登録情報 データベース : PDB / ID : 4jzi 構造の表示 ダウンロードとリンクタイトル Crystal Structure of Matriptase in complex with Inhibitor". 要素Suppressor of tumorigenicity 14 protein 詳細 キーワード HYDROLASE / MATRIPTASE / INHIBITOR / COMPLEX STRUCTURE機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
matriptase / epithelial cell morphogenesis involved in placental branching / Formation of the cornified envelope / keratinocyte differentiation / serine-type peptidase activity / neural tube closure / protein catabolic process / basolateral plasma membrane / external side of plasma membrane / serine-type endopeptidase activity ... matriptase / epithelial cell morphogenesis involved in placental branching / Formation of the cornified envelope / keratinocyte differentiation / serine-type peptidase activity / neural tube closure / protein catabolic process / basolateral plasma membrane / external side of plasma membrane / serine-type endopeptidase activity / proteolysis / extracellular space / plasma membrane 類似検索 - 分子機能 Peptidase S1A, matripase / SEA domain superfamily / SEA domain profile. / SEA domain / SEA domain / CUB domain / Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. / CUB domain / CUB domain profile. / Spermadhesin, CUB domain superfamily ... Peptidase S1A, matripase / SEA domain superfamily / SEA domain profile. / SEA domain / SEA domain / CUB domain / Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. / CUB domain / CUB domain profile. / Spermadhesin, CUB domain superfamily / Low-density lipoprotein receptor domain class A / Low-density lipoprotein (LDL) receptor class A, conserved site / LDL-receptor class A (LDLRA) domain signature. / LDL-receptor class A (LDLRA) domain profile. / Low-density lipoprotein receptor domain class A / Low-density lipoprotein (LDL) receptor class A repeat / LDL receptor-like superfamily / Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Serine proteases, trypsin family, serine active site. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Trypsin-like serine proteases / Thrombin, subunit H / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / Beta Barrel / Mainly Beta 類似検索 - ドメイン・相同性 Chem-N4C / Suppressor of tumorigenicity 14 protein 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / 分子置換 / 解像度 : 2 Å 詳細データ登録者 Subramanya, H.S. / Chandra, R.B. / Ashok, K.N. / Chakshusmathi, G. / Ramesh, K.S. 引用ジャーナル : ACS MED.CHEM.LETT. / 年 : 2013タイトル : Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors著者 : Goswami, R. / Mukherjee, S. / Wohlfahrt, G. / Ghadiyaram, C. / Nagaraj, J. / Chandra, B.R. / Sistla, R.K. / Satyam, L.K. / Samiulla, D.S. / Moilanen, A. / Subramanya, H.S. / Ramachandra, M. 履歴 登録 2013年4月3日 登録サイト : RCSB / 処理サイト : PDBJ改定 1.0 2014年2月26日 Provider : repository / タイプ : Initial release改定 1.1 2015年2月25日 Group : Database references改定 1.2 2023年11月8日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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