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-Structure paper
| Title | Molecular basis of mitogen-activated protein kinase ERK2 activation by its upstream kinase MEK1 |
|---|---|
| Journal, issue, pages | Biorxiv, Year 2026 |
| Publish date | Jan 19, 2026 (structure data deposition date) |
Authors | von Velsen J / Juyoux P / Piasentin N / Fisher H / Lapouge K / Vadas O / Gervasio FL / Bowler MW |
External links | Biorxiv / Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.9 - 3.4 Å |
| Structure data | EMDB-56418, PDB-9tyg: EMDB-56419, PDB-9tyh: |
| Chemicals | ![]() ChemComp-ADP: ![]() ChemComp-MG: |
| Source |
|
Keywords | SIGNALING PROTEIN / protein kinases / phosphoryl transfer / MAPK / MAP2K / cancer signaling |
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homo sapiens (human)
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