+Open data
-Basic information
Entry | Database: PDB / ID: 5twx | ||||||
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Title | Crystal Structure of BRD9 bromodomain | ||||||
Components | Bromodomain-containing protein 9 | ||||||
Keywords | TRANSCRIPTION / bromodomain / inhibitor / chemical degradation | ||||||
Function / homology | Function and homology information GBAF complex / SWI/SNF complex / positive regulation of stem cell population maintenance / negative regulation of cell differentiation / lysine-acetylated histone binding / nucleic acid binding / chromatin remodeling / positive regulation of cell population proliferation / regulation of transcription by RNA polymerase II / chromatin ...GBAF complex / SWI/SNF complex / positive regulation of stem cell population maintenance / negative regulation of cell differentiation / lysine-acetylated histone binding / nucleic acid binding / chromatin remodeling / positive regulation of cell population proliferation / regulation of transcription by RNA polymerase II / chromatin / nucleoplasm / nucleus Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 2.55 Å | ||||||
Authors | Seo, H.-S. / Dhe-Paganon, S. | ||||||
Citation | Journal: Angew. Chem. Int. Ed. Engl. / Year: 2017 Title: Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Authors: Remillard, D. / Buckley, D.L. / Paulk, J. / Brien, G.L. / Sonnett, M. / Seo, H.S. / Dastjerdi, S. / Wuhr, M. / Dhe-Paganon, S. / Armstrong, S.A. / Bradner, J.E. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 5twx.cif.gz | 195.8 KB | Display | PDBx/mmCIF format |
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PDB format | pdb5twx.ent.gz | 157.5 KB | Display | PDB format |
PDBx/mmJSON format | 5twx.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 5twx_validation.pdf.gz | 1.3 MB | Display | wwPDB validaton report |
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Full document | 5twx_full_validation.pdf.gz | 1.3 MB | Display | |
Data in XML | 5twx_validation.xml.gz | 22.7 KB | Display | |
Data in CIF | 5twx_validation.cif.gz | 27.6 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/tw/5twx ftp://data.pdbj.org/pub/pdb/validation_reports/tw/5twx | HTTPS FTP |
-Related structure data
Related structure data | 4yydS S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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