登録情報 | データベース: PDB / ID: 3c0g |
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タイトル | CASK CaM-Kinase Domain- 3'-AMP complex, P1 form |
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要素 | Peripheral plasma membrane protein CASK |
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キーワード | TRANSFERASE / CASK / neurexin / Ca2+/calmodulin dependent protein kinase / Mg2+ / synaptic plasticity / pseudokinase / MAGUK / membrane-associated guanylate kinase / ATP-binding / Calmodulin-binding / Magnesium / Metal-binding / Nucleotide-binding / Nucleus / Serine/threonine-protein kinase / SH3 domain |
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機能・相同性 | 機能・相同性情報
negative regulation of cellular response to growth factor stimulus / guanylate kinase activity / neurexin family protein binding / Dopamine Neurotransmitter Release Cycle / regulation of neurotransmitter secretion / negative regulation of wound healing / nuclear lamina / Assembly and cell surface presentation of NMDA receptors / calcium ion import / Neurexins and neuroligins ...negative regulation of cellular response to growth factor stimulus / guanylate kinase activity / neurexin family protein binding / Dopamine Neurotransmitter Release Cycle / regulation of neurotransmitter secretion / negative regulation of wound healing / nuclear lamina / Assembly and cell surface presentation of NMDA receptors / calcium ion import / Neurexins and neuroligins / Nephrin family interactions / Sensory processing of sound by outer hair cells of the cochlea / Sensory processing of sound by inner hair cells of the cochlea / ciliary membrane / regulation of synaptic vesicle exocytosis / Syndecan interactions / negative regulation of cell-matrix adhesion / positive regulation of calcium ion import / basement membrane / negative regulation of keratinocyte proliferation / establishment of localization in cell / Schaffer collateral - CA1 synapse / nuclear matrix / cell-cell junction / protein localization / actin cytoskeleton / presynaptic membrane / basolateral plasma membrane / vesicle / calmodulin binding / non-specific serine/threonine protein kinase / cell adhesion / protein serine kinase activity / focal adhesion / protein serine/threonine kinase activity / signaling receptor binding / nucleolus / positive regulation of transcription by RNA polymerase II / ATP binding / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 CASK, SH3 domain / : / L27 domain, C-terminal / L27 domain / domain in receptor targeting proteins Lin-2 and Lin-7 / L27 domain / L27 domain profile. / L27 domain superfamily / Guanylate kinase, conserved site / Guanylate kinase-like signature. ...CASK, SH3 domain / : / L27 domain, C-terminal / L27 domain / domain in receptor targeting proteins Lin-2 and Lin-7 / L27 domain / L27 domain profile. / L27 domain superfamily / Guanylate kinase, conserved site / Guanylate kinase-like signature. / Guanylate kinase-like domain profile. / Guanylate kinase-like domain / Variant SH3 domain / Guanylate kinase/L-type calcium channel beta subunit / Guanylate kinase / Guanylate kinase homologues. / PDZ domain / PDZ domain profile. / Domain present in PSD-95, Dlg, and ZO-1/2. / PDZ domain / PDZ superfamily / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Protein kinase domain / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / P-loop containing nucleoside triphosphate hydrolase / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 Chem-3AM / Peripheral plasma membrane protein CASK類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.19 Å |
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データ登録者 | Wahl, M.C. |
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引用 | ジャーナル: Cell(Cambridge,Mass.) / 年: 2008 タイトル: CASK Functions as a Mg2+-independent neurexin kinase 著者: Mukherjee, K. / Sharma, M. / Urlaub, H. / Bourenkov, G.P. / Jahn, R. / Sudhof, T.C. / Wahl, M.C. |
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履歴 | 登録 | 2008年1月20日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2008年4月29日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Advisory / Version format compliance |
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改定 1.2 | 2024年3月13日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ncs_dom_lim / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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改定 1.3 | 2024年4月3日 | Group: Refinement description / カテゴリ: pdbx_initial_refinement_model |
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