登録情報 | データベース: PDB / ID: 5f4p |
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タイトル | HIV-1 gp120 complex with BNM-III-170 |
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要素 | ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C |
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キーワード | VIRAL PROTEIN |
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機能・相同性 | 機能・相同性情報
positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / viral protein processing / fusion of virus membrane with host plasma membrane / virus-mediated perturbation of host defense response / fusion of virus membrane with host endosome membrane / viral envelope ...positive regulation of plasma membrane raft polarization / positive regulation of receptor clustering / positive regulation of establishment of T cell polarity / host cell endosome membrane / clathrin-dependent endocytosis of virus by host cell / viral protein processing / fusion of virus membrane with host plasma membrane / virus-mediated perturbation of host defense response / fusion of virus membrane with host endosome membrane / viral envelope / virion attachment to host cell / apoptotic process / host cell plasma membrane / structural molecule activity / virion membrane / plasma membrane類似検索 - 分子機能 HIV Envelope Protein Gp120; Chain G / Human immunodeficiency virus 1, Gp160, envelope glycoprotein / Envelope glycoprotein Gp160 / Retroviral envelope protein / Retroviral envelope protein GP41-like / Gp120 core superfamily / Envelope glycoprotein GP120 / Human immunodeficiency virus 1, envelope glycoprotein Gp120 / Beta Complex / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_virus.gif) Human immunodeficiency virus 1 (ヒト免疫不全ウイルス) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.6 Å |
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データ登録者 | Liang, S. / Hendrickson, W.A. |
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引用 | ジャーナル: Acs Med.Chem.Lett. / 年: 2016 タイトル: Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition. 著者: Melillo, B. / Liang, S. / Park, J. / Schon, A. / Courter, J.R. / LaLonde, J.M. / Wendler, D.J. / Princiotto, A.M. / Seaman, M.S. / Freire, E. / Sodroski, J. / Madani, N. / Hendrickson, W.A. / Smith, A.B. |
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履歴 | 登録 | 2015年12月3日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2016年3月30日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2020年7月29日 | Group: Data collection / Derived calculations / Structure summary カテゴリ: chem_comp / entity ...chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / pdbx_struct_oper_list / struct_site / struct_site_gen Item: _chem_comp.name / _chem_comp.type ..._chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _pdbx_struct_oper_list.symmetry_operation 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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改定 1.2 | 2023年9月27日 | Group: Data collection / Database references ...Data collection / Database references / Refinement description / Structure summary カテゴリ: chem_comp / chem_comp_atom ...chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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