- PDB-6kzc: crystal structure of TRKc in complex with 3-(imidazo[1,2-a]pyrazi... -
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基本情報
登録情報
データベース: PDB / ID: 6kzc
タイトル
crystal structure of TRKc in complex with 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methyl-N-(3-((4- methylpiperazin-1-yl)methyl)-5- (trifluoromethyl)phenyl)benzamide
要素
NT-3 growth factor receptor
キーワード
TRANSFERASE / TRKc
機能・相同性
機能・相同性情報
NTF3 activates NTRK3 signaling / Activated NTRK3 signals through PLCG1 / Signaling by NTRK3 (TRKC) / Receptor-type tyrosine-protein phosphatases / NTRK3 as a dependence receptor / neurotrophin receptor activity / neurotrophin binding / Activated NTRK3 signals through PI3K / activation of GTPase activity / positive regulation of positive chemotaxis ...NTF3 activates NTRK3 signaling / Activated NTRK3 signals through PLCG1 / Signaling by NTRK3 (TRKC) / Receptor-type tyrosine-protein phosphatases / NTRK3 as a dependence receptor / neurotrophin receptor activity / neurotrophin binding / Activated NTRK3 signals through PI3K / activation of GTPase activity / positive regulation of positive chemotaxis / Activated NTRK3 signals through RAS / cell surface receptor protein tyrosine kinase signaling pathway / activation of protein kinase B activity / transmembrane receptor protein tyrosine kinase activity / cellular response to nerve growth factor stimulus / negative regulation of protein phosphorylation / positive regulation of MAP kinase activity / receptor protein-tyrosine kinase / positive regulation of neuron projection development / p53 binding / positive regulation of peptidyl-serine phosphorylation / nervous system development / heart development / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / cell differentiation / receptor complex / positive regulation of cell migration / positive regulation of protein phosphorylation / axon / positive regulation of cell population proliferation / positive regulation of gene expression / ATP binding / plasma membrane 類似検索 - 分子機能