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-Structure paper
| Title | ML418 Binds in the Pore of the Inward Rectifier Kir7.1 and Inhibits the Channel In Vivo to Reduce Food Intake and Body Weight |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Mar 4, 2025 (structure data deposition date) |
Authors | Peisley A / Su M / Cone R |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 3.5 - 3.9 Å |
| Structure data | EMDB-49554, PDB-9nms: EMDB-49555, PDB-9nmt: |
| Chemicals | ![]() ChemComp-K: ![]() PDB-1by7: |
| Source |
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Keywords | MEMBRANE PROTEIN / inwardly rectifying potassium channel Kir7.1 / inwardly rectifying potassium channel Kir7.1 channel blocker ML418 |
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homo sapiens (human)
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