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Structure paper

TitleStructural basis for the allosteric pathway of 4-amino-4-deoxychorismate synthase.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 79, Page 895-908, Year 2023
Publish dateJan 4, 2023 (structure data deposition date)
AuthorsNakamichi, Y. / Kobayashi, J. / Toyoda, K. / Suda, M. / Hiraga, K. / Inui, M. / Watanabe, M.
External linksActa Crystallogr D Struct Biol / PubMed:37712435
MethodsX-ray diffraction
Resolution1.95 - 2.55 Å
Structure data

PDB-8hx6:
Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae
Method: X-RAY DIFFRACTION / Resolution: 2.14 Å

PDB-8hx7:
Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae co-crystallized with L-glutamine
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-8hx8:
Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae co-crystallized with chorismate
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-8hx9:
Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae with chorismate
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-TRP:
TRYPTOPHAN

ChemComp-MLT:
D-MALATE

ChemComp-MG:
Unknown entry

ChemComp-SIN:
SUCCINIC ACID

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-ISJ:
(3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid

ChemComp-GOL:
GLYCEROL

ChemComp-FMT:
FORMIC ACID

Source
  • streptomyces venezuelae (bacteria)
KeywordsTRANSFERASE / Synthase / Multi-domain / Chorismate

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