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-Structure paper
Title | SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain |
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Journal, issue, pages | Nat Commun, Year 2024 |
Publish date | Nov 6, 2023 (structure data deposition date) |
![]() | Hendrix S / Dartigue V / Hall H / Bawaria S / Kingma J / Bajaj B / Zelcer N / Kober DL |
![]() | ![]() |
Methods | EM (single particle) |
Resolution | 2.27 - 2.3 Å |
Structure data | EMDB-42639, PDB-8uw8: EMDB-42661, PDB-8uwc: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-CA: ![]() ChemComp-HOH: |
Source |
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![]() | SIGNALING PROTEIN / serine protease cholesterol metabolism zymogen activation Protein complex glycoprotein secretory pathway |