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TitleNeuroprotective potential of an engineered hormone with dual insulin and IGF-1 receptor activity
Journal, issue, pagesTo Be Published
Publish dateFeb 16, 2025 (structure data deposition date)
AuthorsSelicharova I / Kirk NS / Lubos M / Kertisova A / Mitrova K / Zakova L / Chrudinova M / Brezinova J / Harant K / Voldrich J ...Selicharova I / Kirk NS / Lubos M / Kertisova A / Mitrova K / Zakova L / Chrudinova M / Brezinova J / Harant K / Voldrich J / Panikova T / Torres-Aleman I / Huffman D / Jiracek J
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.4 Å
Structure data

49261

9nco

EMDB-49261, PDB-9nco:
IN-ML-15 bound to IGF1Rzip
Method: EM (single particle) / Resolution: 3.4 Å

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsSIGNALING PROTEIN / IGF receptor / insulin-like growth factor / insulin / IGF

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