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Structure paper

TitleAllosteric regulation of fibronectin binding by the anti-beta 1 integrin antibody TS2/16.
Journal, issue, pagesPnas Nexus, Vol. 5, Page pgag044-pgag044, Year 2026
Publish dateJun 19, 2025 (structure data deposition date)
AuthorsDing, J. / Fantini, D.A. / Dedden, D. / Schumacher, S. / Biertumpfel, C. / Mizuno, N.
External linksPnas Nexus / PubMed:41809771
MethodsEM (single particle)
Resolution2.61 Å
Structure data

PDB-9p6s:
Cryo-EM structure of human integrin alpha5beta1 in complex with fibronectin (FN 7-10)
Method: ELECTRON MICROSCOPY / Resolution: 2.61 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL ADHESION / a5b1 integrin / fibronectin / extracellular matrix / focal adhesion / single-particle

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