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Yorodumi- PDB-7aq1: Crystal structure of human mature meprin beta in complex with the... -
+Open data
-Basic information
Entry | Database: PDB / ID: 7aq1 | ||||||
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Title | Crystal structure of human mature meprin beta in complex with the specific inhibitor MWT-S-270 | ||||||
Components | Meprin B subunit beta | ||||||
Keywords | HYDROLASE / Astacin protease / Metalloproteinase / Zn dependent / Sheddase / gamma Secretase / Inhbibitor bound Meprin beta holoenzyme / intermolecular disulfide bridge Homodimer / Glycoprotein | ||||||
Function / homology | Function and homology information meprin B / meprin A complex / metalloendopeptidase activity / inflammatory response / proteolysis / zinc ion binding / extracellular region / identical protein binding / plasma membrane Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.413 Å | ||||||
Authors | Linnert, M. / Parthier, C. / Fritz, C. | ||||||
Citation | Journal: Int J Mol Sci / Year: 2021 Title: Structure and Dynamics of Meprin beta in Complex with a Hydroxamate-Based Inhibitor. Authors: Linnert, M. / Fritz, C. / Jager, C. / Schlenzig, D. / Ramsbeck, D. / Kleinschmidt, M. / Wermann, M. / Demuth, H.U. / Parthier, C. / Schilling, S. #1: Journal: Preprints / Year: 2021 Title: Structure and Dynamics of Meprin beta in Complex with a Hydroxamate-Based Inhibitor Authors: Linnert, M. / Fritz, C. / Jager, C. / Schlenzig, D. / Ramsbeck, D. / Kleinschmidt, M. / Wermann, M. / Demuth, H.-U. / Schilling, S. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 7aq1.cif.gz | 638.4 KB | Display | PDBx/mmCIF format |
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PDB format | pdb7aq1.ent.gz | 538.2 KB | Display | PDB format |
PDBx/mmJSON format | 7aq1.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 7aq1_validation.pdf.gz | 2.5 MB | Display | wwPDB validaton report |
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Full document | 7aq1_full_validation.pdf.gz | 2.5 MB | Display | |
Data in XML | 7aq1_validation.xml.gz | 43.7 KB | Display | |
Data in CIF | 7aq1_validation.cif.gz | 61.7 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/aq/7aq1 ftp://data.pdbj.org/pub/pdb/validation_reports/aq/7aq1 | HTTPS FTP |
-Related structure data
Related structure data | 4gwnS S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Components on special symmetry positions |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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