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- EMDB-12303: Mammalian ribosome nascent chain complex with SRP and SRP recepto... -

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基本情報

登録情報
データベース: EMDB / ID: EMD-12303
タイトルMammalian ribosome nascent chain complex with SRP and SRP receptor in early state A
マップデータcomplex of RNC with SRPG226E and SRP receptor
試料
  • 複合体: ribosome nascent chain complex with SRP and SRP receptor
    • 複合体: ribosomal proteins
      • RNA: x 3種
      • タンパク質・ペプチド: x 42種
    • 複合体: SRP
      • RNA: x 1種
      • タンパク質・ペプチド: x 8種
    • 複合体: Signal Sequence
      • タンパク質・ペプチド: x 1種
  • リガンド: x 4種
キーワードSignal recognition particle / protein targeting to the ER membrane / RIBOSOME
機能・相同性
機能・相同性情報


signal recognition particle receptor complex / SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition / signal recognition particle, endoplasmic reticulum targeting / Translesion synthesis by REV1 / Recognition of DNA damage by PCNA-containing replication complex / Translesion Synthesis by POLH / Downregulation of ERBB4 signaling / Spry regulation of FGF signaling / Downregulation of ERBB2:ERBB3 signaling / NOD1/2 Signaling Pathway ...signal recognition particle receptor complex / SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition / signal recognition particle, endoplasmic reticulum targeting / Translesion synthesis by REV1 / Recognition of DNA damage by PCNA-containing replication complex / Translesion Synthesis by POLH / Downregulation of ERBB4 signaling / Spry regulation of FGF signaling / Downregulation of ERBB2:ERBB3 signaling / NOD1/2 Signaling Pathway / APC/C:Cdc20 mediated degradation of Cyclin B / SCF-beta-TrCP mediated degradation of Emi1 / APC-Cdc20 mediated degradation of Nek2A / EGFR downregulation / TCF dependent signaling in response to WNT / NRIF signals cell death from the nucleus / p75NTR recruits signalling complexes / NF-kB is activated and signals survival / Activated NOTCH1 Transmits Signal to the Nucleus / Downregulation of TGF-beta receptor signaling / TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) / Downregulation of SMAD2/3:SMAD4 transcriptional activity / SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription / Senescence-Associated Secretory Phenotype (SASP) / Regulation of innate immune responses to cytosolic DNA / activated TAK1 mediates p38 MAPK activation / JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 / Regulation of FZD by ubiquitination / PINK1-PRKN Mediated Mitophagy / N-glycan trimming in the ER and Calnexin/Calreticulin cycle / Regulation of TNFR1 signaling / TNFR1-induced NF-kappa-B signaling pathway / Translesion synthesis by POLK / Translesion synthesis by POLI / Regulation of necroptotic cell death / MAP3K8 (TPL2)-dependent MAPK1/3 activation / HDR through Homologous Recombination (HRR) / Josephin domain DUBs / Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks / Processing of DNA double-strand break ends / Formation of Incision Complex in GG-NER / Gap-filling DNA repair synthesis and ligation in GG-NER / Dual Incision in GG-NER / Fanconi Anemia Pathway / Regulation of TP53 Activity through Phosphorylation / Regulation of TP53 Degradation / Regulation of TP53 Activity through Methylation / Negative regulation of MET activity / Cyclin D associated events in G1 / PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 / Downregulation of ERBB2 signaling / E3 ubiquitin ligases ubiquitinate target proteins / Regulation of PTEN localization / ER Quality Control Compartment (ERQC) / Regulation of expression of SLITs and ROBOs / Interferon alpha/beta signaling / Endosomal Sorting Complex Required For Transport (ESCRT) / Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) / IKK complex recruitment mediated by RIP1 / IRAK2 mediated activation of TAK1 complex / TRAF6-mediated induction of TAK1 complex within TLR4 complex / Alpha-protein kinase 1 signaling pathway / RAS processing / Pexophagy / Inactivation of CSF3 (G-CSF) signaling / Negative regulation of FLT3 / Regulation of BACH1 activity / IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation / Regulation of NF-kappa B signaling / Termination of translesion DNA synthesis / Ovarian tumor domain proteases / Negative regulators of DDX58/IFIH1 signaling / Negative regulation of FGFR1 signaling / Negative regulation of FGFR2 signaling / Negative regulation of FGFR3 signaling / Negative regulation of FGFR4 signaling / Negative regulation of MAPK pathway / Synthesis of active ubiquitin: roles of E1 and E2 enzymes / Iron uptake and transport / Deactivation of the beta-catenin transactivating complex / Metalloprotease DUBs / Formation of TC-NER Pre-Incision Complex / Dual incision in TC-NER / Gap-filling DNA repair synthesis and ligation in TC-NER / Major pathway of rRNA processing in the nucleolus and cytosol / GTP hydrolysis and joining of the 60S ribosomal subunit / DNA Damage Recognition in GG-NER / Activation of NF-kappaB in B cells / Autodegradation of Cdh1 by Cdh1:APC/C / APC/C:Cdc20 mediated degradation of Securin / APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 / Cdc20:Phospho-APC/C mediated degradation of Cyclin A / SCF(Skp2)-mediated degradation of p27/p21 / FCERI mediated NF-kB activation / Autodegradation of the E3 ubiquitin ligase COP1 / Asymmetric localization of PCP proteins / Degradation of AXIN / Degradation of DVL / Hedgehog ligand biogenesis / Dectin-1 mediated noncanonical NF-kB signaling
類似検索 - 分子機能
Signal recognition particle receptor, alpha subunit, N-terminal / Signal recognition particle, alpha subunit, N-terminal / Signal recognition particle, SRP72 subunit, RNA-binding / Signal recognition particle receptor, beta subunit / Signal recognition particle, SRP72 subunit / Putative TPR-like repeat / SRP72 RNA-binding domain / Signal recognition particle receptor beta subunit / Putative TPR-like repeat / Signal recognition particle, SRP9 subunit ...Signal recognition particle receptor, alpha subunit, N-terminal / Signal recognition particle, alpha subunit, N-terminal / Signal recognition particle, SRP72 subunit, RNA-binding / Signal recognition particle receptor, beta subunit / Signal recognition particle, SRP72 subunit / Putative TPR-like repeat / SRP72 RNA-binding domain / Signal recognition particle receptor beta subunit / Putative TPR-like repeat / Signal recognition particle, SRP9 subunit / SRP9 domain / Signal recognition particle SRP9 / Signal recognition particle 9 kDa protein (SRP9) / Signal recognition particle, SRP14 subunit / Signal recognition particle, SRP9/SRP14 subunit / Signal recognition particle 14kD protein / Signal recognition particle subunit SRP68 / Signal recognition particle subunit SRP68, RNA-binding domain / SRP68, N-terminal domain superfamily / RNA-binding signal recognition particle 68 / Signal recognition particle, SRP54 subunit, eukaryotic / Signal recognition particle, SRP19 subunit / Signal recognition particle, subunit SRP19-like superfamily / SRP19 protein / SRP/SRP receptor, N-terminal / Signal recognition particle, SRP54 subunit / Signal recognition particle, SRP54 subunit, M-domain / Signal recognition particle, SRP54 subunit, M-domain superfamily / Signal peptide binding domain / SRP54-type proteins GTP-binding domain signature. / Signal recognition particle SRP54, helical bundle / Signal recognition particle SRP54, N-terminal domain superfamily / SRP54-type protein, helical bundle domain / SRP54-type protein, helical bundle domain / Signal recognition particle, SRP54 subunit, GTPase domain / SRP54-type protein, GTPase domain / SRP54-type protein, GTPase domain / Longin-like domain superfamily / Ribosomal protein L6, N-terminal / Ribosomal protein L6, N-terminal domain / Tetratricopeptide repeat / Ribosomal protein L28e / Ribosomal L15/L27a, N-terminal / Ribosomal protein L23 / Ribosomal L28e/Mak16 / Ribosomal L28e protein family / Ribosomal protein L41 / Ribosomal protein L41 / metallochaperone-like domain / TRASH domain / Ribosomal protein L29e / Ribosomal L29e protein family / Ribosomal protein L22e / Ribosomal protein L22e superfamily / Ribosomal L22e protein family / Ribosomal protein L27e, conserved site / Ribosomal protein L27e signature. / Ribosomal protein L44e signature. / Ribosomal protein L10e, conserved site / Ribosomal protein L10e signature. / Ribosomal protein L10e / Ribosomal protein L19, eukaryotic / : / Ribosomal protein L24e, conserved site / Ribosomal protein L24e signature. / Ribosomal protein L44e / Ribosomal protein L19/L19e conserved site / Ribosomal protein L44 / Ribosomal protein L19e signature. / Ribosomal protein L34e, conserved site / Ribosomal protein L34e signature. / Ribosomal protein L5 eukaryotic, C-terminal / Ribosomal L18 C-terminal region / Ribosomal protein L6e signature. / Ribosomal L40e family / Ribosomal_L40e / Ribosomal protein L40e / Ribosomal protein L40e superfamily / Eukaryotic Ribosomal Protein L27, KOW domain / Ribosomal protein L23/L25, N-terminal / Ribosomal protein L23, N-terminal domain / Ribosomal protein 60S L18 and 50S L18e / Ribosomal protein L27e / Ribosomal protein L27e superfamily / Ribosomal L27e protein family / Ribosomal protein L39e, conserved site / Ribosomal protein L39e signature. / Ribosomal protein L34Ae / Ribosomal protein L34e / 60S ribosomal protein L19 / Ribosomal protein L35Ae, conserved site / Ribosomal protein L35Ae signature. / Ribosomal protein L18/L18-A/B/e, conserved site / Ribosomal protein L18e signature. / 60S ribosomal protein L35 / Ribosomal Protein L6, KOW domain / Ribosomal protein L7A/L8 / Ribosomal protein L6e / TPR repeat region circular profile. / 60S ribosomal protein L6E
類似検索 - ドメイン・相同性
Small ribosomal subunit protein eS32 / Large ribosomal subunit protein eL42 / Large ribosomal subunit protein uL16 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 / Large ribosomal subunit protein eL6 ...Small ribosomal subunit protein eS32 / Large ribosomal subunit protein eL42 / Large ribosomal subunit protein uL16 / Large ribosomal subunit protein eL24 / Large ribosomal subunit protein uL23 / Large ribosomal subunit protein eL33 / Large ribosomal subunit protein eL31 / Large ribosomal subunit protein eL21 / Large ribosomal subunit protein uL29 / Large ribosomal subunit protein eL6 / Large ribosomal subunit protein uL15 / Large ribosomal subunit protein uL24 / Large ribosomal subunit protein eL8 / Large ribosomal subunit protein uL30 / Large ribosomal subunit protein uL4 / Large ribosomal subunit protein uL6 / Large ribosomal subunit protein eL43 / Large ribosomal subunit protein uL18 / Large ribosomal subunit protein eL39 / Large ribosomal subunit protein eL15 / Large ribosomal subunit protein uL14 / Large ribosomal subunit protein uL3 / Large ribosomal subunit protein eL29 / Uncharacterized protein / Large ribosomal subunit protein eL22 / Large ribosomal subunit protein uL5 / Large ribosomal subunit protein eL32 / Large ribosomal subunit protein uL22 / Large ribosomal subunit protein uL15/eL18 domain-containing protein / Large ribosomal subunit protein eL27 / Large ribosomal subunit protein eL28 / Large ribosomal subunit protein eL34 / Signal recognition particle subunit SRP72 / Signal recognition particle receptor subunit alpha / Signal recognition particle 19 kDa protein / Signal recognition particle 14 kDa protein / Signal recognition particle 9 kDa protein / Signal recognition particle subunit SRP54 / Ubiquitin-ribosomal protein eL40 fusion protein / Large ribosomal subunit protein eL19 / Signal recognition particle subunit SRP68 / Signal recognition particle receptor subunit beta / Large ribosomal subunit protein eL14 / Large ribosomal subunit protein eL37
類似検索 - 構成要素
生物種Oryctolagus cuniculus (ウサギ) / Homo sapiens (ヒト)
手法単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.2 Å
データ登録者Jomaa A / Lee JH
資金援助 スイス, 1件
OrganizationGrant number国
Swiss National Science Foundation スイス
引用ジャーナル: Sci Adv / 年: 2021
タイトル: Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.
著者: Jae Ho Lee / Ahmad Jomaa / SangYoon Chung / Yu-Hsien Hwang Fu / Ruilin Qian / Xuemeng Sun / Hao-Hsuan Hsieh / Sowmya Chandrasekar / Xiaotian Bi / Simone Mattei / Daniel Boehringer / Shimon ...著者: Jae Ho Lee / Ahmad Jomaa / SangYoon Chung / Yu-Hsien Hwang Fu / Ruilin Qian / Xuemeng Sun / Hao-Hsuan Hsieh / Sowmya Chandrasekar / Xiaotian Bi / Simone Mattei / Daniel Boehringer / Shimon Weiss / Nenad Ban / Shu-Ou Shan /
要旨: The conserved signal recognition particle (SRP) cotranslationally delivers ~30% of the proteome to the eukaryotic endoplasmic reticulum (ER). The molecular mechanism by which eukaryotic SRP ...The conserved signal recognition particle (SRP) cotranslationally delivers ~30% of the proteome to the eukaryotic endoplasmic reticulum (ER). The molecular mechanism by which eukaryotic SRP transitions from cargo recognition in the cytosol to protein translocation at the ER is not understood. Here, structural, biochemical, and single-molecule studies show that this transition requires multiple sequential conformational rearrangements in the targeting complex initiated by guanosine triphosphatase (GTPase)-driven compaction of the SRP receptor (SR). Disruption of these rearrangements, particularly in mutant SRP54 linked to severe congenital neutropenia, uncouples the SRP/SR GTPase cycle from protein translocation. Structures of targeting intermediates reveal the molecular basis of early SRP-SR recognition and emphasize the role of eukaryote-specific elements in regulating targeting. Our results provide a molecular model for the structural and functional transitions of SRP throughout the targeting cycle and show that these transitions provide important points for biological regulation that can be perturbed in genetic diseases.
履歴
登録2021年2月8日-
ヘッダ(付随情報) 公開2021年6月2日-
マップ公開2021年6月2日-
更新2024年5月1日-
現状2024年5月1日処理サイト: PDBe / 状態: 公開

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構造の表示

ムービー
  • 表面図（断面を密度値に従い着色）
  • 表面レベル: 0.02
  • UCSF Chimeraによる作画
  • ダウンロード
  • 表面図（高さに従い着色）
  • 表面レベル: 0.02
  • UCSF Chimeraによる作画
  • ダウンロード
  • あてはめたモデルとの重ね合わせ
  • 原子モデル: PDB-7nfx
  • 表面レベル: 0.02
  • UCSF Chimeraによる作画
  • ダウンロード
  • 単純化した表面モデル + あてはめた原子モデル
  • 原子モデルPDB-7nfx
  • Jmolによる作画
  • ダウンロード
ムービービューア
構造ビューアEMマップ:
SurfViewMolmilJmol/JSmol
添付画像

emd_12303.png

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マップ

ファイルダウンロード / ファイル: emd_12303.map.gz / 形式: CCP4 / 大きさ: 343 MB / タイプ: IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES)
注釈complex of RNC with SRPG226E and SRP receptor
ボクセルのサイズX=Y=Z: 1.062 Å
密度
表面レベル登録者による: 0.018 / ムービー #1: 0.02
最小 - 最大-0.0595922 - 0.105749294
平均 (標準偏差)0.00037082765 (±0.00575198)
対称性空間群: 1
詳細

EMDB XML:

マップ形状
Axis orderXYZ
Origin000
サイズ448448448
Spacing448448448
セルA=B=C: 475.776 Å
α=β=γ: 90.0 °

CCP4マップ ヘッダ情報:

modeImage stored as Reals
Å/pix. X/Y/Z1.0621.0621.062
M x/y/z448448448
origin x/y/z0.0000.0000.000
length x/y/z475.776475.776475.776
α/β/γ90.00090.00090.000
start NX/NY/NZ7297100
NX/NY/NZ181127145
MAP C/R/S123
start NC/NR/NS000
NC/NR/NS448448448
D min/max/mean-0.0600.1060.000

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添付データ

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試料の構成要素

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全体 : ribosome nascent chain complex with SRP and SRP receptor

全体名称: ribosome nascent chain complex with SRP and SRP receptor
要素
  • 複合体: ribosome nascent chain complex with SRP and SRP receptor
    • 複合体: ribosomal proteins
      • RNA: 28S ribosomal RNA
      • RNA: 5S ribosomal RNA
      • RNA: 5.8S ribosomal RNA
      • タンパク質・ペプチド: uL2
      • タンパク質・ペプチド: uL3
      • タンパク質・ペプチド: 60S ribosomal protein L4
      • タンパク質・ペプチド: 60S ribosomal protein L5
      • タンパク質・ペプチド: 60S ribosomal protein L6
      • タンパク質・ペプチド: uL30
      • タンパク質・ペプチド: 60S ribosomal protein L7a
      • タンパク質・ペプチド: 60S ribosomal protein L9
      • タンパク質・ペプチド: 60S ribosomal protein L10
      • タンパク質・ペプチド: Ribosomal protein L11
      • タンパク質・ペプチド: 60S ribosomal protein L13
      • タンパク質・ペプチド: 60S ribosomal protein L14
      • タンパク質・ペプチド: Ribosomal protein L15
      • タンパク質・ペプチド: uL13
      • タンパク質・ペプチド: uL22
      • タンパク質・ペプチド: eL18
      • タンパク質・ペプチド: 60S RIBOSOMAL PROTEIN EL19
      • タンパク質・ペプチド: eL20
      • タンパク質・ペプチド: eL21
      • タンパク質・ペプチド: Ribosomal protein L22
      • タンパク質・ペプチド: Ribosomal protein L23
      • タンパク質・ペプチド: Ribosomal protein L24
      • タンパク質・ペプチド: uL23
      • タンパク質・ペプチド: Ribosomal protein L26
      • タンパク質・ペプチド: 60S ribosomal protein L27
      • タンパク質・ペプチド: uL15
      • タンパク質・ペプチド: 60S ribosomal protein L29
      • タンパク質・ペプチド: eL30
      • タンパク質・ペプチド: eL31
      • タンパク質・ペプチド: eL32
      • タンパク質・ペプチド: eL33
      • タンパク質・ペプチド: 60S ribosomal protein L34
      • タンパク質・ペプチド: uL29
      • タンパク質・ペプチド: eL36
      • タンパク質・ペプチド: Ribosomal protein L37
      • タンパク質・ペプチド: eL38
      • タンパク質・ペプチド: eL39
      • タンパク質・ペプチド: 60S RIBOSOMAL PROTEIN EL40
      • タンパク質・ペプチド: 60s ribosomal protein l41
      • タンパク質・ペプチド: eL42
      • タンパク質・ペプチド: eL43
      • タンパク質・ペプチド: eL28
    • 複合体: SRP
      • RNA: SRP RNA 7SL
      • タンパク質・ペプチド: Signal recognition particle 19 kDa protein
      • タンパク質・ペプチド: Signal recognition particle 14 kDa protein
      • タンパク質・ペプチド: Signal recognition particle subunit SRP68
      • タンパク質・ペプチド: Signal recognition particle receptor subunit beta
      • タンパク質・ペプチド: Signal recognition particle 9 kDa protein
      • タンパク質・ペプチド: Signal recognition particle 54 kDa protein
      • タンパク質・ペプチド: Signal recognition particle receptor subunit alpha
      • タンパク質・ペプチド: Signal recognition particle subunit SRP72
    • 複合体: Signal Sequence
      • タンパク質・ペプチド: Signal Sequence
  • リガンド: ZINC ION
  • リガンド: MAGNESIUM ION
  • リガンド: GUANOSINE-5'-TRIPHOSPHATE
  • リガンド: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

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超分子 #1: ribosome nascent chain complex with SRP and SRP receptor

超分子名称: ribosome nascent chain complex with SRP and SRP receptor
タイプ: complex / ID: 1 / 親要素: 0 / 含まれる分子: #1-#55
分子量理論値: 3.5 MDa

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超分子 #2: ribosomal proteins

超分子名称: ribosomal proteins / タイプ: complex / ID: 2 / 親要素: 1 / 含まれる分子: #2-#45, #47
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)

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超分子 #3: SRP

超分子名称: SRP / タイプ: complex / ID: 3 / 親要素: 1 / 含まれる分子: #1, #46, #49-#55
由来(天然)生物種: Homo sapiens (ヒト)

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超分子 #4: Signal Sequence

超分子名称: Signal Sequence / タイプ: complex / ID: 4 / 親要素: 1 / 含まれる分子: #48
由来(天然)生物種: Homo sapiens (ヒト)

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分子 #1: SRP RNA 7SL

分子名称: SRP RNA 7SL / タイプ: rna / ID: 1 / コピー数: 1
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 96.828258 KDa
配列文字列: GCCGGGCGCG GUGGCGCGCG CCUGUAGUCC CAGCUACUCG GGAGGCUGAG GCAGGAGGAU CGCUUGAGUC CAGGAGUUCU GGGCUGUAG UGCGCUAUGC CGAUCGGGUG UCCGCACUAA GUUCGGCAUC AAUAUGGUGA CCUCCCGGGA GCGGGGGACC A CCAGGUUG ...文字列:
GCCGGGCGCG GUGGCGCGCG CCUGUAGUCC CAGCUACUCG GGAGGCUGAG GCAGGAGGAU CGCUUGAGUC CAGGAGUUCU GGGCUGUAG UGCGCUAUGC CGAUCGGGUG UCCGCACUAA GUUCGGCAUC AAUAUGGUGA CCUCCCGGGA GCGGGGGACC A CCAGGUUG CCUAAGGAGG GGUGAACCGG CCCAGGUCGG AAACGGAGCA GGUCAAAACU CCCGUGCUGA UCAGUAGUGG GA UCGCGCC UGUGAAUAGC CACUGCACUC CAGCCUGGGC AACAUAGCGA GACCCCGUCU CU

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分子 #2: 28S ribosomal RNA

分子名称: 28S ribosomal RNA / タイプ: rna / ID: 2 / コピー数: 1
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 1.131535875 MDa
配列文字列: CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAG AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGACA UGUGGCGUAC G GAAGACCC ...文字列:
CGCGACCUCA GAUCAGACGU GGCGACCCGC UGAAUUUAAG CAUAUUAGUC AGCGGAGGAG AAGAAACUAA CCAGGAUUCC CUCAGUAAC GGCGAGUGAA CAGGGAAGAG CCCAGCGCCG AAUCCCCGCC CCGCGGCGGG GCGCGGGACA UGUGGCGUAC G GAAGACCC GCUCCCCGGC GCCGCUCGUG GGGGGCCCAA GUCCUUCUGA UCGAGGCCCA GCCCGUGGAC GGUGUGAGGC CG GUAGCGG CCCCCGGCGC GCCGGGCCCG GGUCUUCCCG GAGUCGGGUU GCUUGGGAAU GCAGCCCAAA GCGGGUGGUA AAC UCCAUC UAAGGCUAAA UACCGGCACG AGACCGAUAG UCAACAAGUA CCGUAAGGGA AAGUUGAAAA GAACUUUGAA GAGA GAGUU CAAGAGGGCG UGAAACCGUU AAGAGGUAAA CGGGUGGGGU CCGCGCAGUC CGCCCGGUUC AACCCGGCGG CGGGU CCGG CCGUGUCGGC GGGUCCCCCG ACCGGCGACC GGCCGCCGCC GGGCGCAUUU CCACCGCGGC GGUGCGCCGC GACCGG CUC CGGGACGGCU GGGAAGGCCC GGCGGGGAAG GUGGCUCGGC CGAGUGUUAC AGCCCCCCCG GCAGCAGCAC UCGCCGA AU CCCGGGGCCG AGGGAGCGAG ACCCGUCGCC GCGCUCUCCC CCCUCGGGGG GGCCGGGCCA CCCCUCCCAC GGCGCGAC C GCUCGGGGCG GACUGUCCCC AGUGCGCCCC GGGCGGGUCG CGCCGUCGGG CCCGGGGGAG GGGCCACGCG GCGAGCGCA CGGGGUCGGC GGCGACGUCG GCUACCCACC CGACCCGUCU UGAAACACGG ACCAAGGAGU CUAACACGUG CGCGAGUCGG GGGCUCGCA CGAAAGCCGC CGUGGCGCAA UGAAGGUGAA GGCCGGCGCG CUCGCCGGCC GAGGUGGGAU CCCGAGGCCU C UCCAGUCC GCCGAGGGCG CACCACCGGC CCGUCUCGCC CGCCGCGCCG GGGAGGUGGA GCACGAGCGC ACGUGUUAGG AC CCGAAAG AUGGUGAACU AUGCCUGGGC AGGGCGAAGC CAGAGGAAAC UCUGGUGGAG GUCCGUAGCG GUCCUGACGU GCA AAUCGG UCGUCCGACC UGGGUAUAGG GGCGAAAGAC UAAUCGAACC AUCUAGUAGC UGGUUCCCUC CGAAGUUUCC CUCA GGAUA GCUGGCGCUC UCGCACACGC AGUUUUAUCC GGUAAAGCGA AUGAUUAGAG GUCUUGGGGC CGAAACGAUC UCAAC CUAU UCUCAAACUU UAAAUGGGUA AGAAGCCCGG CUCGCUGGCG UGAGCCGGGC GUGGAAUGGA GUGCCUAGUG GGCCAC UUU UGGUAAGCAG AACUGGCGCU GCGGGAUGAA CCGAACGCCG GGUUAAGGCG CCCGAUGCCG ACGCUCAUCA GACCCCA GA AAAGGUGUUG GUUGAUAUAG AGCCGAAUCA ACUAGCCCUG AAAAUGGAUG GCGCUGGAGC GUCGGGCCCA UACCCGGC C GUCGCCGGCA GUCGAGAGUG GACGGGAGCC CGCCCCCGGA GCCCCGCGGA CGCUACGCCG CGACGAGUAG GAGGGCCGC UGCGGUGAGC CUUGAAGCCU AGGGCGCGGG CCCGGGUGGA GCCGCCGCAG GUGCAGAUCU UGGUGGUAGU AGCAAAUAUU CAAACGAGA ACUUUGAAGG CCGAAGUGGA GAAGGGUUCC AUGUGAACAG CAGUUGAACA UGGGUCAGUC GGUCCUGAGA G AUGGGCGA GCGCCGUUCC GAAGGGACGG GCGAUGGCCU CCGUUGCCCU CGGCCGAUCG AAAGGGAGUC GGGUUCAGAU CC CCGAAUC CGGAGUGGCG GAGAUGGGCG CCGCGAGGCG UCCAGUGCGG UAACGCGACC GAUCCCGGAG AAGCCGGCGG GAG CCCCGG GGAGAGUUCU CUUUUCUUUG UGAAGGGCAG GGCGCCCUGG AAUGGGUUCG CCCCGAGAGA GGGGCCCGUG CCUU GGAAA GCGUCGCGGU UCCGGCGGCG UCCGGUGAGC UCUCGCUGGC CCUUGAAAAU CCGGGGGAGA GGGUGUAAAU CUCGC GCCG GGCCGUACCC AUAUCCGCAG CAGGUCUCCA AGGUGAACAG CCUCUGGCAU GUUGGAACAA UGUAGGUAAG GGAAGU CGG CAAGCCGGAU CCGUAACUUC GGGAUAAGGA UUGGCUCUAA GGGCUGGGUC GGUCGUCGGC CGGCGCCUAG CAGCCGA CU UAGAACUGGU GCGGACCAGG GGAAUCCGAC UGUUUAAUUA AAACAAAGCA UCGCGAAGGC CCGCGGCGGG UGUUGACG C GAUGUGAUUU CUGCCCAGUG CUCUGAAUGU CAAAGUGAAG AAAUUCAAUG AAGCGCGGGU AAACGGCGGG AGUAACUAU GACUCUCUUA AGGUAGCCAA AUGCCUCGUC AUCUAAUUAG UGACGCGCAU GAAUGGAUGA ACGAGAUUCC CACUGUCCCU ACCUACUAU CCAGCGAAAC CACAGCCAAG GGAACGGGCU UGGCGGAAUC AGCGGGGAAA GAAGACCCUG UUGAGCUUGA C UCUAGUCU GGCACGGUGA AGAGACAUGU UUUUUCACUG ACCCGGUGAG GCGGGGGGGC GCUCGCUUCU GGCGCCAAGC GC CCGGCCG CGCGCCGGCC GGGCGCGACC CGCUCCGGGG ACAGUGCCAG GUGGGGAGUU UGACUGGGGC GGUACACCUG UCA AACGGU AACGCAGGUG UCCUAAGGCG AGCUCAGGGA GGACAGAAAC CUCCCGUGGA GCAGAAGGGC AAAAGCUCGC UUGA UCUUG AUUUUCAGUA CGAAUACAGA CCGUGAAAGC GGGGCCUCAC GAUCCUUCUG ACCUUUUGGG UUUUAAGCAG GAGGU GUCA GAAAAGUUAC CACAGGGAUA ACUGGCUUGU GGCGGCCAAG CGUUCAUAGC GACGUCGCUU UUUGAUCCUU CGAUGU CGG CUCUUCCUAU CAUUGUGAAG CAGAAUUCAC CAAGCGUUGG AUUGUUCACC CACUAAUAGG GAACGUGAGC UGGGUUU AG ACCGUCGUGA GACAGGUUAG UUUUACCCUA CUGAUGAUGU GUUGUUGCCA UGGUAAUCCU GCUCAGUACG AGAGGAAC C GCAGGUUCAG ACAUUUGGUG UAUGUGCUUG GCUGAGGAGC CAAUGGGGCG AAGCUACCAU CUGUGGGAUU AUGACUGAA CGCCUCUAAG UCAGAAUCCC GCCCAGGCGG AACGAUACGG CAGCGCCGCG GAGCCUCGGU UGGCCUCGGA UAGCCGGUCC CCCGCGGGG UCCGGUGCGG AGUGCCCUUC GUCCUGGGAA ACGGGGCGCG GCCGGAGAGG CGGCCGCCCC CUCGCCCGUC A CGCACGCC GUUCGUGGGG AACCUGGCGC UAAACCAUUC GUAGACGACC UGCUUCUGGG UCGGGGUUUC GUACGUAGCA GA GCAGCUC CCUCGCUGCG AUCUAUUGAA AGUCAGCCCU CGACACAAGG GUUUGU

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分子 #3: 5S ribosomal RNA

分子名称: 5S ribosomal RNA / タイプ: rna / ID: 3 / コピー数: 1
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 38.691914 KDa
配列文字列:
GUCUACGGCC AUACCACCCU GAACGCGCCC GAUCUCGUCU GAUCUCGGAA GCUAAGCAGG GUCGGGCCUG GUUAGUACUU GGAUGGGAG ACCGCCUGGG AAUACCGGGU GCUGUAGGCU U

GENBANK: GENBANK: 4CXE_4

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分子 #4: 5.8S ribosomal RNA

分子名称: 5.8S ribosomal RNA / タイプ: rna / ID: 4 / コピー数: 1
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 50.143648 KDa
配列文字列:
CGACUCUUAG CGGUGGAUCA CUCGGCUCGU GCGUCGAUGA AGAACGCAGC UAGCUGCGAG AAUUAAUGUG AAUUGCAGGA CACAUUGAU CAUCGACACU UCGAACGCAC UUGCGGCCCC GGGUUCCUCC CGGGGCUACG CCUGUCUGAG CGUCGCU

GENBANK: GENBANK: 4CXE_3

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分子 #5: uL2

分子名称: uL2 / タイプ: protein_or_peptide / ID: 5 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 26.701301 KDa
配列文字列: MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAK VVFRDPYRFK KRTELFIAAE GIHTGQFVY CGKKAQLNIG NVLPVGTMPE GTIVCCLEEK PGDRGKLARA SGNYATVISH NPETKKTRVK LPSGSKKVIS S ANRAVVGV ...文字列:
MGRVIRGQRK GAGSVFRAHV KHRKGAARLR AVDFAERHGY IKGIVKDIIH DPGRGAPLAK VVFRDPYRFK KRTELFIAAE GIHTGQFVY CGKKAQLNIG NVLPVGTMPE GTIVCCLEEK PGDRGKLARA SGNYATVISH NPETKKTRVK LPSGSKKVIS S ANRAVVGV VAGGGRIDKP ILKAGRAYHK YKAKRNCWPR VRGVAMNPVE HPFGGGNHQH IGKPSTIRRD APAGRKVGLI AA RRTGR

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分子 #6: uL3

分子名称: uL3 / タイプ: protein_or_peptide / ID: 6 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 46.107977 KDa
配列文字列: MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM ...文字列:
MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGI VGYVETPRGL RTFKTVFAEH ISDECKRRFY KNWHKSKKKA FTKYCKKWQD DAGKRQLDKD FSSMKKYCQV I RVLAHTQM RLLPLRQKKA HLMEIQVNGG TVAEKLDWAR ERLEQQVPVS QVFGQDEMID VIGVTKGKGY KGVTSRWHTK KL PRKTHRG LRKVACIGAW HPARVAFSVA RAGQKGYHHR TEINKKIYKI GQGYLIKDGK LIKNNASTDY DLSDKSINPL GGF VHYGEV TNDFVMLKGC VVGTKKRVLT LRKSLLVQTK RRALEKIDLK FIDTTSKFGH GRFQTVEEKK AFMGPLKKDR IAKE EGA

UniProtKB: Large ribosomal subunit protein uL3

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分子 #7: 60S ribosomal protein L4

分子名称: 60S ribosomal protein L4 / タイプ: protein_or_peptide / ID: 7 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 46.388855 KDa
配列文字列: MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV ...文字列:
MACARPLISV YSEKGESSGK NVTLPAVFKA PIRPDIVNFV HTNLRKNNRQ PYAVSELAGH QTSAESWGTG RAVARIPRVR GGGTHRSGQ GAFGNMCRGG RMFAPTKTWR RWHRRVNTTQ KRYAICSALA ASALPALVMS KGHRIEEVPE LPLVVEDKVE G YKKTKEAV LLLKKLKAWN DIKKVYASQR MRAGKGKMRN RRRIQRRGPC VIYNEDNGIV KAFRNIPGIT LLNVTKLNIL KL APGGHVG RFCIWTESAF RKLDDLYGTW RKAASLKSNY NLPMHKMLNT DLSRILKSPE IQRALRAPRK KIHRRVLKKN PLK NLRIML KLNPYAKTMR RNTILRQARN HKLRVERAAA ALAAKSDPKE APAKKKPVVG KKKKPVVGRK AAAAKKPAAD KKAA DKRAG PEDKKPAA

UniProtKB: Large ribosomal subunit protein uL4

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分子 #8: 60S ribosomal protein L5

分子名称: 60S ribosomal protein L5 / タイプ: protein_or_peptide / ID: 8 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 34.481828 KDa
配列文字列: MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD ...文字列:
MGFVKVVKNK AYFKRYQVKF RRRREGKTDY YARKRLVIQD KNKYNTPKYR MIVRVTNRDI ICQIAYARIE GDMIVCAAYA HELPKYGVK VGLTNYAAAY CTGLLLARRL LNRFGMDKIY EGQVEVTGDE YNVESIDGQP GAFTCYLDAG LARTTTGNKV F GALKGAVD GGLSIPHSTK RFPGYDSESK EFNAEVHRKH IMGQNVADYM RYLMEEDEDA YKKQFSQYIK NNVTPDMMEE MY KKAHAAI RENPVYEKKP KREVKKKRWN RPKMSLAQKK DRVAQKKASF LRAQERAAES

UniProtKB: Large ribosomal subunit protein uL18

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分子 #9: 60S ribosomal protein L6

分子名称: 60S ribosomal protein L6 / タイプ: protein_or_peptide / ID: 9 / 詳細: Based on sequence from 3JAG / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 33.055297 KDa
配列文字列: MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGRKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL ...文字列:
MAGEKAPAAK PDATKKSPAK KADHARGKAK KKTLAEKKPK KGKPHCSRNP VLVRGIGRYS RSAMYSRKAL YKRKYAAPKS RIERKKKRE KVLATVTKPV GGDKNGGTRV VKLRKMPRYY PTEDVPRKLL SHGRKPFSQH VRKLRASITP GTILIILTGR H RGKRVVFL KQLSSGLLLV TGPLSLNRVP LRRTHQKFVI ATSTKIDISG VKIPKHLTDA YFKKKQLRKP RHQEGEIFDT EK EKYEITE QRKVDQKAVD SQILPKIKAV PQLQGYLRSV FALTNGVYPH KLVF

UniProtKB: Large ribosomal subunit protein eL6

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分子 #10: uL30

分子名称: uL30 / タイプ: protein_or_peptide / ID: 10 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 26.662787 KDa
配列文字列: NFAELKIKRL RKKFAQKMLR KARRKLIYEK AKHYHKEYRQ MYRTEIRMAR MARKAGNFYV PAEPKLAFVI RIRGINGVSP KVRKVLQLL RLRQIFNGTF VKLNKASINM LRIVEPYIAW GYPNLKSVNE LIYKRGYGKI NKKRIALTDN ALIARSLGKY G IICMEDLI ...文字列:
NFAELKIKRL RKKFAQKMLR KARRKLIYEK AKHYHKEYRQ MYRTEIRMAR MARKAGNFYV PAEPKLAFVI RIRGINGVSP KVRKVLQLL RLRQIFNGTF VKLNKASINM LRIVEPYIAW GYPNLKSVNE LIYKRGYGKI NKKRIALTDN ALIARSLGKY G IICMEDLI HEIYTVGKRF KEANNFLWPF KLSSPRGGMK KKTTHFVEGE DAGNREDQIN RLIRRMN

UniProtKB: Large ribosomal subunit protein uL30

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分子 #11: 60S ribosomal protein L7a

分子名称: 60S ribosomal protein L7a / タイプ: protein_or_peptide / ID: 11 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 36.267605 KDa
配列文字列: MSSYRLGYCM KEERHNLVLC LWSQSPGILN SKCLWPFTNI HLLVGALPRE GAGGAWGGGR SEQLPTCSTT HHDFTWDKKV VNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQV LDRQTATQLL KLAHKYRPET K QEKKQRLL ...文字列:
MSSYRLGYCM KEERHNLVLC LWSQSPGILN SKCLWPFTNI HLLVGALPRE GAGGAWGGGR SEQLPTCSTT HHDFTWDKKV VNPLFEKRP KNFGIGQDIQ PKRDLTRFVK WPRYIRLQRQ RAILYKRLKV PPAINQFTQV LDRQTATQLL KLAHKYRPET K QEKKQRLL ARAEKKAAGK GDVPTKRPPV LRAGVNTVTT LVENKKAQLV VIAHDVDPIE LVVFLPALCR KMGVPYCILK GK ARLCRLV HRKTCTTVAF TQVNSEDKGA LAKLVEAIRT NYNDRYDEIR RHWGGNVLGP KSVARIAKLE KAKAKELATK LG

UniProtKB: Large ribosomal subunit protein eL8

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分子 #12: 60S ribosomal protein L9

分子名称: 60S ribosomal protein L9 / タイプ: protein_or_peptide / ID: 12 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 21.871418 KDa
配列文字列: MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK ...文字列:
MKTILSNQTV DIPENVDISL KGRTVIVKGP RGTLRRDFNH INVELSLLGK KKKRLRVDKW WGNRKELATV RTICSHVQNM IKGVTLGFR YKMRSVYAHF PINVVIQENG SLVEIRNFLG EKYIRRVRMR PGVACSVSQA QKDELVLEGN DIELVSNSAA L IQQATTVK NKDIRKFLDG IYVSEKGTVQ QADE

UniProtKB: Large ribosomal subunit protein uL6

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分子 #13: 60S ribosomal protein L10

分子名称: 60S ribosomal protein L10 / タイプ: protein_or_peptide / ID: 13 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 24.643057 KDa
配列文字列: MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS ...文字列:
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRV RLHPFHVIRI NKMLSCAGAD RLQTGMRGAF GKPQGTVARV HIGQVIMSIR TKLQNKEHVV EALRRAKFKF P GRQKIHIS KKWGFTKFNA DEFEDMVAEK RLIPDGCGVK YIPNRGPLDK WRALHS

UniProtKB: Large ribosomal subunit protein uL16

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分子 #14: Ribosomal protein L11

分子名称: Ribosomal protein L11 / タイプ: protein_or_peptide / ID: 14 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 20.288465 KDa
配列文字列:
MAQDQGEKEN PMRELRIRKL CLNICVGESG DRLTRAAKVL EQLTGQTPVF SKARYTVRSF GIRRNEKIAV HCTVRGAKAE EILEKGLKV REYELRKNNF SDTGNFGFGI QEHIDLGIKY DPSIGIYGLD FYVVLGRPGF SIADKKRRTG CIGAKHRISK E EAMRWFQQ KYDGIILPGK

UniProtKB: Large ribosomal subunit protein uL5

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分子 #15: 60S ribosomal protein L13

分子名称: 60S ribosomal protein L13 / タイプ: protein_or_peptide / ID: 15 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 24.216525 KDa
配列文字列: APSRNGMILK PHFHKDWQRR VATWFNQPAR KIRRRKARQA RARRIAPRPA SGPLRPIVRC PTVRYHTKVR AGRGFSLEEL RVAGIHKKV ARTIGISVDP RRRNKSTESL QANVQRLKEY RSKLVLFPRK PSAPKKGDSS AEELKLATQL TGPVMPIRNV F KKEKARVI ...文字列:
APSRNGMILK PHFHKDWQRR VATWFNQPAR KIRRRKARQA RARRIAPRPA SGPLRPIVRC PTVRYHTKVR AGRGFSLEEL RVAGIHKKV ARTIGISVDP RRRNKSTESL QANVQRLKEY RSKLVLFPRK PSAPKKGDSS AEELKLATQL TGPVMPIRNV F KKEKARVI TEEEKNFKAF ASLRMARANA RLFGIRAKRA KEAAEQDVEK KK

UniProtKB: Uncharacterized protein

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分子 #16: 60S ribosomal protein L14

分子名称: 60S ribosomal protein L14 / タイプ: protein_or_peptide / ID: 16 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 23.810432 KDa
配列文字列: AVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG ...文字列:
AVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF ILKFPHSARQ KYVRKAWEKA DINTKWAAT RWAKKIEARE RKAKMTDFDR YKVMKAKKMR NRIIKNEVKK LQRAALLKAS PKKAPVAKGA VAAAAAAAKV P AKKATAAG KKAAAQKAPA QKAPAQKAAG QKAAQPPKAQ KGQKPPAQKA PAPKASGKKA

UniProtKB: Large ribosomal subunit protein eL14

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分子 #17: Ribosomal protein L15

分子名称: Ribosomal protein L15 / タイプ: protein_or_peptide / ID: 17 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 24.207285 KDa
配列文字列: MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG ...文字列:
MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGV NQLKFARSLQ SVAEERAGRH CGALRVLNSY WVGEDSTYKF FEVILIDPFH KAIRRNPDTQ WITKPVHKHR E MRGLTSAG RKSRGLGKGH KFHHTIGGSR RAAWRRRNTL QLHRYR

UniProtKB: Large ribosomal subunit protein eL15

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分子 #18: uL13

分子名称: uL13 / タイプ: protein_or_peptide / ID: 18 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 23.248924 KDa
配列文字列: QVLVLDGRGH LLGRLAAIVA KQVLLGRKVV VVRCEGINIS GNFYRNKLKY LAFLRKRMNT NPSRGPYHFR APSRIFWRTV RGMLPHKTK RGQAALDRLK VFDGIPPPYD KKKRMVVPAA LKVVRLKPTR KFAYLGRLAH EVGWKYQAVT ATLEEKRKEK A KIHYRKKK ...文字列:
QVLVLDGRGH LLGRLAAIVA KQVLLGRKVV VVRCEGINIS GNFYRNKLKY LAFLRKRMNT NPSRGPYHFR APSRIFWRTV RGMLPHKTK RGQAALDRLK VFDGIPPPYD KKKRMVVPAA LKVVRLKPTR KFAYLGRLAH EVGWKYQAVT ATLEEKRKEK A KIHYRKKK QLMRLRKQAE KNVEKKIDRF TEVLKTHGFL V

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分子 #19: uL22

分子名称: uL22 / タイプ: protein_or_peptide / ID: 19 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 17.758678 KDa
配列文字列:
VRYSLDPENP TKSCKSRGSN LRVHFKNTRE TAQAIKGMHI RKATKYLKDV TLKKQCVPFR RYNGGVGRCA QAKQWGWTQG RWPKKSAEF LLHMLKNAES NAELKGLDVD SLVIEHIQVN KAPKMRRRTY RAHGRINPYM SSPCHIEMIL TEKE

UniProtKB: Large ribosomal subunit protein uL22

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分子 #20: eL18

分子名称: eL18 / タイプ: protein_or_peptide / ID: 20 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 21.457391 KDa
配列文字列:
GVDIRHNKDR KVRRKEPKSQ DIYLRLLVKL YRFLARRTNS TFNQVVLKRL FMSRTNRPPL SLSRMIRKMK LPGREGKTAV VVGTITDDV RVQEVPKLKV CALRVSSRAR SRILKAGGKI LTFDQLALDS PKGCGTVLLS GPRKGREVYR HFGKAPGTPH S HTKPYVRS KGRKFERARG RRASRGYKN

UniProtKB: Large ribosomal subunit protein uL15/eL18 domain-containing protein

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分子 #21: 60S RIBOSOMAL PROTEIN EL19

分子名称: 60S RIBOSOMAL PROTEIN EL19 / タイプ: protein_or_peptide / ID: 21 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 21.613033 KDa
配列文字列:
SMLRLQKRLA SSVLRCGKKK VWLDPNETNE IANANSRQQI RKLIKDGLII RKPVTVHSRA RCRKNTLARR KGRHMGIGKR KGTANARMP EKVTWMRRMR ILRRLLRRYR ESKKIDRHMY HSLYLKVKGN VFKNKRILME HIHKLKADKA RKKLLADQAE A RRSKTKEA RKRREERLQA KK

UniProtKB: Large ribosomal subunit protein eL19

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分子 #22: eL20

分子名称: eL20 / タイプ: protein_or_peptide / ID: 22 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 20.696363 KDa
配列文字列:
KASGTLREYK VVGRCLPTPK CRTPPLYRMR IFAPNHVVAK SRFWYFVSQL KKMKKSSGEI VYCGQVFEKS PLRVKNFGIW LRYDSRSGT HNMYREYRDL TTAGAVTQCY RDMGARHRAR AHSIQIMKVE EIAASKCRRP AVKQFHDSKI KFPLPHRVLR R QHKPRFTT KRPNTFF

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分子 #23: eL21

分子名称: eL21 / タイプ: protein_or_peptide / ID: 23 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 18.609988 KDa
配列文字列:
MTNTKGKRRG TRYMFSRPFR KHGVVPLATY MRIYKKGDIV DIKGMGTVQK GMPHKCYHGK TGRVYNVTQH AVGIVVNKQV KGKILAKRI NVRIEHIKHS KSRDSFLKRV KENDQKKKEA KEKGTWVQLK RQPAPPREAH FVRTNGKEPE LLEPIPYEFM A

UniProtKB: Large ribosomal subunit protein eL21

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分子 #24: Ribosomal protein L22

分子名称: Ribosomal protein L22 / タイプ: protein_or_peptide / ID: 24 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 11.481249 KDa
配列文字列:
QVLKFTLDCT HPVEDGIMDA ANFEQFLQER IKVNGKAGNL GGGVVTIERS KSKITVTSEV PFSKRYLKYL TKKYLKKNNL RDWLRVVAN SKESYELRYF

UniProtKB: Large ribosomal subunit protein eL22

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分子 #25: Ribosomal protein L23

分子名称: Ribosomal protein L23 / タイプ: protein_or_peptide / ID: 25 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.892505 KDa
配列文字列:
MSKRGRGGSS GAKFRISLGL PVGAVINCAD NTGAKNLYII SVKGIKGRLN RLPAAGVGDM VMATVKKGKP ELRKKVHPAV VIRQRKSYR RKDGVFLYFE DNAGVIVNNK GEMKGSAITG PVAKECADLW PRIASNAGSI A

UniProtKB: Large ribosomal subunit protein uL14

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分子 #26: Ribosomal protein L24

分子名称: Ribosomal protein L24 / タイプ: protein_or_peptide / ID: 26 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 7.512774 KDa
配列文字列:
MKVELCSFSG YKIYPGHGRR YARTDGKVFQ FLNAKCESAF LSKRNPRQIN WTVLYRRKHK KGQ

UniProtKB: Large ribosomal subunit protein eL24

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分子 #27: uL23

分子名称: uL23 / タイプ: protein_or_peptide / ID: 27 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 17.768246 KDa
配列文字列:
MAPKAKKEAP APPKVEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY PRKSAPRRNK LDHYAIIKFP LTTESAMKK IEDNNTLVFI VDVKANKHQI KQAVKKLYDI DVAKVNTLIR PDGEKKAYVR LAPDYDALDV ANKIGII

UniProtKB: Large ribosomal subunit protein uL23

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分子 #28: Ribosomal protein L26

分子名称: Ribosomal protein L26 / タイプ: protein_or_peptide / ID: 28 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 17.303363 KDa
配列文字列:
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG HYKGQQIGKV VQVYRKKYVI YIERVQREK ANGTTVHVGI HPSKVVITRL KLDKDRKKIL ERKAKSRQVG KEKGKYKEET IEKMQE

UniProtKB: Large ribosomal subunit protein uL24

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分子 #29: 60S ribosomal protein L27

分子名称: 60S ribosomal protein L27 / タイプ: protein_or_peptide / ID: 29 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 15.835831 KDa
配列文字列:
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDI PLDKTVVNKD VFRDPALKRK ARREAKVKFE ERYKTGKNKW FFQKLRF

UniProtKB: Large ribosomal subunit protein eL27

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分子 #30: uL15

分子名称: uL15 / タイプ: protein_or_peptide / ID: 30 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 16.620561 KDa
配列文字列:
MPSRLRKTRK LRGHVSHGHG RIGKHRKHPG GRGNAGGMHH HRINFDKYHP GYFGKVGMRH YHLKRNQSFC PTVNLDKLWT LVSEQTRVN AAKNKTGAAP IIDVVRSGYY KVLGKGKLPK QPVIVKAKFF SRRAEEKIKG VGGACVLVA

UniProtKB: Large ribosomal subunit protein uL15

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分子 #31: 60S ribosomal protein L29

分子名称: 60S ribosomal protein L29 / タイプ: protein_or_peptide / ID: 31 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 24.608236 KDa
配列文字列: MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALVKPKE VKPTIPKGV SRKLDRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGKAQA E TKPKAQAQ ...文字列:
MAKSKNHTTH NQSRKWHRNG IKKPRSQRYE SLKGVDPKFL RNMRFAKKHN KKGLKKMQAN NAKAMAARAE AIKALVKPKE VKPTIPKGV SRKLDRLAYI AHPKLGRRAR ARIARGLRLS RPQTKAKAKT EPQIKGKVKA QIKAQAQAQI KSKGKGKAQA E TKPKAQAQ AKPKAQAQGK PKAQAQAKPK AHAQAKPKAQ AQAKPKAQAQ TKRTGVTPGL LSAWG

UniProtKB: Large ribosomal subunit protein eL29

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分子 #32: eL30

分子名称: eL30 / タイプ: protein_or_peptide / ID: 32 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 10.496355 KDa
配列文字列:
SINSRLQLVM KSGKYVLGYK QTLKMIRQGK AKLVILANNC PALRKSEIEY YAMLAKTGVH HYSGNNIELG TACGKYYRVC TLAIIDPGD SDIIR

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分子 #33: eL31

分子名称: eL31 / タイプ: protein_or_peptide / ID: 33 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.494938 KDa
配列文字列:
MAPAKKGGEK KKGRSAINEV VTREYTINIH KRIHGVGFKK RAPRALKEIR KFAMKEMGTP DVRIDTRLNK AVWAKGIRNV PYRIRVRLS RKRNEDEDSP NKLYTLVTYV PVTTFKNLQT VNVDEN

UniProtKB: Large ribosomal subunit protein eL31

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分子 #34: eL32

分子名称: eL32 / タイプ: protein_or_peptide / ID: 34 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 15.022021 KDa
配列文字列:
AALRPLVKPK IVKKRTKKFI RHQSDRYVKI KRNWRKPRGI DNRVRRRFKG QILMPNIGYG SNKKTKHMLP SGFRKFLVHN VKELEVLLM CNKSYCAEIA HNVSSKNRKA IVERAAQLAI RVTNPNARL

UniProtKB: Large ribosomal subunit protein eL32

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分子 #35: eL33

分子名称: eL33 / タイプ: protein_or_peptide / ID: 35 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 12.580809 KDa
配列文字列:
MSGRLWCKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFR SNLPAKAIGH RIRVMLYPSR I

UniProtKB: Large ribosomal subunit protein eL33

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分子 #36: 60S ribosomal protein L34

分子名称: 60S ribosomal protein L34 / タイプ: protein_or_peptide / ID: 36 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.557543 KDa
配列文字列:
MSLPGRCLEA ATMVQRLTYR RRLSYNTASN KTRLSRTPGN RIVYLYTKKV GKAPKSACGV CPGRLRGVRA VRPKVLMRLS KTKKHVSRA YGGSMCAKCV RDRIKRAFLI EEQKIVVKVL KAQAQSQKAK

UniProtKB: Large ribosomal subunit protein eL34

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分子 #37: uL29

分子名称: uL29 / タイプ: protein_or_peptide / ID: 37 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 14.566599 KDa
配列文字列:
MAKIKARDLR GKKKEELLKQ LDDLKVELSQ LRVAKVTGGA ASKLSKIRVV RKSIARVLTV INQTQKENLR KFYKGKKYKP LDLRPKKTR AMRRRLNKHE ESLKTKKQQR KERLYPLRKY AVKA

UniProtKB: Large ribosomal subunit protein uL29

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分子 #38: eL36

分子名称: eL36 / タイプ: protein_or_peptide / ID: 38 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 12.132639 KDa
配列文字列:
ALRYPMAVGL NKGHKVTKNV SKPRHSRRRG RLTKHTKFVR DMIREVCGFA PYERRAMELL KVSKDKRALK FIKKRVGTHI RAKRKREEL SSVLAAMRKA AAKKD

+
分子 #39: Ribosomal protein L37

分子名称: Ribosomal protein L37 / タイプ: protein_or_peptide / ID: 39 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 11.111032 KDa
配列文字列:
MTKGTSSFGK RRNKTHTLCR RCGSKAYHLQ KSTCGKCGYP AKRKRKYNWS AKAKRRNTTG TGRMRHLKIV YRRFRHGFRE GTTPKPKRA AVAASSSS

UniProtKB: Large ribosomal subunit protein eL37

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分子 #40: eL38

分子名称: eL38 / タイプ: protein_or_peptide / ID: 40 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 8.107752 KDa
配列文字列:
PRKIEEIKDF LLTARRKDAK SVKIKKNKDN VKFKVRCSRY LYTLVITDKE KAEKLKQSLP PGLAVKELK

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分子 #41: eL39

分子名称: eL39 / タイプ: protein_or_peptide / ID: 41 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 6.426759 KDa
配列文字列:
MSSHKTFRIK RFLAKKQKQN RPIPQWIRMK TGNKIRYNSK RRHWRRTKLG L

UniProtKB: Large ribosomal subunit protein eL39

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分子 #42: 60S RIBOSOMAL PROTEIN EL40

分子名称: 60S RIBOSOMAL PROTEIN EL40 / タイプ: protein_or_peptide / ID: 42 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 6.199574 KDa
配列文字列:
IIEPSLRQLA QKYNCDKMIC RKCYARLHPR AVNCRKKKCG HTNNLRPKKK VK

UniProtKB: Ubiquitin-ribosomal protein eL40 fusion protein

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分子 #43: 60s ribosomal protein l41

分子名称: 60s ribosomal protein l41 / タイプ: protein_or_peptide / ID: 43 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 3.473451 KDa
配列文字列:
MRAKWRKKRM RRLKRKRRKM RQRSK

UniProtKB: Small ribosomal subunit protein eS32

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分子 #44: eL42

分子名称: eL42 / タイプ: protein_or_peptide / ID: 44 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 12.329798 KDa
配列文字列:
MVNVPKTRRT FCKKCGKHQP HKVTQYKKGK DSLYAQGKRR YDRKQSGYGG QTKPIFRKKA KTTKKIVLRL ECVEPNCRSK RMLAIKRCK HFELGGDKKR KGQVIQ

UniProtKB: Large ribosomal subunit protein eL42

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分子 #45: eL43

分子名称: eL43 / タイプ: protein_or_peptide / ID: 45 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 10.29935 KDa
配列文字列:
MAKRTKKVGI VGKYGTRYGA SLRKMVKKIE ISQHAKYTCS FCGKTKMKRR AVGIWHCGSC MKTVAGGAWT YNTTSAVTVK SAIRRLKEL KDQ

UniProtKB: Large ribosomal subunit protein eL43

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分子 #46: Signal recognition particle 19 kDa protein

分子名称: Signal recognition particle 19 kDa protein / タイプ: protein_or_peptide / ID: 46 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 16.183746 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列:
MACAAARSPA DQDRFICIYP AYLNNKKTIA EGRRIPISKA VENPTATEIQ DVCSAVGLNV FLEKNKMYSR EWNRDVQYRG RVRVQLKQE DGSLCLVQFP SRKSVMLYAA EMIPKLKTRT QKTGGADQSL QQGEGSKKGK GKKKK

UniProtKB: Signal recognition particle 19 kDa protein

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分子 #47: eL28

分子名称: eL28 / タイプ: protein_or_peptide / ID: 47 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Oryctolagus cuniculus (ウサギ)
分子量理論値: 15.783614 KDa
配列文字列:
MSAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG VEPAADGKGV VVVMKRRSGQ RKPATSYVRT TINKNARAT LSSIRHMIRK NKYHPDLRMA AIRRASAILR SQKPVMVKRK RTRPTKSS

UniProtKB: Large ribosomal subunit protein eL28

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分子 #48: Signal Sequence

分子名称: Signal Sequence / タイプ: protein_or_peptide / ID: 48
詳細: this entry was modeled as a poly-alanine protein chain
コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 1.805216 KDa
組換発現生物種: Oryctolagus cuniculus (ウサギ)
配列文字列:
(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK)(UNK)(UNK)(UNK) (UNK)(UNK)(UNK) (UNK)(UNK)

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分子 #49: Signal recognition particle 14 kDa protein

分子名称: Signal recognition particle 14 kDa protein / タイプ: protein_or_peptide / ID: 49 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 14.59597 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列:
MVLLESEQFL TELTRLFQKC RTSGSVYITL KKYDGRTKPI PKKGTVEGFE PADNKCLLRA TDGKKKISTV VSSKEVNKFQ MAYSNLLRA NMDGLKKRDK KNKTKKTKAA AAAAAAAPAA AATAPTTAAT TAATAAQ

UniProtKB: Signal recognition particle 14 kDa protein

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分子 #50: Signal recognition particle subunit SRP68

分子名称: Signal recognition particle subunit SRP68 / タイプ: protein_or_peptide / ID: 50 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 70.831578 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MAAEKQVPGG GGGGGSGGGG GSGGGGSGGG RGAGGEENKE NERPSAGSKA NKEFGDSLSL EILQIIKESQ QQHGLRHGDF QRYRGYCSR RQRRLRKTLN FKMGNRHKFT GKKVTEELLT DNRYLLLVLM DAERAWSYAM QLKQEANTEP RKRFHLLSRL R KAVKHAEE ...文字列:
MAAEKQVPGG GGGGGSGGGG GSGGGGSGGG RGAGGEENKE NERPSAGSKA NKEFGDSLSL EILQIIKESQ QQHGLRHGDF QRYRGYCSR RQRRLRKTLN FKMGNRHKFT GKKVTEELLT DNRYLLLVLM DAERAWSYAM QLKQEANTEP RKRFHLLSRL R KAVKHAEE LERLCESNRV DAKTKLEAQA YTAYLSGMLR FEHQEWKAAI EAFNKCKTIY EKLASAFTEE QAVLYNQRVE EI SPNIRYC AYNIGDQSAI NELMQMRLRS GGTEGLLAEK LEALITQTRA KQAATMSEVE WRGRTVPVKI DKVRIFLLGL ADN EAAIVQ AESEETKERL FESMLSECRD AIQVVREELK PDQKQRDYIL EGEPGKVSNL QYLHSYLTYI KLSTAIKRNE NMAK GLQRA LLQQQPEDDS KRSPRPQDLI RLYDIILQNL VELLQLPGLE EDKAFQKEIG LKTLVFKAYR CFFIAQSYVL VKKWS EALV LYDRVLKYAN EVNSDAGAFK NSLKDLPDVQ ELITQVRSEK CSLQAAAILD ANDAHQTETS SSQVKDNKPL VERFET FCL DPSLVTKQAN LVHFPPGFQP IPCKPLFFDL ALNHVAFPPL EDKLEQKTKS GLTGYIKGIF GFRS

UniProtKB: Signal recognition particle subunit SRP68

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分子 #51: Signal recognition particle receptor subunit beta

分子名称: Signal recognition particle receptor subunit beta / タイプ: protein_or_peptide / ID: 51 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 29.737201 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MASADSRRVA DGGGAGGTFQ PYLDTLRQEL QQTDPTLLSV VVAVLAVLLT LVFWKLIRSR RSSQRAVLLV GLCDSGKTLL FVRLLTGLY RDTQTSITDS CAVYRVNNNR GNSLTLIDLP GHESLRLQFL ERFKSSARAI VFVVDSAAFQ REVKDVAEFL Y QVLIDSMG ...文字列:
MASADSRRVA DGGGAGGTFQ PYLDTLRQEL QQTDPTLLSV VVAVLAVLLT LVFWKLIRSR RSSQRAVLLV GLCDSGKTLL FVRLLTGLY RDTQTSITDS CAVYRVNNNR GNSLTLIDLP GHESLRLQFL ERFKSSARAI VFVVDSAAFQ REVKDVAEFL Y QVLIDSMG LKNTPSFLIA CNKQDIAMAK SAKLIQQQLE KELNTLRVTR SAAPSTLDSS STAPAQLGKK GKEFEFSQLP LK VEFLECS AKGGRGDVGS ADIQDLEKWL AKIA

UniProtKB: Signal recognition particle receptor subunit beta

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分子 #52: Signal recognition particle 9 kDa protein

分子名称: Signal recognition particle 9 kDa protein / タイプ: protein_or_peptide / ID: 52 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 10.127763 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列:
MPQYQTWEEF SRAAEKLYLA DPMKARVVLK YRHSDGNLCV KVTDDLVCLV YKTDQAQDVK KIEKFHSQLM RLMVAKEARN VTMETE

UniProtKB: Signal recognition particle 9 kDa protein

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分子 #53: Signal recognition particle 54 kDa protein

分子名称: Signal recognition particle 54 kDa protein / タイプ: protein_or_peptide / ID: 53 / 詳細: this protein has mutation at position G226E / コピー数: 1 / 光学異性体: LEVO
EC番号: 加水分解酵素; 酸無水物に作用; GTPに作用・細胞または細胞小器官の運動に関与
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 55.847734 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MVLADLGRKI TSALRSLSNA TIINEEVLNA MLKEVCTALL EADVNIKLVK QLRENVKSAI DLEEMASGLN KRKMIQHAVF KELVKLVDP GVKAWTPTKG KQNVIMFVGL QGSGKTTTCS KLAYYYQRKG WKTCLICADT FRAGAFDQLK QNATKARIPF Y GSYTEMDP ...文字列:
MVLADLGRKI TSALRSLSNA TIINEEVLNA MLKEVCTALL EADVNIKLVK QLRENVKSAI DLEEMASGLN KRKMIQHAVF KELVKLVDP GVKAWTPTKG KQNVIMFVGL QGSGKTTTCS KLAYYYQRKG WKTCLICADT FRAGAFDQLK QNATKARIPF Y GSYTEMDP VIIASEGVEK FKNENFEIII VDTSGRHKQE DSLFEEMLQV ANAIQPDNIV YVMDASIEQA CEAQAKAFKD KV DVASVIV TKLDGHAKGG GALSAVAATK SPIIFIGTGE HIDDFEPFKT QPFISKLLGM GDIEGLIDKV NELKLDDNEA LIE KLKHGQ FTLRDMYEQF QNIMKMGPFS QILGMIPGFG TDFMSKGNEQ ESMARLKKLM TIMDSMNDQE LDSTDGAKVF SKQP GRIQR VARGSGVSTR DVQELLTQYT KFAQMVKKMG GIKGLFKGGD MSKNVSQSQM AKLNQQMAKM MDPRVLHHMG GMAGL QSMM RQFQQGAAGN MKGMMGFNNM

UniProtKB: Signal recognition particle subunit SRP54

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分子 #54: Signal recognition particle receptor subunit alpha

分子名称: Signal recognition particle receptor subunit alpha / タイプ: protein_or_peptide / ID: 54
詳細: a linker in the protein was modeled as poly-alanine chain
コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 69.908109 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MLDFFTIFSK GGLVLWCFQG VSDSCTGPVN ALIRSVLLQE RGGNNSFTHE ALTLKYKLDN QFELVFVVGF QKILTLTYVD KLIDDVHRL FRDKYRTEIQ QQSALSLLNG TFDFQNDFLR LLREAEESSK IRAPTTMKKF EDSEKAKKPV RSMIETRGEK P KEKAKNSK ...文字列:
MLDFFTIFSK GGLVLWCFQG VSDSCTGPVN ALIRSVLLQE RGGNNSFTHE ALTLKYKLDN QFELVFVVGF QKILTLTYVD KLIDDVHRL FRDKYRTEIQ QQSALSLLNG TFDFQNDFLR LLREAEESSK IRAPTTMKKF EDSEKAKKPV RSMIETRGEK P KEKAKNSK KKGAKKEGSD GPLATSKPVP AEKSGLPVGP ENGVELSKEE LIRRKREEFI QKHGRGMEKS NKSTKSDAPK EK GKKAPRV WELGGCANKE VLDYSTPTTN GTPEAALSED INLIRGTGSG GQLQDLDCSS SDDEGAAQNS TKPSATKGTL GGM FGMLKG LVGSKSLSRE DMESVLDKMR DHLIAKNVAA DIAVQLCESV ANKLEGKVMG TFSTVTSTVK QALQESLVQI LQPQ RRVDM LRDIMDAQRR QRPYVVTFCG VNGVGKSTNL AKISFWLLEN GFSVLIAACD TFRAGAVEQL RTHTRRLSAL HPPEK HGGR TMVQLFEKGY GKDAAGIAME AIAFARNQGF DVVLVDTAGR MQDNAPLMTA LAKLITVNTP DLVLFVGEAL VGNEAV DQL VKFNRALADH SMAQTPRLID GIVLTKFDTI DDKVGAAISM TYITSKPIVF VGTGQTYCDL RSLNAKAVVA ALMKA

UniProtKB: Signal recognition particle receptor subunit alpha

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分子 #55: Signal recognition particle subunit SRP72

分子名称: Signal recognition particle subunit SRP72 / タイプ: protein_or_peptide / ID: 55 / コピー数: 1 / 光学異性体: LEVO
由来(天然)生物種: Homo sapiens (ヒト)
分子量理論値: 74.720273 KDa
組換発現生物種: Escherichia coli (大腸菌)
配列文字列: MASGGSGGVS VPALWSEVNR YGQNGDFTRA LKTVNKILQI NKDDVTALHC KVVCLIQNGS FKEALNVINT HTKVLANNSL SFEKAYCEY RLNRIENALK TIESANQQTD KLKELYGQVL YRLERYDECL AVYRDLVRNS QDDYDEERKT NLSAVVAAQS N WEKVVPEN ...文字列:
MASGGSGGVS VPALWSEVNR YGQNGDFTRA LKTVNKILQI NKDDVTALHC KVVCLIQNGS FKEALNVINT HTKVLANNSL SFEKAYCEY RLNRIENALK TIESANQQTD KLKELYGQVL YRLERYDECL AVYRDLVRNS QDDYDEERKT NLSAVVAAQS N WEKVVPEN LGLQEGTHEL CYNTACALIG QGQLNQAMKI LQKAEDLCRR SLSEDTDGTE EDPQAELAII HGQMAYILQL QG RTEEALQ LYNQIIKLKP TDVGLLAVIA NNIITINKDQ NVFDSKKKVK LTNAEGVEFK LSKKQLQAIE FNKALLAMYT NQA EQCRKI SASLQSQSPE HLLPVLIQAA QLCREKQHTK AIELLQEFSD QHPENAAEIK LTMAQLKISQ GNISKACLIL RSIE ELKHK PGMVSALVTM YSHEEDIDSA IEVFTQAIQW YQNHQPKSPA HLSLIREAAN FKLKYGRKKE AISDLQQLWK QNPKD IHTL AQLISAYSLV DPEKAKALSK HLPSSDSMSL KVDVEALENS AGATYIRKKG GKVTGDSQPK EQGQGDLKKK KKKKKG KLP KNYDPKVTPD PERWLPMRER SYYRGRKKGK KKDQIGKGTQ GATAGASSEL DASKTVSSPP TSPRPGSAAT VSASTSN II PPRHQKPAGA PATKKKQQQK KKKGGKGGW

UniProtKB: Signal recognition particle subunit SRP72

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分子 #56: ZINC ION

分子名称: ZINC ION / タイプ: ligand / ID: 56 / コピー数: 5 / 式: ZN
分子量理論値: 65.409 Da

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分子 #57: MAGNESIUM ION

分子名称: MAGNESIUM ION / タイプ: ligand / ID: 57 / コピー数: 2 / 式: MG
分子量理論値: 24.305 Da

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分子 #58: GUANOSINE-5'-TRIPHOSPHATE

分子名称: GUANOSINE-5'-TRIPHOSPHATE / タイプ: ligand / ID: 58 / コピー数: 1 / 式: GTP
分子量理論値: 523.18 Da
Chemical component information

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP / GTP, エネルギー貯蔵分子*YM

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分子 #59: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

分子名称: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / タイプ: ligand / ID: 59 / コピー数: 1 / 式: GNP
分子量理論値: 522.196 Da
Chemical component information

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / Gpp(NH)p / GppNHp, GMPPNP, エネルギー貯蔵分子類似体*YM

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実験情報

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構造解析

手法クライオ電子顕微鏡法
解析単粒子再構成法
試料の集合状態particle

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試料調製

緩衝液pH: 7.5
グリッドモデル: Quantifoil R2/2 / 材質: COPPER / 支持フィルム - 材質: CARBON / 支持フィルム - トポロジー: CONTINUOUS / 前処理 - タイプ: GLOW DISCHARGE / 前処理 - 時間: 15 sec.
凍結凍結剤: ETHANE-PROPANE / 装置: FEI VITROBOT MARK IV
詳細in-vitro translation system

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電子顕微鏡法

顕微鏡TFS KRIOS
撮影フィルム・検出器のモデル: GATAN K3 (6k x 4k) / 平均電子線量: 50.0 e/Å2
電子線加速電圧: 300 kV / 電子線源: FIELD EMISSION GUN
電子光学系照射モード: FLOOD BEAM / 撮影モード: BRIGHT FIELD / Cs: 2.7 mm / 倍率（公称値）: 81000
試料ステージ試料ホルダーモデル: FEI TITAN KRIOS AUTOGRID HOLDER
ホルダー冷却材: NITROGEN
実験機器
モデル: Titan Krios / 画像提供: FEI Company

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画像解析

初期モデルモデルのタイプ: INSILICO MODEL / In silico モデル: using SGD from particles
最終 再構成解像度のタイプ: BY AUTHOR / 解像度: 3.2 Å / 解像度の算出法: FSC 0.143 CUT-OFF / 使用した粒子像数: 32881
初期 角度割当タイプ: PROJECTION MATCHING / ソフトウェア - 名称: RELION
最終 角度割当タイプ: MAXIMUM LIKELIHOOD / ソフトウェア - 名称: RELION

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万見について

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お知らせ

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2022年2月9日: EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

EMDBエントリの付随情報ファイルのフォーマットが新しくなりました

  • EMDBのヘッダファイルのバージョン3が、公式のフォーマットとなりました。
  • これまでは公式だったバージョン1.9は、アーカイブから削除されます。

関連情報:EMDBヘッダ

外部リンク:wwPDBはEMDBデータモデルのバージョン3へ移行します

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2020年8月12日: 新型コロナ情報

新型コロナ情報

URL: https://pdbjlvh1.pdbj.org/emnavi/covid19.php

新ページ: EM Navigatorに新型コロナウイルスの特設ページを開設しました。

関連情報:Covid-19情報 / 2020年3月5日: 新型コロナウイルスの構造データ

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2020年3月5日: 新型コロナウイルスの構造データ

新型コロナウイルスの構造データ

関連情報:万見生物種 / 2020年8月12日: 新型コロナ情報

外部リンク:COVID-19特集ページ - PDBj / 今月の分子2020年2月：コロナウイルスプロテーアーゼ

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2019年1月31日: EMDBのIDの桁数の変更

EMDBのIDの桁数の変更

  • EMDBエントリに付与されているアクセスコード(EMDB-ID)は4桁の数字(例、EMD-1234)でしたが、間もなく枯渇します。これまでの4桁のID番号は4桁のまま変更されませんが、4桁の数字を使い切った後に発行されるIDは5桁以上の数字(例、EMD-12345)になります。5桁のIDは2019年の春頃から発行される見通しです。
  • EM Navigator/万見では、接頭語「EMD-」は省略されています。

関連情報:Q: 「EMD」とは何ですか？ / 万見/EM NavigatorにおけるID/アクセスコードの表記

外部リンク:EMDB Accession Codes are Changing Soon! / PDBjへお問い合わせ

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2017年7月12日: PDB大規模アップデート

PDB大規模アップデート

  • 新バージョンのPDBx/mmCIF辞書形式に基づくデータがリリースされました。
  • 今回の更新はバージョン番号が4から5になる大規模なもので、全エントリデータの書き換えが行われる「Remediation」というアップデートに該当します。
  • このバージョンアップで、電子顕微鏡の実験手法に関する多くの項目の書式が改定されました(例：em_softwareなど)。
  • EM NavigatorとYorodumiでも、この改定に基づいた表示内容になります。

外部リンク:wwPDB Remediation / OneDepデータ基準に準拠した、より強化された内容のモデル構造ファイルが、PDBアーカイブで公開されました。

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万見 (Yorodumi)

幾万の構造データを、幾万の視点から

  • 万見(Yorodumi)は、EMDB/PDB/SASBDBなどの構造データを閲覧するためのページです。
  • EM Navigatorの詳細ページの後継、Omokage検索のフロントエンドも兼ねています。

関連情報:EMDB / PDB / SASBDB / 3つのデータバンクの比較 / 万見検索 / 2016年8月31日: 新しいEM Navigatorと万見 / 万見文献 / Jmol/JSmol / 機能・相同性情報 / 新しいEM Navigatorと万見の変更点

他の情報も見る