登録情報 | データベース: PDB / ID: 8y81 |
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タイトル | Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri |
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要素 | - (High affinity immunoglobulin epsilon receptor subunit ...) x 3
- Immunoglobulin heavy constant epsilon
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キーワード | IMMUNE SYSTEM / complex / antibody |
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機能・相同性 | 機能・相同性情報
Fc epsilon receptor (FCERI) signaling / IgE receptor activity / Fc-epsilon receptor I complex / Dectin-2 family / serotonin secretion / Role of LAT2/NTAL/LAB on calcium mobilization / FCERI mediated NF-kB activation / Platelet Adhesion to exposed collagen / GPVI-mediated activation cascade / Cell surface interactions at the vascular wall ...Fc epsilon receptor (FCERI) signaling / IgE receptor activity / Fc-epsilon receptor I complex / Dectin-2 family / serotonin secretion / Role of LAT2/NTAL/LAB on calcium mobilization / FCERI mediated NF-kB activation / Platelet Adhesion to exposed collagen / GPVI-mediated activation cascade / Cell surface interactions at the vascular wall / Fc receptor mediated stimulatory signaling pathway / T cell differentiation involved in immune response / FCERI mediated Ca+2 mobilization / negative regulation of mast cell apoptotic process / high-affinity IgE receptor activity / IgE B cell receptor complex / type I hypersensitivity / Fc-gamma receptor III complex / mast cell apoptotic process / mast cell activation / FCERI mediated MAPK activation / serotonin secretion by platelet / positive regulation of interleukin-3 production / eosinophil degranulation / Fc-gamma receptor signaling pathway / neutrophil activation involved in immune response / positive regulation of mast cell cytokine production / regulation of platelet activation / positive regulation of type III hypersensitivity / positive regulation of mast cell degranulation / IgE binding / positive regulation of type IIa hypersensitivity / type 2 immune response / positive regulation of protein localization to cell surface / regulation of release of sequestered calcium ion into cytosol / protein kinase C-activating G protein-coupled receptor signaling pathway / leukotriene biosynthetic process / positive regulation of type I hypersensitivity / interleukin-3-mediated signaling pathway / positive regulation of granulocyte macrophage colony-stimulating factor production / IgG binding / Neutrophil degranulation / phagocytosis, engulfment / mast cell degranulation / positive regulation of interleukin-4 production / antigen processing and presentation of exogenous peptide antigen via MHC class I / Fc-epsilon receptor signaling pathway / positive regulation of interleukin-10 production / cellular response to low-density lipoprotein particle stimulus / regulation of immune response / immunoglobulin mediated immune response / positive regulation of calcium-mediated signaling / positive regulation of phagocytosis / immunoglobulin complex, circulating / immunoglobulin receptor binding / SH2 domain binding / B cell differentiation / neutrophil chemotaxis / osteoclast differentiation / complement activation, classical pathway / establishment of localization in cell / protein localization to plasma membrane / integrin-mediated signaling pathway / calcium-mediated signaling / phosphoprotein binding / B cell receptor signaling pathway / receptor internalization / peptide antigen assembly with MHC class II protein complex / MHC class II protein complex / peptide antigen binding / antigen processing and presentation of exogenous peptide antigen via MHC class II / positive regulation of interleukin-6 production / positive regulation of tumor necrosis factor production / positive regulation of peptidyl-tyrosine phosphorylation / positive regulation of immune response / positive regulation of T cell activation / MHC class II protein complex binding / late endosome membrane / antibacterial humoral response / cell surface receptor signaling pathway / blood microparticle / endosome / defense response to bacterium / immune response / protein heterodimerization activity / lysosomal membrane / external side of plasma membrane / innate immune response / protein kinase binding / cell surface / signal transduction / protein homodimerization activity / extracellular exosome / extracellular region / identical protein binding / plasma membrane / cytoplasm類似検索 - 分子機能 High affinity immunoglobulin epsilon receptor subunit gamma / CD20-like family / Membrane-spanning 4-domains subfamily A / CD20-like family / T-cell surface glycoprotein CD3 zeta subunit/High affinity IgE receptor gamma subunit / T-cell surface glycoprotein CD3 zeta chain / Immunoreceptor tyrosine-based activation motif / Phosphorylated immunoreceptor signalling ITAM / ITAM motif mammalian type profile. / Immunoreceptor tyrosine-based activation motif ...High affinity immunoglobulin epsilon receptor subunit gamma / CD20-like family / Membrane-spanning 4-domains subfamily A / CD20-like family / T-cell surface glycoprotein CD3 zeta subunit/High affinity IgE receptor gamma subunit / T-cell surface glycoprotein CD3 zeta chain / Immunoreceptor tyrosine-based activation motif / Phosphorylated immunoreceptor signalling ITAM / ITAM motif mammalian type profile. / Immunoreceptor tyrosine-based activation motif / Immunoglobulin domain / Immunoglobulin / Immunoglobulin domain / Immunoglobulin subtype / Immunoglobulin / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulin-like fold類似検索 - ドメイン・相同性 CHOLESTEROL HEMISUCCINATE / Immunoglobulin heavy constant epsilon / High affinity immunoglobulin epsilon receptor subunit alpha / High affinity immunoglobulin epsilon receptor subunit beta / High affinity immunoglobulin epsilon receptor subunit gamma類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Rattus norvegicus (ドブネズミ) |
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手法 | 電子顕微鏡法 / 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 2.89 Å |
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データ登録者 | Du, S. / Deng, M.J. / Xiao, J.Y. |
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資金援助 | 1件 |
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引用 | ジャーナル: To Be Published タイトル: Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri 著者: Du, S. / Deng, M.J. / Xiao, J.Y. |
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履歴 | 登録 | 2024年2月5日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2024年7月10日 | Provider: repository / タイプ: Initial release |
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