登録情報 | データベース: EMDB / ID: EMD-27271 |
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タイトル | CryoEM structure of Western equine encephalitis virus VLP in complex with the avian MXRA8 receptor |
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マップデータ | Map of WEEV-VLP bound to MXRA8 asymmetric unit. |
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試料 | - 複合体: Western equine encephalitis virus VLP in complex with avian MXRA8 receptor
- タンパク質・ペプチド: E1 envelope glycoprotein
- タンパク質・ペプチド: E2 envelope glycoprotein
- タンパク質・ペプチド: Matrix remodeling-associated protein 8
- リガンド: 2-acetamido-2-deoxy-beta-D-glucopyranose
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キーワード | WEEV / MXRA8 / Receptor / Alphavirus / Avian / VLP / Structural Genomics / PSI-2 / Protein Structure Initiative / Center for Structural Genomics of Infectious Diseases / CSGID / VIRUS LIKE PARTICLE |
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機能・相同性 | 機能・相同性情報
T=4 icosahedral viral capsid / host cell cytoplasm / cell adhesion / symbiont entry into host cell / serine-type endopeptidase activity / fusion of virus membrane with host endosome membrane / virion attachment to host cell / host cell plasma membrane / structural molecule activity / virion membrane ...T=4 icosahedral viral capsid / host cell cytoplasm / cell adhesion / symbiont entry into host cell / serine-type endopeptidase activity / fusion of virus membrane with host endosome membrane / virion attachment to host cell / host cell plasma membrane / structural molecule activity / virion membrane / proteolysis / plasma membrane / cytoplasm類似検索 - 分子機能 Matrix remodeling-associated protein 8 / Alphavirus E2 glycoprotein, domain B / Peptidase S3, togavirin / Alphavirus E2 glycoprotein / Alphavirus E3 spike glycoprotein / Alphavirus E1 glycoprotein / Alphavirus E2 glycoprotein, domain A / Alphavirus E2 glycoprotein, domain C / Alphavirus E2 glycoprotein / Alphavirus core protein ...Matrix remodeling-associated protein 8 / Alphavirus E2 glycoprotein, domain B / Peptidase S3, togavirin / Alphavirus E2 glycoprotein / Alphavirus E3 spike glycoprotein / Alphavirus E1 glycoprotein / Alphavirus E2 glycoprotein, domain A / Alphavirus E2 glycoprotein, domain C / Alphavirus E2 glycoprotein / Alphavirus core protein / Alphavirus E3 glycoprotein / Alphavirus E1 glycoprotein / Alphavirus core protein (CP) domain profile. / Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamily / Flavivirus glycoprotein, central and dimerisation domain superfamily / Flaviviral glycoprotein E, dimerisation domain / Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin E-set / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / Immunoglobulin-like fold類似検索 - ドメイン・相同性 Matrix remodeling-associated protein 8 / Structural polyprotein類似検索 - 構成要素 |
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生物種 | Western equine encephalitis virus (西部ウマ脳炎ウイルス) / Asarcornis scutulata (カモ) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 4.74 Å |
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データ登録者 | Zimmerman MI / Fremont DH |
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資金援助 | 米国, 1件 Organization | Grant number | 国 |
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National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | HHSN272201700060C | 米国 |
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引用 | ジャーナル: To Be Published タイトル: Alternate domain repeat usage in an alphavirus entry receptor enables host species expansion 著者: Zimmerman O / Zimmerman MI / Nelson CA / Raju S / Errico JM / Madden EA / Hassan AO / VanBlargan LA / Kim AS / Adams LJ / Basore K / Whitener BM / Earnest JT / Holmes AC / Ebel GD / Zmasek C ...著者: Zimmerman O / Zimmerman MI / Nelson CA / Raju S / Errico JM / Madden EA / Hassan AO / VanBlargan LA / Kim AS / Adams LJ / Basore K / Whitener BM / Earnest JT / Holmes AC / Ebel GD / Zmasek C / Scheuermann RH / Fremont DH / Diamond MS |
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履歴 | 登録 | 2022年6月13日 | - |
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ヘッダ(付随情報) 公開 | 2023年12月20日 | - |
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マップ公開 | 2023年12月20日 | - |
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更新 | 2023年12月20日 | - |
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現状 | 2023年12月20日 | 処理サイト: RCSB / 状態: 公開 |
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