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-Structure paper
Title | Network of epistatic interactions in an enzyme active site revealed by large-scale deep mutational scanning. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 121, Page e2313513121-e2313513121, Year 2024 |
Publish date | Apr 17, 2023 (structure data deposition date) |
Authors | Judge, A. / Sankaran, B. / Hu, L. / Palaniappan, M. / Birgy, A. / Prasad, B.V.V. / Palzkill, T. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:38483989 |
Methods | X-ray diffraction |
Resolution | 1.5 Å |
Structure data | PDB-8sj3: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / beta-lactamase / enzyme / serine protease / antimicrobial resistance |