- PDB-2xe5: Molecular insights into clinically isolated OmpC mutants and thei... -
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IDまたはキーワード:
読み込み中...
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基本情報
登録情報
データベース: PDB / ID: 2xe5
タイトル
Molecular insights into clinically isolated OmpC mutants and their role in multi-drug resistance (OmpC26)
要素
OUTER MEMBRANE PORIN C
キーワード
TRANSPORT PROTEIN / CELL MEMBRANE / ION TRANSPORT / PORIN
機能・相同性
機能・相同性情報
porin activity / pore complex / cell outer membrane / monoatomic ion transmembrane transport 類似検索 - 分子機能
Porin, gammaproteobacterial / Porin, Gram-negative type, conserved site / General diffusion Gram-negative porins signature. / Porin domain, Gram-negative type / Gram-negative porin / Porin, Gram-negative type / Porin / : / Porin domain superfamily / Porin ...Porin, gammaproteobacterial / Porin, Gram-negative type, conserved site / General diffusion Gram-negative porins signature. / Porin domain, Gram-negative type / Gram-negative porin / Porin, Gram-negative type / Porin / : / Porin domain superfamily / Porin / Beta Barrel / Mainly Beta 類似検索 - ドメイン・相同性
A: OUTER MEMBRANE PORIN C B: OUTER MEMBRANE PORIN C C: OUTER MEMBRANE PORIN C D: OUTER MEMBRANE PORIN C E: OUTER MEMBRANE PORIN C F: OUTER MEMBRANE PORIN C ヘテロ分子
THIS IS FROM A CLINICAL SEQUENCE DESCRIBED IN PUBMED ID: 11722730. A.S.LOW,F.M.MACKENZIE,I.M.GOULD, ...THIS IS FROM A CLINICAL SEQUENCE DESCRIBED IN PUBMED ID: 11722730. A.S.LOW,F.M.MACKENZIE,I.M.GOULD, I.R.BOOTH. PROTECTED ENVIRONMENTS ALLOW PARALLEL EVOLUTION OF A BACTERIAL PATHOGEN IN A PATIENT SUBJECTED TO LONG-TERM ANTIBIOTIC THERAPY. MOL.MICROBIOL. 42,619
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実験情報
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実験
実験
手法: X線回折 / 使用した結晶の数: 1
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試料調製
結晶
マシュー密度: 2.99 Å3/Da / 溶媒含有率: 58.8 % 解説: DATA WERE TRUNCATED USING WEBSERVER STRONG ET AL., 2006, PROC NATL ACAD SCI U S A, 103, 8060-5
解像度: 2.28→29.41 Å / Cor.coef. Fo:Fc: 0.904 / Cor.coef. Fo:Fc free: 0.875 / SU B: 15.665 / SU ML: 0.203 / 交差検証法: THROUGHOUT / ESU R: 0.491 / ESU R Free: 0.29 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. THIS USED REFMAC V5.6 WHICH HAS LOCAL NCS.
Rfactor
反射数
%反射
Selection details
Rfree
0.26707
4815
5 %
RANDOM
Rwork
0.22605
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obs
0.22804
95882
79.09 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.4 Å / 溶媒モデル: BABINET MODEL WITH MASK