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Structure paper

TitleCo-crystal structure of human TREX1 in complex with an inhibitor
Journal, issue, pagesTo be published
Publish dateJan 11, 2024 (structure data deposition date)
AuthorsDehghani-Tafti, S. / Dong, A. / Li, Y. / Xu, J. / Ackloo, S. / Arrowsmith, C.H. / Edwards, A.M. / Halabelian, L. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.88 - 2.3 Å
Structure data

PDB-8vl7:
Co-crystal structure of human TREX1 in complex with an inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-9ava:
Co-crystal structure of human TREX1 in complex with an inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

PDB-1acj:
QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-UNX:
Unknown entry

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-K:
Unknown entry

PDB-1ag1:
MONOHYDROGEN PHOSPHATE BINDING TO TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Trex1 / inhibitor / nuclease / SGC / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex / TRANSPORT PROTEIN

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