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- EMDB-16155: Structure of rabbit 80S ribosome translating beta-tubulin in comp... -

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基本情報

登録情報
データベース: EMDB / ID: EMD-16155
タイトルStructure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
マップデータSharpened map of the 60S subunit bound to SCAPER and TTC5
試料
  • 複合体: rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
    • RNA: x 3種
    • タンパク質・ペプチド: x 48種
  • リガンド: x 2種
キーワードtubulin auto-regulation mRNA decay translation SCAPER / RIBOSOME
機能・相同性
機能・相同性情報


ooplasm / odontoblast differentiation / positive regulation of mRNA catabolic process / sperm head / cytoskeleton-dependent intracellular transport / GTPase activating protein binding / regulation of G1 to G0 transition / exit from mitosis / positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator / regulation of translation involved in cellular response to UV ...ooplasm / odontoblast differentiation / positive regulation of mRNA catabolic process / sperm head / cytoskeleton-dependent intracellular transport / GTPase activating protein binding / regulation of G1 to G0 transition / exit from mitosis / positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator / regulation of translation involved in cellular response to UV / natural killer cell mediated cytotoxicity / protein-DNA complex disassembly / positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator / optic nerve development / antral ovarian follicle growth / retinal ganglion cell axon guidance / G1 to G0 transition / intercellular bridge / regulation of synapse organization / nuclear envelope lumen / seminiferous tubule development / MHC class I protein binding / microtubule-based process / positive regulation of signal transduction by p53 class mediator / ubiquitin ligase inhibitor activity / protein-RNA complex assembly / spindle assembly / negative regulation of ubiquitin-dependent protein catabolic process / cellular response to actinomycin D / rough endoplasmic reticulum / Loss of Nlp from mitotic centrosomes / Loss of proteins required for interphase microtubule organization from the centrosome / Recruitment of mitotic centrosome proteins and complexes / Recruitment of NuMA to mitotic centrosomes / Anchoring of the basal body to the plasma membrane / DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest / cellular response to starvation / AURKA Activation by TPX2 / maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / maturation of LSU-rRNA / ribosomal large subunit biogenesis / positive regulation of translation / Regulation of TP53 Activity through Methylation / structural constituent of cytoskeleton / cellular response to gamma radiation / mitotic spindle / transcription coactivator binding / mRNA 5'-UTR binding / microtubule cytoskeleton organization / cytoplasmic ribonucleoprotein granule / rRNA processing / microtubule cytoskeleton / azurophil granule lumen / Regulation of PLK1 Activity at G2/M Transition / antimicrobial humoral immune response mediated by antimicrobial peptide / ribosome biogenesis / ribosome binding / retina development in camera-type eye / regulation of translation / mitotic cell cycle / cell body / 5S rRNA binding / cytoplasmic vesicle / large ribosomal subunit rRNA binding / spermatogenesis / defense response to Gram-negative bacterium / killing of cells of another organism / microtubule / cytosolic large ribosomal subunit / Potential therapeutics for SARS / nucleic acid binding / cytoplasmic translation / tRNA binding / postsynaptic density / cytoskeleton / protein stabilization / rRNA binding / ribosome / nuclear speck / structural constituent of ribosome / mitochondrial matrix / ribonucleoprotein complex / translation / membrane raft / protein domain specific binding / cell division / DNA repair / GTPase activity / mRNA binding / ubiquitin protein ligase binding / synapse / DNA damage response / chromatin binding / positive regulation of cell population proliferation / Neutrophil degranulation / positive regulation of gene expression / protein-containing complex binding / nucleolus / GTP binding / structural molecule activity
類似検索 - 分子機能
S phase cyclin A-associated protein in the endoplasmic reticulum, N-terminal / S phase cyclin A-associated protein in the endoplasmic reticulum / Tetratricopeptide repeat protein 5, OB fold domain / TTC5, OB fold domain superfamily / Tetratricopeptide repeat protein 5 OB fold domain / Zinc-finger of C2H2 type / 60s Acidic ribosomal protein / Matrin/U1-C-like, C2H2-type zinc finger / U1-like zinc finger / 60S acidic ribosomal protein P0 ...S phase cyclin A-associated protein in the endoplasmic reticulum, N-terminal / S phase cyclin A-associated protein in the endoplasmic reticulum / Tetratricopeptide repeat protein 5, OB fold domain / TTC5, OB fold domain superfamily / Tetratricopeptide repeat protein 5 OB fold domain / Zinc-finger of C2H2 type / 60s Acidic ribosomal protein / Matrin/U1-C-like, C2H2-type zinc finger / U1-like zinc finger / 60S acidic ribosomal protein P0 / : / Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / Ribosomal protein L30e / Ribosomal protein L28e / Ribosomal L15/L27a, N-terminal / : / Ribosomal protein L23 / 50S ribosomal protein L10, insertion domain superfamily / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / 60S ribosomal protein L10P, insertion domain / Insertion domain in 60S ribosomal protein L10P / Ribosomal protein L41 / Ribosomal protein L41 / metallochaperone-like domain / TRASH domain / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein L38e / Ribosomal protein L38e superfamily / Ribosomal L38e protein family / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L44e signature. / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein L10e / Ribosomal protein L13e / Ribosomal protein L13e / : / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / Ribosomal protein L44e / Ribosomal protein L44 / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein L6e signature. / Ribosomal protein L30e signature 1. / Ribosomal protein L30e signature 2. / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal protein L23/L25, N-terminal / Ribosomal protein L30e, conserved site / Ribosomal protein L23, N-terminal domain / Ribosomal protein L27e / Ribosomal protein L27e superfamily / Ribosomal L27e protein family / Ribosomal protein L36e signature. / Ribosomal protein L39e, conserved site / Ribosomal protein L39e signature. / Ribosomal protein L34Ae / Ribosomal protein L34e / Ribosomal protein L35Ae, conserved site / Ribosomal protein L35Ae signature. / Ribosomal protein L30/YlxQ / 60S ribosomal protein L35 / Ribosomal Protein L6, KOW domain / Ribosomal protein L7A/L8 / Ribosomal protein L6e / Tubulin-beta mRNA autoregulation signal. / TPR repeat region circular profile. / 60S ribosomal protein L6E / Beta tubulin, autoregulation binding site / Ribosomal protein L37ae / Ribosomal L37ae protein family / 60S ribosomal protein L4, C-terminal domain / 60S ribosomal protein L4 C-terminal domain / Ribosomal protein L31e, conserved site / Ribosomal protein L31e signature. / Ribosomal protein L36e / Ribosomal protein L36e domain superfamily / Ribosomal protein L36e / Beta tubulin / Ribosomal protein L39e / Ribosomal protein L14e domain / Ribosomal protein L39e domain superfamily / Ribosomal L39 protein / Ribosomal protein L14 / Ribosomal protein L35A / Ribosomal protein L5 eukaryotic/L18 archaeal / Ribosomal protein L35Ae / Ribosomal large subunit proteins 60S L5, and 50S L18 / Ribosomal protein L35A superfamily / Ribosomal protein L32e, conserved site / Ribosomal protein L32e signature. / Ribosomal protein L6, conserved site-2 / Ribosomal protein L14 / Ribosomal protein L6 signature 2.
類似検索 - ドメイン・相同性
Small ribosomal subunit protein eS32 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL16 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 ...Small ribosomal subunit protein eS32 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL16 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Large ribosomal subunit protein eL29 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 / Large ribosomal subunit protein eL6 / Large ribosomal subunit protein uL11 / Large ribosomal subunit protein uL15 / Large ribosomal subunit protein uL10 / Large ribosomal subunit protein uL24 / Large ribosomal subunit protein eL8 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein eL43 / Large ribosomal subunit protein uL18 / Large ribosomal subunit protein eL14 / Large ribosomal subunit protein eL15 / Large ribosomal subunit protein uL14 / Large ribosomal subunit protein eL30 / Large ribosomal subunit protein eL13 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein eL36 / Large ribosomal subunit protein uL5 / Large ribosomal subunit protein eL27 / Large ribosomal subunit protein eL38 / Large ribosomal subunit protein eL42 / Large ribosomal subunit protein eL32 / Large ribosomal subunit protein eL28 / Large ribosomal subunit protein eL34 / Tubulin beta chain / Tetratricopeptide repeat protein 5 / S phase cyclin A-associated protein in the endoplasmic reticulum / Large ribosomal subunit protein eL37
類似検索 - 構成要素
生物種Oryctolagus cuniculus (ウサギ) / rabbit (ウサギ) / Homo sapiens (ヒト)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 2.8 Å
データ登録者Hopfler M / Absmeier E / Passmore LA / Hegde RS
資金援助 英国, European Union, ドイツ, スイス, 米国, 7件
OrganizationGrant number国
Medical Research Council (MRC, United Kingdom)MC_UP_A022_1007 英国
Medical Research Council (MRC, United Kingdom)MC_U105192715 英国
European Molecular Biology Organization (EMBO)ALTF 116-2020European Union
H2020 Marie Curie Actions of the European Commission101029853European Union
German Research Foundation (DFG)429892960 ドイツ
Swiss National Science FoundationPCEFP3_194312 スイス
Damon Runyon Cancer Research FoundationDRG:2279-16 米国
引用ジャーナル: Mol Cell / 年: 2023
タイトル: Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.
著者: Markus Höpfler / Eva Absmeier / Sew-Yeu Peak-Chew / Evangelia Vartholomaiou / Lori A Passmore / Ivana Gasic / Ramanujan S Hegde /
要旨: Microtubules play crucial roles in cellular architecture, intracellular transport, and mitosis. The availability of free tubulin subunits affects polymerization dynamics and microtubule function. ...Microtubules play crucial roles in cellular architecture, intracellular transport, and mitosis. The availability of free tubulin subunits affects polymerization dynamics and microtubule function. When cells sense excess free tubulin, they trigger degradation of the encoding mRNAs, which requires recognition of the nascent polypeptide by the tubulin-specific ribosome-binding factor TTC5. How TTC5 initiates the decay of tubulin mRNAs is unknown. Here, our biochemical and structural analysis reveals that TTC5 recruits the poorly studied protein SCAPER to the ribosome. SCAPER, in turn, engages the CCR4-NOT deadenylase complex through its CNOT11 subunit to trigger tubulin mRNA decay. SCAPER mutants that cause intellectual disability and retinitis pigmentosa in humans are impaired in CCR4-NOT recruitment, tubulin mRNA degradation, and microtubule-dependent chromosome segregation. Our findings demonstrate how recognition of a nascent polypeptide on the ribosome is physically linked to mRNA decay factors via a relay of protein-protein interactions, providing a paradigm for specificity in cytoplasmic gene regulation.
履歴
登録2022年11月17日-
ヘッダ(付随情報) 公開2023年7月5日-
マップ公開2023年7月5日-
更新2023年7月19日-
現状2023年7月19日処理サイト: PDBe / 状態: 公開

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構造の表示

添付画像

emd_16155.png

ダウンロードとリンク

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マップ

ファイルダウンロード / ファイル: emd_16155.map.gz / 形式: CCP4 / 大きさ: 536.4 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
注釈Sharpened map of the 60S subunit bound to SCAPER and TTC5
ボクセルのサイズX=Y=Z: 0.829 Å
密度
表面レベル登録者による: 0.008
最小 - 最大-0.027295088 - 0.064459495
平均 (標準偏差)0.00013388802 (±0.0019254888)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin000
サイズ520520520
Spacing520520520
セルA=B=C: 431.08 Å
α=β=γ: 90.0 °

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添付データ

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マスク #1

ファイルemd_16155_msk_1.map
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追加マップ: unsharpened map of the 80S ribosome after focussed...

ファイルemd_16155_additional_1.map
注釈unsharpened map of the 80S ribosome after focussed classification around the expansion segment
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追加マップ: unsharpened map of the 80S ribosome after focussed...

ファイルemd_16155_additional_2.map
注釈unsharpened map of the 80S ribosome after focussed classification around the P-site tRNA
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追加マップ: unsharpened map of the 80S ribosome after focussed...

ファイルemd_16155_additional_3.map
注釈unsharpened map of the 80S ribosome after focussed classification around SCAPER
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ハーフマップ: Half-map 1 of the 60S subunit bound to SCAPER and TTC5

ファイルemd_16155_half_map_1.map
注釈Half-map 1 of the 60S subunit bound to SCAPER and TTC5
投影像・断面図
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ハーフマップ: Half-map 2 of the 60S subunit bound to SCAPER and TTC5

ファイルemd_16155_half_map_2.map
注釈Half-map 2 of the 60S subunit bound to SCAPER and TTC5
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試料の構成要素

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全体 : rabbit 80S ribosome translating beta-tubulin in complex with tetr...

全体名称: rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
要素
  • 複合体: rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
    • RNA: 28S ribosomal RNA
    • RNA: 5S ribosomal RNA
    • RNA: 5.8S ribosomal RNA
    • タンパク質・ペプチド: Nascent polypeptide-associated complex subunit alpha N-terminal region
    • タンパク質・ペプチド: 60S ribosomal protein L8
    • タンパク質・ペプチド: Ribosomal protein L3
    • タンパク質・ペプチド: 60S ribosomal protein L4
    • タンパク質・ペプチド: Ribosomal_L18_c domain-containing protein
    • タンパク質・ペプチド: 60S ribosomal protein L6
    • タンパク質・ペプチド: 60S ribosomal protein L7
    • タンパク質・ペプチド: 60S ribosomal protein L7a
    • タンパク質・ペプチド: 60S ribosomal protein L9
    • タンパク質・ペプチド: Ribosomal protein L10
    • タンパク質・ペプチド: 60S ribosomal protein L11
    • タンパク質・ペプチド: 60S ribosomal protein L13
    • タンパク質・ペプチド: 60S ribosomal protein L14
    • タンパク質・ペプチド: Ribosomal protein L15
    • タンパク質・ペプチド: 60S ribosomal protein L13a
    • タンパク質・ペプチド: 60S ribosomal protein L17
    • タンパク質・ペプチド: Ribosomal protein L18
    • タンパク質・ペプチド: 60S ribosomal protein L19
    • タンパク質・ペプチド: 60S ribosomal protein L18a
    • タンパク質・ペプチド: 60S ribosomal protein L21
    • タンパク質・ペプチド: 60S ribosomal protein L22
    • タンパク質・ペプチド: 60S ribosomal protein L23
    • タンパク質・ペプチド: Ribosomal protein L24
    • タンパク質・ペプチド: Ribosomal_L23eN domain-containing protein
    • タンパク質・ペプチド: Ribosomal protein L26
    • タンパク質・ペプチド: 60S ribosomal protein L27
    • タンパク質・ペプチド: 60S ribosomal protein L27a
    • タンパク質・ペプチド: 60S ribosomal protein L29
    • タンパク質・ペプチド: 60S ribosomal protein L30
    • タンパク質・ペプチド: 60S ribosomal protein L31
    • タンパク質・ペプチド: Ribosomal protein L32
    • タンパク質・ペプチド: 60S ribosomal protein L35a
    • タンパク質・ペプチド: 60S ribosomal protein L34
    • タンパク質・ペプチド: 60S ribosomal protein L35
    • タンパク質・ペプチド: 60S ribosomal protein L36
    • タンパク質・ペプチド: Ribosomal protein L37
    • タンパク質・ペプチド: 60S ribosomal protein L38
    • タンパク質・ペプチド: 60S ribosomal protein L39-like
    • タンパク質・ペプチド: Ubiquitin-60S ribosomal protein L40
    • タンパク質・ペプチド: 60S ribosomal protein L41
    • タンパク質・ペプチド: 60S ribosomal protein L36a-like
    • タンパク質・ペプチド: 60S ribosomal protein L37a
    • タンパク質・ペプチド: 60S ribosomal protein L28
    • タンパク質・ペプチド: 60S acidic ribosomal protein P0
    • タンパク質・ペプチド: 60S ribosomal protein L12
    • タンパク質・ペプチド: S phase cyclin A-associated protein in the endoplasmic reticulum
    • タンパク質・ペプチド: Tetratricopeptide repeat protein 5
    • タンパク質・ペプチド: Tubulin beta chain
  • リガンド: MAGNESIUM ION
  • リガンド: ZINC ION

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超分子 #1: rabbit 80S ribosome translating beta-tubulin in complex with tetr...

超分子名称: rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER)
タイプ: complex / ID: 1 / 親要素: 0 / 含まれる分子: #1-#51
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)

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分子 #1: 28S ribosomal RNA

分子名称: 28S ribosomal RNA / タイプ: rna / ID: 1 / コピー数: 1
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 1.418701625 MDa
配列文字列: CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAA AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGAAA UGUGGCGUAC G GAAGACCC ...文字列:
CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAA AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGAAA UGUGGCGUAC G GAAGACCC ACUCCCCGGC GCCGGGGGGC CCAAGUCCUU CUGAUCGAGG CCCAGCCCGU GGACGGUGUG AGGCCGGUAG CG GCCCCCG GCGCGCCGGG CCCGGGUCUU CCCGGAGUCG GGUUGCUUGG GAAUGCAGCC CAAAGCGGGU GGUAAACUCC AUC UAAGGC UAAAUACCGG CACGAGACCG AUAGUCAACA AGUACCGUAA GGGAAAGUUG AAAAGAACUU UGAAGAGAGA GUUC AAGAG GGCGUGAAAC CGUUAAGAGG UAAACGGGUG GGGUCCGCGC AGUCCGCCCG GAGGAUUCAA CCCGGCGGCG CGGUC CGGC CGUGCCGGCG GGGCGGAUCU CCCGCUCCCG UCGGCGGGGG ACCGCCCCCC GGCCGGCGAC CGGCCGCCGC CGGGCG CAU UUCCACCGCG GCGGUGCGCC GCGACCGGCU CCGGGACGGC UGGGAAGGCC CCGGCGGGGA AGGUGGCCCG GGGGCCC CG GGUGUUACAG CCCCGCCCCG GCAGCAGCAG CUCGCCGAAU CCCGGGGCCG AGGGAGCGAG ACCCGUGCGC CGCGCUCU C CCCCCUCGGG GGGGCCGGGC CACCCCUCCC ACGGCGCGAC CGCUGGGGCG GACUGUCCAG UGCGCCCCGG GCGGGUCGC GCCGUCGGGC CCGGGGGGCC ACGCGUCCCC CGCGAGCGCA CGGGGUCGGC GGCGAUGUCG GCUACCCACC CGACCCGUCU UGAAACACG GACCAAGGAG UCUAACACGU GCGCGAGUCG GGGGCUACGA AAGCCGCCGU GGCGCAAUGA AGGUGAAGGC C GGCGGCGC GCCGCCGGCC GAGGUGGGAU CCCGAGGCCU UCCAGUCCGC CGAGGGCGCA CCACCGGCCC GUCUCGCCCG CC GCGCCGG GGAGGUGGAG CACGAGCGCA CGUGUUAGGA CCCGAAAGAU GGUGAACUAU GCCUGGGCAG GGCGAAGCCA GAG GAAACU CUGGUGGAGG UCCGUAGCGG UCCUGACGUG CGAAUCGGUC GUCCGACCUG GGUAUAGGGG CGAAAGACUA AUCG AACCA UCUAGUAGCU GGUUCCCUCC AAAGUUUCCC UCAGGAUAGC UGGCGCUCUC GCAACCCCGC AGUUUUAUCC GGUAA AGCG AAUGAUUAGA GGUCUUGGGG CCGAAACGAU CUCAACCUAU UCUCAAACUU UAAAUGGGUA AGAAGCCCGG CUCGCU GGU GUGGAGCCGG GCGUGGAAUG CGAGUGCCUA GUGGGCCACU UUUGGUAAGC AGAACUGGCG CUGCGGGAUG AACCGAA CG CCGGGUUAAG GCGCCCGAUG CCGACGCUCA UCAGACCCCA GAAAAGGUGU UGGUUGAUAU AGACAGCAGG AUGGUGGC C AUGGAAGUCG GAAUCCGCUA AGGAGUGUGU AACAACUCAC CUGCCGAAUC AACUAGCCCU GAAAAUGGAU GGCGCUGGA GCGUCGGGCC CAUACCCGGC CGUCGCUGGC AGUCGGCAGA GCGAGAAAGA GAGUGGAGCG CGCCGCGGGA CUCCCCCGCG GGGGUCCCG GCCACCCCCC CCGCGGACGC UACGCCGCGA CGAGUAGGAG GGCCGCUGCG GUGAGCCUUG AAGCCUAGGG C GCGGGCCC GGGUGGAGCC GCCGCAGGUG CAGAUCUUGG UGGUAGUAGC AAAUAUUCAA ACGAGAACUU UGAAGGCCGA AG UGGAGAA GGGUUCCAUG UGAACAGCAG UUGAACAUGG GUCAGUCGGU CCUGAGAGAU GGGCGAGCGC CGUUCCGAAG GGA CGGGCG AUGGCCUCCG UUGCCCUCAG CCGAUCGAAA GGGAGUCGGG UUCAGAUCCC CGAAUCCGGA GUGGCGGAGA UGGG CGCCG CGAGGCGUCC AGUGCGGUAA CGCGACCGAU CCCGGAGAAG CCGGCGGGAG CCCCGGGGAG AGUUCUCUUU UCUUU GUGA AGGGCAGGGC GCCCUGGAAU GGGUUCGCCC CGAGAGAGGG GCCCGUGCCU UGGAAAGCGU CGCGGUUCCG GCGGCG UCC GGUGAGCUCU CGCUGGCCCU UGAAAAUCCG GGGGAGAGGG UGUAAAUCUC GCGCCGGGCC GUACCCAUAU CCGCAGC AG GUCUCCAAGG UGAACAGCCU CUGGCAUGUU GGAACAAUGU AGGUAAGGGA AGUCGGCAAG CCGGAUCCGU AACUUCGG G AUAAGGAUUG GCUCUAAGGG CUGGGUCGGU CGGGCUGGGG CGCGAAGCGG GGCUGGGCGC GCGCCGCGGC UGGACGAGG CGCCGCCGCC CCCCCCACGC CCGGGCGCCC UCCCCCGGCC GGGUCCGCUC CUCGCGCGCG CACGUGCGCC GUGGCGCGCG CCGCGCGCG CGGCCGAGCC CCGUCUCCCC CCCUCUCCCC UCCCGGGGCG GGGUGCGGGG AGGGGCGGGC GGGGCCGUCG C UCGCCGCG CGUGCGCGUC GCUGCGCGUG CGCCGCGCGG GGGUCCGGCG GGCCUCCGGA CGGGGGCUCC GGGCACCCGG GC ACCCGGG GGGCCGGCGG CGGCGGCGAC UCUGGACGCG AGCCGGGCCC UUCCCGUGGA UCGCCCCAGC UGCGGCGGGC GUC GCGGCC GCCCGGGGAG CCCGGCGGGC GCCGCGUGCG CGCGCGUGCG CGCCCGGGGU CGGGGGGGUG CGAGGCAGGG GAGC CCUCU CCUCCUCCCC CACCCCGGCG CCGCGGCGCC GCGCGUGCGC GCGCGGUCUC CCCCCGCCGG GUCCGCCCCC GGGGC CGCG GUUCCGCGCG GCGCCUCGCC UCGGCCGGCG CCUAGCAGCC GACUUAGAAC UGGUGCGGAC CAGGGGAAUC CGACUG UUU AAUUAAAACA AAGCAUCGCG AAGGCCCGCG GCGGGUGUUG ACGCGAUGUG AUUUCUGCCC AGUGCUCUGA AUGUCAA AG UGAAGAAAUU CAAUGAAGCG CGGGUAAACG GCGGGAGUAA CUAUGACUCU CUUAAGGUAG CCAAAUGCCU CGUCAUCU A AUUAGUGACG CGCAUGAAUG GAUGAACGAG AUUCCCACUG UCCCUACCUA CUAUCCAGCG AAACCACAGC CAAGGGAAC GGGCUUGGCG GAAUCAGCGG GGAAAGAAGA CCCUGUUGAG CUUGACUCUA GUCUGGCACG GUGAAGAGAC AUGAGAGGUG UAGAAUAAG UGGGAGGCCC CCGCGCCCUC CCGCCCCCGC GAGGGGCGGG GCGGGGGUGC CGGCCUUGCG GGCCGCCGGU G AAAUACCA CUACUCUUAU CGUUUUUUCA CUGACCCGGU GAGGCGGGGG GGCGAGCCCC GAGGGGCUCU CGCUUCUGGC GC CAAGCGC CCGGCCCCGU CGGUCCGCGC GGGCGGCGGC CGGGCGCGAC CCGCUCCGGG GACAGUGCCA GGUGGGGAGU UUG ACUGGG GCGGUACACC UGUCAAACGG UAACGCAGGU GUCCUAAGGC GAGCUCAGGG AGGACAGAAA CCUCCCGUGG AGCA GAAGG GCAAAAGCUC GCUUGAUCUU GAUUUUCAGU ACGAAUACAG ACCGUGAAAG CGGGGCCUCA CGAUCCUUCU GACCU UUUG GGUUUUAAGC AGGAGGUGUC AGAAAAGUUA CCACAGGGAU AACUGGCUUG UGGCGGCCAA GCGUUCAUAG CGACGU CGC UUUUUGAUCC UUCGAUGUCG GCUCUUCCUA UCAUUGUGAA GCAGAAUUCA CCAAGCGUUG GAUUGUUCAC CCACUAA UA GGGAACGUGA GCUGGGUUUA GACCGUCGUG AGACAGGUUA GUUUUACCCU ACUGAUGAUG UGUUGUUGCC AUGGUAAU C CUGCUCAGUA CGAGAGGAAC CGCAGGUUCA GACAUUUGGU GUAUGUGCUU GGCUGAGGAG CCAAUGGGGC GAAGCUACC AUCUGUGGGA UUAUGACUGA ACGCCUCUAA GUCAGAAUCC CGCCCAGGCG GAACGAUAGC GCCGGAGCCU CGGUUGGCCU CGGAUAGCC GGUCCCCCGC CGUCCCCGCC GGCGGCCCGC GUCGUGCGUC CGCCUCGGCG GCGAGCGGCC CGCCCCCCGC C GCGCGUUG GGACGGGGUC CGGUGCGGAG AGCCCUUCGU CCCGGGAAAC GGGGCGGCCG GAAAGGGGGC CGCCCUCUCG CC CGUCACG CACCGCACGU UCGUGGGGAA CCUGGCGCUA AACCAUUCGU AGACGACCUG CUUCUGGGUC GGGGUUUCGU ACG UAGCAG AGCAGCUCCC UCGCUGCGAU CUAUUGAAAG UCAGCCCUCG ACACAAGGGU UUGU

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分子 #2: 5S ribosomal RNA

分子名称: 5S ribosomal RNA / タイプ: rna / ID: 2 / コピー数: 1
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 38.691914 KDa
配列文字列:
GUCUACGGCC AUACCACCCU GAACGCGCCC GAUCUCGUCU GAUCUCGGAA GCUAAGCAGG GUCGGGCCUG GUUAGUACUU GGAUGGGAG ACCGCCUGGG AAUACCGGGU GCUGUAGGCU U

GENBANK: GENBANK: 4CXE_4

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分子 #3: 5.8S ribosomal RNA

分子名称: 5.8S ribosomal RNA / タイプ: rna / ID: 3 / コピー数: 1
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 50.143648 KDa
配列文字列:
CGACUCUUAG CGGUGGAUCA CUCGGCUCGU GCGUCGAUGA AGAACGCAGC UAGCUGCGAG AAUUAAUGUG AAUUGCAGGA CACAUUGAU CAUCGACACU UCGAACGCAC UUGCGGCCCC GGGUUCCUCC CGGGGCUACG CCUGUCUGAG CGUCGCU

GENBANK: GENBANK: 4CXE_3

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分子 #4: Nascent polypeptide-associated complex subunit alpha N-terminal region

分子名称: Nascent polypeptide-associated complex subunit alpha N-terminal region
タイプ: protein_or_peptide / ID: 4 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 2.526119 KDa
配列文字列:
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) L(UNK)(UNK)(UNK)(UNK)(UNK)P (UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)

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分子 #5: 60S ribosomal protein L8

分子名称: 60S ribosomal protein L8 / タイプ: protein_or_peptide / ID: 5 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 28.088863 KDa
配列文字列: MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAK VVFRDPYRFK KRTELFIAAE GIHTGQFVY CGKKAQLNIG NVLPVGTMPE GTIVCCLEEK PGDRGKLARA SGNYATVISH NPETKKTRVK LPSGSKKVIS S ANRAVVGV ...文字列:
MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAK VVFRDPYRFK KRTELFIAAE GIHTGQFVY CGKKAQLNIG NVLPVGTMPE GTIVCCLEEK PGDRGKLARA SGNYATVISH NPETKKTRVK LPSGSKKVIS S ANRAVVGV VAGGGRIDKP ILKAGRAYHK YKAKRNCWPR VRGVAMNPVE HPFGGGNHQH IGKPSTIRRD APAGRKVGLI AA RRTGRLR GTKTVQEKEN

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分子 #6: Ribosomal protein L3

分子名称: Ribosomal protein L3 / タイプ: protein_or_peptide / ID: 6 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 46.107977 KDa
配列文字列: MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM ...文字列:
MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM RLLPLRQKKA HLMEIQVNGG TVAEKLDWAR ERLEQQVPVS QVFGQDEMID VIGVTKGKGY KGVTSRWHTK KL PRKTHRG LRKVACIGAW HPARVAFSVA RAGQKGYHHR TEINKKIYKI GQGYLIKDGK LIKNNASTDY DLSDKSINPL GGF VHYGEV TNDFVMLKGC VVGTKKRVLT LRKSLLVQTK RRALEKIDLK FIDTTSKFGH GRFQTVEEKK AFMGPLKKDR IAKE EGA

UniProtKB: Large ribosomal subunit protein uL3

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分子 #7: 60S ribosomal protein L4

分子名称: 60S ribosomal protein L4 / タイプ: protein_or_peptide / ID: 7 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 47.727559 KDa
配列文字列: MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV ...文字列:
MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV LLLKKLKAWN DIKKVYASQR MRAGKGKMRN RRRIQRRGPC VIYNEDNGIV KAFRNIPGIT LLNVTKLNIL KL APGGHVG RFCIWTESAF RKLDDLYGTW RKAASLKSNY NLPMHKMLNT DLSRILKSPE IQRALRAPRK KIHRRVLKKN PLK NLRIML KLNPYAKTMR RNTILRQARN HKLRVERAAA ALAAKSDPKE APAKKKPVVG KKVKKPRAVG IKQKKKPVVG RKAA AAKKP AADKKAADKR AGPEDKKPAA

UniProtKB: Large ribosomal subunit protein uL4

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分子 #8: Ribosomal_L18_c domain-containing protein

分子名称: Ribosomal_L18_c domain-containing protein / タイプ: protein_or_peptide / ID: 8 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 34.481828 KDa
配列文字列: MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD ...文字列:
MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD GGLSIPHSTK RFPGYDSESK EFNAEVHRKH IMGQNVADYM RYLMEEDEDA YKKQFSQYIK NNVTPDMMEE MY KKAHAAI RENPVYEKKP KREVKKKRWN RPKMSLAQKK DRVAQKKASF LRAQERAAES

UniProtKB: Large ribosomal subunit protein uL18

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分子 #9: 60S ribosomal protein L6

分子名称: 60S ribosomal protein L6 / タイプ: protein_or_peptide / ID: 9 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 33.028336 KDa
配列文字列: MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGKKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL ...文字列:
MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGKKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL KQLSSGLLLV TGPLSLNRVP LRRTHQKFVI ATSTKIDISG VKIPKHLTDA YFKKKKLRKP RHQEGEIFDT EK EKYEITE QRKVDQKAVD SQILPKIKAV PQLQGYLRSV FALTNGVYPH KLVF

UniProtKB: Large ribosomal subunit protein eL6

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分子 #10: 60S ribosomal protein L7

分子名称: 60S ribosomal protein L7 / タイプ: protein_or_peptide / ID: 10 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 29.201836 KDa
配列文字列: MEGAEEKKKV PAVPETLKKK RRNFAELKIK RLRKKFAQKM LRKARRKLIY EKAKHYHKEY RQMYRTEIRM ARMARKAGNF YVPAEPKLA FVIRIRGING VSPKVRKVLQ LLRLRQIFNG TFVKLNKASI NMLRIVEPYI AWGYPNLKSV NELIYKRGYG K INKKRIAL ...文字列:
MEGAEEKKKV PAVPETLKKK RRNFAELKIK RLRKKFAQKM LRKARRKLIY EKAKHYHKEY RQMYRTEIRM ARMARKAGNF YVPAEPKLA FVIRIRGING VSPKVRKVLQ LLRLRQIFNG TFVKLNKASI NMLRIVEPYI AWGYPNLKSV NELIYKRGYG K INKKRIAL TDNTLIARSL GKYNIICMED LIHEIYTVGK HFKEANNFLW PFKLSSPRGG MKKKTTHFVE GGDAGNREDQ IN RLIRRMN

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分子 #11: 60S ribosomal protein L7a

分子名称: 60S ribosomal protein L7a / タイプ: protein_or_peptide / ID: 11 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 36.221516 KDa
配列文字列: MSSYRLGYCM KEERHNLVLC LWSQSPGILN SKCLWPFTNI HLLVGALPRE GAGGAWGGGR SEQLPTCSTT HHDFTWDKKV VNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQV LDRQTATQLL KLAHKYRPET K QEKKQRLL ...文字列:
MSSYRLGYCM KEERHNLVLC LWSQSPGILN SKCLWPFTNI HLLVGALPRE GAGGAWGGGR SEQLPTCSTT HHDFTWDKKV VNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQV LDRQTATQLL KLAHKYRPET K QEKKQRLL ARAEKKAAGK GDVPTKRPPV LRAGVNTVTT LVENKKAQLV VIAHDVDPIE LVVFLPALCR KMGVPYCILK GK ARLGRLV HRKTCTTVAF TQVNSEDKGA LAKLVEAIRT NYNDRYDEIR RHWGGNVLGP KSVARIAKLE KAKAKELATK LG

UniProtKB: Large ribosomal subunit protein eL8

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分子 #12: 60S ribosomal protein L9

分子名称: 60S ribosomal protein L9 / タイプ: protein_or_peptide / ID: 12 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 21.871418 KDa
配列文字列: MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK ...文字列:
MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK NKDIRKFLDG IYVSEKGTVQ QADE

UniProtKB: Large ribosomal subunit protein uL6

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分子 #13: Ribosomal protein L10

分子名称: Ribosomal protein L10 / タイプ: protein_or_peptide / ID: 13 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 24.643057 KDa
配列文字列: MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS ...文字列:
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS KKWGFTKFNA DEFEDMVAEK RLIPDGCGVK YIPNRGPLDK WRALHS

UniProtKB: Large ribosomal subunit protein uL16

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分子 #14: 60S ribosomal protein L11

分子名称: 60S ribosomal protein L11 / タイプ: protein_or_peptide / ID: 14 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 20.288465 KDa
配列文字列:
MAQDQGEKEN PMRELRIRKL CLNICVGESG DRLTRAAKVL EQLTGQTPVF SKARYTVRSF GIRRNEKIAV HCTVRGAKAE EILEKGLKV REYELRKNNF SDTGNFGFGI QEHIDLGIKY DPSIGIYGLD FYVVLGRPGF SIADKKRRTG CIGAKHRISK E EAMRWFQQ KYDGIILPGK

UniProtKB: Large ribosomal subunit protein uL5

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分子 #15: 60S ribosomal protein L13

分子名称: 60S ribosomal protein L13 / タイプ: protein_or_peptide / ID: 15 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 24.331723 KDa
配列文字列: MAPSRNGMIL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ ARARRIAPRP AAGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKK VARTIGISVD PRRRNKSTES LQANVQRLKE YRSKLVLFPR KPSAPKKGDS SAEELKLATQ LTGPVMPIRN V FKKEKARV ...文字列:
MAPSRNGMIL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ ARARRIAPRP AAGPIRPIVR CPTVRYHTKV RAGRGFSLEE LRVAGIHKK VARTIGISVD PRRRNKSTES LQANVQRLKE YRSKLVLFPR KPSAPKKGDS SAEELKLATQ LTGPVMPIRN V FKKEKARV ITEEEKNFKA FASLRMARAN ARLFGIRAKR AKEAAEQDVE KKK

UniProtKB: Large ribosomal subunit protein eL13

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分子 #16: 60S ribosomal protein L14

分子名称: 60S ribosomal protein L14 / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 23.870549 KDa
配列文字列: MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG ...文字列:
MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG KKAAAQKAPA QKAPAQKAAG QKAAQPPKAQ KGQKPPAQKA PAPKASGKKA

UniProtKB: Large ribosomal subunit protein eL14

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分子 #17: Ribosomal protein L15

分子名称: Ribosomal protein L15 / タイプ: protein_or_peptide / ID: 17 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 24.207285 KDa
配列文字列: MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG ...文字列:
MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG RKSRGLGKGH KFHHTIGGSR RAAWRRRNTL QLHRYR

UniProtKB: Large ribosomal subunit protein eL15

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分子 #18: 60S ribosomal protein L13a

分子名称: 60S ribosomal protein L13a / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 23.533299 KDa
配列文字列: MAEGQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLP HKTKRGQAAL DRLKVFDGIP PPYDKKKRMV VPAALKVVRL KPTRKFAYLG RLAHEVGWKY QAVTATLEEK R KEKAKIHY ...文字列:
MAEGQVLVLD GRGHLLGRLA AIVAKQVLLG RKVVVVRCEG INISGNFYRN KLKYLAFLRK RMNTNPSRGP YHFRAPSRIF WRTVRGMLP HKTKRGQAAL DRLKVFDGIP PPYDKKKRMV VPAALKVVRL KPTRKFAYLG RLAHEVGWKY QAVTATLEEK R KEKAKIHY RKKKQLMRLR KQAEKNVEKK ISKFTDVLKT HGLLV

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分子 #19: 60S ribosomal protein L17

分子名称: 60S ribosomal protein L17 / タイプ: protein_or_peptide / ID: 19 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 21.444221 KDa
配列文字列:
MVRYSLDPEN PTKSCKSRGS NLRVHFKNTR ETAQAIKGMH IRKATKYLKD VTLKKQCVPF RRYNGGVGRC AQAKQWGWTQ GRWPKKSAE FLLHMLKNAE SNAELKGLDV DSLVIEHIQV NKAPKMRRRT YRAHGRINPY MSSPCHIEMI LTEKEQIVPK P EEEVAQKK KISQKKLKKQ KLMARE

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分子 #20: Ribosomal protein L18

分子名称: Ribosomal protein L18 / タイプ: protein_or_peptide / ID: 20 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 21.568492 KDa
配列文字列:
GVDIRHNKDR KVRRKEPKSQ DIYLRLLVKL YRFLARRTNS TFNQVVLKRL FMSRTNRPPL SLSRMIRKMK LPGRENKTAV VVGTVTDDV RVQEVPKLKV CALRVTSRAR SRILKAGGKI LTFDQLALDS PKGRGTVLLS GPRKGREVYR HFGKAPGTPH S HTKPYVRS KGRKFERARG RRASRGYKN

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分子 #21: 60S ribosomal protein L19

分子名称: 60S ribosomal protein L19 / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 23.535281 KDa
配列文字列: MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ...文字列:
MSMLRLQKRL ASSVLRCGKK KVWLDPNETN EIANANSRQQ IRKLIKDGLI IRKPVTVHSR ARCRKNTLAR RKGRHMGIGK RKGTANARM PEKVTWMRRM RILRRLLRRY RESKKIDRHM YHSLYLKVKG NVFKNKRILM EHIHKLKADK ARKKLLADQA E ARRSKTKE ARKRREERLQ AKKEEIIKTL SKEEETKK

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分子 #22: 60S ribosomal protein L18a

分子名称: 60S ribosomal protein L18a / タイプ: protein_or_peptide / ID: 22 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 20.827561 KDa
配列文字列:
MKASGTLREY KVVGRCLPTP KCRTPPLYRM RIFAPNHVVA KSRFWYFVSQ LKKMKKSSGE IVYCGQVFEK SPLRVKNFGI WLRYDSRSG THNMYREYRD LTTAGAVTQC YRDMGARHRA RAHSIQIMKV EEIAASKCRR PAVKQFHDSK IKFPLPHRVL R RQHKPRFT TKRPNTFF

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分子 #23: 60S ribosomal protein L21

分子名称: 60S ribosomal protein L21 / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 18.609988 KDa
配列文字列:
MTNTKGKRRG TRYMFSRPFR KHGVVPLATY MRIYKKGDIV DIKGMGTVQK GMPHKCYHGK TGRVYNVTQH AVGIVVNKQV KGKILAKRI NVRIEHIKHS KSRDSFLKRV KENDQKKKEA KEKGTWVQLK RQPAPPREAH FVRTNGKEPE LLEPIPYEFM A

UniProtKB: Large ribosomal subunit protein eL21

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分子 #24: 60S ribosomal protein L22

分子名称: 60S ribosomal protein L22 / タイプ: protein_or_peptide / ID: 24 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 14.813015 KDa
配列文字列:
MAPVKKLVAK GGKKKKQLLK FTLDCTHPVE DGIMDAANFE QFLQERIKVN GKAGNLGGGV VSLERSKSKI TVTSEVPFSK RYLKYLTKK YLKKNNLRDW LRVVANTKES YELRYFQINQ DEEEEEEED

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分子 #25: 60S ribosomal protein L23

分子名称: 60S ribosomal protein L23 / タイプ: protein_or_peptide / ID: 25 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 14.892505 KDa
配列文字列:
MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM VMATVKKGKP ELRKKVHPAV VIRQRKSYR RKDGVFLYFE DNAGVIVNNK GEMKGSAITG PVAKECADLW PRIASNAGSI A

UniProtKB: Large ribosomal subunit protein uL14

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分子 #26: Ribosomal protein L24

分子名称: Ribosomal protein L24 / タイプ: protein_or_peptide / ID: 26 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 17.825111 KDa
配列文字列:
MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN WTVLYRRKHK KGQSEEIQKK RTRRAVKFQR AITGASLAD IMAKRNQKPE VRKAQREQAI RAAKEAKKAK QASKKTAMAA AKAPTKAAPK QKIVKPVKVS APRVGGKR

UniProtKB: Large ribosomal subunit protein eL24

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分子 #27: Ribosomal_L23eN domain-containing protein

分子名称: Ribosomal_L23eN domain-containing protein / タイプ: protein_or_peptide / ID: 27 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 17.768246 KDa
配列文字列:
MAPKAKKEAP APPKVEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY PRKSAPRRNK LDHYAIIKFP LTTESAMKK IEDNNTLVFI VDVKANKHQI KQAVKKLYDI DVAKVNTLIR PDGEKKAYVR LAPDYDALDV ANKIGII

UniProtKB: Large ribosomal subunit protein uL23

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分子 #28: Ribosomal protein L26

分子名称: Ribosomal protein L26 / タイプ: protein_or_peptide / ID: 28 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 17.303363 KDa
配列文字列:
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREK ANGTTVHVGI HPSKVVITRL KLDKDRKKIL ERKAKSRQVG KEKGKYKEET IEKMQE

UniProtKB: Large ribosomal subunit protein uL24

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分子 #29: 60S ribosomal protein L27

分子名称: 60S ribosomal protein L27 / タイプ: protein_or_peptide / ID: 29 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 15.835831 KDa
配列文字列:
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDI PLDKTVVNKD VFRDPALKRK ARREAKVKFE ERYKTGKNKW FFQKLRF

UniProtKB: Large ribosomal subunit protein eL27

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分子 #30: 60S ribosomal protein L27a

分子名称: 60S ribosomal protein L27a / タイプ: protein_or_peptide / ID: 30 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 16.620561 KDa
配列文字列:
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGMHH HRINFDKYHP GYFGKVGMRH YHLKRNQSFC PTVNLDKLWT LVSEQTRVN AAKNKTGAAP IIDVVRSGYY KVLGKGKLPK QPVIVKAKFF SRRAEEKIKG VGGACVLVA

UniProtKB: Large ribosomal subunit protein uL15

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分子 #31: 60S ribosomal protein L29

分子名称: 60S ribosomal protein L29 / タイプ: protein_or_peptide / ID: 31 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 24.931625 KDa
配列文字列: MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALVKPKE VKPTIPKGV SRKLHRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGKAQA E TKPKAQAE ...文字列:
MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALVKPKE VKPTIPKGV SRKLHRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGKAQA E TKPKAQAE TKPKAQAQAK PKAQAQGKPK AQAQGKPKAQ AQAKPKAQAQ AKPKAQAQTK PKAQATPA

UniProtKB: Large ribosomal subunit protein eL29

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分子 #32: 60S ribosomal protein L30

分子名称: 60S ribosomal protein L30 / タイプ: protein_or_peptide / ID: 32 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 12.807065 KDa
配列文字列:
MVAAKKTKKS LESINSRLQL VMKSGKYVLG YKQSLKMIRQ GKAKLVILAN NCPALRKSEI EYYAMLAKTG VHHYSGNNIE LGTACGKYY RVCTLSIIDP GDSDIIRSMP EQTGEK

UniProtKB: Large ribosomal subunit protein eL30

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分子 #33: 60S ribosomal protein L31

分子名称: 60S ribosomal protein L31 / タイプ: protein_or_peptide / ID: 33 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 14.494938 KDa
配列文字列:
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLS RKRNEDEDSP NKLYTLVTYV PVTTFKNLQT VNVDEN

UniProtKB: Large ribosomal subunit protein eL31

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分子 #34: Ribosomal protein L32

分子名称: Ribosomal protein L32 / タイプ: protein_or_peptide / ID: 34 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 15.898932 KDa
配列文字列:
MAALRPLVKP KIVKKRTKKF IRHQSDRYVK IKRNWRKPRG IDNRVRRRFK GQILMPNIGY GSNKKTKHML PSGFRKFLVH NVKELEVLL MCNKSYCAEI AHNVSSKNRK AIVERAAQLA IRVTNPNARL RSEENE

UniProtKB: Large ribosomal subunit protein eL32

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分子 #35: 60S ribosomal protein L35a

分子名称: 60S ribosomal protein L35a / タイプ: protein_or_peptide / ID: 35 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 12.580809 KDa
配列文字列:
MSGRLWCKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFR SNLPAKAIGH RIRVMLYPSR I

UniProtKB: Large ribosomal subunit protein eL33

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分子 #36: 60S ribosomal protein L34

分子名称: 60S ribosomal protein L34 / タイプ: protein_or_peptide / ID: 36 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 13.196894 KDa
配列文字列:
MVQRLTYRRR LSYNTASNKT RLSRTPGNRI VYLYTKKVGK APKSACGVCP GRLRGVRAVR PKVLMRLSKT KKHVSRAYGG SMCAKCVRD RIKRAFLIEE QKIVVKVLKA QAQSQKA

UniProtKB: Large ribosomal subunit protein eL34

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分子 #37: 60S ribosomal protein L35

分子名称: 60S ribosomal protein L35 / タイプ: protein_or_peptide / ID: 37 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 14.435403 KDa
配列文字列:
AKIKARDLRG KKKEELLKQL DDLKVELSQL RVAKVTGGAA SKLSKIRVVR KSIARVLTVI NQTQKENLRK FYKGKKYKPL DLRPKKTRA MRRRLNKHEE SLKTKKQQRK ERLYPLRKYA VKA

UniProtKB: Large ribosomal subunit protein uL29

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分子 #38: 60S ribosomal protein L36

分子名称: 60S ribosomal protein L36 / タイプ: protein_or_peptide / ID: 38 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 12.263834 KDa
配列文字列:
MALRYPMAVG LNKGHKVTKN VSKPRHSRRR GRLTKHTKFV RDMIREVCGF APYERRAMEL LKVSKDKRAL KFIKKRVGTH IRAKRKREE LSSVLAAMRK AAAKKD

UniProtKB: Large ribosomal subunit protein eL36

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分子 #39: Ribosomal protein L37

分子名称: Ribosomal protein L37 / タイプ: protein_or_peptide / ID: 39 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 11.111032 KDa
配列文字列:
MTKGTSSFGK RRNKTHTLCR RCGSKAYHLQ KSTCGKCGYP AKRKRKYNWS AKAKRRNTTG TGRMRHLKIV YRRFRHGFRE GTTPKPKRA AVAASSSS

UniProtKB: Large ribosomal subunit protein eL37

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分子 #40: 60S ribosomal protein L38

分子名称: 60S ribosomal protein L38 / タイプ: protein_or_peptide / ID: 40 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 8.238948 KDa
配列文字列:
MPRKIEEIKD FLLTARRKDA KSVKIKKNKD NVKFKVRCSR YLYTLVITDK EKAEKLKQSL PPGLAVKELK

UniProtKB: Large ribosomal subunit protein eL38

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分子 #41: 60S ribosomal protein L39-like

分子名称: 60S ribosomal protein L39-like / タイプ: protein_or_peptide / ID: 41 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 6.455775 KDa
配列文字列:
MSSHKTFRIK RFLAKKQKQN RPIPQWIWMK TGNKIRYNSK RRHWRRTKLG L

UniProtKB: Large ribosomal subunit protein eL39

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分子 #42: Ubiquitin-60S ribosomal protein L40

分子名称: Ubiquitin-60S ribosomal protein L40 / タイプ: protein_or_peptide / ID: 42 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 11.69979 KDa
配列文字列:
MGDPESGGCI PPDQQRLIFA GKQLEDGRTL SDYNIQKEST LHLVLRLRGG IIEPSLRQLA QKYNCDKMIC RKCYARLHPR AVNCRKKKC GHTNNLRPKK KVK

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分子 #43: 60S ribosomal protein L41

分子名称: 60S ribosomal protein L41 / タイプ: protein_or_peptide / ID: 43 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 3.473451 KDa
配列文字列:
MRAKWRKKRM RRLKRKRRKM RQRSK

UniProtKB: Small ribosomal subunit protein eS32

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分子 #44: 60S ribosomal protein L36a-like

分子名称: 60S ribosomal protein L36a-like / タイプ: protein_or_peptide / ID: 44 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 12.476973 KDa
配列文字列:
MVNVPKTRRT FCKKCGKHQP HKVTQYKKGK DSLYAQGKRR YDRKQSGYGG QTKPIFRKKA KTTKKIVLRL ECVEPNCRSK RMLAIKRCK HFELGGDKKR KGQVIQF

UniProtKB: Large ribosomal subunit protein eL42

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分子 #45: 60S ribosomal protein L37a

分子名称: 60S ribosomal protein L37a / タイプ: protein_or_peptide / ID: 45 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 10.29935 KDa
配列文字列:
MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR AVGIWHCGSC MKTVAGGAWT YNTTSAVTVK SAIRRLKEL KDQ

UniProtKB: Large ribosomal subunit protein eL43

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分子 #46: 60S ribosomal protein L28

分子名称: 60S ribosomal protein L28 / タイプ: protein_or_peptide / ID: 46 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 15.783614 KDa
配列文字列:
MSAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG VEPAADGKGV VVVMKRRSGQ RKPATSYVRT TINKNARAT LSSIRHMIRK NKYHPDLRMA AIRRASAILR SQKPVMVKRK RTRPTKSS

UniProtKB: Large ribosomal subunit protein eL28

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分子 #47: 60S acidic ribosomal protein P0

分子名称: 60S acidic ribosomal protein P0 / タイプ: protein_or_peptide / ID: 47 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 34.380504 KDa
配列文字列: MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK AVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIRGNVGFV FTKEDLTEIR DMLLANKVPA AARAGAIAPC EVTVPAQNTG LGPEKTSFFQ ALGITTKISR GTIEILSDVQ L IKTGDKVG ...文字列:
MPREDRATWK SNYFLKIIQL LDDYPKCFIV GADNVGSKQM QQIRMSLRGK AVVLMGKNTM MRKAIRGHLE NNPALEKLLP HIRGNVGFV FTKEDLTEIR DMLLANKVPA AARAGAIAPC EVTVPAQNTG LGPEKTSFFQ ALGITTKISR GTIEILSDVQ L IKTGDKVG ASEATLLNML NISPFSFGLI IQQVFDNGSI YNPEVLDITE DTLHSRFLEG VRNVASVCLQ IGYPTVASVP HS IINGYKR VLALSVETEY TFPLAEKVKA FLADPSAFVA AAPVAAASTA APAAAAAAPA KVEAKEESEE SDEDMGFGLF D

UniProtKB: Large ribosomal subunit protein uL10

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分子 #48: 60S ribosomal protein L12

分子名称: 60S ribosomal protein L12 / タイプ: protein_or_peptide / ID: 48 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: rabbit (ウサギ)
分子量理論値: 17.847619 KDa
配列文字列:
MPPKFDPNEI KVVYLRCTGG EVGATSALAP KIGPLGLSPK KVGDDIAKAT GDWKGLRITV KLTIQNRQAQ IEVVPSASAL IIKALKEPP RDRKKQKNIK HSGNITFDEI VNIARQMRHR SLARELSGTI KEILGTAQSV GCNVDGRHPH DIIDDINSGA V ECPAS

UniProtKB: Large ribosomal subunit protein uL11

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分子 #49: S phase cyclin A-associated protein in the endoplasmic reticulum

分子名称: S phase cyclin A-associated protein in the endoplasmic reticulum
タイプ: protein_or_peptide / ID: 49
詳細: First 11 N-terminal residues correspond to a FLAG-tag
コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 159.795547 KDa
組換発現生物種: Homo sapiens (ヒト)
配列文字列: MDYKDDDDKG SMMASFQRSN SHDKVRRIVA EEGRTARNLI AWSVPLESKD DDGKPKCQTG GKSKRTIQGT HKTTKQSTAV DCKITSSTT GDKHFDKSPT KTRHPRKIDL RARYWAFLFD NLRRAVDEIY VTCESDQSVV ECKEVLMMLD NYVRDFKALI D WIQLQEKL ...文字列:
MDYKDDDDKG SMMASFQRSN SHDKVRRIVA EEGRTARNLI AWSVPLESKD DDGKPKCQTG GKSKRTIQGT HKTTKQSTAV DCKITSSTT GDKHFDKSPT KTRHPRKIDL RARYWAFLFD NLRRAVDEIY VTCESDQSVV ECKEVLMMLD NYVRDFKALI D WIQLQEKL EKTDAQSRPT SLAWEVKKMS PGRHVIPSPS TDRINVTSNA RRSLNFGGST GTVPAPRLAP TGVSWADKVK AH HTGSTAS SEITPAQSCP PMTVQKASRK NERKDAEGWE TVQRGRPIRS RSTAVMPKVS LATEATRSKD DSDKENVCLL PDE SIQKGQ FVGDGTSNTI ESHPKDSLHS CDHPLAEKTQ FTVSTLDDVK NSGSIRDNYV RTSEISAVHI DTECVSVMLQ AGTP PLQVN EEKFPAEKAR IENEMDPSDI SNSMAEVLAK KEELADRLEK ANEEAIASAI AEEEQLTREI EAEENNDINI ETDND SDFS ASMGSGSVSF CGMSMDWNDV LADYEARESW RQNTSWGDIV EEEPARPPGH GIHMHEKLSS PSRKRTIAES KKKHEE KQM KAQQLREKLR EEKTLKLQKL LEREKDVRKW KEELLDQRRR MMEEKLLHAE FKREVQLQAI VKKAQEEEAK VNEIAFI NT LEAQNKRHDV LSKLKEYEQR LNELQEERQR RQEEKQARDE AVQERKRALE AERQARVEEL LMKRKEQEAR IEQQRQEK E KAREDAARER ARDREERLAA LTAAQQEAME ELQKKIQLKH DESIRRHMEQ IEQRKEKAAE LSSGRHANTD YAPKLTPYE RKKQCSLCNV LISSEVYLFS HVKGRKHQQA VRENTSIQGR ELSDEEVEHL SLKKYIIDIV VESTAPAEAL KDGEERQKNK KKAKKIKAR MNFRAKEYES LMETKNSGSD SPYKAKLQRL AKDLLKQVQV QDSGSWANNK VSALDRTLGE ITRILEKENV A DQIAFQAA GGLTALEHIL QAVVPATNVN TVLRIPPKSL CNAINVYNLT CNNCSENCSD VLFSNKITFL MDLLIHQLTV YV PDENNTI LGRNTNKQVF EGLTTGLLKV SAVVLGCLIA NRPDGNCQPA TPKIPTQEMK NKPSQGDPFN NRVQDLISYV VNM GLIDKL CACFLSVQGP VDENPKMAIF LQHAAGLLHA MCTLCFAVTG RSYSIFDNNR QDPTGLTAAL QATDLAGVLH MLYC VLFHG TILDPSTASP KENYTQNTIQ VAIQSLRFFN SFAALHLPAF QSIVGAEGLS LAFRHMASSL LGHCSQVSCE SLLHE VIVC VGYFTVNHPD NQVIVQSGRH PTVLQKLCQL PFQYFSDPRL IKVLFPSLIA ACYNNHQNKI ILEQEMSCVL LATFIQ DLA QTPGQAENQP YQPKGKCLGS QDYLELANRF PQQAWEEARQ FFLKKEKK

UniProtKB: S phase cyclin A-associated protein in the endoplasmic reticulum

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分子 #50: Tetratricopeptide repeat protein 5

分子名称: Tetratricopeptide repeat protein 5 / タイプ: protein_or_peptide / ID: 50
詳細: The first 49 N-terminal residues correspond to a 6x His and a twin strep tag.
コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 54.176863 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MGHHHHHHEN LYFQGSAWSH PQFEKGGGSG GGSGGSAWSH PQFEKGSSGM MADEEEEVKP ILQKLQELVD QLYSFRDCYF ETHSVEDAG RKQQDVQKEM EKTLQQMEEV VGSVQGKAQV LMLTGKALNV TPDYSPKAEE LLSKAVKLEP ELVEAWNQLG E VYWKKGDV ...文字列:
MGHHHHHHEN LYFQGSAWSH PQFEKGGGSG GGSGGSAWSH PQFEKGSSGM MADEEEEVKP ILQKLQELVD QLYSFRDCYF ETHSVEDAG RKQQDVQKEM EKTLQQMEEV VGSVQGKAQV LMLTGKALNV TPDYSPKAEE LLSKAVKLEP ELVEAWNQLG E VYWKKGDV AAAHTCFSGA LTHCRNKVSL QNLSMVLRQL RTDTEDEHSH HVMDSVRQAK LAVQMDVHDG RSWYILGNSY LS LYFSTGQ NPKISQQALS AYAQAEKVDR KASSNPDLHL NRATLHKYEE SYGEALEGFS RAAALDPAWP EPRQREQQLL EFL DRLTSL LESKGKVKTK KLQSMLGSLR PAHLGPCSDG HYQSASGQKV TLELKPLSTL QPGVNSGAVI LGKVVFSLTT EEKV PFTFG LVDSDGPCYA VMVYNIVQSW GVLIGDSVAI PEPNLRLHRI QHKGKDYSFS SVRVETPLLL VVNGKPQGSS SQAVA TVAS RPQCE

UniProtKB: Tetratricopeptide repeat protein 5

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分子 #51: Tubulin beta chain

分子名称: Tubulin beta chain / タイプ: protein_or_peptide / ID: 51 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 7.163992 KDa
組換発現生物種: Oryctolagus cuniculus (ウサギ)
配列文字列:
MREIVHIQAG QCGNQIGAKF WEVISDEHGI DPTGTYHGDS DLQLDRISVY YNEATGGKYV MKLV

UniProtKB: Tubulin beta chain

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分子 #52: MAGNESIUM ION

分子名称: MAGNESIUM ION / タイプ: ligand / ID: 52 / コピー数: 214 / 式: MG
分子量理論値: 24.305 Da

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分子 #53: ZINC ION

分子名称: ZINC ION / タイプ: ligand / ID: 53 / コピー数: 5 / 式: ZN
分子量理論値: 65.409 Da

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態particle

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試料調製

緩衝液pH: 7.4
グリッドモデル: UltrAuFoil R1.2/1.3 / 材質: GOLD / 支持フィルム - 材質: GRAPHENE OXIDE / 支持フィルム - トポロジー: CONTINUOUS / 前処理 - タイプ: GLOW DISCHARGE
凍結凍結剤: ETHANE / チャンバー内湿度: 100 % / チャンバー内温度: 277 K / 装置: FEI VITROBOT MARK IV

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電子顕微鏡法

顕微鏡FEI TITAN KRIOS
撮影フィルム・検出器のモデル: GATAN K3 (6k x 4k) / 撮影したグリッド数: 1 / 実像数: 20932 / 平均露光時間: 1.8 sec. / 平均電子線量: 44.7 e/Å2
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系C2レンズ絞り径: 70.0 µm / 照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELD / Cs: 2.7 mm / 最大 デフォーカス（公称値）: 2.7 µm / 最小 デフォーカス（公称値）: 1.2 µm / 倍率（公称値）: 105000
試料ステージ試料ホルダーモデル: FEI TITAN KRIOS AUTOGRID HOLDER
ホルダー冷却材: NITROGEN
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

粒子像選択選択した数: 1227269
初期モデルモデルのタイプ: EMDB MAP
EMDB ID:

10181

最終 再構成解像度のタイプ: BY AUTHOR / 解像度: 2.8 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 18949
初期 角度割当タイプ: MAXIMUM LIKELIHOOD / ソフトウェア - 名称: RELION (ver. 4.0)
最終 角度割当タイプ: MAXIMUM LIKELIHOOD / ソフトウェア - 名称: RELION (ver. 4.0)
最終 3次元分類ソフトウェア - 名称: RELION (ver. 4.0)
FSC曲線 (解像度の算出)

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbjlc1.pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る