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Structure paper

TitleTIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 121, Page e2318794121-e2318794121, Year 2024
Publish dateOct 27, 2023 (structure data deposition date)
AuthorsNakamura, T. / Ohyama, C. / Sakamoto, M. / Toma, T. / Tateishi, H. / Matsuo, M. / Chirifu, M. / Ikemizu, S. / Morioka, H. / Fujita, M. ...Nakamura, T. / Ohyama, C. / Sakamoto, M. / Toma, T. / Tateishi, H. / Matsuo, M. / Chirifu, M. / Ikemizu, S. / Morioka, H. / Fujita, M. / Inoue, J.I. / Yamagata, Y.
External linksProc. Natl. Acad. Sci. USA / PubMed:38442163
MethodsX-ray diffraction
Resolution1.79 Å
Structure data

PDB-8wwy:
Crystal structure of mouse TIFA/TIFAB heterodimer
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

Chemicals

ChemComp-HX2:
(2R,5R)-hexane-2,5-diol

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN / Complex

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