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-Structure paper
Title | Improved higher resolution Cryo-EM structures reveal the binding modes of hERG Channel Inhibitors |
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Journal, issue, pages | To Be Published |
Publish date | Jun 18, 2024 (structure data deposition date) |
Authors | Miyashita Y / Moriya T / Kato T / Kawasaki M / Yasuda Y / Adachi N / Suzuki K / Ogasawara S / Saito T / Senda T / Murata T |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 3.18 - 3.29 Å |
Structure data | EMDB-60573, PDB-8zyn: EMDB-60574, PDB-8zyo: EMDB-60575, PDB-8zyp: EMDB-60576, PDB-8zyq: |
Chemicals | ChemComp-XB7: PDB-1l2j: ChemComp-1II: |
Source |
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Keywords | TRANSPORT PROTEIN / drug toxicity / potassium ion / hERG / cryo-EM / MEMBRANE PROTEIN |