登録情報 | データベース: EMDB / ID: EMD-42462 |
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タイトル | Human Plasminogen bound to streptococcal surface enolase |
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マップデータ | Main map of human plasminogen bound to SEN on the surface of a lipid |
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試料 | - 複合体: Human plasminogen bound to streptococcal enolase on the surface of a lipid vesicle
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キーワード | Glycolysis / plasminogen binder / membrane protein / LYASE |
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機能・相同性 | 機能・相同性情報
plasmin / trans-synaptic signaling by BDNF, modulating synaptic transmission / trophoblast giant cell differentiation / tissue remodeling / protein antigen binding / tissue regeneration / mononuclear cell migration / Signaling by PDGF / negative regulation of cell-cell adhesion mediated by cadherin / positive regulation of fibrinolysis ...plasmin / trans-synaptic signaling by BDNF, modulating synaptic transmission / trophoblast giant cell differentiation / tissue remodeling / protein antigen binding / tissue regeneration / mononuclear cell migration / Signaling by PDGF / negative regulation of cell-cell adhesion mediated by cadherin / positive regulation of fibrinolysis / Dissolution of Fibrin Clot / negative regulation of cell-substrate adhesion / myoblast differentiation / biological process involved in interaction with symbiont / labyrinthine layer blood vessel development / muscle cell cellular homeostasis / Activation of Matrix Metalloproteinases / apolipoprotein binding / extracellular matrix disassembly / positive regulation of blood vessel endothelial cell migration / negative regulation of fibrinolysis / fibrinolysis / Degradation of the extracellular matrix / serine-type peptidase activity / platelet alpha granule lumen / Schaffer collateral - CA1 synapse / kinase binding / Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) / blood coagulation / Platelet degranulation / protein-folding chaperone binding / collagen-containing extracellular matrix / endopeptidase activity / protease binding / blood microparticle / negative regulation of cell population proliferation / protein domain specific binding / external side of plasma membrane / serine-type endopeptidase activity / signaling receptor binding / glutamatergic synapse / enzyme binding / cell surface / proteolysis / extracellular space / extracellular exosome / extracellular region / plasma membrane類似検索 - 分子機能 Peptidase S1A, plasmin / divergent subfamily of APPLE domains / PAN/Apple domain profile. / PAN domain / PAN/Apple domain / Kringle domain / Kringle / Kringle, conserved site / Kringle superfamily / Kringle domain signature. ...Peptidase S1A, plasmin / divergent subfamily of APPLE domains / PAN/Apple domain profile. / PAN domain / PAN/Apple domain / Kringle domain / Kringle / Kringle, conserved site / Kringle superfamily / Kringle domain signature. / Kringle domain profile. / Kringle domain / Kringle-like fold / Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Serine proteases, trypsin family, serine active site. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.6 Å |
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データ登録者 | Tjia-Fleck S / Readnour BM / Castellino FJ |
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資金援助 | 米国, 1件 Organization | Grant number | 国 |
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National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI) | HL013423 | 米国 |
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引用 | ジャーナル: To Be Published タイトル: Streptococcus surface alpha enolase exposed dimers were found to be the active form on lipid surface that binds to human plasminogen 著者: Tjia-Fleck S / Readnour BM / Castellino FJ |
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履歴 | 登録 | 2023年10月23日 | - |
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ヘッダ(付随情報) 公開 | 2024年6月12日 | - |
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マップ公開 | 2024年6月12日 | - |
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更新 | 2024年6月12日 | - |
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現状 | 2024年6月12日 | 処理サイト: RCSB / 状態: 公開 |
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