root morphogenesis / trichome morphogenesis / cytokinesis by cell plate formation / adaxial/abaxial pattern specification / leaf morphogenesis / response to high light intensity / plant-type cell wall / developmental process / plasmodesma / plant-type vacuole ...root morphogenesis / trichome morphogenesis / cytokinesis by cell plate formation / adaxial/abaxial pattern specification / leaf morphogenesis / response to high light intensity / plant-type cell wall / developmental process / plasmodesma / plant-type vacuole / chloroplast envelope / vacuole / response to UV-B / response to osmotic stress / nucleocytoplasmic transport / plastid / endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / protein-RNA complex assembly / maturation of LSU-rRNA / response to salt stress / endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / cytosolic ribosome / response to cold / ribosomal large subunit biogenesis / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / chloroplast / maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of SSU-rRNA / small-subunit processome / translational initiation / modification-dependent protein catabolic process / protein tag activity / rRNA processing / peroxisome / ribosomal small subunit assembly / ribosome biogenesis / ribosomal small subunit biogenesis / 5S rRNA binding / small ribosomal subunit / ribosomal large subunit assembly / response to oxidative stress / small ribosomal subunit rRNA binding / cytosolic small ribosomal subunit / large ribosomal subunit rRNA binding / cytosolic large ribosomal subunit / cytoplasmic translation / defense response to bacterium / negative regulation of translation / rRNA binding / structural constituent of ribosome / protein ubiquitination / ribosome / translation / ribonucleoprotein complex / cell division / mRNA binding / ubiquitin protein ligase binding / nucleolus / endoplasmic reticulum / mitochondrion / RNA binding / extracellular region / zinc ion binding / nucleoplasm / nucleus / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能
Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / : / Ribosomal protein L28e / : / Ribosomal protein L23 / Ribosomal protein L2, archaeal-type / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / metallochaperone-like domain ...Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / : / Ribosomal protein L28e / : / Ribosomal protein L23 / Ribosomal protein L2, archaeal-type / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / metallochaperone-like domain / TRASH domain / : / Ribosomal protein S26e signature. / Ribosomal protein L41 / Ribosomal protein L41 / Ribosomal protein S21e, conserved site / Ribosomal protein S21e signature. / Ribosomal protein L13e, conserved site / Ribosomal protein L13e signature. / Ribosomal protein S26e / Ribosomal protein S26e superfamily / Ribosomal protein S26e / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein S5, eukaryotic/archaeal / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein S21e / Ribosomal protein S21e superfamily / Ribosomal protein S21e / Ribosomal protein L13e / Ribosomal protein L13e / Ribosomal protein S19e, conserved site / Ribosomal protein S19e signature. / Ribosomal protein S2, eukaryotic / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / Ribosomal protein L19, eukaryotic / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein L19/L19e conserved site / Ribosomal protein L19e signature. / Ribosomal protein L44e signature. / 40S Ribosomal protein S10 / 60S ribosomal protein L18a/ L20, eukaryotes / Ribosomal protein L10e / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / Plectin/S10, N-terminal / Plectin/S10 domain / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein S30 / Ribosomal protein S30 / Ribosomal protein S10, eukaryotic/archaeal / : / Ribosomal protein L23/L25, N-terminal / Ribosomal protein L23, N-terminal domain / : / Ribosomal L40e family / Ribosomal protein S7e signature. / Ribosomal protein S8e subdomain, eukaryotes / Ribosomal protein L30e signature 1. / Ribosomal protein L36e signature. / Ribosomal protein S25 / S25 ribosomal protein / Ribosomal protein L44e / Ribosomal protein L44 / 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a / Ribosomal protein L35Ae, conserved site / Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A / Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A / Ribosomal protein 60S L18 and 50S L18e / Ribosomal protein L35Ae signature. / Ribosomal_L40e / Ribosomal protein L40e / Ribosomal protein L40e superfamily / Ribosomal protein S17e, conserved site / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal protein S17e signature. / Ribosomal protein L27e / Ribosomal protein L27e superfamily / Ribosomal L27e protein family / Ribosomal protein S2, eukaryotic/archaeal / : / Ribosomal Protein L6, KOW domain / Ribosomal protein S3Ae, conserved site / Ribosomal protein S3Ae signature. / Ribosomal protein L39e, conserved site / Ribosomal protein L39e signature. / 60S ribosomal protein L35 / Ribosomal protein L30e signature 2. / Ribosomal protein L30e, conserved site / 40S ribosomal protein S29/30S ribosomal protein S14 type Z 類似検索 - ドメイン・相同性
Ribosomal protein L18ae/LX family protein / Ubiquitin-ribosomal protein eL40z fusion protein / Ribosomal protein L30/L7 family protein / 60S ribosomal protein L29 / Large ribosomal subunit protein eL38z/eL38y / Large ribosomal subunit protein eL42z/eL42y / Large ribosomal subunit protein eL15z / Large ribosomal subunit protein eL28z / Small ribosomal subunit protein uS17z / Large ribosomal subunit protein uL3z ...Ribosomal protein L18ae/LX family protein / Ubiquitin-ribosomal protein eL40z fusion protein / Ribosomal protein L30/L7 family protein / 60S ribosomal protein L29 / Large ribosomal subunit protein eL38z/eL38y / Large ribosomal subunit protein eL42z/eL42y / Large ribosomal subunit protein eL15z / Large ribosomal subunit protein eL28z / Small ribosomal subunit protein uS17z / Large ribosomal subunit protein uL3z / Small ribosomal subunit protein uS13z/uS13y/uS13x / Small ribosomal subunit protein eS28x / Large ribosomal subunit protein eL13z / Large ribosomal subunit protein uL5z / Small ribosomal subunit protein uS8z/uS8w / Large ribosomal subunit protein uL2z / Small ribosomal subunit protein uS12y / Small ribosomal subunit protein eS26y / Large ribosomal subunit protein uL6z/uL6y / Large ribosomal subunit protein eL32z / Large ribosomal subunit protein uL15x / Small ribosomal subunit protein eS30z/eS30y/eS30x / Large ribosomal subunit protein uL14x/uL14z/uL14y / Large ribosomal subunit protein uL24z / Large ribosomal subunit protein eL27x / Large ribosomal subunit protein eL39z/eL39x / Small ribosomal subunit protein uS7y / Small ribosomal subunit protein eS6y / Small ribosomal subunit protein uS15y / Small ribosomal subunit protein eS32 eS32z/eS32y/eS32x/eS32w/eS32v / Small ribosomal subunit protein uS2z / Large ribosomal subunit protein uL16y / Small ribosomal subunit protein eS21y / Small ribosomal subunit protein eS1y / Large ribosomal subunit protein eL24z / Large ribosomal subunit protein eL34z / Large ribosomal subunit protein eL21z/eL21y / Small ribosomal subunit protein uS14z/uS14y/uS14x / Large ribosomal subunit protein uL18z / Small ribosomal subunit protein eS24y / Small ribosomal subunit protein eS7x / Large ribosomal subunit protein eL37z / Large ribosomal subunit protein eL43y / Small ribosomal subunit protein eS4x / Large ribosomal subunit protein eL30y / Small ribosomal subunit protein uS5y/uS5u/uS5v / Small ribosomal subunit protein eS8z / Large ribosomal subunit protein uL22z / Large ribosomal subunit protein eL18x / Large ribosomal subunit protein eL33y / Large ribosomal subunit protein eL6y / Small ribosomal subunit protein uS11y / Small ribosomal subunit protein uS4y / Small ribosomal subunit protein eS19x / Small ribosomal subunit protein uS19y / Large ribosomal subunit protein uL13y / Small ribosomal subunit protein eS17w / Large ribosomal subunit protein eL8y / Small ribosomal subunit protein eS27y / Large ribosomal subunit protein eL36y / Large ribosomal subunit protein uL23y / Large ribosomal subunit protein uL29x / Large ribosomal subunit protein eL22z / Large ribosomal subunit protein uL4z / Small ribosomal subunit protein uS3z / Small ribosomal subunit protein uS9z / Large ribosomal subunit protein eL19x / Large ribosomal subunit protein eL31y / Small ribosomal subunit protein uS10y / Small ribosomal subunit protein eS10z / Small ribosomal subunit protein eS25w / Large ribosomal subunit protein eL14y 類似検索 - 構成要素
Biotechnology and Biological Sciences Research Council (BBSRC)
BB/N013158/1
英国
European Research Council (ERC)
323052
European Union
引用
ジャーナル: Science / 年: 2026 タイトル: Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate. 著者: Donghwi Ko / Raili Ruonala / Alexandre Faille / Eva Hellmann / Hanna Help / Huili Liu / Ronni Nielsen / Anders Haakonsson / Nuria De Diego / Anja Paatero / Mariia V Shcherbii / Karolina ...著者: Donghwi Ko / Raili Ruonala / Alexandre Faille / Eva Hellmann / Hanna Help / Huili Liu / Ronni Nielsen / Anders Haakonsson / Nuria De Diego / Anja Paatero / Mariia V Shcherbii / Karolina Stefanowicz / Sanja Ćavar Zeljković / Tine Drud Lundager Rasmussen / Ondrej Novak / Zsuzsanna Bodi / Gugan Eswaran / Brecht Wybouw / Matthieu Bourdon / Cristina Urbez / Xiaonan Liu / Kari Salokas / Tiina Öhman / Tanya Waldie / Petri Törönen / Sedeer El-Showk / Martin Balcerowicz / Fabrice Besnard / Xiaomin Liu / Patrick Perkins / Serina Mazzoni-Putman / Julia P Vainonen / Maija Sierla / Mikko J Frilander / Susanne Mandrup / Teva Vernoux / Karin Ljung / Alejandro Ferrando / Miguel A Blazquez / Liisa Holm / Rupert Fray / Markku Varjosalo / Ottoline Leyser / Ville O Paavilainen / Ari Pekka Mähönen / Anna Stepanova / Jose Alonso / Steffen Heber / Robert Malinowski / Finn Kirpekar / Alan J Warren / Ykä Helariutta / 要旨: Polyamines are often associated with ribosomes and are thought to stabilize their integrity. In , the polyamine thermospermine (tSpm) affects xylem cell fate. tSpm induces translation of SUPPRESSOR- ...Polyamines are often associated with ribosomes and are thought to stabilize their integrity. In , the polyamine thermospermine (tSpm) affects xylem cell fate. tSpm induces translation of SUPPRESSOR-OF-ACAULIS51 (SAC51) and SAC51-LIKEs (SACLs), which inhibit heterodimerization of the xylem development proteins LONESOME-HIGHWAY (LHW) and TARGET-OF-MONOPTEROS5. Here, we report a methyltransferase, OVERACHIEVER, that methylates the peptidyl transferase center of the 25 ribosomal RNA (rRNA). Residue mU2952 promotes functional tSpm binding to a specific site connecting the P-site transfer RNA (tRNA) with rRNA residues in the peptidyl transferase center. This interaction enhances the translation of SACLs but inhibits that of LHW. Our study uncovers the dependency between a conserved rRNA base methylation and a polyamine in orchestrating cell fate decisions, highlighting a role for the ribosome chemical landscape in translational regulation.