Putative 40S ribosomal protein S17

Macromolecule	Name: Putative 40S ribosomal protein S17 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 16.551529 KDa
Sequence	String: MGKIRTKTVK RASRQVVEKY YSKLNFDFYQ NKRVIMDVTI AESKKLKNKI AGYTTHIMKR LARGPVRGIS LKLQEEERER RMDHAPATS DVDKVIQSGV SVDKKTMQML QRLEIGVPRR VKRADAAVTK VKAAPRRRQQ KSSK UniProtKB: Putative 40S ribosomal protein S17

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Macromolecule #52: Putative 40S ribosomal protein S15

Macromolecule	Name: Putative 40S ribosomal protein S15 / type: protein_or_peptide / ID: 52 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 17.472395 KDa
Sequence	String: MASNITAERY EQLKKERTFH KFTYRGLEID PLLALSEEEF KALVHARARR NMNRHADRRP PVLLKRLREA KKHVKVGEKP KAVKTHLRD VVITPEMVGS VVAIYNGHQF NAVEIKGEMI GHYLGEFSMS YRPVLHGRPG VGATHSSRFI PIK UniProtKB: Putative 40S ribosomal protein S15

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Macromolecule #53: 40S ribosomal protein S19-like protein

Macromolecule	Name: 40S ribosomal protein S19-like protein / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 18.158078 KDa
Sequence	String: MTAPRNKIHR IGKRKGATLK DVSAWRWIKT AARHFKQEGK IFVPNCTEIM KSSHGRERAP QNPDWYYIRC AAVLRAIYLR PGVGYGGLS KRFGNKKNYG SRPEHTVTSS TGPLHWACKS LTKLGLVEPG AQSGQRLTRK GHKFADSLAF QVQIRKFGQS K A UniProtKB: 40S ribosomal protein S19-like protein

+
Macromolecule #54: Putative 40S ribosomal protein S21

Macromolecule	Name: Putative 40S ribosomal protein S21 / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 17.035592 KDa
Sequence	String: MATIGMFNEE GENVDLYIPR KCHATTTLIE AHDHAAVQIS IANVGPNGVI NGTTTTLCIA GYLRSQGESD HAINHITIDR GIMRIKTGK PKRASKSKSK KPAAKGAAAG AAAQKGARPP AQKGARPPAQ KGARPPAQKG ARPPAQKGAR PPAQKGAAPA R KNRA UniProtKB: Putative 40S ribosomal protein S21

+
Macromolecule #55: 40S ribosomal protein S24

Macromolecule	Name: 40S ribosomal protein S24 / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 15.808882 KDa
Sequence	String: MVFQKKKAEV CIRTSQFKVN KLLNRKQFIV EVNHPHWCGT VPTQLIRKKL ATLYKVPDAS QVSLFGFKTK FGGGKTTGFG LIYDDLASL KRFEPNYRKT RMGFGKARLP ARKSVKERRN RNKKLRGKAK GKQVAKKK UniProtKB: 40S ribosomal protein S24

+
Macromolecule #56: 40S ribosomal protein S25

Macromolecule	Name: 40S ribosomal protein S25 / type: protein_or_peptide / ID: 56 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 13.071399 KDa
Sequence	String: MPPKAGQTKK AKMEAANKGA KKTTKKWSKG QSREALQNAV MFDKETYDKL RSEVPKYKLI TPSIISDRLK IAVSIAAAGL KQLCREKLI RLVSCSSKTR VYTRIVQAAP AEAAAAAPAA E UniProtKB: 40S ribosomal protein S25

+
Macromolecule #57: 40S ribosomal protein S26

Macromolecule	Name: 40S ribosomal protein S26 / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 12.794251 KDa
Sequence	String: MTTKRRNHGR SKPAHSRGRV KPIHCFNCGR LTPKDKAVGR FVVRRMLDAA SARDVAEASP VYGANFPMPR LYMKQRFCIA CAIHSRTVR ARPVGNRKIR YTKKVPFRPA GKK UniProtKB: 40S ribosomal protein S26

+
Macromolecule #58: Putative 40S ribosomal protein S27-1

Macromolecule	Name: Putative 40S ribosomal protein S27-1 / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 9.819463 KDa
Sequence	String: MGFFDADLSY PTVRTERMKH KRRRLVQGPN SYFMDVSCPR CRQVTVVYSH ATTSVECKGC SKKLCRPTGG KALLVEGCGY RRKPDH UniProtKB: Putative 40S ribosomal protein S27-1

+
Macromolecule #59: Putative 40S ribosomal protein S33

Macromolecule	Name: Putative 40S ribosomal protein S33 / type: protein_or_peptide / ID: 59 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 9.763191 KDa
Sequence	String: MADSKKDNKK TEEVVTQGTD QAQVGLIIKV LGRTGSRGNV TQVRVRLMAE AGSPDYNRTI VRNVKGPCKE NDMLSLMETE REARRLR UniProtKB: Putative 40S ribosomal protein S33

+
Macromolecule #60: 40S ribosomal protein S30

Macromolecule	Name: 40S ribosomal protein S30 / type: protein_or_peptide / ID: 60 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 7.394894 KDa
Sequence	String: MGKIHGSLAR AGKVKNQTPK VAKQEKPKQP RGRALKRLKY TRRFLSKTVK PGEKVHMNKQ PPGKAG UniProtKB: 40S ribosomal protein S30

+
Macromolecule #61: Ubiquitin-60S ribosomal protein L40

Macromolecule	Name: Ubiquitin-60S ribosomal protein L40 / type: protein_or_peptide / ID: 61 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 17.062781 KDa
Sequence	String: MQIFIKDAAG RSVAVRVSAE DTVGFLKAQA NVTQGNLFFA GMCLAEEETL AAYGLSKEST VDVVIPVEGG KGKKKKKRIF TKPKKPTHR HKLEKMRALK YFKVTENDDG SYKVERTRQD CPHPQCGAGV YMAQHKDRQY CGKCHLTYKA ESK UniProtKB: Ubiquitin-ribosomal protein eL40 fusion protein

+
Macromolecule #62: Guanine nucleotide-binding protein subunit beta-like protein

Macromolecule	Name: Guanine nucleotide-binding protein subunit beta-like protein type: protein_or_peptide / ID: 62 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 34.441516 KDa
Sequence	String: MNYEGHLKGH RGWVTSLACP QQAGSYIKVV STSRDGTAIS WKANPDRHSV DSDYGLPNHR LEGHTGFVSC VSLAHATDYA LTASWDRSI RMWDLRNGQC QRKFLKHTKD VLAVAFSPDD RLIVSAGRDN VIRVWNVAGE CMHEFLRDGH EDWVSSICFS P SLEHPIVV ...String: MNYEGHLKGH RGWVTSLACP QQAGSYIKVV STSRDGTAIS WKANPDRHSV DSDYGLPNHR LEGHTGFVSC VSLAHATDYA LTASWDRSI RMWDLRNGQC QRKFLKHTKD VLAVAFSPDD RLIVSAGRDN VIRVWNVAGE CMHEFLRDGH EDWVSSICFS P SLEHPIVV SGSWDNTIKV WNVNGGKCER TLKGHSNYVS TVTVSPDGSL CASGGKDGAA LLWDLSTGEQ LFKINVESPI NQ IAFSPNR FWMCVATERS LSVYDLESKA VIAELTPDGA KPSECISIAW SADGNTLYSG HKDNLIRVWS ISDAE UniProtKB: Activated protein kinase c receptor

+
Macromolecule #63: Putative RNA binding protein

Macromolecule	Name: Putative RNA binding protein / type: protein_or_peptide / ID: 63 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 25.229275 KDa
Sequence	String: MPAKAAAKPV KPAAKAAPKP ANKAPAPKAA AAKPVAKAAP KAAAPAARPA SGSSNGVYVK NWGTGSVADA ANVFSAAGKV VKVQLRRQR YAIVFFENSA AVKKAIDLFN EKEVLGKTVL VVPAKTSPKP DAHENSSCVF VSPIFRPSTT KAQVMELFAG V KVQRLRMY ...String: MPAKAAAKPV KPAAKAAPKP ANKAPAPKAA AAKPVAKAAP KAAAPAARPA SGSSNGVYVK NWGTGSVADA ANVFSAAGKV VKVQLRRQR YAIVFFENSA AVKKAIDLFN EKEVLGKTVL VVPAKTSPKP DAHENSSCVF VSPIFRPSTT KAQVMELFAG V KVQRLRMY RQNFAYAYLD SPAAAKKFVE EKNGTEFRGH TLRVALSARS LEKLRARQEA ANVVIAAHRH YKTHERQ UniProtKB: Putative RNA binding protein

+
Macromolecule #64: Putative 60S ribosomal protein L17

Macromolecule	Name: Putative 60S ribosomal protein L17 / type: protein_or_peptide / ID: 64 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 19.124547 KDa
Sequence	String: MTHYSRKPQV SSKSAKAKVS DLRCHYKNTF ETANVINGMP LRKAQQLYRQ VLAKTRCIPF KRYNGKIGRT AQAKEWGQTK GRWPRKSVV AMMSLLKNAE ANAIEKGLDP NQMVIKHVQV DQAARMRRRT YRAHGRITPY MCSPCHVQLF MSEKKERVPA P KSAPKK UniProtKB: Putative 60S ribosomal protein L17

+
Macromolecule #65: Putative 60S ribosomal protein L22

Macromolecule	Name: Putative 60S ribosomal protein L22 / type: protein_or_peptide / ID: 65 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 15.030535 KDa
Sequence	String: MVAVRAKVGS RSYVRQKQLA KGKKVFKIDC SIPAADGIFS EDVLGNFEQF FQDNTKLNGR KGKLSDKVRL SMNDNVLTIS TTMAYRKKY FKYLTKKFLK KKDLRDWIRI LATGKGTYQL KYFNIQDQEE UniProtKB: Large ribosomal subunit protein eL22

+
Macromolecule #66: Putative 60S ribosomal protein L23a

Macromolecule	Name: Putative 60S ribosomal protein L23a / type: protein_or_peptide / ID: 66 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 16.372358 KDa
Sequence	String: MPPAQKTAKK AAPKDAKATK VVKVTTRKSY TRPQFRRPHT YRKPAMAKPS NRVTVESKDI AAFNVIRYPL TTDKAMKKIE ENNTLTFIV DSRANKTEIK KAMRKLYQVK AVKVNTLIRP DGLKKAYIRL SAAHDALDTA NKIGLV UniProtKB: Putative 60S ribosomal protein L23a

+
Macromolecule #67: Putative 60S ribosomal protein L26

Macromolecule	Name: Putative 60S ribosomal protein L26 / type: protein_or_peptide / ID: 67 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 16.21715 KDa
Sequence	String: MASIKCGSRR KARRAHFQAP SHVRRVLMSA PLSKELRAKY NVRAMPVRKD DEVIVKRGTF KGREGKVTAC YRLKWVILID KVNREKANG STVAVGIHPS NVEITKLKLT HHRKSILERK DRSSKSDKGK GKISAADKAM QQMD UniProtKB: Putative 60S ribosomal protein L26

+
Macromolecule #68: Putative ribosomal protein L24

Macromolecule	Name: Putative ribosomal protein L24 / type: protein_or_peptide / ID: 68 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 14.608168 KDa
Sequence	String: MRTIECEFSH FAVHPGHGRR YVPFAFLSTK PVLTFSRPKC FALYMRKKNP RFIPWTRTYR RIHRKTTTDR VNRRRAARAV RVQRAIVGA DLSYIQEVRA ARKEDRSAKA KAVRAEVAER KAAKK UniProtKB: Putative ribosomal protein L24

+
Macromolecule #69: 60S ribosomal protein L27

Macromolecule	Name: 60S ribosomal protein L27 / type: protein_or_peptide / ID: 69 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 15.46933 KDa
Sequence	String: MTKFLKPGKV VIVTAGRYAG HKAVIVQNSD VVTKERPYGR ALLAGIKKYP KKVVRGMSKQ TIARRSQVGV FLRVVNHKHF LPTRYNVDM SKELRGKINV SDASKRSRSK RLVRHVFQAR YNAGSSMWFF QRLRF UniProtKB: Putative ribosomal protein L27

+
Macromolecule #70: Putative 60S ribosomal protein L28

Macromolecule	Name: Putative 60S ribosomal protein L28 / type: protein_or_peptide / ID: 70 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 16.314906 KDa
Sequence	String: MSHSVDLQWV LVRQNSRFLQ KRGGIRMSND PFNNNGNWTK RHCGFLNEKA AVVKPAKGGA ICVTVKDGSS NNKPRQTYKK TVHAAGVRA SDVSRAVAAV RPDLADVSFR RARRMACIAS RTAKVAAARK ARSEKIKFSR KSARAKRN UniProtKB: Putative 60S ribosomal protein L28

+
Macromolecule #71: Putative 60S ribosomal protein L35

Macromolecule	Name: Putative 60S ribosomal protein L35 / type: protein_or_peptide / ID: 71 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 15.262208 KDa
Sequence	String: MSHHMKIKDL REKSKDDLLK TLTEYKKELS QLRVVQQTGG AETRLGRIRP IRKSIARILT VLNQNERSNL KMFYADRKLR CKTPKVLRT KLTHRRRLAL KENEKNRKTS RQMRQAHKFP KRVYAVKI UniProtKB: Putative 60S ribosomal protein L35

+
Macromolecule #72: 60S ribosomal protein L29

Macromolecule	Name: 60S ribosomal protein L29 / type: protein_or_peptide / ID: 72 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 8.001308 KDa
Sequence	String: MAKSKNHTNH NQSSKNHRNG IKGPVPLHLH NSKRGSWLPA LVNARRVRKH NQKAALKKRR ERIAAFAAKN UniProtKB: 60S ribosomal protein L29

+
Macromolecule #73: Putative 60S ribosomal protein L7

Macromolecule	Name: Putative 60S ribosomal protein L7 / type: protein_or_peptide / ID: 73 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 28.900037 KDa
Sequence	String: MATHSVYGNA SDMPAVPAPE SAIKRAAFKQ QQTESFKKAV VARKAAKAAL KKTAYLRARK YSREYRGAEK KLVTLRRQAA SHGNYYLEA KPKVAVVTRI RGIAKVNPKQ RKILQLLRLR QIFNTVFVKM NKPMENMLRA VEPYIAYGYP SLATVRAMVY K RGYLKING ...String: MATHSVYGNA SDMPAVPAPE SAIKRAAFKQ QQTESFKKAV VARKAAKAAL KKTAYLRARK YSREYRGAEK KLVTLRRQAA SHGNYYLEA KPKVAVVTRI RGIAKVNPKQ RKILQLLRLR QIFNTVFVKM NKPMENMLRA VEPYIAYGYP SLATVRAMVY K RGYLKING QRVKITDNQM IKDKYNNVDI VCAEDMVNQI YTCGKHFRTV THGMWPFKLA PPAGGMRQKR RHFVEGGDYG NR DTLINRF LARMI UniProtKB: Putative 60S ribosomal protein L7

+
Macromolecule #74: 60S ribosomal protein L30

Macromolecule	Name: 60S ribosomal protein L30 / type: protein_or_peptide / ID: 74 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 11.370224 KDa
Sequence	String: MAKKTKSKVD TINAKLQLVM KSGKYVLGTQ QALTTLRQGR SKLVVIANNC PPIRRAEVEY YCTLSKTPIH HYSGNNLDLG TACGKHFRT CVLSVTNVGD SDIAA UniProtKB: 60S ribosomal protein L30

+
Macromolecule #75: Putative 60S ribosomal subunit protein L31

Macromolecule	Name: Putative 60S ribosomal subunit protein L31 / type: protein_or_peptide / ID: 75 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 21.316254 KDa
Sequence	String: MTRAGMKGKV LGKEKKAAII DARKKAAESR KNRDDKRWKR VLANMDEEKR KKFHGVGNTA KNSRVRGATR ASLLKRTGRK PDAVSMEAT IHLSKLLKKK TFSKRAPLAI KRIKAFVGRL MKTKDNRIDA SLNTYIWHKG VKGVPGRVRV LIQRKSETTE G NKHKHFYT VISNVPVASF KGLTTKTVEQ UniProtKB: Putative 60S ribosomal subunit protein L31

+
Macromolecule #76: 60S ribosomal protein L32

Macromolecule	Name: 60S ribosomal protein L32 / type: protein_or_peptide / ID: 76 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 15.458153 KDa
Sequence	String: MVKPTVSKAI VKKRTKRFTR HRYELFPQLS SSWRKPRGED SPVRRRYKGQ KAMPNKGYGS DRATKYITPS GFRNFPINNV EDLYMLVMQ NRKYAGVISH TVGARKRKAI VRKAMELDVR LANGNAKLRK IANQ UniProtKB: 60S ribosomal protein L32

+
Macromolecule #77: Putative ribosomal protein l35a

Macromolecule	Name: Putative ribosomal protein l35a / type: protein_or_peptide / ID: 77 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 16.492312 KDa
Sequence	String: MTTSKVHSQR SKKLHQLSAK TSRVNRNRKA PRLYMKGTLA GYTRGLHGQT KQTALVRVEN VNTREDATWY VGKRVCYVYH GKKVKRCVR WSKAPARRST TRALWGRVTR PHGNAGMMRV KFNGASVPAS AIGRRIRVYL YPSQI UniProtKB: Putative ribosomal protein l35a

+
Macromolecule #78: Putative 60S ribosomal protein L34

Macromolecule	Name: Putative 60S ribosomal protein L34 / type: protein_or_peptide / ID: 78 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 19.335119 KDa
Sequence	String: MSCPRVQYRR RMHYATRGNR MKMVRTPGNK LVMQKRAKRS QGIHTPWVLG HKRLGGTKAL RHIDARLASR HEKSVSRAYG GVLSHDQVR DRVVRAFLVE EQRIVKQALK EHSKMKLSHK RTANKKKSKQ SKKEAIAKKI STKTVSKKKV PAKKATTTRQ P VGSKLVKK UniProtKB: Putative 60S ribosomal protein L34

+
Macromolecule #79: Putative 60S Ribosomal protein L36

Macromolecule	Name: Putative 60S Ribosomal protein L36 / type: protein_or_peptide / ID: 79 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 11.9752 KDa
Sequence	String: MSAPTPRTGI IAGFNKGHVT TRRPRQPSPN DRFAVPHKHL RAVKAIIADL VGLSPLEKRV QEFLRVGKEK RALKYCKKRL GDFTAAKKK RSKMEEALRH ATKKHH UniProtKB: Putative 60S Ribosomal protein L36

+
Macromolecule #80: Ribosomal protein L37

Macromolecule	Name: Ribosomal protein L37 / type: protein_or_peptide / ID: 80 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 9.86259 KDa
Sequence	String: MTKGTTSMGQ RHGRTHILCR RCGRNSYHVQ WERCAACAYP RASRRRYNWS VKAIKRRRTG TGRCRYLKVV NRRIANHFKT PKA UniProtKB: Ribosomal protein L37

+
Macromolecule #81: Putative ribosomal protein L38

Macromolecule	Name: Putative ribosomal protein L38 / type: protein_or_peptide / ID: 81 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 9.479287 KDa
Sequence	String: MPREIKTLKE FLAICSRKDA RCVKVKHNPS ATKFKVRCSR YLYTLVVNDK KKADKIERSI HPSVKKIAVT ARSHAKTNAG SKQ UniProtKB: Putative ribosomal protein L38

+
Macromolecule #82: Putative 60S ribosomal protein L39

Macromolecule	Name: Putative 60S ribosomal protein L39 / type: protein_or_peptide / ID: 82 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 6.504845 KDa
Sequence	String: MGRFKPLAVK KKYAKKMNQN KPVPYWIRLR TGNRIKWNEK RRHWRRTKLN Y UniProtKB: Putative 60S ribosomal protein L39

+
Macromolecule #83: Ubiquitin-60S ribosomal protein L40

Macromolecule	Name: Ubiquitin-60S ribosomal protein L40 / type: protein_or_peptide / ID: 83 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 14.711425 KDa
Sequence	String: MQIFVKTLTG KTIALEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EEGRTLSDYN IQKESTLHLV LRLRGGVMEP TLVALAKKY NWEKKVCRRC YARLPVRATN CRKKACGHCS NLRMKKKLR UniProtKB: Ubiquitin-ribosomal protein eL40 fusion protein

+
Macromolecule #84: 60S ribosomal protein L41

Macromolecule	Name: 60S ribosomal protein L41 / type: protein_or_peptide / ID: 84 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 4.390496 KDa
Sequence	String: MGTVSRPRGM RPKWHKKRIK RLKLRRRRMR QRSK

+
Macromolecule #85: 60S ribosomal protein L37a

Macromolecule	Name: 60S ribosomal protein L37a / type: protein_or_peptide / ID: 85 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 10.337223 KDa
Sequence	String: MAKRTVKMGV MGRYGTRYGA NPRKRAKKLE VSQHAKHFCS FCGKFAFRRK AVGIWRCDGC SKTVAGGAYT LSTPNNSTVR STVRRLREL AKI UniProtKB: 60S ribosomal protein L37a

+
Macromolecule #86: Putative 60S ribosomal protein L44

Macromolecule	Name: Putative 60S ribosomal protein L44 / type: protein_or_peptide / ID: 86 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)	Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weight	Theoretical: 12.302685 KDa
Sequence	String: MVNYPKKKVM HCGDARCNAH KSFKVVQYKA GKARLFARGK RRYDRKQSGY GGQTKPVFHK KAKTTKKIVL KLQCSGCKSI RQVVLKRTK HFELNDKKKT GNKDPTW UniProtKB: Putative 60S ribosomal protein L44

+
Macromolecule #87: MAGNESIUM ION

+
Macromolecule #88: SODIUM ION

+
Macromolecule #89: POTASSIUM ION

+
Macromolecule #90: ZINC ION

+
Macromolecule #91: water

-
Experimental details

-
Structure determination

Method	cryo EM
Processing	single particle reconstruction
Aggregation state	particle

-
Sample preparation

Buffer	pH: 7.6
Grid	Model: Quantifoil R2/2 / Material: COPPER / Support film - Material: CARBON / Support film - topology: HOLEY
Vitrification	Cryogen name: ETHANE

-
Electron microscopy

Microscope	FEI TITAN KRIOS
Image recording	Film or detector model: GATAN K3 BIOQUANTUM (6k x 4k) / Average electron dose: 0.94 e/Å²
Electron beam	Acceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
Electron optics	Illumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELD / Nominal defocus max: 1.3 µm / Nominal defocus min: 0.7000000000000001 µm
Experimental equipment	Model: Titan Krios / Image courtesy: FEI Company

+
Image processing

Startup model	Type of model: EMDB MAP EMDB ID: 17216
Final reconstruction	Resolution.type: BY AUTHOR / Resolution: 2.43 Å / Resolution method: FSC 0.143 CUT-OFF / Number images used: 178107
Initial angle assignment	Type: MAXIMUM LIKELIHOOD
Final angle assignment	Type: MAXIMUM LIKELIHOOD
FSC plot (resolution estimation)

+
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Macromolecule	Name: MAGNESIUM ION / type: ligand / ID: 87 / Number of copies: 219 / Formula: MG
Molecular weight	Theoretical: 24.305 Da

Macromolecule	Name: SODIUM ION / type: ligand / ID: 88 / Number of copies: 34
Molecular weight	Theoretical: 22.99 Da

Macromolecule	Name: POTASSIUM ION / type: ligand / ID: 89 / Number of copies: 16 / Formula: K
Molecular weight	Theoretical: 39.098 Da

Macromolecule	Name: ZINC ION / type: ligand / ID: 90 / Number of copies: 1 / Formula: ZN
Molecular weight	Theoretical: 65.409 Da

Macromolecule	Name: water / type: ligand / ID: 91 / Number of copies: 2465 / Formula: HOH
Molecular weight	Theoretical: 18.015 Da
Chemical component information	ChemComp-HOH: WATER

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-Supplemental data

-Additional map: Consensus map

-Sample components

+Entire : CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mu...

+Supramolecule #1: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : LM32Cs1C1 mu...

+Macromolecule #1: LSUa_rRNA_chain_1

+Macromolecule #2: LSUb_rRNA_chain_2

+Macromolecule #3: SR1_chain_3

+Macromolecule #4: SR2_chain_4

+Macromolecule #5: SR4_chain_5

+Macromolecule #6: SR6_chain_6

+Macromolecule #7: 5.8S_rRNA_chain_7

+Macromolecule #8: 5S_rRNA_chain_8

+Macromolecule #28: SSU_rRNA_chain_S1

+Macromolecule #29: E-site_tRNA_chain_S4

+Macromolecule #9: Putative 60S ribosomal protein L2

+Macromolecule #10: Putative ribosomal protein L3

+Macromolecule #11: Putative ribosomal protein L1a

+Macromolecule #12: 60S ribosomal protein L11

+Macromolecule #13: Putative 60S ribosomal protein L9

+Macromolecule #14: Putative 60S ribosomal protein L6

+Macromolecule #15: 60S ribosomal protein L7a

+Macromolecule #16: Putative 60S ribosomal protein L13a

+Macromolecule #17: Putative 60S ribosomal protein L13

+Macromolecule #18: Putative 60S ribosomal protein L23

+Macromolecule #19: Putative 40S ribosomal protein L14

+Macromolecule #20: Putative 60S ribosomal protein L27A/L29

+Macromolecule #21: Ribosomal protein L15

+Macromolecule #22: Putative 60S ribosomal protein L10

+Macromolecule #23: Putative 60S ribosomal protein L5

+Macromolecule #24: 60S ribosomal protein L18

+Macromolecule #25: Putative 60S ribosomal protein L19

+Macromolecule #26: 60S ribosomal protein L18a

+Macromolecule #27: Putative 60S ribosomal protein L21

+Macromolecule #30: 40S ribosomal protein S3a

+Macromolecule #31: 40S ribosomal protein SA

+Macromolecule #32: Putative 40S ribosomal protein S3

+Macromolecule #33: Putative 40S ribosomal protein S9

+Macromolecule #34: 40S ribosomal protein S4

+Macromolecule #35: 40S ribosomal protein S2

+Macromolecule #36: 40S ribosomal protein S6

+Macromolecule #37: 40S ribosomal protein S5

+Macromolecule #38: 40S ribosomal protein S7

+Macromolecule #39: Putative 40S ribosomal protein S15A

+Macromolecule #40: 40S ribosomal protein S8

+Macromolecule #41: Putative 40S ribosomal protein S16

+Macromolecule #42: Putative ribosomal protein S20

+Macromolecule #43: Putative 40S ribosomal protein S10

+Macromolecule #44: 40S ribosomal protein S14

+Macromolecule #45: Putative 40S ribosomal protein S23

+Macromolecule #46: 40S ribosomal protein S12

+Macromolecule #47: Putative 40S ribosomal protein S18

+Macromolecule #48: Putative ribosomal protein S29

+Macromolecule #49: Putative 40S ribosomal protein S13

+Macromolecule #50: Putative 40S ribosomal protein S11

+Macromolecule #51: Putative 40S ribosomal protein S17

+Macromolecule #52: Putative 40S ribosomal protein S15

+Macromolecule #53: 40S ribosomal protein S19-like protein

+Macromolecule #54: Putative 40S ribosomal protein S21

+Macromolecule #55: 40S ribosomal protein S24

+Macromolecule #56: 40S ribosomal protein S25

+Macromolecule #57: 40S ribosomal protein S26

+Macromolecule #58: Putative 40S ribosomal protein S27-1

+Macromolecule #59: Putative 40S ribosomal protein S33

+Macromolecule #60: 40S ribosomal protein S30

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