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Title | A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the tau intrinsically disordered protein. |
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Journal, issue, pages | J. Biol. Chem., Vol. 300, Page 107163-107163, Year 2024 |
Publish date | Apr 6, 2023 (structure data deposition date) |
Authors | Mortelecque, J. / Zejneli, O. / Begard, S. / Simoes, M.C. / ElHajjar, L. / Nguyen, M. / Cantrelle, F.X. / Hanoulle, X. / Rain, J.C. / Colin, M. ...Mortelecque, J. / Zejneli, O. / Begard, S. / Simoes, M.C. / ElHajjar, L. / Nguyen, M. / Cantrelle, F.X. / Hanoulle, X. / Rain, J.C. / Colin, M. / Gomes, C.M. / Buee, L. / Landrieu, I. / Danis, C. / Dupre, E. |
External links | J. Biol. Chem. / PubMed:38484799 |
Methods | X-ray diffraction |
Resolution | 1.54 - 2.35 Å |
Structure data | PDB-8op0: PDB-8opi: PDB-8pii: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / VHH / nanobody / complex / Tau |