登録情報 | データベース: PDB / ID: 3d91 |
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タイトル | Human renin in complex with remikiren |
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要素 | Renin |
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キーワード | HYDROLASE / renin / remikiren / Alternative splicing / Aspartyl protease / Cleavage on pair of basic residues / Disease mutation / Glycoprotein / Membrane / Polymorphism / Protease / Secreted / Zymogen |
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機能・相同性 | 機能・相同性情報
renin / juxtaglomerular apparatus development / mesonephros development / response to cGMP / renin-angiotensin regulation of aldosterone production / drinking behavior / regulation of MAPK cascade / response to immobilization stress / angiotensin maturation / amyloid-beta metabolic process ...renin / juxtaglomerular apparatus development / mesonephros development / response to cGMP / renin-angiotensin regulation of aldosterone production / drinking behavior / regulation of MAPK cascade / response to immobilization stress / angiotensin maturation / amyloid-beta metabolic process / Metabolism of Angiotensinogen to Angiotensins / cell maturation / response to cAMP / hormone-mediated signaling pathway / kidney development / insulin-like growth factor receptor binding / regulation of blood pressure / male gonad development / cellular response to xenobiotic stimulus / apical part of cell / peptidase activity / response to lipopolysaccharide / aspartic-type endopeptidase activity / signaling receptor binding / proteolysis / extracellular space / extracellular region / plasma membrane類似検索 - 分子機能 Renin-like domain / Aspartic peptidase, N-terminal / A1 Propeptide / Eukaryotic aspartyl protease / Aspartic peptidase A1 family / Peptidase family A1 domain / Peptidase family A1 domain profile. / Cathepsin D, subunit A; domain 1 / Acid Proteases / Aspartic peptidase, active site ...Renin-like domain / Aspartic peptidase, N-terminal / A1 Propeptide / Eukaryotic aspartyl protease / Aspartic peptidase A1 family / Peptidase family A1 domain / Peptidase family A1 domain profile. / Cathepsin D, subunit A; domain 1 / Acid Proteases / Aspartic peptidase, active site / Eukaryotic and viral aspartyl proteases active site. / Aspartic peptidase domain superfamily / Beta Barrel / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.2 Å |
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データ登録者 | Prade, L. / Bezencon, O. / Bur, D. / Weller, T. / Fischli, W. / Remen, L. |
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引用 | #1: ジャーナル: Protein Expr.Purif. / 年: 1996タイトル: Recombinant human renin produced in different expression systems: biochemical properties and 3D structure 著者: Mathews, S. / Dobeli, H. / Pruschy, M. / Bosser, R. / D'Arcy, A. / Oefner, C. / Zulauf, M. / Gentz, R. / Breu, V. / Matile, H. / Schlaeger, J. / Fischli, W. |
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履歴 | 登録 | 2008年5月26日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2008年6月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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