+Open data
-Basic information
Entry | Database: PDB / ID: 7n8m | |||||||||
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Title | PptT PAP(CoA) 8978B complex | |||||||||
Components | 4'-phosphopantetheinyl transferase PptT | |||||||||
Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Inhibitor / Structural Genomics / PSI-Biology / TB Structural Genomics Consortium / TBSGC / TRANSFERASE / TRANSFERASE-TRANSFERASE INHIBITOR complex | |||||||||
Function / homology | Function and homology information siderophore metabolic process / enterobactin synthetase complex / holo-[acyl-carrier-protein] synthase / enterobactin biosynthetic process / siderophore biosynthetic process / holo-[acyl-carrier-protein] synthase activity / magnesium ion binding / plasma membrane Similarity search - Function | |||||||||
Biological species | Mycobacterium tuberculosis (bacteria) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.57 Å | |||||||||
Authors | Mosior, J.W. / Sacchettini, J.C. / TB Structural Genomics Consortium (TBSGC) | |||||||||
Funding support | United States, 2items
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Citation | Journal: J.Med.Chem. / Year: 2022 Title: In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas. Authors: Ottavi, S. / Scarry, S.M. / Mosior, J. / Ling, Y. / Roberts, J. / Singh, A. / Zhang, D. / Goullieux, L. / Roubert, C. / Bacque, E. / Lagiakos, H.R. / Vendome, J. / Moraca, F. / Li, K. / ...Authors: Ottavi, S. / Scarry, S.M. / Mosior, J. / Ling, Y. / Roberts, J. / Singh, A. / Zhang, D. / Goullieux, L. / Roubert, C. / Bacque, E. / Lagiakos, H.R. / Vendome, J. / Moraca, F. / Li, K. / Perkowski, A.J. / Ramesh, R. / Bowler, M.M. / Tracy, W. / Feher, V.A. / Sacchettini, J.C. / Gold, B.S. / Nathan, C.F. / Aube, J. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7n8m.cif.gz | 145.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7n8m.ent.gz | 89.9 KB | Display | PDB format |
PDBx/mmJSON format | 7n8m.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7n8m_validation.pdf.gz | 2.2 MB | Display | wwPDB validaton report |
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Full document | 7n8m_full_validation.pdf.gz | 2.2 MB | Display | |
Data in XML | 7n8m_validation.xml.gz | 24 KB | Display | |
Data in CIF | 7n8m_validation.cif.gz | 35.3 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/n8/7n8m ftp://data.pdbj.org/pub/pdb/validation_reports/n8/7n8m | HTTPS FTP |
-Related structure data
Related structure data | 7n8eC 7n8lC 6ct5S S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Components on special symmetry positions |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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