登録情報 | データベース: EMDB / ID: EMD-45178 |
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タイトル | Cryo-EM structure of Danio rerio voltage-sensing phosphatase (VSP) phosphatase domain |
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マップデータ | Sharpened map |
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試料 | - 複合体: Voltage-sensing phosphatase (Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2) in lipid nanodisc
- タンパク質・ペプチド: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2
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キーワード | phosphatase / voltage-sensing / MEMBRANE PROTEIN |
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機能・相同性 | 機能・相同性情報
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity / phosphatidylinositol dephosphorylation / regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / regulation of endocytosis / dephosphorylation / protein-tyrosine-phosphatase / protein tyrosine phosphatase activity / cell projection / cell motility / monoatomic ion channel activity ...phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity / phosphatidylinositol dephosphorylation / regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / regulation of endocytosis / dephosphorylation / protein-tyrosine-phosphatase / protein tyrosine phosphatase activity / cell projection / cell motility / monoatomic ion channel activity / negative regulation of cell population proliferation / nucleus / plasma membrane / cytosol類似検索 - 分子機能 TPTE, protein tyrosine phosphatase-like catalytic domain / Tensin phosphatase, C2 domain / Tensin-type phosphatase domain / C2 domain of PTEN tumour-suppressor protein / Phosphatase tensin-type domain profile. / C2 tensin-type domain profile. / C2 domain of PTEN tumour-suppressor protein / Voltage-dependent channel domain superfamily / Protein-tyrosine phosphatase, catalytic / Protein tyrosine phosphatase, catalytic domain motif ...TPTE, protein tyrosine phosphatase-like catalytic domain / Tensin phosphatase, C2 domain / Tensin-type phosphatase domain / C2 domain of PTEN tumour-suppressor protein / Phosphatase tensin-type domain profile. / C2 tensin-type domain profile. / C2 domain of PTEN tumour-suppressor protein / Voltage-dependent channel domain superfamily / Protein-tyrosine phosphatase, catalytic / Protein tyrosine phosphatase, catalytic domain motif / Tyrosine specific protein phosphatases active site. / Protein-tyrosine phosphatase, active site / Tyrosine-specific protein phosphatases domain / Tyrosine specific protein phosphatases domain profile. / Protein-tyrosine phosphatase-like / C2 domain superfamily / Ion transport domain / Ion transport protein類似検索 - ドメイン・相同性 Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2類似検索 - 構成要素 |
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生物種 | ![](img/tx_fish.gif) Danio rerio (ゼブラフィッシュ) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 2.97 Å |
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データ登録者 | Zhang L / Brohawn SG |
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資金援助 | 米国, 1件 Organization | Grant number | 国 |
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National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | GM145869 | 米国 |
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引用 | ジャーナル: To Be Published タイトル: Coupling sensor to enzyme in the voltage sensing phosphatase 著者: Yu Y / Zhang L / Li B / Fu Z / Brohawn SG / Isacoff EY |
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履歴 | 登録 | 2024年6月3日 | - |
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ヘッダ(付随情報) 公開 | 2024年7月10日 | - |
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マップ公開 | 2024年7月10日 | - |
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更新 | 2024年7月10日 | - |
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現状 | 2024年7月10日 | 処理サイト: RCSB / 状態: 公開 |
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