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-Structure paper
Title | Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: Implication in aromatic amino acid decarboxylase deficiency. |
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Journal, issue, pages | Protein Sci., Vol. 32, Page e4732-e4732, Year 2023 |
Publish date | Apr 13, 2023 (structure data deposition date) |
Authors | Bisello, G. / Ribeiro, R.P. / Perduca, M. / Belviso, B.D. / Polverino De' Laureto, P. / Giorgetti, A. / Caliandro, R. / Bertoldi, M. |
External links | Protein Sci. / PubMed:37466248 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.4 Å |
Structure data | PDB-8or9: PDB-8ora: |
Chemicals | ChemComp-PLP: ChemComp-PG4: ChemComp-HOH: ChemComp-W5I: |
Source |
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Keywords | LYASE / Dopa decarboxilase / Human aromatic amino acid decarboxylase / AADC deficiency / L-dopa / dopamine / pyridoxal phosphate / PLP / Melevodopa / dopa methylester / DME / Catalytic loop |