登録情報 | データベース: EMDB / ID: EMD-42050 |
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タイトル | Structure of eastern equine encephalitis virus VLP in complex with VLDLR LA1 |
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マップデータ | icosahedral asymmetrical unit subparticle map |
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試料 | - ウイルス:
![](img/tx_virus.gif) Eastern equine encephalitis virus (東部ウマ脳炎ウイルス)- 複合体: EEEV strain PE6 mature glycoprotein E1
- タンパク質・ペプチド: Envelope glycoprotein E1
- 複合体: EEEV strain PE6 mature glycoprotein E2
- タンパク質・ペプチド: Envelope glycoprotein E2
- 複合体: EEEV strain PE6 mature glycoprotein E3
- タンパク質・ペプチド: Envelope glycoprotein E3
- 複合体: EEEV strain PE6 mature capsid protein
- タンパク質・ペプチド: Capsid protein
- 複合体: VLDLR
- タンパク質・ペプチド: Very low-density lipoprotein receptor
- リガンド: 2-acetamido-2-deoxy-beta-D-glucopyranose
- リガンド: CALCIUM ION
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キーワード | Alphaviruses / Receptor / VIRUS LIKE PARTICLE |
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機能・相同性 | 機能・相同性情報
reelin receptor activity / VLDL clearance / glycoprotein transport / ventral spinal cord development / very-low-density lipoprotein particle receptor activity / Reelin signalling pathway / very-low-density lipoprotein particle binding / reelin-mediated signaling pathway / low-density lipoprotein particle receptor activity / very-low-density lipoprotein particle clearance ...reelin receptor activity / VLDL clearance / glycoprotein transport / ventral spinal cord development / very-low-density lipoprotein particle receptor activity / Reelin signalling pathway / very-low-density lipoprotein particle binding / reelin-mediated signaling pathway / low-density lipoprotein particle receptor activity / very-low-density lipoprotein particle clearance / togavirin / very-low-density lipoprotein particle / positive regulation of dendrite development / T=4 icosahedral viral capsid / lipid transport / dendrite morphogenesis / cargo receptor activity / apolipoprotein binding / clathrin-coated pit / VLDLR internalisation and degradation / cholesterol metabolic process / receptor-mediated endocytosis / memory / calcium-dependent protein binding / symbiont-mediated suppression of host gene expression / nervous system development / symbiont-mediated suppression of host toll-like receptor signaling pathway / host cell cytoplasm / receptor complex / symbiont entry into host cell / lysosomal membrane / serine-type endopeptidase activity / fusion of virus membrane with host endosome membrane / calcium ion binding / host cell nucleus / virion attachment to host cell / host cell plasma membrane / structural molecule activity / virion membrane / signal transduction / proteolysis / RNA binding / membrane / plasma membrane / cytoplasm類似検索 - 分子機能 : / Low-density lipoprotein receptor repeat class B / LDL-receptor class B (LDLRB) repeat profile. / LDLR class B repeat / Low-density lipoprotein-receptor YWTD domain / Alphavirus E2 glycoprotein, domain B / Peptidase S3, togavirin / Alphavirus E2 glycoprotein / Alphavirus E3 spike glycoprotein / Alphavirus E1 glycoprotein ...: / Low-density lipoprotein receptor repeat class B / LDL-receptor class B (LDLRB) repeat profile. / LDLR class B repeat / Low-density lipoprotein-receptor YWTD domain / Alphavirus E2 glycoprotein, domain B / Peptidase S3, togavirin / Alphavirus E2 glycoprotein / Alphavirus E3 spike glycoprotein / Alphavirus E1 glycoprotein / Alphavirus E2 glycoprotein, domain A / Alphavirus E2 glycoprotein, domain C / Alphavirus E2 glycoprotein / Alphavirus core protein / Alphavirus E3 glycoprotein / Alphavirus E1 glycoprotein / Alphavirus core protein (CP) domain profile. / Low-density lipoprotein receptor domain class A / : / Low-density lipoprotein (LDL) receptor class A, conserved site / LDL-receptor class A (LDLRA) domain signature. / LDL-receptor class A (LDLRA) domain profile. / Calcium-binding EGF domain / Low-density lipoprotein receptor domain class A / Low-density lipoprotein (LDL) receptor class A repeat / LDL receptor-like superfamily / Six-bladed beta-propeller, TolB-like / Coagulation Factor Xa inhibitory site / EGF-type aspartate/asparagine hydroxylation site / EGF-like calcium-binding, conserved site / Calcium-binding EGF-like domain signature. / Aspartic acid and asparagine hydroxylation site. / EGF-like calcium-binding domain / Calcium-binding EGF-like domain / Epidermal growth factor-like domain. / Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamily / Flavivirus glycoprotein, central and dimerisation domain superfamily / Flaviviral glycoprotein E, dimerisation domain / EGF-like domain profile. / EGF-like domain signature 2. / EGF-like domain / Immunoglobulin E-set / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan類似検索 - ドメイン・相同性 Structural polyprotein / Very low-density lipoprotein receptor / Structural polyprotein類似検索 - 構成要素 |
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生物種 | ![](img/tx_virus.gif) Eastern equine encephalitis virus (東部ウマ脳炎ウイルス) / Homo sapiens (ヒト) |
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手法 | 単粒子再構成法 / クライオ電子顕微鏡法 / 解像度: 3.58 Å |
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データ登録者 | Abraham J / Yang P / Li W / Fan X / Pan J |
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資金援助 | 米国, 1件 Organization | Grant number | 国 |
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Burroughs Wellcome Fund | | 米国 |
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引用 | ジャーナル: To Be Published タイトル: Structural basis for VLDLR recognition by eastern equine encephalitis virus 著者: Abraham J / Yang P / Li W / Fan X / Pan J |
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履歴 | 登録 | 2023年9月20日 | - |
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ヘッダ(付随情報) 公開 | 2024年8月14日 | - |
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マップ公開 | 2024年8月14日 | - |
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更新 | 2024年8月14日 | - |
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現状 | 2024年8月14日 | 処理サイト: RCSB / 状態: 公開 |
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