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Structure paper

TitleCocrystal structure of human cytosolic phenylalanyl-tRNA synthetase and an inhibitor
Journal, issue, pagesTo Be Published
Publish dateApr 7, 2025 (structure data deposition date)
AuthorsQiao, H. / Hei, Z. / Fang, P.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3.33 - 3.4 Å
Structure data

PDB-9udl:
Cocrystal structure of human cytosolic phenylalanyl-tRNA synthetase and an inhibitor
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

PDB-9udm:
Cocrystal structure of human cytosolic phenylalanyl-tRNA synthetase and an inhibitor in the presence of ATP
Method: X-RAY DIFFRACTION / Resolution: 3.33 Å

Chemicals

ChemComp-LCF:
[6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YL]ACETIC ACID / antiinflammatory, inhibitor*YM

Source
  • homo sapiens (human)
KeywordsLIGASE / TRNA ligase / Inhibitor / Complex

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