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TitleThe structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity.
Journal, issue, pagesFront Immunol, Vol. 14, Page 1190943-1190943, Year 2023
Publish dateMar 20, 2023 (structure data deposition date)
AuthorsNavas-Yuste, S. / de la Paz, K. / Querol-Garcia, J. / Gomez-Quevedo, S. / Rodriguez de Cordoba, S. / Fernandez, F.J. / Vega, M.C.
External linksFront Immunol / PubMed:37409124
MethodsX-ray diffraction
Resolution2.37 Å
Structure data

PDB-8oha:
Crystal structure of Leptospira interrogans GAPDH
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-HOH:
WATER

Source
  • leptospira interrogans serovar copenhageni str. fiocruz l1-130 (bacteria)
KeywordsHYDROLASE / GAPDH / Leptospira interrogans / Immune evasion / Innate immunity / Complement system

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