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Structure paper

TitleConformational Landscape of HIV-1 Env from Closed to Fully Open
Journal, issue, pagesTo Be Published
Publish dateFeb 14, 2025 (structure data deposition date)
AuthorsCui J / Du J / Lin Z / Pallesen J
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.91 - 3.88 Å
Structure data

EMDB-49236, PDB-9nbt:
AMC008 v4.2 SOSIP Env trimer in complex with VRC01 and 35O22 Fabs
Method: EM (single particle) / Resolution: 2.91 Å

EMDB-49238, PDB-9nby:
AMC008 v4.2 SOSIP Env trimer in complex with PGT121, VRC01 and 3BC315 Fabs
Method: EM (single particle) / Resolution: 3.16 Å

EMDB-49239, PDB-9nc0:
AMC008 v4.2 SOSIP Env trimer in complex with b12 Fab
Method: EM (single particle) / Resolution: 3.88 Å

EMDB-49240, PDB-9nc3:
AMC008 v4.2 SOSIP Env trimer in complex with b12 and 3BC315 Fabs
Method: EM (single particle) / Resolution: 3.74 Å

EMDB-49241, PDB-9nc6:
AMC008 v4.2 SOSIP Env trimer in complex with two 3BC315 Fabs
Method: EM (single particle) / Resolution: 3.52 Å

EMDB-49242, PDB-9nc8:
AMC008 v4.2 SOSIP Env trimer in complex with one 3BC315 Fab
Method: EM (single particle) / Resolution: 3.55 Å

EMDB-70287, PDB-9oaj:
AMC008 v4.2 SOSIP Env trimer in complex with CD4 D1D2
Method: EM (single particle) / Resolution: 2.91 Å

EMDB-73342, PDB-9yqo:
AMC008 v4.2 SOSIP Env trimer in complex with PGT121 and VRC01 Fabs
Method: EM (single particle) / Resolution: 3.26 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • human immunodeficiency virus 1
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HIV-1 Envelope glycoprotein / broadly neutralizing antibodies / cluster of differentiation 4

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