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Title14-3-3zeta binding increases cytosolic phospho-Tau solubility by decreasing its condensation, aggregation, and microtubule association
Journal, issue, pagesTo Be Published
Publish dateAug 30, 2023 (structure data deposition date)
AuthorsHochmair, J. / van den Oetelaar, M.C.M. / Ravatt, R. / Lemmens, L.J.M. / Ponce, R. / Semenova, E. / Mohapatra, S. / Ottmann, C. / Diez, L. / Brunsveld, L. / Wegmann, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-8qdv:
Structure of 14-3-3 zeta delta C with the bivalent tau-pS214-pS324 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / 14-3-3 zeta / tau / protein-protein interaction

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