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TitleCXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting
Journal, issue, pagesTo Be Published
Publish dateNov 15, 2024 (structure data deposition date)
AuthorsItoh-Nakadai A / Liang M / Ishikawa F
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.97 Å
Structure data

62427

9kmc

EMDB-62427, PDB-9kmc:
Cryo-EM structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 and anti-CD25 Fab S417
Method: EM (single particle) / Resolution: 2.97 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • sythetic construct (others)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / CYTOKINE

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