+データを開く
-基本情報
登録情報 | データベース: SASBDB / ID: SASDFD2 |
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試料 | wild-type human Latent Transforming Growth Factor beta 1 (LTGFB-1)
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機能・相同性 | 機能・相同性情報 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains / regulation of interleukin-23 production / branch elongation involved in mammary gland duct branching / positive regulation of primary miRNA processing / regulation of branching involved in mammary gland duct morphogenesis / positive regulation of microglia differentiation / Influenza Virus Induced Apoptosis / negative regulation of skeletal muscle tissue development / frontal suture morphogenesis / regulation of enamel mineralization ...adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains / regulation of interleukin-23 production / branch elongation involved in mammary gland duct branching / positive regulation of primary miRNA processing / regulation of branching involved in mammary gland duct morphogenesis / positive regulation of microglia differentiation / Influenza Virus Induced Apoptosis / negative regulation of skeletal muscle tissue development / frontal suture morphogenesis / regulation of enamel mineralization / regulation of cartilage development / TGFBR2 MSI Frameshift Mutants in Cancer / regulatory T cell differentiation / regulation of blood vessel remodeling / tolerance induction to self antigen / regulation of striated muscle tissue development / regulation of protein import into nucleus / negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target / embryonic liver development / columnar/cuboidal epithelial cell maturation / negative regulation of hyaluronan biosynthetic process / type III transforming growth factor beta receptor binding / positive regulation of cardiac muscle cell differentiation / myofibroblast differentiation / Langerhans cell differentiation / positive regulation of odontogenesis / positive regulation of receptor signaling pathway via STAT / positive regulation of exit from mitosis / extracellular matrix assembly / connective tissue replacement involved in inflammatory response wound healing / odontoblast differentiation / TGFBR2 Kinase Domain Mutants in Cancer / negative regulation of macrophage cytokine production / positive regulation of smooth muscle cell differentiation / positive regulation of mesenchymal stem cell proliferation / positive regulation of isotype switching to IgA isotypes / SMAD2/3 Phosphorylation Motif Mutants in Cancer / TGFBR1 KD Mutants in Cancer / mammary gland branching involved in thelarche / TGFBR3 regulates TGF-beta signaling / retina vasculature development in camera-type eye / membrane protein intracellular domain proteolysis / response to laminar fluid shear stress / heart valve morphogenesis / positive regulation of vasculature development / bronchiole development / hyaluronan catabolic process / ATP biosynthetic process / positive regulation of extracellular matrix assembly / receptor catabolic process / lens fiber cell differentiation / positive regulation of branching involved in ureteric bud morphogenesis / negative regulation of extracellular matrix disassembly / TGFBR1 LBD Mutants in Cancer / type II transforming growth factor beta receptor binding / oligodendrocyte development / germ cell migration / negative regulation of biomineral tissue development / positive regulation of mononuclear cell migration / response to salt / type I transforming growth factor beta receptor binding / phospholipid homeostasis / positive regulation of chemotaxis / endoderm development / negative regulation of myoblast differentiation / positive regulation of vascular permeability / digestive tract development / positive regulation of endothelial cell apoptotic process / cell-cell junction organization / response to vitamin D / positive regulation of regulatory T cell differentiation / response to cholesterol / negative regulation of interleukin-17 production / surfactant homeostasis / deubiquitinase activator activity / negative regulation of ossification / negative regulation of release of sequestered calcium ion into cytosol / phosphate-containing compound metabolic process / positive regulation of fibroblast migration / positive regulation of chemokine (C-X-C motif) ligand 2 production / aortic valve morphogenesis / ventricular cardiac muscle tissue morphogenesis / ureteric bud development / sprouting angiogenesis / face morphogenesis / neural tube development / negative regulation of phagocytosis / RUNX3 regulates CDKN1A transcription / Molecules associated with elastic fibres / positive regulation of epidermal growth factor receptor signaling pathway / negative regulation of neuroblast proliferation / macrophage derived foam cell differentiation / lung alveolus development / Syndecan interactions / cellular response to insulin-like growth factor stimulus / muscle cell cellular homeostasis / negative regulation of cell-cell adhesion / negative regulation of fat cell differentiation / odontogenesis of dentin-containing tooth / T cell homeostasis 類似検索 - 分子機能 |
生物種 | Homo sapiens (ヒト) |
引用 | 日付: 2019 Jul 1 タイトル: Structural consequences of transforming growth factor beta-1 activation from near-therapeutic X-ray doses 著者: Stachowski T / Grant T |
登録者 |
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-構造の表示
-ダウンロードとリンク
-Data source
SASBDBのページ | SASDFD2 |
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-関連構造データ
関連構造データ | C: 同じ文献を引用 (文献) |
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類似構造データ | 類似検索 - 機能・相同性F&H 検索 |
-外部リンク
「今月の分子」の関連する項目 |
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-モデル
-試料
試料 | 名称: wild-type human Latent Transforming Growth Factor beta 1 (LTGFB-1) 試料濃度: 1 mg/ml |
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バッファ | 名称: phosphate buffered saline 2% glycerol / pH: 7.4 |
要素 #1478 | 名称: LTGFB-1 / タイプ: protein / 記述: Human Latent Transforming Growth Factor beta 1 / 分子量: 42.958 / 分子数: 2 / 由来: Homo sapiens / 参照: UniProt: P01137 配列: HHHHHHLEVL FQGPLSTSKT IDMELVKRKR IEAIRGQILS KLRLASPPSQ GEVPPGPLPE AVLALYNSTR DRVAGESAEP EPEPEADYYA KEVTRVLMVE THNEIYDKFK QSTHSIYMFF NTSELREAVP EPVLLSRAEL RLLRLKLKVE QHVELYQKYS NNSWRYLSNR ...配列: HHHHHHLEVL FQGPLSTSKT IDMELVKRKR IEAIRGQILS KLRLASPPSQ GEVPPGPLPE AVLALYNSTR DRVAGESAEP EPEPEADYYA KEVTRVLMVE THNEIYDKFK QSTHSIYMFF NTSELREAVP EPVLLSRAEL RLLRLKLKVE QHVELYQKYS NNSWRYLSNR LLAPSDSPEW LSFDVTGVVR QWLSRGGEIE GFRLSAHCSC DSRDNTLQVD INGFTTGRRG DLATIHGMNR PFLLLMATPL ERAQHLQSSR HRRALDTNYC FSSTEKNCCV RQLYIDFRKD LGWKWIHEPK GYHANFCLGP CPYIWSLDTQ YSKVLALYNQ HNPGASAAPC CVPQALEPLP IVYYVGRKPK VEQLSNMIVR SCKCS |
-実験情報
ビーム | 設備名称: Advanced Light Source (ALS) 12.3.1 (SIBYLS) / 地域: Berkeley, CA / 国: USA / 線源: X-ray synchrotron / 波長: 0.1127 Å / スペクトロメータ・検出器間距離: 2 mm | ||||||||||||||||||||||||||||||
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検出器 | 名称: Pilatus3 X 2M / Pixsize x: 172 mm | ||||||||||||||||||||||||||||||
スキャン | タイトル: wild-type human Latent Transforming Growth Factor beta 1 (LTGFB-1) 測定日: 2018年10月4日 / 保管温度: 4 °C / セル温度: 10 °C / 照射時間: 0.1 sec. / フレーム数: 49 / 単位: 1/A /
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距離分布関数 P(R) | ソフトウェア P(R): GNOM 5.0 / ポイント数: 703 /
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結果 | カーブのタイプ: single_conc /
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