Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Crystallographic Fragment Screening of a Bifunctional Proline Catabolic Enzyme Reveals New Inhibitor Templates for Proline Dehydrogenase and L-Glutamate-gamma-semialdehyde Dehydrogenase.
Journal, issue, pages	Molecules, Vol. 29, Year 2024
Publish date	Sep 10, 2024 (structure data deposition date)
Authors	Meeks, K.R. / Bogner, A.N. / Nix, J.C. / Tanner, J.J.
External links	Molecules / PubMed:39598797
Methods	X-ray diffraction
Resolution	1.32 - 1.8 Å
Structure data	PDB-9dl2: Structure of proline utilization A complexed with 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid Method: X-RAY DIFFRACTION / Resolution: 1.55 Å PDB-9dl3: Structure of proline utilization A complexed with quinoline-2-carboxylic acid Method: X-RAY DIFFRACTION / Resolution: 1.77 Å PDB-9dl4: Structure of proline utilization A complexed with 2-pyridinethiol Method: X-RAY DIFFRACTION / Resolution: 1.8 Å PDB-9dl5: Structure of proline utilization A complexed with 5-chloro-1-indanone Method: X-RAY DIFFRACTION / Resolution: 1.77 Å PDB-9dl6: Structure of proline utilization A complexed with piperidine-3-carboxylic acid Method: X-RAY DIFFRACTION / Resolution: 1.42 Å PDB-9dl7: Structure of proline utilization A complexed with 1-(4-fluorophenyl)thiourea Method: X-RAY DIFFRACTION / Resolution: 1.72 Å PDB-9dl8: Structure of proline utilization A soaked with 4-methoxybenzyl alcohol Method: X-RAY DIFFRACTION / Resolution: 1.64 Å PDB-9dl9: Structure of proline utilization A co-crystallized with 4-methoxybenzyl alcohol Method: X-RAY DIFFRACTION / Resolution: 1.32 Å PDB-9e0a: Structure of proline utilization A complexed with 1,4-benzenedimethanol Method: X-RAY DIFFRACTION / Resolution: 1.39 Å PDB-9e0b: Structure of proline utilization A complexed with (2,3-dihydro-1-benzofuran-5-yl)methanol Method: X-RAY DIFFRACTION / Resolution: 1.47 Å PDB-9e0c: Structure of proline utilization A complexed with 1-benzofuran-5-ylmethanol Method: X-RAY DIFFRACTION / Resolution: 1.32 Å PDB-9e0d: Structure of proline utilization A complexed with piperonyl alcohol Method: X-RAY DIFFRACTION / Resolution: 1.33 Å PDB-9e0e: Structure of proline utilization A complexed with (1H-indol-5-yl)methanol Method: X-RAY DIFFRACTION / Resolution: 1.37 Å
Chemicals	ChemComp-FAD: FLAVIN-ADENINE DINUCLEOTIDE / FADYM ChemComp-PEG: DI(HYDROXYETHYL)ETHER ChemComp-53E: 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid ChemComp-FMT: FORMIC ACID ChemComp-NAD: NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NADYM ChemComp-SO4: SULFATE ION ChemComp-MG: Unknown entry ChemComp-PGE: TRIETHYLENE GLYCOL ChemComp-PG4: TETRAETHYLENE GLYCOL / precipitantYM ChemComp-HOH: WATER ChemComp-QNC: quinoline-2-carboxylic acid ChemComp-PYS: 2-PYRIDINETHIOL PDB-1bda: CATALYTIC DOMAIN OF HUMAN SINGLE CHAIN TISSUE PLASMINOGEN ACTIVATOR IN COMPLEX WITH DANSYL-EGR-CMK (DANSYL-GLU-GLY-ARG CHLOROMETHYL KETONE) PDB-1bdb: CIS-BIPHENYL-2,3-DIHYDRODIOL-2,3-DEHYDROGENASE FROM PSEUDOMONAS SP. LB400 ChemComp-ID7: (3R)-piperidine-3-carboxylic acid ChemComp-8P4: 1-(4-fluorophenyl)thiourea PDB-1bdd: STAPHYLOCOCCUS AUREUS PROTEIN A, IMMUNOGLOBULIN-BINDING B DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE ChemComp-1PE: PENTAETHYLENE GLYCOL / precipitantYM PDB-1bdw: GRAMICIDIN D FROM BACILLUS BREVIS (ACTIVE FORM) PDB-1aqc: X11 PTB DOMAIN-10MER PEPTIDE COMPLEX PDB-1bdx: E. COLI DNA HELICASE RUVA WITH BOUND DNA HOLLIDAY JUNCTION, ALPHA CARBONS AND PHOSPHATE ATOMS ONLY PDB-1bdv: ARC FV10 COCRYSTAL PDB-1bdu: E. COLI THYMIDYLATE SYNTHASE COMPLEXED WITH DURD
Source	sinorhizobium meliloti (bacteria)
Keywords	OXIDOREDUCTASE / FLAVOENZYME / ROSSMANN FOLD / PROLINE DEHYDROGENASE / ALDEHYDE DEHYDROGENASE / PROLINE CATABOLISM / SUBSTRATE CHANNELING / BIFUNCTIONAL ENZYME