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TitleDiheteromeric GluN1/GluN2A (delM563) in nanodisc, in complex with glycine, glutamate, and GNE-4123, open-pore conformation
Journal, issue, pagesTo Be Published
Publish dateJun 10, 2024 (structure data deposition date)
AuthorsJalali-Yazdi F / Kim J / Gouaux E
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.1 Å
Structure data

45279

9c7c

EMDB-45279, PDB-9c7c:
Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open conformation
Method: EM (single particle) / Resolution: 3.1 Å

Chemicals

PDB-1auv:
STRUCTURE OF THE C DOMAIN OF SYNAPSIN IA FROM BOVINE BRAIN

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HP6:
HEPTANE

ChemComp-Y01:
CHOLESTEROL HEMISUCCINATE

ChemComp-GLY:
GLYCINE

ChemComp-D12:
DODECANE

ChemComp-GLU:
GLUTAMIC ACID

ChemComp-D10:
DECANE

ChemComp-HEX:
HEXANE

Source
  • rattus norvegicus (Norway rat)
  • aequorea victoria (jellyfish)
KeywordsTRANSPORT PROTEIN / ion channel / NMDA / positive allosteric modulator / open pore conformation

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