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- EMDB-17216: CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN -

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Basic information

Entry
Database: EMDB / ID: EMD-17216
TitleCRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN
Map data
Sample
  • Complex: 80S RIBOSOME FROM LEISHMANIA MAJOR
    • RNA: x 10 types
    • Protein or peptide: x 75 types
  • Ligand: x 5 types
KeywordsCRYO-EM LEISHMANIA MAJOR 80S RIBOSOME WILD TYPE / RIBOSOME
Function / homology
Function and homology information


ciliary transition zone / nuclear lumen / ciliary plasm / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / protein-RNA complex assembly / translation regulator activity / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of LSU-rRNA / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / rescue of stalled ribosome ...ciliary transition zone / nuclear lumen / ciliary plasm / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / protein-RNA complex assembly / translation regulator activity / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of LSU-rRNA / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / rescue of stalled ribosome / ribosomal large subunit biogenesis / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of SSU-rRNA / small-subunit processome / protein kinase C binding / maintenance of translational fidelity / modification-dependent protein catabolic process / protein tag activity / rRNA processing / ribosomal small subunit biogenesis / small ribosomal subunit rRNA binding / ribosome biogenesis / ribosome binding / kinase activity / ribosomal small subunit assembly / small ribosomal subunit / 5S rRNA binding / large ribosomal subunit rRNA binding / cytosolic small ribosomal subunit / ribosomal large subunit assembly / cytoplasmic translation / cytosolic large ribosomal subunit / negative regulation of translation / rRNA binding / ribosome / protein ubiquitination / structural constituent of ribosome / positive regulation of protein phosphorylation / ribonucleoprotein complex / translation / mRNA binding / ubiquitin protein ligase binding / nucleolus / RNA binding / zinc ion binding / nucleoplasm / nucleus / metal ion binding / cytosol / cytoplasm
Similarity search - Function
: / Ribosomal protein L28e / Ribosomal protein L23 / : / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / Ribosomal protein L18e / Ribosomal protein 60S L18 and 50S L18e / Ribosomal protein S26e / Ribosomal protein S26e superfamily ...: / Ribosomal protein L28e / Ribosomal protein L23 / : / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / Ribosomal protein L18e / Ribosomal protein 60S L18 and 50S L18e / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein S12e / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein S2, eukaryotic / Small (40S) ribosomal subunit Asc1/RACK1 / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / 40S Ribosomal protein S10 / Ribosomal protein S10, eukaryotic/archaeal / Ribosomal protein L44e signature. / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein L10e / Ribosomal protein L13e / Ribosomal protein L13e / Ribosomal protein L19, eukaryotic / Ribosomal protein S2, eukaryotic/archaeal / Ribosomal protein S8e subdomain, eukaryotes / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein S30 / Ribosomal protein S30 / 40S ribosomal protein S29/30S ribosomal protein S14 type Z / : / Ribosomal protein S3, eukaryotic/archaeal / Ribosomal protein L44e / Ribosomal protein L44 / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein S19e / Ribosomal protein S19e / Ribosomal protein L30e signature 1. / Ribosomal_S19e / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal L40e family / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / 40S ribosomal protein S4, C-terminal domain / 40S ribosomal protein S4 C-terminus / Ribosomal_L40e / Ribosomal protein L40e / Ribosomal protein L40e superfamily / Ribosomal protein S8e, conserved site / Ribosomal protein S8e signature. / Ribosomal protein L30e signature 2. / Ribosomal protein S19A/S15e / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal protein L30e, conserved site / Ribosomal protein L27e / Ribosomal protein L27e superfamily / Ribosomal L27e protein family / Ribosomal protein L39e, conserved site / Ribosomal protein L39e signature. / Ribosomal protein S17e / Ribosomal protein S17e-like superfamily / Ribosomal S17 / : / Ribosomal protein S6, eukaryotic / Ribosomal S24e conserved site / Ribosomal protein S24e signature. / Ribosomal protein L34Ae / Ribosomal protein L34e / 40S ribosomal protein S1/3, eukaryotes / Ribosomal protein L14e domain / Ribosomal protein S4e, N-terminal / 60S ribosomal protein L19 / Ribosomal protein L14 / RS4NT (NUC023) domain / Ribosomal protein L30/YlxQ / Ribosomal Protein L6, KOW domain / Ribosomal protein S7e / Ribosomal protein L7A/L8 / Ribosomal protein S7e / Ribosomal protein L13, eukaryotic/archaeal / 60S ribosomal protein L35 / Ribosomal protein L6e / Ribosomal protein S4, KOW domain / Ribosomal protein S4e
Similarity search - Domain/homology
40S ribosomal protein S7 / Putative ribosomal protein L1a / Putative 60S ribosomal protein L13 / 40S ribosomal protein S19-like protein / Ribosomal protein L37 / 60S ribosomal protein L30 / Putative 60S ribosomal protein L5 / Putative 60S ribosomal subunit protein L31 / Putative 60S ribosomal protein L27A/L29 / Putative 60S ribosomal protein L23 ...40S ribosomal protein S7 / Putative ribosomal protein L1a / Putative 60S ribosomal protein L13 / 40S ribosomal protein S19-like protein / Ribosomal protein L37 / 60S ribosomal protein L30 / Putative 60S ribosomal protein L5 / Putative 60S ribosomal subunit protein L31 / Putative 60S ribosomal protein L27A/L29 / Putative 60S ribosomal protein L23 / Putative 60S ribosomal protein L10 / Small ribosomal subunit protein eS8 / Large ribosomal subunit protein uL5 / Ubiquitin-ribosomal protein eL40 fusion protein / Putative 60S ribosomal protein L2 / Small ribosomal subunit protein eS1 / Small ribosomal subunit protein uS2 / Large ribosomal subunit protein eL22 / Putative 40S ribosomal protein S27-1 / 60S ribosomal protein L29 / 40S ribosomal protein S24 / Putative ribosomal protein L24 / Putative 40S ribosomal protein S10 / Ribosomal protein S18 / Ribosomal protein L3 / Putative 60S ribosomal protein L44 / Putative 40S ribosomal protein S13 / 40S ribosomal protein S3 / Putative 60S ribosomal protein L6 / Putative ribosomal protein L27 / 60S ribosomal protein L18a / Putative RNA binding protein / Ribosomal protein L15 / 40S ribosomal protein S30 / Activated protein kinase c receptor / Putative 40S ribosomal protein S17 / Putative ribosomal protein S29 / Putative ribosomal protein S20 / 40S ribosomal protein S14 / 40S ribosomal protein S26 / Putative 60S ribosomal protein L35 / Putative ribosomal protein L38 / Putative 40S ribosomal protein S33 / Ribosomal protein S16 / Putative 60S ribosomal protein L7 / 40S ribosomal protein S25 / Putative 60S ribosomal protein L26 / Putative 60S ribosomal protein L17 / Putative 40S ribosomal protein L14 / Putative 40S ribosomal protein S15 / 60S ribosomal protein L37a / 60S ribosomal protein L32 / Putative 40S ribosomal protein S23 / Putative 60S ribosomal protein L9 / Putative 60S Ribosomal protein L36 / 40S ribosomal protein S2 / Large ribosomal subunit protein eL34 / Putative 60S ribosomal protein L39 / Putative 60S ribosomal protein L21 / Putative 60S ribosomal protein L13a / 40S ribosomal protein S4 / 40S ribosomal protein S12 / Large ribosomal subunit protein eL18 / Putative 40S ribosomal protein S15A / Large ribosomal subunit protein eL28 / Putative 40S ribosomal protein S21 / Putative ribosomal protein l35a / Putative 40S ribosomal protein S9 / 60S ribosomal protein L7a / Putative 60S ribosomal protein L23a / Putative 60S ribosomal protein L19 / 40S ribosomal protein S5 / Small ribosomal subunit protein eS6
Similarity search - Component
Biological speciesLeishmania major strain Friedlin (eukaryote)
Methodsingle particle reconstruction / cryo EM / Resolution: 2.4 Å
AuthorsRajan KS / Yonath A
Funding supportEuropean Union, 1 items
OrganizationGrant numberCountry
European Research Council (ERC)European Union
CitationJournal: Cell Rep / Year: 2024
Title: Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Authors: K Shanmugha Rajan / Saurav Aryal / Disha-Gajanan Hiregange / Anat Bashan / Hava Madmoni / Mika Olami / Tirza Doniger / Smadar Cohen-Chalamish / Pascal Pescher / Masato Taoka / Yuko Nobe / ...Authors: K Shanmugha Rajan / Saurav Aryal / Disha-Gajanan Hiregange / Anat Bashan / Hava Madmoni / Mika Olami / Tirza Doniger / Smadar Cohen-Chalamish / Pascal Pescher / Masato Taoka / Yuko Nobe / Aliza Fedorenko / Tanaya Bose / Ella Zimermann / Eric Prina / Noa Aharon-Hefetz / Yitzhak Pilpel / Toshiaki Isobe / Ron Unger / Gerald F Späth / Ada Yonath / Shulamit Michaeli /
Abstract: Leishmania is the causative agent of cutaneous and visceral diseases affecting millions of individuals worldwide. Pseudouridine (Ψ), the most abundant modification on rRNA, changes during the ...Leishmania is the causative agent of cutaneous and visceral diseases affecting millions of individuals worldwide. Pseudouridine (Ψ), the most abundant modification on rRNA, changes during the parasite life cycle. Alterations in the level of a specific Ψ in helix 69 (H69) affected ribosome function. To decipher the molecular mechanism of this phenotype, we determine the structure of ribosomes lacking the single Ψ and its parental strain at ∼2.4-3 Å resolution using cryo-EM. Our findings demonstrate the significance of a single Ψ on H69 to its structure and the importance for its interactions with helix 44 and specific tRNAs. Our study suggests that rRNA modification affects translation of mRNAs carrying codon bias due to selective accommodation of tRNAs by the ribosome. Based on the high-resolution structures, we propose a mechanism explaining how the ribosome selects specific tRNAs.
History
DepositionApr 26, 2023-
Header (metadata) releaseMay 8, 2024-
Map releaseMay 8, 2024-
UpdateOct 16, 2024-
Current statusOct 16, 2024Processing site: PDBe / Status: Released

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Structure visualization

Supplemental images

emd_17216.png

Downloads & links

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Map

FileDownload / File: emd_17216.map.gz / Format: CCP4 / Size: 421.9 MB / Type: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
Projections & slices

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AxesZ (Sec.)X (Row.)Y (Col.)
0.85 Å/pix.
x 480 pix.
= 408. Å		0.85 Å/pix.
x 480 pix.
= 408. Å		0.85 Å/pix.
x 480 pix.
= 408. Å

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Images are generated by Spider.

Voxel sizeX=Y=Z: 0.85 Å
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Histogram (log scale)
Contour LevelBy AUTHOR: 0.01
Minimum - Maximum-0.036841728 - 0.16196197
Average (Standard dev.)0.0005472919 (±0.00406818)
SymmetrySpace group: 1
Details

EMDB XML:

Map geometry
Axis orderYXZ
Origin000
Dimensions480480480
Spacing480480480
CellA=B=C: 408.0 Å
α=β=γ: 90.0 °

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Supplemental data

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Additional map: #1

Fileemd_17216_additional_1.map
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Half map: #1

Fileemd_17216_half_map_1.map
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Half map: #2

Fileemd_17216_half_map_2.map
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Sample components

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Entire : 80S RIBOSOME FROM LEISHMANIA MAJOR

EntireName: 80S RIBOSOME FROM LEISHMANIA MAJOR
Components
  • Complex: 80S RIBOSOME FROM LEISHMANIA MAJOR
    • RNA: LSUa_rRNA_chain_1
    • RNA: SR1_chain_3
    • RNA: SR2_chain_4
    • RNA: SR4_chain_5
    • RNA: SR6_chain_6
    • RNA: 5.8S_rRNA_chain_7
    • RNA: 5S_rRNA_chain_8
    • Protein or peptide: Putative 60S ribosomal protein L2
    • Protein or peptide: Putative ribosomal protein L3
    • Protein or peptide: Putative ribosomal protein L1a
    • Protein or peptide: 60S ribosomal protein L11
    • Protein or peptide: Putative 60S ribosomal protein L9
    • Protein or peptide: Putative 60S ribosomal protein L6
    • Protein or peptide: 60S ribosomal protein L7a
    • Protein or peptide: Putative 60S ribosomal protein L13a
    • Protein or peptide: Putative 60S ribosomal protein L13
    • Protein or peptide: Putative 60S ribosomal protein L23
    • Protein or peptide: Putative 40S ribosomal protein L14
    • Protein or peptide: Putative 60S ribosomal protein L27A/L29
    • Protein or peptide: Ribosomal protein L15
    • Protein or peptide: Putative 60S ribosomal protein L10
    • Protein or peptide: Putative 60S ribosomal protein L5
    • Protein or peptide: 60S ribosomal protein L18
    • Protein or peptide: Putative 60S ribosomal protein L19
    • Protein or peptide: 60S ribosomal protein L18a
    • RNA: SSU_rRNA_chain_S1
    • RNA: E-site_tRNA_chain_S4
    • Protein or peptide: 40S ribosomal protein S3a
    • Protein or peptide: 40S ribosomal protein SA
    • Protein or peptide: Putative 40S ribosomal protein S3
    • Protein or peptide: Putative 40S ribosomal protein S9
    • Protein or peptide: 40S ribosomal protein S4
    • Protein or peptide: 40S ribosomal protein S2
    • Protein or peptide: 40S ribosomal protein S6
    • Protein or peptide: 40S ribosomal protein S5
    • Protein or peptide: 40S ribosomal protein S7
    • Protein or peptide: 40S ribosomal protein S8
    • Protein or peptide: Putative 40S ribosomal protein S16
    • Protein or peptide: Putative ribosomal protein S20
    • Protein or peptide: Putative 40S ribosomal protein S10
    • Protein or peptide: 40S ribosomal protein S14
    • Protein or peptide: Putative 40S ribosomal protein S23
    • Protein or peptide: 40S ribosomal protein S12
    • Protein or peptide: Putative 40S ribosomal protein S18
    • Protein or peptide: Putative ribosomal protein S29
    • Protein or peptide: Putative 40S ribosomal protein S13
    • Protein or peptide: Putative 40S ribosomal protein S11
    • Protein or peptide: Putative 40S ribosomal protein S17
    • Protein or peptide: Putative 40S ribosomal protein S15
    • Protein or peptide: 40S ribosomal protein S19-like protein
    • Protein or peptide: Putative 40S ribosomal protein S21
    • Protein or peptide: 40S ribosomal protein S24
    • Protein or peptide: Putative 60S ribosomal protein L21
    • Protein or peptide: 40S ribosomal protein S25
    • Protein or peptide: Putative 40S ribosomal protein S27-1
    • Protein or peptide: 40S ribosomal protein S26
    • Protein or peptide: Putative 40S ribosomal protein S33
    • Protein or peptide: 40S ribosomal protein S30
    • Protein or peptide: Guanine nucleotide-binding protein subunit beta-like protein
    • Protein or peptide: Putative RNA binding protein
    • Protein or peptide: Putative 40S ribosomal protein S15A
    • Protein or peptide: Putative 60S ribosomal protein L17
    • Protein or peptide: Putative 60S ribosomal protein L22
    • Protein or peptide: Putative 60S ribosomal protein L23a
    • Protein or peptide: Putative 60S ribosomal protein L26
    • Protein or peptide: Putative ribosomal protein L24
    • Protein or peptide: 60S ribosomal protein L27
    • Protein or peptide: Putative 60S ribosomal protein L28
    • Protein or peptide: Putative 60S ribosomal protein L35
    • Protein or peptide: 60S ribosomal protein L29
    • Protein or peptide: Putative 60S ribosomal protein L7
    • Protein or peptide: 60S ribosomal protein L30
    • Protein or peptide: Putative 60S ribosomal subunit protein L31
    • Protein or peptide: 60S ribosomal protein L32
    • Protein or peptide: Putative ribosomal protein l35a
    • Protein or peptide: Putative 60S ribosomal protein L34
    • Protein or peptide: Putative 60S Ribosomal protein L36
    • Protein or peptide: Ribosomal protein L37
    • Protein or peptide: Putative ribosomal protein L38
    • Protein or peptide: Putative 60S ribosomal protein L39
    • Protein or peptide: Ubiquitin-60S ribosomal protein L40
    • Protein or peptide: 60S ribosomal protein L41
    • Protein or peptide: 60S ribosomal protein L37a
    • Protein or peptide: Putative 60S ribosomal protein L44
    • RNA: LSUb_rRNA_chain_2
  • Ligand: MAGNESIUM ION
  • Ligand: POTASSIUM ION
  • Ligand: SODIUM ION
  • Ligand: ZINC ION
  • Ligand: water

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Supramolecule #1: 80S RIBOSOME FROM LEISHMANIA MAJOR

SupramoleculeName: 80S RIBOSOME FROM LEISHMANIA MAJOR / type: complex / ID: 1 / Parent: 0 / Macromolecule list: #1-#85
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)

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Macromolecule #1: LSUa_rRNA_chain_1

MacromoleculeName: LSUa_rRNA_chain_1 / type: rna / ID: 1 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 577.0465 KDa
SequenceString: ACAGACCUGA GUGUGGCAGG ACUACCCGCC GAACUUAAGC AUAUUACUCA GCGGAGGAAA AGAAAACAAC CGUGAUUCUC UCAGUGAGC GGCGAGCGAA GAGGGAACGA ACUCGUUGCC GAAUCGGGUC UUACAAGGCC UUGAGUUGUG GCACAAAUAU C AUUGUGUG ...String:
ACAGACCUGA GUGUGGCAGG ACUACCCGCC GAACUUAAGC AUAUUACUCA GCGGAGGAAA AGAAAACAAC CGUGAUUCUC UCAGUGAGC GGCGAGCGAA GAGGGAACGA ACUCGUUGCC GAAUCGGGUC UUACAAGGCC UUGAGUUGUG GCACAAAUAU C AUUGUGUG GUUGGUGCAG GAGUGGCGAA AUUCAAGCGA AAAGCAAACC CGUUGCUGAA UACAACCCUU CAUGUG(A2M)G U A(PSU)UGAGCCAA AGAAGGUGUU AGCCCAUUGA GCCAUAAACC UGAGCGCCUC AUGAACUGUA UUAAGCG(A2M)GU A GCACUGUU UGGGAAUGCA GUGUCAAGUU GGCAGGUAUU UGUCUGCCAA AGUUAAAUAC AGAGUAGGAA GACCGAUAGC GA ACAAGUA GCGUGAGCGA A(A2M)GUUUGAAA AGCACU(PSU)UGG AAAGAGAGUG AAAUAGAACC UGAAGUCGUG ACAAA GACA AUGGAAGUAC CUCCAUUUCA ACGGCCAGAA CCAGCCCUAC UGCAUUAUCC UGUCGGGGAU CAAAAUCCGG CGGGCA ACG AAGUGCAAGA AUCUUGGGUC UUGGUGAAAU GAGCGGAGUA UUUGUGCUGC GCACGGCGCA AGCCGCACGC ACUGGUU UC UUCUCCGUGA UGCUCCAUGU UGGCGAUGGA AAUGGGGUGC CCCCACCCG(PSU) CUUG(1MA)(A2M)AC(A2M)C GG ACCAAGG AGU(OMC)A(A2M)ACAG ACGCGCAAGG GAGGAGAUAU GGUUGCCAGU ACUUCUCUCG UACUGAAAGG GAGAU GCAA AAUGCAUCUG UGGUGUGCAC ACGUCAAAUC CGUUUGAUUU GCCCAACACC GACCGGCCCU CCGUGGGUUG CGUUGG AGU GUGCC(OMU)G(OMU)UU GGACCC(OMG)A(A2M)A GGUGGUGAAC (PSU)AUGCCUGAA CAAGGUGAAG CCCGGGG AA ACCCAGGUGG AGGCCUGUAG CGAUGCUG(A2M)C GUGCAAAUCG C(PSU)CGUAUGAU UUGGGU(A2M)UCG (OMG)A GCGAAAG ACUCAUCGAA CCACCUAGUA GCUGGUUCAC AUCGAAGUUU CC(OMC)(PSU)CAGGA(PSU) AGCUGGUGCU A GUAGAAGU AU(PSU)GUGCGGU AAAGCAAAUG AUUAGAGGCA UUGGUGUUCU UAGAAUAUCG ACCUAUUCUC AAACUUUA A A(OMU)GUGCAAAC AAACCGUGCC UUAGCCAACU GCAAGGCCGG AAAGAAAAGA AUUAGAGGCA CCAAG(PSU)GGGC C UUCU(PSU)CGG UAAGC(OMG)GAGC AGGCGAUGCG GAAUGAACCG CUUAGGGAUA UGUGGCGUCA AAACUUAUGG GCUC AUUCU CGAUACGUGA AAAGGGUGUU GGUGGAUAUG GACAGUUGGA CGGUGGCCAU GGAAGUCGGC AUCCGCUAAG GAGUG UGUA ACAACUCACC AACCGAAUCC ACCGGCCCCG AAAAUGGA(OMU)G ACGCUUAAGC CCAAUUAGUG AUUGCCCAU (PSU)AUUCCUUUG GUAAGGGCGG AAACAAAUCU UGGAGAAAGU GUAGCCCUUC CGAUGUAGAU GUGGCCUGGA GGUUAG GAC GAAGCUUAUG GCGUGAGCCU AAGAUGGACC GGCCUCUAGU GCA(OMG)AU(OMC)(PSU)UG GU(PSU)GGCGU (A2M) (OMG)CAAAGAUCU AACGGAGAUA UACUCAACAU GCAACGUUGG AUACUGGAGC GGGGAAGGAU UUCGUGCCAA C GGCACUCG UACACGA(OMG)UU GUUCGGAAAC UGAGCACAAC GUUAUAUCGU (OMU)UUGU(PSU)AGGA AAGUGAAGGU GUGUCGGCG GCAGCUGCUC UCGGGUAGCU GUUCGACUGG CCAUAACUGA AAAGGGGCAA CAGAGAACCU GGGAUUAUAU U CCAAAAAG AAAUUGCAUG UGGGAA

GENBANK: GENBANK: FR796423.1

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Macromolecule #2: SR1_chain_3

MacromoleculeName: SR1_chain_3 / type: rna / ID: 2 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 69.146633 KDa
SequenceString: UAUUAGUGGU AA(OMU)GCGAAAC ACUUGCCAGG UAACAAAUCA AUCCUCCCAC GGUGAGCUUU CUUUUCACCA UAAUCC ACA UCUCCGGCUU UGCUGGGGCU UGGGCCUUUU UACUUCUCGC GUUGUUCGGA GCGGGGGCUC AAGAUUGAAA AAUGCAG CU CUCCCUACGU ...String:
UAUUAGUGGU AA(OMU)GCGAAAC ACUUGCCAGG UAACAAAUCA AUCCUCCCAC GGUGAGCUUU CUUUUCACCA UAAUCC ACA UCUCCGGCUU UGCUGGGGCU UGGGCCUUUU UACUUCUCGC GUUGUUCGGA GCGGGGGCUC AAGAUUGAAA AAUGCAG CU CUCCCUACGU ACUGUCAUUG UUGUGAGUUC UGCGCAUUAA AGCAAAAACC UGGGGUGU

GENBANK: GENBANK: FR796423.1

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Macromolecule #3: SR2_chain_4

MacromoleculeName: SR2_chain_4 / type: rna / ID: 3 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 59.160129 KDa
SequenceString:
GUGGGAUUGU GAAGGGAUCU CGCAGGUAUC GUGAGGGAAG UAUGGGGUAG UACGAGAGGA ACUCCCAUGC CGU(OMG)CC UCU AGUUUCUGGG GUUUGUCGAA CGGCAAGUGC CCCGAAGCCA UCGCACGGUG GUUCUCGGCU GAACGCCUCU AAGCCAG AA GCCAAUCCCA AGACCAGAUG CCCAC

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Macromolecule #4: SR4_chain_5

MacromoleculeName: SR4_chain_5 / type: rna / ID: 4 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 43.479801 KDa
SequenceString:
UUACGUCCCU CUCCAAACGA GAGAACAUGC AUGGGCUGGC AUGAGCGGCA UGCUUCACUC CGGUGGGGCU CGAGGGGCAU UUACGUCCC GAGGCGCUGA ACCUUGAGGC CUGAAAAUUC AUGCUCAGGG ACACCU

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Macromolecule #5: SR6_chain_6

MacromoleculeName: SR6_chain_6 / type: rna / ID: 5 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 23.336938 KDa
SequenceString:
UCAUCGAAUC GCCACCUACA AGACUGGAGC UUGCUCCCUC GAAGGCGCCA AGUAUAUUCA UGAUCACAAG ACA

GENBANK: GENBANK: FR796423.1

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Macromolecule #6: 5.8S_rRNA_chain_7

MacromoleculeName: 5.8S_rRNA_chain_7 / type: rna / ID: 6 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 54.98957 KDa
SequenceString: AACGUG(OMU)CGC GAUGGAUGAC UUGGCUUCCU AUUUCGUUGA AG(A2M)ACGCAGU AAAGUGCGAU AAGUGGUA (PSU) CAAU(PSU)(OMG)CAGA AUCAUUCAAU UACCGAAUCU UUGAACGCAA ACGGCGCAUG GGAGAAGCUC UAUUGUG UC AUCCCCGUGC ...String:
AACGUG(OMU)CGC GAUGGAUGAC UUGGCUUCCU AUUUCGUUGA AG(A2M)ACGCAGU AAAGUGCGAU AAGUGGUA (PSU) CAAU(PSU)(OMG)CAGA AUCAUUCAAU UACCGAAUCU UUGAACGCAA ACGGCGCAUG GGAGAAGCUC UAUUGUG UC AUCCCCGUGC AUGCCAUAUU CUC(A2M)GUGUCG AAC

GENBANK: GENBANK: XR_002460814.1

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Macromolecule #7: 5S_rRNA_chain_8

MacromoleculeName: 5S_rRNA_chain_8 / type: rna / ID: 7 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 39.450398 KDa
SequenceString:
CUUCGAGUAC GACCACACUU GAGUGAAAAC ACCAUAUCCC GUCCGAUUUG UGAAGUUAAG CACUCACAGG CUCAGUUAGU ACUGAGGUC AGUGAUGACU CGGGAACCCU GAGUGCCGUA CUCC

GENBANK: GENBANK: FR796407.1

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Macromolecule #26: SSU_rRNA_chain_S1

MacromoleculeName: SSU_rRNA_chain_S1 / type: rna / ID: 26 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 710.628688 KDa
SequenceString: GAUCUGG(OMU)UG A(PSU)UCUGC(OMC)AG UAGUCAUA(OMU)G CU(PSU)GUUU(OMC)AA GGACUUAGCC AUGCAU GCC UCAGAAUCAC UGCAUUUGCA GGAAUCUGCG CAUGGCUC(A2M)U UAAA(PSU)CAGAC GUAAUCUGCC GCAAAAAUC UUGCGGUUUC ...String:
GAUCUGG(OMU)UG A(PSU)UCUGC(OMC)AG UAGUCAUA(OMU)G CU(PSU)GUUU(OMC)AA GGACUUAGCC AUGCAU GCC UCAGAAUCAC UGCAUUUGCA GGAAUCUGCG CAUGGCUC(A2M)U UAAA(PSU)CAGAC GUAAUCUGCC GCAAAAAUC UUGCGGUUUC CGCAAAAUUG GAUAACUUGG CGAAACGCCA AGCUAAUACA UGAACCAACC GGGUGUUCUC CACUCCAGAC GGUGGGCAA CCAUCGUCGU GAGACGCCCA GCGAAUGAAU GACAGUAAAA CCAAUGCCUU CACUGGCAGU AACACCCAGC A GUGUUGAC UCAAUUCAUU CCGUGCGAAA GCCGGCUUGU UCCGGCGUCU UUUGACGAAC AACUGCCCUA UCAGCUGGUG AU GGCCGUG UAGUGGACUG CCAUGGCGUU GACGGGAGCG GGGGAUUAGG GUUCGAUUCC GGAGAGGGAG CCUGAGAAAU AGC UACCAC (PSU)UCUACGGAG GGCAGCAGGC GCGC(A2M)AAUUG CCCAAUGUCA AAACAAAACG AUGAGGC(A2M)GC GA AAAGAAA UAGAGUUGUC AGUCCAUUUG GAUUGUCAUU UCAAUGGGGG AUAUUUAAAC CCAUCCAAUA UCGAGUAACA AUU GGA(OMG)GA CAAG(PSU)C(PSU)GGU GCCAGCACCC GCGGUAAUUC CAGCUCCAAA AGCGUAUAUU AAUGCUGU (OMU) GCUGUU(A2M)AAG GGUUCGUAGU UGAACUGUGG GCUGUGCAGG UUUGUUCCUG GUCGUCCCGU CCAUGUCGGA U UUGGUGAC CCAGGCCCUU GCAGCCCGUG AACAUUCAAA GAAACAAGAA ACACGGGAGU GGGUCCUUUC CUGAUUUACG CA UGUCAUG CAUGCCAGGG GGCGUCCGUG AUUUUUUACU GUGACUAAAG AAGCGUGACU AAAGCAGUCA UUUGACUUGA AUU AGAAAG CAUGGGAUAA CAAAGGAGCA GCCUCUAGGC UACCGUUUCG GCUUUUGUUG UUUUUAAAGG UCUAUUGGAG AUUA UGGAG CUGUGCGACA AAUGCUUUCC CAUCGCAACU UCGGUUCGGU GUGUGGCGCC UUUGAGGGGU UUAGUGCGUC CGGUG CGAG CUCCGGUUCG UCCGGCCGUA ACGCCUUUUC AACUCACGGC CUCUAGGAAU GAAGGAGGGU AGUUCGGGGG AGAACG UAC UGGGGCGUCA GAGGUGAAAU (PSU)CUUAGACCG CACCAAGACG AACUACAGCG AAGGCA(PSU)UCU UCAAGGAUA CCUUCCUCAA UCAAGAACCA AAGUGUGGAG AUCGAAGAUG A(PSU)UAGAAACC AUUGUAGUCC ACACUGCAAA CGAUGA CAC CCAUGAAUUG GGGAUCUUAU GGGCCGGCCU GCGGCAGGGU UUACCCUGUG UCAGCACCGC GCCCGCUUUU ACCAACU UA CGUAUCUUUU CUAUUCGGCC UUUACCGGCC ACCCACGGGA AUAUCCUCAG CACGUUUUCU GUUUUUUCAC GCGAAAGC U UUGAGGUUAC AGUCUCAGGG GGGAGUACGU UCGCAA(OMG)AGU GAAACUUAAA GAAAUUGACG GAAUGGCACC ACAAG ACGU GGAGCGUGCG GU(PSU)UAAUU(PSU)G AC(C4J)(5MC)AACAC(OMG) GGGAACUUUA CCAGA(PSU)CCGG AC AGGAUGA GGAUUGACAG AUUGAGUGUU CUUUCUCGAU UCCCUGAAUG G(OMU)G(OMG)UGCAUG GCCGCUUAUG GUCGG UG(OMG)A GUGAUUUG(PSU)U UGGUUGAUUC CGUCAACGGA CGAGAUCCAA GCUGCCCAGU AGAAUUCAGA AUUGCCCA U AGGAUAGCAA ACUCAUCGGC GGGUUUUACC CAACGGUGGG CCGCAUUCGG UCGAAUUCUU CUCUGCGGGA UUCCUUUGU AAUUGCACAA GGUGAAAUUU UGGGCAACAG CA(OMG)GUC(OMU)GUG AUGC(PSU)CCUCA AUGUUCUGGG CGACACGC (OMG) (OMC)ACUACAAUG UCA(OMG)UGAGAA CAAGAAAAAC GACUUUUGUC GAACCUACUU GAUCAAAAGA GUGGGGA AA CCCCGGAAUC ACAUAGACCC ACUUGGGACC GAGGAUUGCA AUUA(OMU)UGGUC GCGCAACGAG (7MG)AAUGUCUCG UAGGCGCAG CUCAUCA(A2M)AC UGUGCCGAUU ACGUCCCUGC CA(PSU)U(PSU)GUACA CACCGCC(5MC)GU CGUUG UUUC CGAUGAUGGU GCAAUACAGG UGAUCGGACA GGCGGUGUUU UAUCCGCCCG AAAGUUCACC GAUAUUU(OMC)UU CA AUAGAG(OMG) AAGCAAAAGU CGUAACAAGG UAGCUGUAGG GG(MA6)(MA6)CCUGCA GCUGGGACAU (PSU)UU

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Macromolecule #27: E-site_tRNA_chain_S4

MacromoleculeName: E-site_tRNA_chain_S4 / type: rna / ID: 27 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 6.451926 KDa
SequenceString:
GCGCGGGAGU CCGCGCACCA

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Macromolecule #85: LSUb_rRNA_chain_2

MacromoleculeName: LSUb_rRNA_chain_2 / type: rna / ID: 85 / Number of copies: 1
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 492.500781 KDa
SequenceString: UCCCAACUGC AGACCGUACU CAUCACCGCA UCAGGUCCCC AAGCAUAGAA UGCUC(OMU)GGUA CAUAGAGAAA (OMG)G (OMU)ACAC(PSU)C AGGGAAGUCG GCAAA(A2M)UAGA UGCGUAAGUU CGCAAGAAGC AUUGGCUCUG AGGGCAAAGU C AGAGAAAA ...String:
UCCCAACUGC AGACCGUACU CAUCACCGCA UCAGGUCCCC AAGCAUAGAA UGCUC(OMU)GGUA CAUAGAGAAA (OMG)G (OMU)ACAC(PSU)C AGGGAAGUCG GCAAA(A2M)UAGA UGCGUAAGUU CGCAAGAAGC AUUGGCUCUG AGGGCAAAGU C AGAGAAAA CCGGAAGGCC AGUGUCCUCU CGCAUGCAGC CGUUCUUCAG AUGUUGUUUU GGCGCUCGCC GCCUUAGCAC GC UGAUAGC GACUGUACUG UCGUCUGUGA AGGCUACCUU CCCGAGGCGU CGUAACCCGG CGUCUCACUC UGGCACGGGC CGG UCUUGG CGGGUUCACG CUCGUCUUGU GCCGCGUCCC ACAAAUUGCC AACUCAGAAC UG(OMC)UUACGGC GGGGAAUCCA ACUGU(A2M)UAA UUAAAACAUA GGUUUGUGAU GCAUCCAAGU GGUGUAUAUC GCAAACUGAU U(PSU)CUGCC(OMC)A GUGCUCUGAA UGUCAACGUG ACGAGAU(PSU)CA CCGACGCGCG GGUAAACGGC GGGAGUAACU AUGAC(PSU)C(PSU) C UUAAGGUAGC (5MC)AA(A2M)UGCCUC (OMG)UCUUCCAAU UAGAGACGCG CAUGAA(OMU)GGA UUAAUG(A2M)G (A2M) UUCCCUCUGU (OMC)CCGAGUU(A2M)C (PSU)AUC(PSU)AGCGA A(A2M)CGACAGUC AAGGGAACGG ACU (PSU)G(A2M)AGG GCUAAGCGG(OMG) GAAAGAAGAC CCU(OMG)UUGAGU (PSU)UGAC(OMU)CCAG UCUGGCUCUG UGCGGCGAC AUCUGAGGUG UAGUAUAGGU GGAAGCGCAA GCGCAAAUGA AAUACCACCA CUCGGAACGU UGCUUCACUU A UCGAAUGA AGAGACCAAU GGGUUUAGCG UAGUCUUCGG GCUAUGCACC GUCUAGGUUU GGGAGUAAUU UUAUGGCGGU AA CCCCGUC CCCACGGGAA AGGGUGGUGU GCUUUUUCUG CGUGCGUCUU CACGGGCGUC GCGCGGGCCC CGCUCUUUUU UAU UGCGUU UCCUUCGGGG GGCGUGACUC GUGGGUACCC AACCGUGCUG UAAACUGAAC CAACGGGAUU GCCUCGUGCA GUUC CGGAG UCUUGUUUCG AGACAUCUGC CAGAUGGGGA GUUUGGCUG(OMG) GGCGGCAUAU C(PSU)G(PSU)UACACG ACA ACGCAG G(OMU)(OMG)UCCUAAG GCGAGCUCAG UGGGAACAGA AAUCUCACGU AGAACACAAG CGUAAAAGCU UGCUUG AU(PSU) AACGAUUUCC AGUA(OMC)GAAUC GAGACUGCGA AAGCAAGGCC (A2M)GCGAUCCU(PSU) UGCGAAGAAU A GGAAAUAU GAACAAAUCA UACCA(OMG)A(OMG)GU GUCAGAAUAA UUAC(OMC)ACAG(OMG) GAUAACUGGC (PSU) (PSU)GUGGCGG CCAAGCGUUC AUAGCGACGU CGCUUUUUGA (PSU)CCUU(5MC)GAUG UCGG(OMC)(PSU)CUUC CU AACCUAG CGCCGCAGAA GACGCUAAGG GU(PSU)GGAU(OMU)(OMG)(PSU) UCACCCACUG (A2M)CAGGGAACG (PSU)G(A2M)GCUGGG UUUAGA(OMC)CGU CG(PSU)GAGACAG GU(PSU)GGUUU(OMU)A CCCUACUUAG CUGGAAA UU GCGAGAAAAA GAUUAUCCGU GCAAAGCGGA CGUCGGGUCG UUCUUGGGCC UGGCGAGCGG UGGGUAGUAC AUGGUACG C UCAUCACC

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Macromolecule #8: Putative 60S ribosomal protein L2

MacromoleculeName: Putative 60S ribosomal protein L2 / type: protein_or_peptide / ID: 8 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 28.331891 KDa
SequenceString: MGKTVLSCRK GNGSVYQVHG HKRLGPAKLR ILDYAERHGY MRGVVKSIEH EAGRGAALAR VEFRHPYKFR RVKELMVAPE GMFTGQSVF CGQKAPLAIG NVLPLGQITE GCIVCNVEAK PGDRGTLARA SGDYCIIISH NHETGRTRLK LPSGQKKSVP S TSRAMIGI ...String:
MGKTVLSCRK GNGSVYQVHG HKRLGPAKLR ILDYAERHGY MRGVVKSIEH EAGRGAALAR VEFRHPYKFR RVKELMVAPE GMFTGQSVF CGQKAPLAIG NVLPLGQITE GCIVCNVEAK PGDRGTLARA SGDYCIIISH NHETGRTRLK LPSGQKKSVP S TSRAMIGI ISGGGRIEKP VLKAGNSFYR FRGKRNCWPK VRGVARNPVE HPHGGGNHQH IGHPSTVSRH SPPGQKVGLI AA RRTGRIR GGKAVKGAWH PEE

UniProtKB: Putative 60S ribosomal protein L2

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Macromolecule #9: Putative ribosomal protein L3

MacromoleculeName: Putative ribosomal protein L3 / type: protein_or_peptide / ID: 9 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 47.59366 KDa
SequenceString: MSHCKFEHPR HGHLGFLPRK RSRQIRGRAR AFPKDDATQK PHLTSFMVFK AGMTHIVRDV DRPGSKVNKK EVVEPVTILE APPMVIVGI VGYRQTPVGL KTIGTVWAHH TSVEFRRRYY KNWKQSAQLA FSRQKQFANT KEGKVAEART LNAFAKKASV I RVIAHTQL ...String:
MSHCKFEHPR HGHLGFLPRK RSRQIRGRAR AFPKDDATQK PHLTSFMVFK AGMTHIVRDV DRPGSKVNKK EVVEPVTILE APPMVIVGI VGYRQTPVGL KTIGTVWAHH TSVEFRRRYY KNWKQSAQLA FSRQKQFANT KEGKVAEART LNAFAKKASV I RVIAHTQL RKLRNHRVGV KKAHVQEIQV NGGSVAAKIA LAKSLLEKEV RVDSVFQQSE ACDVCSVTKG HGTEGVVKRW GV ACLPRKT HRGLRKVACI GAWHPARVMY TVARAGQHGY HHRTQLNKKI YQIGRSVAVE PNQATTTYDL TAKTITPMGG FVG YGTVRN DYVMLKGSVS GPRRRVMTLR RPMAPQTSRQ LKEKIVLKFI DTSSKIGHGR FQTKKEKNQW FGPLKKDRIR REER LRKER AARAVERKAK AAKK

UniProtKB: Ribosomal protein L3

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Macromolecule #10: Putative ribosomal protein L1a

MacromoleculeName: Putative ribosomal protein L1a / type: protein_or_peptide / ID: 10 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 41.096855 KDa
SequenceString: MSARPSVSVY SASSDSVVGT CPLPAVFTAP IRSDIVKFVH TNMAKNSRQA YAVNRLSGMN HSAHSWGTGR AVARIPRISG GGTSTSGAG AFGNMCRGGR MFAPTKIFRR WHRKINLHQK RFAVVSALAA SSVPSLVMSR GHQIGNVPEV PLVVEDSIQG Y EKTKEAMA ...String:
MSARPSVSVY SASSDSVVGT CPLPAVFTAP IRSDIVKFVH TNMAKNSRQA YAVNRLSGMN HSAHSWGTGR AVARIPRISG GGTSTSGAG AFGNMCRGGR MFAPTKIFRR WHRKINLHQK RFAVVSALAA SSVPSLVMSR GHQIGNVPEV PLVVEDSIQG Y EKTKEAMA FLKAIAAIDD VNRVNDSREI RAGRGKMRNR RYVARRGPML VMPNNKGTRA FRNIFGLDLA NVSALNLLHL AP GGHVGRF VIWTQSAFEQ LDKIFGTFTE ASAVKKGFTL PAPMLTNTDV TRIMQSEEVR RVLKPKKLQA KKASRFQTPT NGM KNRRLR LRLNPYVKRE TAAAKGMRNV ANRDARRKAK LARVTKAKKA ATKSAKQ

UniProtKB: Putative ribosomal protein L1a

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Macromolecule #11: 60S ribosomal protein L11

MacromoleculeName: 60S ribosomal protein L11 / type: protein_or_peptide / ID: 11 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 21.694502 KDa
SequenceString:
MVAESKAANP MREIVVKKLC INICVGESGD RLTRASKVLE QLCEQTPVLS RARLTVRTFG IRRNEKIAVH CTVRGKKAEE LLEKGLKVK EFELKSYNFA DTGSFGFGID EHIDLGIKYD PSTGIYGMDF YVVLGRRGER VAHRKRKCSR VGHSHHVTKE E AMKWFEKV HDGIIFQAKK KKKMIRRRRR

UniProtKB: Large ribosomal subunit protein uL5

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Macromolecule #12: Putative 60S ribosomal protein L9

MacromoleculeName: Putative 60S ribosomal protein L9 / type: protein_or_peptide / ID: 12 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 21.594295 KDa
SequenceString:
MVKVKSLCTL QIPEGVTVDV KGRKVTVTGK RGTLTKDLTH LQLDLRVDKK NRTFTVIRWF GSKIPIACLN TTKAHVQNMI TGVTKGYRF KVRCAYAHFP INVSVDGQNI EVRNFLGEKR VRRQLVPNTV KVSQTDPSKV KDEIVFDGND LEQVSREAAV L HQMCLVKK KDIRKFLDGI YVQTKTNIEG ME

UniProtKB: Putative 60S ribosomal protein L9

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Macromolecule #13: Putative 60S ribosomal protein L6

MacromoleculeName: Putative 60S ribosomal protein L6 / type: protein_or_peptide / ID: 13 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 21.12674 KDa
SequenceString: MAATKSAVSA AKRKAAKKVS RKSPEYTTLR KSCAPGAIAI ILAGRFRGRR AVILKQLPHN GPLVVSGPMK YNGVPIRRID SRYVIATST TVDISSVDTA PITAEVFQRP KAEKPTKSEG DFMGDKQKAK AEKAAKKTSK AGKKTLVSDA RAQLQKKIDA A LIAAIKKD ...String:
MAATKSAVSA AKRKAAKKVS RKSPEYTTLR KSCAPGAIAI ILAGRFRGRR AVILKQLPHN GPLVVSGPMK YNGVPIRRID SRYVIATST TVDISSVDTA PITAEVFQRP KAEKPTKSEG DFMGDKQKAK AEKAAKKTSK AGKKTLVSDA RAQLQKKIDA A LIAAIKKD AQGKEKAGYL RSVFTVKPGD APHRWNW

UniProtKB: Putative 60S ribosomal protein L6

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Macromolecule #14: 60S ribosomal protein L7a

MacromoleculeName: 60S ribosomal protein L7a / type: protein_or_peptide / ID: 14 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 29.824182 KDa
SequenceString: MPGKEVKKVT QPAKAASPYK KPAVASHFAA RPKNFGIGQD VPYARDLSRF MRWPTFVTMQ RKKRVLQRRL KVPPALNQFT KVLDRASRN EALKLIKKYA PETRKARRER LQKVAEEKKK DPKKTVSTKA PLAVVTGLQE VTRAIEKKQA RMVVIANNVD P VELVLWMP ...String:
MPGKEVKKVT QPAKAASPYK KPAVASHFAA RPKNFGIGQD VPYARDLSRF MRWPTFVTMQ RKKRVLQRRL KVPPALNQFT KVLDRASRN EALKLIKKYA PETRKARRER LQKVAEEKKK DPKKTVSTKA PLAVVTGLQE VTRAIEKKQA RMVVIANNVD P VELVLWMP NLCRANKIPY AIVKDMARLG DAIGRKTATC VALTDVNAED EATLKNLIRS VNARFLSRSD VIRRQWGGLQ LS LRSRAEL RKKHARNAGV DAAAIIQ

UniProtKB: 60S ribosomal protein L7a

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Macromolecule #15: Putative 60S ribosomal protein L13a

MacromoleculeName: Putative 60S ribosomal protein L13a / type: protein_or_peptide / ID: 15 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 25.509248 KDa
SequenceString: MAFPSRKDAF RAQRKGAKKH RPEIIVIDLK DHVLGRAAAV VAKQLLLGKK ITVVRCEQLN IAGTEIRNKI KYLQYLRKRK LTNPTKGPF HHRAPSDVFV RTVRSMLPRY TKRGMKALNS LVAYEGIPPN VVRTGGRVVI PRAQRHVCYR SERPYTVLGN M CKHVGWKY ...String:
MAFPSRKDAF RAQRKGAKKH RPEIIVIDLK DHVLGRAAAV VAKQLLLGKK ITVVRCEQLN IAGTEIRNKI KYLQYLRKRK LTNPTKGPF HHRAPSDVFV RTVRSMLPRY TKRGMKALNS LVAYEGIPPN VVRTGGRVVI PRAQRHVCYR SERPYTVLGN M CKHVGWKY SDVVANLEKA RVEKASRHHE KQAKLRDAWK SARKEALAKM PKHNVEVLKK FGYA

UniProtKB: Putative 60S ribosomal protein L13a

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Macromolecule #16: Putative 60S ribosomal protein L13

MacromoleculeName: Putative 60S ribosomal protein L13 / type: protein_or_peptide / ID: 16 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 24.848982 KDa
SequenceString: MPKGNNAIPH VHQKKHWNPC SSQKGNVKVF LNQPAQKHRR RRLRLLKAKK VFPRPLKALR PQVNCPTVRH NMKRRLGRGF SPAELKAAG LNPQYAATIG IRVDSRRKNK SEEGMNVNVQ RLKTYMSKLV LFPMNHKKVQ KGEASEEEVK AATQDRSRFG D AAVGAVVY ...String:
MPKGNNAIPH VHQKKHWNPC SSQKGNVKVF LNQPAQKHRR RRLRLLKAKK VFPRPLKALR PQVNCPTVRH NMKRRLGRGF SPAELKAAG LNPQYAATIG IRVDSRRKNK SEEGMNVNVQ RLKTYMSKLV LFPMNHKKVQ KGEASEEEVK AATQDRSRFG D AAVGAVVY PSAEAPRAVS AEEKSMCVYA FLKKNHSAVR FFGTRSSRAA RKEAAKEEKT GK

UniProtKB: Putative 60S ribosomal protein L13

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Macromolecule #17: Putative 60S ribosomal protein L23

MacromoleculeName: Putative 60S ribosomal protein L23 / type: protein_or_peptide / ID: 17 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 14.982617 KDa
SequenceString:
MGKDQANVKG CRFRVSVALP VGAVVNCADN TGAKNLYVIS VKGYHGRLNR LPSAALGDMV MCSVKKGKPE LRKKVLNAVI IRQRKSWRR KDGTVIYFED NAGVIVNPKG EMKGSGIAGP VAKESADLWP KISTHAPAIV

UniProtKB: Putative 60S ribosomal protein L23

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Macromolecule #18: Putative 40S ribosomal protein L14

MacromoleculeName: Putative 40S ribosomal protein L14 / type: protein_or_peptide / ID: 18 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 19.948615 KDa
SequenceString:
MVKSHYICAG RLVRILRGPR QDRVGVIVDI VDANRVLVEN PEDAKMWRHV QNLKNVEPLK YCVSVSRNCS AKALKDALAS SKALEKYAK TRTAARVEAK KACAVSTDFE RYQLRVARRS RAHWARKVFD EKDAKTPVSW HKVALKKMLK KAAKMDSTEG A KRRMQKAI AARKAKK

UniProtKB: Putative 40S ribosomal protein L14

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Macromolecule #19: Putative 60S ribosomal protein L27A/L29

MacromoleculeName: Putative 60S ribosomal protein L27A/L29 / type: protein_or_peptide / ID: 19 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 16.135853 KDa
SequenceString:
MPTRFKKCRH QRGSTFCGYG RVGKHRKHES GRGNAGGMHH HRINFDKYHP GYFGKLGMDH YHRKKNPMWK PTINLNNLSR LIAAEEAAK AAKGGTLPVV DLQSSGYAKL LGNGHIQVPC IVKARYVSKL ADKKIRKAGG AVVLQA

UniProtKB: Putative 60S ribosomal protein L27A/L29

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Macromolecule #20: Ribosomal protein L15

MacromoleculeName: Ribosomal protein L15 / type: protein_or_peptide / ID: 20 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 24.497971 KDa
SequenceString: MGAFMYLNEL WKKKSSDVMR FIQRIRSWEF RHQHTVVRLR RPTRPEKARM LGYKTKQGFC VFRVRVRRGG RKRPVHKGIT YGKPKTSGV LGMKLNKNNQ AVAEQRLGKR FGNLRVLNSY WVNMDSTFKW YEVIAVDPMC KTIRRDPRIN WIVNSVHKHR E QRGLTSAG ...String:
MGAFMYLNEL WKKKSSDVMR FIQRIRSWEF RHQHTVVRLR RPTRPEKARM LGYKTKQGFC VFRVRVRRGG RKRPVHKGIT YGKPKTSGV LGMKLNKNNQ AVAEQRLGKR FGNLRVLNSY WVNMDSTFKW YEVIAVDPMC KTIRRDPRIN WIVNSVHKHR E QRGLTSAG RKHRGLRHKG HKASKLRPSY RAAWRRNNRI VFLRKR

UniProtKB: Ribosomal protein L15

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Macromolecule #21: Putative 60S ribosomal protein L10

MacromoleculeName: Putative 60S ribosomal protein L10 / type: protein_or_peptide / ID: 21 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 24.607186 KDa
SequenceString: MARRPSRCYR FCKNKPYPKS RFCRGVPDPK IRNFDIGRRR ATVDEFPVCI HVVSRELEQI ASEALEAARI QANKYMVKRA NKDVFHMRT RAHPFHVLRI NKMLSCAGAD RLQTGMRGAF GKPNGVCARV RIGQILLSMR TKEAYVPQAF EALRRAKMKF P GRQIIVMS ...String:
MARRPSRCYR FCKNKPYPKS RFCRGVPDPK IRNFDIGRRR ATVDEFPVCI HVVSRELEQI ASEALEAARI QANKYMVKRA NKDVFHMRT RAHPFHVLRI NKMLSCAGAD RLQTGMRGAF GKPNGVCARV RIGQILLSMR TKEAYVPQAF EALRRAKMKF P GRQIIVMS KYWGFTNILR TEYEALRDAG KLEQRGTHCK LIAPKGKITM RNVMA

UniProtKB: Putative 60S ribosomal protein L10

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Macromolecule #22: Putative 60S ribosomal protein L5

MacromoleculeName: Putative 60S ribosomal protein L5 / type: protein_or_peptide / ID: 22 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 34.058594 KDa
SequenceString: MPFVKVVKNK AYFKRFQVKY RRRREGKTDY HARRQMVLQD KTKFGSPKYR LVVRITNKDI IAQIVQAKIV GDEVVMAAYA HELPAFGIE HGLTNYAAAY ATGLLLARRT LAKLGIADKF QGAKEADGSY SAVRTKKDDE GDDEERFPFK AILDVGLART T TGARVFGV ...String:
MPFVKVVKNK AYFKRFQVKY RRRREGKTDY HARRQMVLQD KTKFGSPKYR LVVRITNKDI IAQIVQAKIV GDEVVMAAYA HELPAFGIE HGLTNYAAAY ATGLLLARRT LAKLGIADKF QGAKEADGSY SAVRTKKDDE GDDEERFPFK AILDVGLART T TGARVFGV LKGAVDGGMA VPHRPNRFPG YNKEKSSLDA KVHRDRIFGK HVADYLKQVK EEASSNPDEK CVQFSKYMAA KV LPESIEG MYKKAHAAIR ADPSKSLPKK AKKEGVAHKS YKTKKLSGAE KRAAAKAKVA AIRERLGK

UniProtKB: Putative 60S ribosomal protein L5

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Macromolecule #23: 60S ribosomal protein L18

MacromoleculeName: 60S ribosomal protein L18 / type: protein_or_peptide / ID: 23 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 22.07108 KDa
SequenceString: MGVDLTGISK KSRVIRHHTY STNPYIKLLI KLYKFLAKRT SSGFNKVVYQ RLIKSRSNRA PISLSRIAVV MKRKAVFTAK SKAAPIAVV VGDVLDDVRM ARIPAMRVCA LRFSKSARQS IVAAGGECLT FDQLAMIAPT GKNTYLLRGR KSGRESVRHF G ASGVPGSH ...String:
MGVDLTGISK KSRVIRHHTY STNPYIKLLI KLYKFLAKRT SSGFNKVVYQ RLIKSRSNRA PISLSRIAVV MKRKAVFTAK SKAAPIAVV VGDVLDDVRM ARIPAMRVCA LRFSKSARQS IVAAGGECLT FDQLAMIAPT GKNTYLLRGR KSGRESVRHF G ASGVPGSH SKPYATNRGK ETKRGRRTGR SYKRKAFRHV

UniProtKB: Large ribosomal subunit protein eL18

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Macromolecule #24: Putative 60S ribosomal protein L19

MacromoleculeName: Putative 60S ribosomal protein L19 / type: protein_or_peptide / ID: 24 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 28.896115 KDa
SequenceString: MVSLKLQARL ASSILGCGRA RVWLDPNEAV EIQNANSRKS VRKLIKDGFI IRKPVKVHSR ARWRKMKEAK DMGRHNGVGR REGSREARM PSKELWMRRL RILRRLLRKY RADKKIDRHV YRDLYMRAKG NVFRNKRNLV EHIHKIKNEK KKERQLAEQL A AKHLRDEQ ...String:
MVSLKLQARL ASSILGCGRA RVWLDPNEAV EIQNANSRKS VRKLIKDGFI IRKPVKVHSR ARWRKMKEAK DMGRHNGVGR REGSREARM PSKELWMRRL RILRRLLRKY RADKKIDRHV YRDLYMRAKG NVFRNKRNLV EHIHKIKNEK KKERQLAEQL A AKHLRDEQ NRNKARKQEL KKREKERERA RRDDAAAAAQ KKKADAAKKS AAPAAKSAAP AAKAAAPATK AAAPATKAAA AA PATKGAA PVKKSKK

UniProtKB: Putative 60S ribosomal protein L19

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Macromolecule #25: 60S ribosomal protein L18a

MacromoleculeName: 60S ribosomal protein L18a / type: protein_or_peptide / ID: 25 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 20.852338 KDa
SequenceString:
MVKPHLRHYQ VVGRESPSEK NPEPTVYKFE VFAPNFVVAK SRFWRMMRVK NKVKATHGDV LSCKVVKDAK LVARNYLVDI AYYSQRCGY TRMVKEFRDV SKTGAVSQAY HDLASRHRAR YHNIEVLNVK SIPDHEVKHL SIAQYHAPNL SFPLLQRRTK A TRKDRAIF VKKNTKRAVV A

UniProtKB: 60S ribosomal protein L18a

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Macromolecule #28: 40S ribosomal protein S3a

MacromoleculeName: 40S ribosomal protein S3a / type: protein_or_peptide / ID: 28 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 30.062037 KDa
SequenceString: MALGKNKRIS KGGKRGKRGK AQETMARKEW YDVVAPANFE KRQFAKTICN KTQGTRIAAD VLRGRVFEAN LADLNQSAGE EEAYRKVRF TVQEVQGRNL LTQFHSMEVT TDKMASLLRK WCTTMETTVE VKTADGYTMR LFVVAFTKPQ ANQQSRNCYA K QRLVKWLR ...String:
MALGKNKRIS KGGKRGKRGK AQETMARKEW YDVVAPANFE KRQFAKTICN KTQGTRIAAD VLRGRVFEAN LADLNQSAGE EEAYRKVRF TVQEVQGRNL LTQFHSMEVT TDKMASLLRK WCTTMETTVE VKTADGYTMR LFVVAFTKPQ ANQQSRNCYA K QRLVKWLR MRITKMIKRR LSKVQIKEAV SLLTRNVLSD ALVRRCNPIL PLRELRIRKV RVVRTPKFDA QALLSAHGTI PA SVEADQR EVEEAVEAAP AAEKAAE

UniProtKB: Small ribosomal subunit protein eS1

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Macromolecule #29: 40S ribosomal protein SA

MacromoleculeName: 40S ribosomal protein SA / type: protein_or_peptide / ID: 29 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 27.536629 KDa
SequenceString: MSAVESGSKV LRMKESDAQK LLAMRCHIGT RNQSSAMKKY IYGRTAEGSH IIDVHMMWEK LILAARVIAA VENPKDVCVC SSRLYGTRA IYKFSQHVGT SFHGGRFIPG TFTNQIQKKF VQPRVLVVTD PRTDHQAIRE ASLVNIPVIA LCDTDAPLEY V DIAIPCNN ...String:
MSAVESGSKV LRMKESDAQK LLAMRCHIGT RNQSSAMKKY IYGRTAEGSH IIDVHMMWEK LILAARVIAA VENPKDVCVC SSRLYGTRA IYKFSQHVGT SFHGGRFIPG TFTNQIQKKF VQPRVLVVTD PRTDHQAIRE ASLVNIPVIA LCDTDAPLEY V DIAIPCNN RGIKSIGMMY WLLAREVLRL RGTIVRSVPW EEKVDLFFYR DPNEAAEEKA AAAAAAPAAE AEEGFGWVER ND DNAWEA

UniProtKB: Small ribosomal subunit protein uS2

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Macromolecule #30: Putative 40S ribosomal protein S3

MacromoleculeName: Putative 40S ribosomal protein S3 / type: protein_or_peptide / ID: 30 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 24.511762 KDa
SequenceString: MGPLSKKRMI IRDGVFYAEL FEFLKRELAE EGFSGVSYHV TTLRTEIVIK ATKTREVLGV NGRRIRELTA CIQQRFNYKE GKLQLYVER VEVRGLSAMA QVESLRFKLL SNLQVRRAAM GIIRYVMESG AKGCEVTVGG KIKGQRAKSM TFRDGYMIKS G TAHKSFVD ...String:
MGPLSKKRMI IRDGVFYAEL FEFLKRELAE EGFSGVSYHV TTLRTEIVIK ATKTREVLGV NGRRIRELTA CIQQRFNYKE GKLQLYVER VEVRGLSAMA QVESLRFKLL SNLQVRRAAM GIIRYVMESG AKGCEVTVGG KIKGQRAKSM TFRDGYMIKS G TAHKSFVD SACRHCYMRA GCIGVKVKIM LPGDSTGRNG PSEPLPDVIT VIEPKQITAS E

UniProtKB: 40S ribosomal protein S3

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Macromolecule #31: Putative 40S ribosomal protein S9

MacromoleculeName: Putative 40S ribosomal protein S9 / type: protein_or_peptide / ID: 31 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 22.188902 KDa
SequenceString:
MRNYNNFNRV WKAPRRPFEK ERLDREMKLC GQYGLRCKRE IWRVNMTLSK MRRTARLLLT LPENHPRRLL EGSAIMRRCH EYGFLDEEK DKLDYVLSLT VPDILERRLQ TIVFKAGLAK SVHHARVLIQ QRHIAVAKQI VTIPSFIVRV SSERHIAFAD A SPFGNGRT GRVKRVRAKA AKRHAGGGDD DE

UniProtKB: Putative 40S ribosomal protein S9

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Macromolecule #32: 40S ribosomal protein S4

MacromoleculeName: 40S ribosomal protein S4 / type: protein_or_peptide / ID: 32 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 30.742084 KDa
SequenceString: MAKKHLKRLY APKDWMLSKL TGVFAPRPRP GPHKLRECLP LLVIIRNRLK YALNAREGEM ILRQGLVHVD NHPRRDGKYP AGFMDVVEI PKTGDRFRLM YDVKGRFALV NLSEAEAQIK LMKVVNLYTA TGRVPVAVTH DGHRIRYPDP HTSIGDTIVY N VKEKKCVD ...String:
MAKKHLKRLY APKDWMLSKL TGVFAPRPRP GPHKLRECLP LLVIIRNRLK YALNAREGEM ILRQGLVHVD NHPRRDGKYP AGFMDVVEI PKTGDRFRLM YDVKGRFALV NLSEAEAQIK LMKVVNLYTA TGRVPVAVTH DGHRIRYPDP HTSIGDTIVY N VKEKKCVD LIKNRQGKAV IVTGGANRGR IGEIVKVECH PGAFNIAHLK DASGAEFATR AANIFVIGKD LNNLQVTVPK QQ GLRMNVI QEREERLIAA EARKNAPARG ARRARK

UniProtKB: 40S ribosomal protein S4

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Macromolecule #33: 40S ribosomal protein S2

MacromoleculeName: 40S ribosomal protein S2 / type: protein_or_peptide / ID: 33 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 28.791135 KDa
SequenceString: MADTQPAQEA PATDAPRAER NFGRGRGGRG GRGRGRGGPG EEKEWVPCTK LGRLVKAQKV TSLEEIFLFS MPIKEHQIVD TLIAEGQLH DEMMKIYPVQ KATSAGQRTR FKAFNVVGDC DGHIGIGARV GKEVSLAIRA SMIAAKLNIV PVRRGYWGNK I GEPHTIPM ...String:
MADTQPAQEA PATDAPRAER NFGRGRGGRG GRGRGRGGPG EEKEWVPCTK LGRLVKAQKV TSLEEIFLFS MPIKEHQIVD TLIAEGQLH DEMMKIYPVQ KATSAGQRTR FKAFNVVGDC DGHIGIGARV GKEVSLAIRA SMIAAKLNIV PVRRGYWGNK I GEPHTIPM KVTGKCGSVA VRLVPAPRGT GIVAAPVPKK ILEFAGVEDV YTSSRGKTRT HGNLIMATFY ALRKTYGFLT PD LWADTEP SRDPTDEHAE LLAEMTTA

UniProtKB: 40S ribosomal protein S2

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Macromolecule #34: 40S ribosomal protein S6

MacromoleculeName: 40S ribosomal protein S6 / type: protein_or_peptide / ID: 34 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 28.370227 KDa
SequenceString: MKLNIAYPRN GTVKQFEISD EVLRRVQLQD YRLGNEVDGA IFGSEFKGYI FRLRGGSDKD GFPMVPGVLA SSRVSLLVKR GAIGFNTFR GYQGERRRKN VRGCVLASDI ALVNVTISKV GDQPIEGVTD TTAPRRLGPK RASKIRKLFN LSRTEDVRKY V VRRRVVKS ...String:
MKLNIAYPRN GTVKQFEISD EVLRRVQLQD YRLGNEVDGA IFGSEFKGYI FRLRGGSDKD GFPMVPGVLA SSRVSLLVKR GAIGFNTFR GYQGERRRKN VRGCVLASDI ALVNVTISKV GDQPIEGVTD TTAPRRLGPK RASKIRKLFN LSRTEDVRKY V VRRRVVKS GKKDRLKAPK IQRLITPRVK ARRAKKAKDA IAKVRASAAE RREYLRLIAS NRRALRQRDH SKKHTRKVHA QR AEVAAFQ KK

UniProtKB: Small ribosomal subunit protein eS6

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Macromolecule #35: 40S ribosomal protein S5

MacromoleculeName: 40S ribosomal protein S5 / type: protein_or_peptide / ID: 35 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 21.336623 KDa
SequenceString:
MSSKTPKLFN KWSFEGLETS ELALRDHIST TAAYVPHTSG RWQKRRFYKA RMPIVERLAN GLMFKGRGNG RKLQAARLLK HTLEIIHLL TDENPLQVVV DAVSKGAPRE DSTRVGSGGV VRRQAVDVSP MRRVNEAIYQ MCKGAREAAF RNLKSMPECL A DEIVNASK GSSNSYAIKK KDEVERVAKA NR

UniProtKB: 40S ribosomal protein S5

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Macromolecule #36: 40S ribosomal protein S7

MacromoleculeName: 40S ribosomal protein S7 / type: protein_or_peptide / ID: 36 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 23.765207 KDa
SequenceString: MQPHLRKLRK LKRGKPSDLE ESVAKALFEL EASHKTLRQE LPRFHVNTVR EVKVPRSKKT VLVVFYPLRF LMLVRKVQRA LTSELEKRH PGCLVMLVAQ RQITKRPTDV YKLQKVQRSK TSTAVFENIL NDMIYPSDVV GRRWRCRTDG SKLMKVFLDA R DRKRIESR ...String:
MQPHLRKLRK LKRGKPSDLE ESVAKALFEL EASHKTLRQE LPRFHVNTVR EVKVPRSKKT VLVVFYPLRF LMLVRKVQRA LTSELEKRH PGCLVMLVAQ RQITKRPTDV YKLQKVQRSK TSTAVFENIL NDMIYPSDVV GRRWRCRTDG SKLMKVFLDA R DRKRIESR LRAVAYVYKQ LTHRRVSFGF MWNPKLQQVS TR

UniProtKB: 40S ribosomal protein S7

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Macromolecule #37: 40S ribosomal protein S8

MacromoleculeName: 40S ribosomal protein S8 / type: protein_or_peptide / ID: 37 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 24.98425 KDa
SequenceString: MGIVRSRLHK RKITGGKTKI HRKRMKAELG RLPANTRLGA RRVSPVRARG GNFKIRALRL DTGNFAWASE AIAHRVRLLD VVYNATSNE LVRTKTLVKN CIVAVDAAPF KRWYAKHYGI DLDADKKSTK AAVAAEKKGR KSAHAAADKY DVNKASPKLQ R EWTRRRRN ...String:
MGIVRSRLHK RKITGGKTKI HRKRMKAELG RLPANTRLGA RRVSPVRARG GNFKIRALRL DTGNFAWASE AIAHRVRLLD VVYNATSNE LVRTKTLVKN CIVAVDAAPF KRWYAKHYGI DLDADKKSTK AAVAAEKKGR KSAHAAADKY DVNKASPKLQ R EWTRRRRN HRVEKAIADQ LREGRVLARI TSRPGQSGRA DGILLEGAEL QFYLKRLEKK KK

UniProtKB: Small ribosomal subunit protein eS8

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Macromolecule #38: Putative 40S ribosomal protein S16

MacromoleculeName: Putative 40S ribosomal protein S16 / type: protein_or_peptide / ID: 38 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 16.718586 KDa
SequenceString:
MPADKSYALK QVQTFGKKKT AIAVATVTKA AQCNIKVNGV PLQQILPDTL RAKIMEAITV VGSKYYSRLR IDVAVHGGGQ VSQAYAARQ AIAKGLIAFF QKYHNEVEKA ALKDKFLAYD KFLLIADPRR CEPKKWGRHS ARTRFTKSYR

UniProtKB: Ribosomal protein S16

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Macromolecule #39: Putative ribosomal protein S20

MacromoleculeName: Putative ribosomal protein S20 / type: protein_or_peptide / ID: 39 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 13.031983 KDa
SequenceString:
MDYPKKNQAA PAEGQTVRLT ITSRNAKAVE SVTSQLLTRA RDEKVTIHGP VRLPTRTLKI TTRKTPCGNG TNTWDTFELK IYKRIIDLH APTEQVKKIT SFTMESGVDV SITILDR

UniProtKB: Putative ribosomal protein S20

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Macromolecule #40: Putative 40S ribosomal protein S10

MacromoleculeName: Putative 40S ribosomal protein S10 / type: protein_or_peptide / ID: 40 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 18.681125 KDa
SequenceString:
MSTYVPKPSR DNVYRFFFTE GVIACKKDRM GTWTGTLGGN TFTVPCIQVM QLMRSLKSRN LIKEQYAWRH YYWTLNDEGI AYMRSYLHL APSAMPNTQK PSSVNFEKVT EGRGRGRGRG GRGRGEGRGR GRGEGRGRGR GRGFGGERMN YRAAAATSDG E AAPAPAAE

UniProtKB: Putative 40S ribosomal protein S10

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Macromolecule #41: 40S ribosomal protein S14

MacromoleculeName: 40S ribosomal protein S14 / type: protein_or_peptide / ID: 41 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 15.62318 KDa
SequenceString:
MSKKQEVKAY GPNVKKGDLV YGVVHIFASF NDTFVHVTDM SGRETYVKVT GGMKVKADRD ESSPYAAMMA AQDVVARCKE CGINALHVK MRAVGGVRTK SPGPGAQAAL RALARAGMKI GRIEDVTPIP TDSTRRKGSR RGRRL

UniProtKB: 40S ribosomal protein S14

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Macromolecule #42: Putative 40S ribosomal protein S23

MacromoleculeName: Putative 40S ribosomal protein S23 / type: protein_or_peptide / ID: 42 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 15.969643 KDa
SequenceString:
MTKTNGQNAA RKLVRLRCRN RWADKGWKRA HTFSARKANP FGGSSHAKGI VLEKIGVGAK QPNSAIRKCV RVQLIKNDKK IIAFVPNDG CLHFIEENDE VLVSGFGRSG HAVGDIPGVR FKIVKVSNVG LYALYRQKKE KPRN

UniProtKB: Putative 40S ribosomal protein S23

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Macromolecule #43: 40S ribosomal protein S12

MacromoleculeName: 40S ribosomal protein S12 / type: protein_or_peptide / ID: 43 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 15.627837 KDa
SequenceString:
MAEETVRVEV PAVEENVVVD VAPESLEDAV RIVIQKSLEA NGLVRGLSEV ARTLDCKTAH MCILADDCED EEYKKLVTAL AKQGNIDLI NVEEREKLAQ WAGLVRRDVA GEVTKTLKCS SVAIRDFGER TKALDYLLSQ LH

UniProtKB: 40S ribosomal protein S12

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Macromolecule #44: Putative 40S ribosomal protein S18

MacromoleculeName: Putative 40S ribosomal protein S18 / type: protein_or_peptide / ID: 44 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 17.433422 KDa
SequenceString:
MSLTLIPDHF QHIVRLLNTN VEGKRKVPFA LRMVKGVGIR FAYLVCKKAG IDVERRAGTL TAEELEKIAE IIADPAKFKI PDWFLNRQR DPKTGKTEHL SSSMVDTRLR DDLERLKKMR AHRGVRHAYG LRVRGQHTCT SGRHGKTVGV SRGK

UniProtKB: Ribosomal protein S18

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Macromolecule #45: Putative ribosomal protein S29

MacromoleculeName: Putative ribosomal protein S29 / type: protein_or_peptide / ID: 45 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 6.696929 KDa
SequenceString:
MGHLDQWRSR QKIGMGKGAR CCVICSNQKA LIRKYELNVC RQCFRENAEH IGFTKLR

UniProtKB: Putative ribosomal protein S29

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Macromolecule #46: Putative 40S ribosomal protein S13

MacromoleculeName: Putative 40S ribosomal protein S13 / type: protein_or_peptide / ID: 46 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 17.482764 KDa
SequenceString:
MVRMHGNGRG KASSALPYRR TPPAWLKIAS RNVVKMVCKS SRKGMMPSQI GMELRDSMGI AQVKNVTGRK ILRILKHNGL APEIPEDLY FLVKRATQMR KHLERHTTDR DTKYRLILVE SRIHRLARYY KRVKQLPPTW KYESSTASAM VA

UniProtKB: Putative 40S ribosomal protein S13

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Macromolecule #47: Putative 40S ribosomal protein S11

MacromoleculeName: Putative 40S ribosomal protein S11 / type: protein_or_peptide / ID: 47 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 20.023457 KDa
SequenceString:
MPVAPQYYHA HAVDATIQHE KAYQRQTAVN ENMHRPSRKH VNKSGHIRYS KKIGLGFKTP AKALNGKYID RKCPFTSNVV IRGRILRGV VHSTKMHRTI IIRRNYLHFI KKYQRYQKRH KSLAVHCSPA FDPKQGDEVV IGQCRPLSKT IRYNVLEVVS K SSADKMGK KFAKN

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Macromolecule #48: Putative 40S ribosomal protein S17

MacromoleculeName: Putative 40S ribosomal protein S17 / type: protein_or_peptide / ID: 48 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 16.551529 KDa
SequenceString:
MGKIRTKTVK RASRQVVEKY YSKLNFDFYQ NKRVIMDVTI AESKKLKNKI AGYTTHIMKR LARGPVRGIS LKLQEEERER RMDHAPATS DVDKVIQSGV SVDKKTMQML QRLEIGVPRR VKRADAAVTK VKAAPRRRQQ KSSK

UniProtKB: Putative 40S ribosomal protein S17

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Macromolecule #49: Putative 40S ribosomal protein S15

MacromoleculeName: Putative 40S ribosomal protein S15 / type: protein_or_peptide / ID: 49 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 17.472395 KDa
SequenceString:
MASNITAERY EQLKKERTFH KFTYRGLEID PLLALSEEEF KALVHARARR NMNRHADRRP PVLLKRLREA KKHVKVGEKP KAVKTHLRD VVITPEMVGS VVAIYNGHQF NAVEIKGEMI GHYLGEFSMS YRPVLHGRPG VGATHSSRFI PIK

UniProtKB: Putative 40S ribosomal protein S15

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Macromolecule #50: 40S ribosomal protein S19-like protein

MacromoleculeName: 40S ribosomal protein S19-like protein / type: protein_or_peptide / ID: 50 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 18.158078 KDa
SequenceString:
MTAPRNKIHR IGKRKGATLK DVSAWRWIKT AARHFKQEGK IFVPNCTEIM KSSHGRERAP QNPDWYYIRC AAVLRAIYLR PGVGYGGLS KRFGNKKNYG SRPEHTVTSS TGPLHWACKS LTKLGLVEPG AQSGQRLTRK GHKFADSLAF QVQIRKFGQS K A

UniProtKB: 40S ribosomal protein S19-like protein

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Macromolecule #51: Putative 40S ribosomal protein S21

MacromoleculeName: Putative 40S ribosomal protein S21 / type: protein_or_peptide / ID: 51 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 17.035592 KDa
SequenceString:
MATIGMFNEE GENVDLYIPR KCHATTTLIE AHDHAAVQIS IANVGPNGVI NGTTTTLCIA GYLRSQGESD HAINHITIDR GIMRIKTGK PKRASKSKSK KPAAKGAAAG AAAQKGARPP AQKGARPPAQ KGARPPAQKG ARPPAQKGAR PPAQKGAAPA R KNRA

UniProtKB: Putative 40S ribosomal protein S21

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Macromolecule #52: 40S ribosomal protein S24

MacromoleculeName: 40S ribosomal protein S24 / type: protein_or_peptide / ID: 52 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 15.808882 KDa
SequenceString:
MVFQKKKAEV CIRTSQFKVN KLLNRKQFIV EVNHPHWCGT VPTQLIRKKL ATLYKVPDAS QVSLFGFKTK FGGGKTTGFG LIYDDLASL KRFEPNYRKT RMGFGKARLP ARKSVKERRN RNKKLRGKAK GKQVAKKK

UniProtKB: 40S ribosomal protein S24

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Macromolecule #53: Putative 60S ribosomal protein L21

MacromoleculeName: Putative 60S ribosomal protein L21 / type: protein_or_peptide / ID: 53 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 18.068223 KDa
SequenceString:
MVHSYGYKSG TRHLFAKKFR KHGVPSVSTI LTNIKVGDYV DVVADSAVRE GMPHKYYHGR TGIVWNVTPR GVGVIINKPV RTRTLRKRI CVRFEHVRKS RCQEAFKAKE HQFQAYLAAK KAGKALPPLQ KSSRLGGIVR PKNVEVLARR VADYEAMVPY

UniProtKB: Putative 60S ribosomal protein L21

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Macromolecule #54: 40S ribosomal protein S25

MacromoleculeName: 40S ribosomal protein S25 / type: protein_or_peptide / ID: 54 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 13.071399 KDa
SequenceString:
MPPKAGQTKK AKMEAANKGA KKTTKKWSKG QSREALQNAV MFDKETYDKL RSEVPKYKLI TPSIISDRLK IAVSIAAAGL KQLCREKLI RLVSCSSKTR VYTRIVQAAP AEAAAAAPAA E

UniProtKB: 40S ribosomal protein S25

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Macromolecule #55: Putative 40S ribosomal protein S27-1

MacromoleculeName: Putative 40S ribosomal protein S27-1 / type: protein_or_peptide / ID: 55 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 9.819463 KDa
SequenceString:
MGFFDADLSY PTVRTERMKH KRRRLVQGPN SYFMDVSCPR CRQVTVVYSH ATTSVECKGC SKKLCRPTGG KALLVEGCGY RRKPDH

UniProtKB: Putative 40S ribosomal protein S27-1

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Macromolecule #56: 40S ribosomal protein S26

MacromoleculeName: 40S ribosomal protein S26 / type: protein_or_peptide / ID: 56 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 12.794251 KDa
SequenceString:
MTTKRRNHGR SKPAHSRGRV KPIHCFNCGR LTPKDKAVGR FVVRRMLDAA SARDVAEASP VYGANFPMPR LYMKQRFCIA CAIHSRTVR ARPVGNRKIR YTKKVPFRPA GKK

UniProtKB: 40S ribosomal protein S26

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Macromolecule #57: Putative 40S ribosomal protein S33

MacromoleculeName: Putative 40S ribosomal protein S33 / type: protein_or_peptide / ID: 57 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 9.763191 KDa
SequenceString:
MADSKKDNKK TEEVVTQGTD QAQVGLIIKV LGRTGSRGNV TQVRVRLMAE AGSPDYNRTI VRNVKGPCKE NDMLSLMETE REARRLR

UniProtKB: Putative 40S ribosomal protein S33

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Macromolecule #58: 40S ribosomal protein S30

MacromoleculeName: 40S ribosomal protein S30 / type: protein_or_peptide / ID: 58 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 7.394894 KDa
SequenceString:
MGKIHGSLAR AGKVKNQTPK VAKQEKPKQP RGRALKRLKY TRRFLSKTVK PGEKVHMNKQ PPGKAG

UniProtKB: 40S ribosomal protein S30

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Macromolecule #59: Guanine nucleotide-binding protein subunit beta-like protein

MacromoleculeName: Guanine nucleotide-binding protein subunit beta-like protein
type: protein_or_peptide / ID: 59 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 34.441516 KDa
SequenceString: MNYEGHLKGH RGWVTSLACP QQAGSYIKVV STSRDGTAIS WKANPDRHSV DSDYGLPNHR LEGHTGFVSC VSLAHATDYA LTASWDRSI RMWDLRNGQC QRKFLKHTKD VLAVAFSPDD RLIVSAGRDN VIRVWNVAGE CMHEFLRDGH EDWVSSICFS P SLEHPIVV ...String:
MNYEGHLKGH RGWVTSLACP QQAGSYIKVV STSRDGTAIS WKANPDRHSV DSDYGLPNHR LEGHTGFVSC VSLAHATDYA LTASWDRSI RMWDLRNGQC QRKFLKHTKD VLAVAFSPDD RLIVSAGRDN VIRVWNVAGE CMHEFLRDGH EDWVSSICFS P SLEHPIVV SGSWDNTIKV WNVNGGKCER TLKGHSNYVS TVTVSPDGSL CASGGKDGAA LLWDLSTGEQ LFKINVESPI NQ IAFSPNR FWMCVATERS LSVYDLESKA VIAELTPDGA KPSECISIAW SADGNTLYSG HKDNLIRVWS ISDAE

UniProtKB: Activated protein kinase c receptor

+
Macromolecule #60: Putative RNA binding protein

MacromoleculeName: Putative RNA binding protein / type: protein_or_peptide / ID: 60 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 25.229275 KDa
SequenceString: MPAKAAAKPV KPAAKAAPKP ANKAPAPKAA AAKPVAKAAP KAAAPAARPA SGSSNGVYVK NWGTGSVADA ANVFSAAGKV VKVQLRRQR YAIVFFENSA AVKKAIDLFN EKEVLGKTVL VVPAKTSPKP DAHENSSCVF VSPIFRPSTT KAQVMELFAG V KVQRLRMY ...String:
MPAKAAAKPV KPAAKAAPKP ANKAPAPKAA AAKPVAKAAP KAAAPAARPA SGSSNGVYVK NWGTGSVADA ANVFSAAGKV VKVQLRRQR YAIVFFENSA AVKKAIDLFN EKEVLGKTVL VVPAKTSPKP DAHENSSCVF VSPIFRPSTT KAQVMELFAG V KVQRLRMY RQNFAYAYLD SPAAAKKFVE EKNGTEFRGH TLRVALSARS LEKLRARQEA ANVVIAAHRH YKTHERQ

UniProtKB: Putative RNA binding protein

+
Macromolecule #61: Putative 40S ribosomal protein S15A

MacromoleculeName: Putative 40S ribosomal protein S15A / type: protein_or_peptide / ID: 61 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 14.719258 KDa
SequenceString:
MTMMSVLANA LRTIASAERR GKRQVLIRPS SKVVVKFLQV MQKHGYIGEF EIIDDHRAGK IVVNLNGRLN KCGAICPRFD CATTDYEKW MKNILPSRQF GFVVLTTSLG IMDHEEARSR NTGGKVLGFF Y

UniProtKB: Putative 40S ribosomal protein S15A

+
Macromolecule #62: Putative 60S ribosomal protein L17

MacromoleculeName: Putative 60S ribosomal protein L17 / type: protein_or_peptide / ID: 62 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 19.124547 KDa
SequenceString:
MTHYSRKPQV SSKSAKAKVS DLRCHYKNTF ETANVINGMP LRKAQQLYRQ VLAKTRCIPF KRYNGKIGRT AQAKEWGQTK GRWPRKSVV AMMSLLKNAE ANAIEKGLDP NQMVIKHVQV DQAARMRRRT YRAHGRITPY MCSPCHVQLF MSEKKERVPA P KSAPKK

UniProtKB: Putative 60S ribosomal protein L17

+
Macromolecule #63: Putative 60S ribosomal protein L22

MacromoleculeName: Putative 60S ribosomal protein L22 / type: protein_or_peptide / ID: 63 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 15.030535 KDa
SequenceString:
MVAVRAKVGS RSYVRQKQLA KGKKVFKIDC SIPAADGIFS EDVLGNFEQF FQDNTKLNGR KGKLSDKVRL SMNDNVLTIS TTMAYRKKY FKYLTKKFLK KKDLRDWIRI LATGKGTYQL KYFNIQDQEE

UniProtKB: Large ribosomal subunit protein eL22

+
Macromolecule #64: Putative 60S ribosomal protein L23a

MacromoleculeName: Putative 60S ribosomal protein L23a / type: protein_or_peptide / ID: 64 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 16.372358 KDa
SequenceString:
MPPAQKTAKK AAPKDAKATK VVKVTTRKSY TRPQFRRPHT YRKPAMAKPS NRVTVESKDI AAFNVIRYPL TTDKAMKKIE ENNTLTFIV DSRANKTEIK KAMRKLYQVK AVKVNTLIRP DGLKKAYIRL SAAHDALDTA NKIGLV

UniProtKB: Putative 60S ribosomal protein L23a

+
Macromolecule #65: Putative 60S ribosomal protein L26

MacromoleculeName: Putative 60S ribosomal protein L26 / type: protein_or_peptide / ID: 65 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 16.21715 KDa
SequenceString:
MASIKCGSRR KARRAHFQAP SHVRRVLMSA PLSKELRAKY NVRAMPVRKD DEVIVKRGTF KGREGKVTAC YRLKWVILID KVNREKANG STVAVGIHPS NVEITKLKLT HHRKSILERK DRSSKSDKGK GKISAADKAM QQMD

UniProtKB: Putative 60S ribosomal protein L26

+
Macromolecule #66: Putative ribosomal protein L24

MacromoleculeName: Putative ribosomal protein L24 / type: protein_or_peptide / ID: 66 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 14.608168 KDa
SequenceString:
MRTIECEFSH FAVHPGHGRR YVPFAFLSTK PVLTFSRPKC FALYMRKKNP RFIPWTRTYR RIHRKTTTDR VNRRRAARAV RVQRAIVGA DLSYIQEVRA ARKEDRSAKA KAVRAEVAER KAAKK

UniProtKB: Putative ribosomal protein L24

+
Macromolecule #67: 60S ribosomal protein L27

MacromoleculeName: 60S ribosomal protein L27 / type: protein_or_peptide / ID: 67 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 15.46933 KDa
SequenceString:
MTKFLKPGKV VIVTAGRYAG HKAVIVQNSD VVTKERPYGR ALLAGIKKYP KKVVRGMSKQ TIARRSQVGV FLRVVNHKHF LPTRYNVDM SKELRGKINV SDASKRSRSK RLVRHVFQAR YNAGSSMWFF QRLRF

UniProtKB: Putative ribosomal protein L27

+
Macromolecule #68: Putative 60S ribosomal protein L28

MacromoleculeName: Putative 60S ribosomal protein L28 / type: protein_or_peptide / ID: 68 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 16.314906 KDa
SequenceString:
MSHSVDLQWV LVRQNSRFLQ KRGGIRMSND PFNNNGNWTK RHCGFLNEKA AVVKPAKGGA ICVTVKDGSS NNKPRQTYKK TVHAAGVRA SDVSRAVAAV RPDLADVSFR RARRMACIAS RTAKVAAARK ARSEKIKFSR KSARAKRN

UniProtKB: Large ribosomal subunit protein eL28

+
Macromolecule #69: Putative 60S ribosomal protein L35

MacromoleculeName: Putative 60S ribosomal protein L35 / type: protein_or_peptide / ID: 69 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 15.262208 KDa
SequenceString:
MSHHMKIKDL REKSKDDLLK TLTEYKKELS QLRVVQQTGG AETRLGRIRP IRKSIARILT VLNQNERSNL KMFYADRKLR CKTPKVLRT KLTHRRRLAL KENEKNRKTS RQMRQAHKFP KRVYAVKI

UniProtKB: Putative 60S ribosomal protein L35

+
Macromolecule #70: 60S ribosomal protein L29

MacromoleculeName: 60S ribosomal protein L29 / type: protein_or_peptide / ID: 70 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 8.001308 KDa
SequenceString:
MAKSKNHTNH NQSSKNHRNG IKGPVPLHLH NSKRGSWLPA LVNARRVRKH NQKAALKKRR ERIAAFAAKN

UniProtKB: 60S ribosomal protein L29

+
Macromolecule #71: Putative 60S ribosomal protein L7

MacromoleculeName: Putative 60S ribosomal protein L7 / type: protein_or_peptide / ID: 71 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 28.900037 KDa
SequenceString: MATHSVYGNA SDMPAVPAPE SAIKRAAFKQ QQTESFKKAV VARKAAKAAL KKTAYLRARK YSREYRGAEK KLVTLRRQAA SHGNYYLEA KPKVAVVTRI RGIAKVNPKQ RKILQLLRLR QIFNTVFVKM NKPMENMLRA VEPYIAYGYP SLATVRAMVY K RGYLKING ...String:
MATHSVYGNA SDMPAVPAPE SAIKRAAFKQ QQTESFKKAV VARKAAKAAL KKTAYLRARK YSREYRGAEK KLVTLRRQAA SHGNYYLEA KPKVAVVTRI RGIAKVNPKQ RKILQLLRLR QIFNTVFVKM NKPMENMLRA VEPYIAYGYP SLATVRAMVY K RGYLKING QRVKITDNQM IKDKYNNVDI VCAEDMVNQI YTCGKHFRTV THGMWPFKLA PPAGGMRQKR RHFVEGGDYG NR DTLINRF LARMI

UniProtKB: Putative 60S ribosomal protein L7

+
Macromolecule #72: 60S ribosomal protein L30

MacromoleculeName: 60S ribosomal protein L30 / type: protein_or_peptide / ID: 72 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 11.370224 KDa
SequenceString:
MAKKTKSKVD TINAKLQLVM KSGKYVLGTQ QALTTLRQGR SKLVVIANNC PPIRRAEVEY YCTLSKTPIH HYSGNNLDLG TACGKHFRT CVLSVTNVGD SDIAA

UniProtKB: 60S ribosomal protein L30

+
Macromolecule #73: Putative 60S ribosomal subunit protein L31

MacromoleculeName: Putative 60S ribosomal subunit protein L31 / type: protein_or_peptide / ID: 73 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 21.316254 KDa
SequenceString:
MTRAGMKGKV LGKEKKAAII DARKKAAESR KNRDDKRWKR VLANMDEEKR KKFHGVGNTA KNSRVRGATR ASLLKRTGRK PDAVSMEAT IHLSKLLKKK TFSKRAPLAI KRIKAFVGRL MKTKDNRIDA SLNTYIWHKG VKGVPGRVRV LIQRKSETTE G NKHKHFYT VISNVPVASF KGLTTKTVEQ

UniProtKB: Putative 60S ribosomal subunit protein L31

+
Macromolecule #74: 60S ribosomal protein L32

MacromoleculeName: 60S ribosomal protein L32 / type: protein_or_peptide / ID: 74 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 15.458153 KDa
SequenceString:
MVKPTVSKAI VKKRTKRFTR HRYELFPQLS SSWRKPRGED SPVRRRYKGQ KAMPNKGYGS DRATKYITPS GFRNFPINNV EDLYMLVMQ NRKYAGVISH TVGARKRKAI VRKAMELDVR LANGNAKLRK IANQ

UniProtKB: 60S ribosomal protein L32

+
Macromolecule #75: Putative ribosomal protein l35a

MacromoleculeName: Putative ribosomal protein l35a / type: protein_or_peptide / ID: 75 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 16.492312 KDa
SequenceString:
MTTSKVHSQR SKKLHQLSAK TSRVNRNRKA PRLYMKGTLA GYTRGLHGQT KQTALVRVEN VNTREDATWY VGKRVCYVYH GKKVKRCVR WSKAPARRST TRALWGRVTR PHGNAGMMRV KFNGASVPAS AIGRRIRVYL YPSQI

UniProtKB: Putative ribosomal protein l35a

+
Macromolecule #76: Putative 60S ribosomal protein L34

MacromoleculeName: Putative 60S ribosomal protein L34 / type: protein_or_peptide / ID: 76 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 19.335119 KDa
SequenceString:
MSCPRVQYRR RMHYATRGNR MKMVRTPGNK LVMQKRAKRS QGIHTPWVLG HKRLGGTKAL RHIDARLASR HEKSVSRAYG GVLSHDQVR DRVVRAFLVE EQRIVKQALK EHSKMKLSHK RTANKKKSKQ SKKEAIAKKI STKTVSKKKV PAKKATTTRQ P VGSKLVKK

UniProtKB: Large ribosomal subunit protein eL34

+
Macromolecule #77: Putative 60S Ribosomal protein L36

MacromoleculeName: Putative 60S Ribosomal protein L36 / type: protein_or_peptide / ID: 77 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 11.9752 KDa
SequenceString:
MSAPTPRTGI IAGFNKGHVT TRRPRQPSPN DRFAVPHKHL RAVKAIIADL VGLSPLEKRV QEFLRVGKEK RALKYCKKRL GDFTAAKKK RSKMEEALRH ATKKHH

UniProtKB: Putative 60S Ribosomal protein L36

+
Macromolecule #78: Ribosomal protein L37

MacromoleculeName: Ribosomal protein L37 / type: protein_or_peptide / ID: 78 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 9.86259 KDa
SequenceString:
MTKGTTSMGQ RHGRTHILCR RCGRNSYHVQ WERCAACAYP RASRRRYNWS VKAIKRRRTG TGRCRYLKVV NRRIANHFKT PKA

UniProtKB: Ribosomal protein L37

+
Macromolecule #79: Putative ribosomal protein L38

MacromoleculeName: Putative ribosomal protein L38 / type: protein_or_peptide / ID: 79 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 9.479287 KDa
SequenceString:
MPREIKTLKE FLAICSRKDA RCVKVKHNPS ATKFKVRCSR YLYTLVVNDK KKADKIERSI HPSVKKIAVT ARSHAKTNAG SKQ

UniProtKB: Putative ribosomal protein L38

+
Macromolecule #80: Putative 60S ribosomal protein L39

MacromoleculeName: Putative 60S ribosomal protein L39 / type: protein_or_peptide / ID: 80 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 6.504845 KDa
SequenceString:
MGRFKPLAVK KKYAKKMNQN KPVPYWIRLR TGNRIKWNEK RRHWRRTKLN Y

UniProtKB: Putative 60S ribosomal protein L39

+
Macromolecule #81: Ubiquitin-60S ribosomal protein L40

MacromoleculeName: Ubiquitin-60S ribosomal protein L40 / type: protein_or_peptide / ID: 81 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 14.711425 KDa
SequenceString:
MQIFVKTLTG KTIALEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EEGRTLSDYN IQKESTLHLV LRLRGGVMEP TLVALAKKY NWEKKVCRRC YARLPVRATN CRKKACGHCS NLRMKKKLR

UniProtKB: Ubiquitin-ribosomal protein eL40 fusion protein

+
Macromolecule #82: 60S ribosomal protein L41

MacromoleculeName: 60S ribosomal protein L41 / type: protein_or_peptide / ID: 82 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 4.390496 KDa
SequenceString:
MGTVSRPRGM RPKWHKKRIK RLKLRRRRMR QRSK

+
Macromolecule #83: 60S ribosomal protein L37a

MacromoleculeName: 60S ribosomal protein L37a / type: protein_or_peptide / ID: 83 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 10.337223 KDa
SequenceString:
MAKRTVKMGV MGRYGTRYGA NPRKRAKKLE VSQHAKHFCS FCGKFAFRRK AVGIWRCDGC SKTVAGGAYT LSTPNNSTVR STVRRLREL AKI

UniProtKB: 60S ribosomal protein L37a

+
Macromolecule #84: Putative 60S ribosomal protein L44

MacromoleculeName: Putative 60S ribosomal protein L44 / type: protein_or_peptide / ID: 84 / Number of copies: 1 / Enantiomer: LEVO
Source (natural)Organism: Leishmania major strain Friedlin (eukaryote)
Molecular weightTheoretical: 12.302685 KDa
SequenceString:
MVNYPKKKVM HCGDARCNAH KSFKVVQYKA GKARLFARGK RRYDRKQSGY GGQTKPVFHK KAKTTKKIVL KLQCSGCKSI RQVVLKRTK HFELNDKKKT GNKDPTW

UniProtKB: Putative 60S ribosomal protein L44

+
Macromolecule #86: MAGNESIUM ION

MacromoleculeName: MAGNESIUM ION / type: ligand / ID: 86 / Number of copies: 302 / Formula: MG
Molecular weightTheoretical: 24.305 Da

+
Macromolecule #87: POTASSIUM ION

MacromoleculeName: POTASSIUM ION / type: ligand / ID: 87 / Number of copies: 43 / Formula: K
Molecular weightTheoretical: 39.098 Da

+
Macromolecule #88: SODIUM ION

MacromoleculeName: SODIUM ION / type: ligand / ID: 88 / Number of copies: 17
Molecular weightTheoretical: 22.99 Da

+
Macromolecule #89: ZINC ION

MacromoleculeName: ZINC ION / type: ligand / ID: 89 / Number of copies: 5 / Formula: ZN
Molecular weightTheoretical: 65.409 Da

+
Macromolecule #90: water

MacromoleculeName: water / type: ligand / ID: 90 / Number of copies: 49 / Formula: HOH
Molecular weightTheoretical: 18.015 Da
Chemical component information

ChemComp-HOH:
WATER

-
Experimental details

-
Structure determination

Methodcryo EM
Processingsingle particle reconstruction
Aggregation stateparticle

-
Sample preparation

BufferpH: 7.6
VitrificationCryogen name: ETHANE

-
Electron microscopy

MicroscopeFEI TITAN KRIOS
Image recordingFilm or detector model: GATAN K3 BIOQUANTUM (6k x 4k) / Average electron dose: 0.83 e/Å2
Electron beamAcceleration voltage: 300 kV / Electron source: FIELD EMISSION GUN
Electron opticsIllumination mode: FLOOD BEAM / Imaging mode: BRIGHT FIELD / Nominal defocus max: 1.3 µm / Nominal defocus min: 0.7000000000000001 µm
Experimental equipment
Model: Titan Krios / Image courtesy: FEI Company

-
Image processing

Startup modelType of model: EMDB MAP
EMDB ID:

15124

Final reconstructionResolution.type: BY AUTHOR / Resolution: 2.4 Å / Resolution method: FSC 0.143 CUT-OFF / Number images used: 212912
Initial angle assignmentType: MAXIMUM LIKELIHOOD
Final angle assignmentType: MAXIMUM LIKELIHOOD

+
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