- EMDB-31030: Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucl... -
+
データを開く
IDまたはキーワード:
読み込み中...
-
基本情報
登録情報
データベース: EMDB / ID: EMD-31030
タイトル
Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome
マップデータ
試料
複合体: Yeast Orc1 BAH domain in complex with 147-bp nucleosome
複合体: Histone
タンパク質・ペプチド: Histone H3
タンパク質・ペプチド: Histone H4
タンパク質・ペプチド: Histone H2A.2
タンパク質・ペプチド: Histone H2B.2
複合体: DNA
DNA: DNA (147-mer)
DNA: DNA (147-mer)
複合体: Origin recognition complex subunit 1
タンパク質・ペプチド: Origin recognition complex subunit 1
機能・相同性
機能・相同性情報
CDC6 association with the ORC:origin complex / sexual sporulation resulting in formation of a cellular spore / HATs acetylate histones / global genome nucleotide-excision repair / RNA polymerase I upstream activating factor complex / maintenance of rDNA / Condensation of Prophase Chromosomes / SIRT1 negatively regulates rRNA expression / Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 / Assembly of the ORC complex at the origin of replication ...CDC6 association with the ORC:origin complex / sexual sporulation resulting in formation of a cellular spore / HATs acetylate histones / global genome nucleotide-excision repair / RNA polymerase I upstream activating factor complex / maintenance of rDNA / Condensation of Prophase Chromosomes / SIRT1 negatively regulates rRNA expression / Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 / Assembly of the ORC complex at the origin of replication / nuclear origin of replication recognition complex / HDACs deacetylate histones / pre-replicative complex assembly involved in nuclear cell cycle DNA replication / Activation of the pre-replicative complex / nuclear pre-replicative complex / Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks / Activation of ATR in response to replication stress / DNA replication preinitiation complex / replication fork protection complex / mitotic DNA replication checkpoint signaling / Oxidative Stress Induced Senescence / RMTs methylate histone arginines / SUMOylation of chromatin organization proteins / silent mating-type cassette heterochromatin formation / positive regulation of transcription by RNA polymerase I / Orc1 removal from chromatin / RNA Polymerase I Promoter Escape / nucleolar large rRNA transcription by RNA polymerase I / DNA replication origin binding / rRNA transcription / Estrogen-dependent gene expression / DNA replication initiation / Ub-specific processing proteases / CENP-A containing nucleosome / heterochromatin organization / nucleosome binding / nucleosomal DNA binding / structural constituent of chromatin / nucleosome / nucleosome assembly / chromatin organization / protein heterodimerization activity / DNA repair / chromatin binding / regulation of DNA-templated transcription / ATP hydrolysis activity / DNA binding / nucleoplasm / ATP binding / nucleus / metal ion binding 類似検索 - 分子機能